Motif ID: ACAGUAU

Z-value: 0.843


Mature miRNA associated with seed ACAGUAU:

NamemiRBase Accession
hsa-miR-144 MIMAT0000436



Activity profile for motif ACAGUAU.

activity profile for motif ACAGUAU


Sorted Z-values histogram for motif ACAGUAU

Sorted Z-values for motif ACAGUAU



Network of associatons between targets according to the STRING database.



First level regulatory network of ACAGUAU

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr6_+_126111782 2.737 NM_001122842
NM_001199621
NM_181782
 NCOA7


nuclear receptor coactivator 7


chr6_+_126240369 2.523 NM_001199622
 NCOA7
nuclear receptor coactivator 7
chr5_-_95297597 2.301 NM_012081
 ELL2
elongation factor, RNA polymerase II, 2
chr4_-_139163222 2.271 NM_014331
 SLC7A11
solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
chr6_+_126102278 2.257 NM_001199619
NM_001199620
 NCOA7

nuclear receptor coactivator 7

chr12_-_121734543 2.000 NM_172226
 CAMKK2
calcium/calmodulin-dependent protein kinase kinase 2, beta
chr5_+_127419407 1.834 NM_001046
 SLC12A2
solute carrier family 12 (sodium/potassium/chloride transporters), member 2
chr7_+_6144504 1.723 NM_032172
 USP42
ubiquitin specific peptidase 42
chr10_-_75335415 1.688 NM_152586
 USP54
ubiquitin specific peptidase 54
chr11_-_128457452 1.666 NM_001143820
 ETS1
v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)
chr11_-_128392061 1.572 NM_001162422
NM_005238
 ETS1

v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)

chr11_-_8832881 1.511 NM_139157
 ST5
suppression of tumorigenicity 5
chr11_-_8832189 1.432 NM_213618
 ST5
suppression of tumorigenicity 5
chr9_+_118916069 1.431 NM_002581
 PAPPA
pregnancy-associated plasma protein A, pappalysin 1
chr11_-_8932497 1.419 NM_005418
 ST5
suppression of tumorigenicity 5
chr1_+_169075869 1.417 NM_001677
 ATP1B1
ATPase, Na+/K+ transporting, beta 1 polypeptide
chr16_-_65155881 1.415 NM_001797
 CDH11
cadherin 11, type 2, OB-cadherin (osteoblast)
chr5_-_115910406 1.338 NM_020796
 SEMA6A
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
chr8_+_17354562 1.332 NM_001008539
 SLC7A2
solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
chr8_+_17396285 1.318 NM_001164771
NM_003046
 SLC7A2

solute carrier family 7 (cationic amino acid transporter, y+ system), member 2


Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 81 entries
enrichment   p-value GO term description
24.80 1.15e-02 GO:0016198 axon choice point recognition
7.97 2.17e-03 GO:0030509 BMP signaling pathway
5.32 2.16e-04 GO:0007178 transmembrane receptor protein serine/threonine kinase signaling pathway
4.06 8.10e-04 GO:0030900 forebrain development
2.87 4.01e-02 GO:0035295 tube development
2.85 1.21e-04 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
2.79 1.65e-02 GO:0007411 axon guidance
2.72 1.22e-05 GO:0045893 positive regulation of transcription, DNA-dependent
2.66 9.08e-04 GO:0031175 neuron projection development
2.66 1.05e-02 GO:0000122 negative regulation of transcription from RNA polymerase II promoter
2.63 1.36e-05 GO:0010628 positive regulation of gene expression
2.63 1.16e-03 GO:0000904 cell morphogenesis involved in differentiation
2.59 3.02e-05 GO:0051254 positive regulation of RNA metabolic process
2.57 9.07e-03 GO:0048812 neuron projection morphogenesis
2.56 3.16e-04 GO:0000902 cell morphogenesis
2.55 1.05e-05 GO:0010557 positive regulation of macromolecule biosynthetic process
2.53 1.79e-03 GO:0045892 negative regulation of transcription, DNA-dependent
2.51 2.81e-02 GO:0007409 axonogenesis
2.50 1.41e-07 GO:0006357 regulation of transcription from RNA polymerase II promoter
2.49 4.13e-04 GO:0032989 cellular component morphogenesis

Gene overrepresentation in compartment category:

Showing 1 to 3 of 3 entries
enrichment   p-value GO term description
1.41 2.81e-06 GO:0005634 nucleus
1.18 2.63e-05 GO:0005622 intracellular
1.17 9.23e-05 GO:0044424 intracellular part

Gene overrepresentation in function category:

Showing 1 to 19 of 19 entries
enrichment   p-value GO term description
6.61 8.14e-03 GO:0046332 SMAD binding
6.08 1.55e-02 GO:0004702 receptor signaling protein serine/threonine kinase activity
4.47 5.44e-03 GO:0005057 receptor signaling protein activity
3.02 3.64e-04 GO:0016563 transcription activator activity
2.88 1.42e-02 GO:0003702 RNA polymerase II transcription factor activity
2.73 8.00e-03 GO:0016564 transcription repressor activity
2.73 1.20e-02 GO:0008134 transcription factor binding
2.49 3.66e-03 GO:0004674 protein serine/threonine kinase activity
2.43 4.09e-05 GO:0043565 sequence-specific DNA binding
2.27 1.71e-06 GO:0030528 transcription regulator activity
2.24 4.70e-06 GO:0001071 nucleic acid binding transcription factor activity
2.24 4.70e-06 GO:0003700 sequence-specific DNA binding transcription factor activity
2.18 7.16e-03 GO:0004672 protein kinase activity
1.94 4.53e-02 GO:0016773 phosphotransferase activity, alcohol group as acceptor
1.53 9.96e-05 GO:0003676 nucleic acid binding
1.53 8.67e-03 GO:0000166 nucleotide binding
1.51 2.01e-02 GO:0003677 DNA binding
1.38 1.83e-08 GO:0005515 protein binding
1.19 2.26e-07 GO:0005488 binding