Motif ID: ACAUUCA

Z-value: 1.016


Mature miRNA associated with seed ACAUUCA:

NamemiRBase Accession
hsa-miR-181a MIMAT0000256
hsa-miR-181b MIMAT0000257
hsa-miR-181c MIMAT0000258
hsa-miR-181d MIMAT0002821
hsa-miR-4262 MIMAT0016894



Activity profile for motif ACAUUCA.

activity profile for motif ACAUUCA


Sorted Z-values histogram for motif ACAUUCA

Sorted Z-values for motif ACAUUCA



Network of associatons between targets according to the STRING database.



First level regulatory network of ACAUUCA

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_-_120549115 2.765 NM_033437
PDE5A
phosphodiesterase 5A, cGMP-specific
chr7_-_25019625 2.589 NM_015550
NM_145320
NM_145321
NM_145322
OSBPL3



oxysterol binding protein-like 3



chr7_-_47621741 2.555 NM_022748
TNS3
tensin 3
chr4_-_120549827 2.118 NM_001083
PDE5A
phosphodiesterase 5A, cGMP-specific
chr8_+_23386362 1.806 NM_016612
SLC25A37
solute carrier family 25, member 37
chr11_-_125933186 1.757 NM_001243597
NM_016952
CDON

Cdon homolog (mouse)

chr9_+_72658496 1.730 NM_153267
MAMDC2
MAM domain containing 2
chr4_-_120548329 1.699 NM_033430
PDE5A
phosphodiesterase 5A, cGMP-specific
chr5_-_141704575 1.620 NM_001127496
NM_030964
SPRY4

sprouty homolog 4 (Drosophila)

chr1_+_169075869 1.402 NM_001677
ATP1B1
ATPase, Na+/K+ transporting, beta 1 polypeptide
chr5_-_121414011 1.337 NM_002317
LOX
lysyl oxidase
chr5_-_121412805 1.315 NM_001178102
LOX
lysyl oxidase
chr20_-_20693122 1.264 NM_020343
RALGAPA2
Ral GTPase activating protein, alpha subunit 2 (catalytic)
chr4_-_114900802 1.242 NM_024590
ARSJ
arylsulfatase family, member J
chr2_-_69614321 1.234 NM_001244710
NM_002056
GFPT1

glutamine--fructose-6-phosphate transaminase 1

chr21_-_36421586 1.155 NM_001754
RUNX1
runt-related transcription factor 1
chr7_-_131241321 1.101 NM_001018111
NM_005397
PODXL

podocalyxin-like

chr8_-_119964059 1.097 NM_002546
TNFRSF11B
tumor necrosis factor receptor superfamily, member 11b
chr1_+_90286469 1.090 NM_001134479
LRRC8D
leucine rich repeat containing 8 family, member D
chr11_+_118307072 1.076 NM_001197104
NM_005933
MLL

myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila)

chr16_+_50776012 1.054 NM_001042412
CYLD
cylindromatosis (turban tumor syndrome)
chr16_+_50775960 1.051 NM_001042355
NM_015247
CYLD

cylindromatosis (turban tumor syndrome)

chr12_+_64238511 1.043 NM_020762
SRGAP1
SLIT-ROBO Rho GTPase activating protein 1
chrX_+_9432980 1.005 NM_005647
TBL1X
transducin (beta)-like 1X-linked
chr1_+_90287404 0.961 NM_018103
LRRC8D
leucine rich repeat containing 8 family, member D
chr15_+_100106132 0.957 NM_001130926
NM_001130927
NM_001171894
NM_005587
MEF2A



myocyte enhancer factor 2A



chr6_-_154831704 0.935 NM_173515
CNKSR3
CNKSR family member 3
chr11_-_128457452 0.893 NM_001143820
ETS1
v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)
chr5_+_173315313 0.892 NM_030627
CPEB4
cytoplasmic polyadenylation element binding protein 4
chr3_-_192635933 0.864 NM_178496
MB21D2
Mab-21 domain containing 2
chr15_+_100173182 0.836 NM_001130928
MEF2A
myocyte enhancer factor 2A
chr4_+_55095263 0.800 NM_006206
PDGFRA
platelet-derived growth factor receptor, alpha polypeptide
chrX_+_9431314 0.798 NM_001139466
NM_001139467
NM_001139468
TBL1X


transducin (beta)-like 1X-linked


chr22_+_46546498 0.796 NM_001001928
NM_005036
PPARA

peroxisome proliferator-activated receptor alpha

chr11_-_128392061 0.794 NM_001162422
NM_005238
ETS1

v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)

chr15_+_79724857 0.787 NM_015206
KIAA1024
KIAA1024
chr2_-_7005764 0.768 NM_207315
CMPK2
cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial
chr10_+_98592658 0.748 NM_032440
LCOR
ligand dependent nuclear receptor corepressor
chr7_-_139477437 0.746 NM_001113239
NM_022740
HIPK2

homeodomain interacting protein kinase 2

chr3_-_98620452 0.745 NM_080927
DCBLD2
discoidin, CUB and LCCL domain containing 2
chr1_-_120612301 0.743 NM_001200001
NM_024408
NOTCH2

notch 2

chr3_-_142166782 0.742 NM_001042604
NM_019001
XRN1

5'-3' exoribonuclease 1

chr14_+_55221505 0.735 NM_001161577
SAMD4A
sterile alpha motif domain containing 4A
chr12_+_26126687 0.734 NM_001164747
RASSF8
Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
chr20_-_35580186 0.732 NM_015474
SAMHD1
SAM domain and HD domain 1
chr14_+_55034329 0.731 NM_001161576
NM_015589
SAMD4A

sterile alpha motif domain containing 4A

chr17_-_49198084 0.730 NM_001130527
NM_001130528
NM_003971
SPAG9


sperm associated antigen 9


chr3_-_69101236 0.730 NM_007114
TMF1
TATA element modulatory factor 1
chr12_+_26205490 0.730 NM_001164746
RASSF8
Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
chr4_+_48343502 0.722 NM_020846
SLAIN2
SLAIN motif family, member 2
chr4_-_185747183 0.698 NM_001995
ACSL1
acyl-CoA synthetase long-chain family member 1
chr4_+_77870864 0.694 NM_018243
SEPT11
septin 11
chr10_+_98592015 0.692 NM_001170765
NM_001170766
LCOR

ligand dependent nuclear receptor corepressor

chr12_-_88974094 0.688 NM_000899
NM_003994
KITLG

KIT ligand

chr4_+_25235651 0.656 NM_018323
PI4K2B
phosphatidylinositol 4-kinase type 2 beta
chr12_+_69004614 0.652 NM_001010942
NM_001251917
NM_001251918
NM_001251921
NM_001251922
NM_015646
RAP1B





RAP1B, member of RAS oncogene family





chr2_+_64681270 0.650 NM_014181
LGALSL
lectin, galactoside-binding-like
chr9_-_15250113 0.641 NM_001168342
TTC39B
tetratricopeptide repeat domain 39B
chr3_-_113465101 0.629 NM_025146
NAA50
N(alpha)-acetyltransferase 50, NatE catalytic subunit
chr3_+_63850181 0.628 NM_000333
ATXN7
ataxin 7
chr9_-_15307325 0.625 NM_001168339
NM_001168340
NM_001168341
NM_152574
TTC39B



tetratricopeptide repeat domain 39B



chr5_-_32313069 0.622 NM_001040446
MTMR12
myotubularin related protein 12
chr2_+_112812799 0.619 NM_032824
TMEM87B
transmembrane protein 87B
chr22_-_30642683 0.619 NM_002309
LIF
leukemia inhibitory factor (cholinergic differentiation factor)
chr1_+_26737232 0.602 NM_024674
LIN28A
lin-28 homolog A (C. elegans)
chrX_+_122993536 0.601 NM_001204401
NM_001167
XIAP

X-linked inhibitor of apoptosis

chr7_-_80548666 0.596 NM_006379
SEMA3C
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr5_-_172756505 0.585 NM_003714
STC2
stanniocalcin 2
chr2_+_26568900 0.580 NM_033505
EPT1
ethanolaminephosphotransferase 1 (CDP-ethanolamine-specific)
chr5_-_95748688 0.580 NM_001177876
PCSK1
proprotein convertase subtilisin/kexin type 1
chr16_+_2587951 0.574 NM_002613
NM_031268
PDPK1

3-phosphoinositide dependent protein kinase-1

chr4_-_170924911 0.571 NM_001009554
MFAP3L
microfibrillar-associated protein 3-like
chr4_+_39046198 0.565 NM_001007075
NM_001171654
KLHL5

kelch-like 5 (Drosophila)

chr16_+_11762235 0.564 NM_003498
SNN
stannin
chr6_+_114178516 0.558 NM_002356
MARCKS
myristoylated alanine-rich protein kinase C substrate
chr2_+_102314162 0.556 NM_001242560
NM_004834
NM_145686
NM_001242559
NM_145687
MAP4K4




mitogen-activated protein kinase kinase kinase kinase 4




chr6_+_106534188 0.554 NM_001198
PRDM1
PR domain containing 1, with ZNF domain
chr12_-_16759531 0.548 NM_018640
LMO3
LIM domain only 3 (rhombotin-like 2)
chr1_+_213224530 0.541 NM_001136138
NM_012424
RPS6KC1

ribosomal protein S6 kinase, 52kDa, polypeptide 1

chr3_+_63884074 0.541 NM_001177387
ATXN7
ataxin 7
chr1_+_50571963 0.538 NM_001144775
ELAVL4
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr5_-_95768660 0.537 NM_000439
PCSK1
proprotein convertase subtilisin/kexin type 1
chr6_+_4890225 0.533 NM_001143971
CDYL
chromodomain protein, Y-like
chr1_+_50574589 0.531 NM_001144774
NM_021952
ELAVL4

ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)

chr1_+_182992329 0.531 NM_002293
LAMC1
laminin, gamma 1 (formerly LAMB2)
chr6_+_4776641 0.530 NM_004824
CDYL
chromodomain protein, Y-like
chr16_+_50186809 0.528 NM_001040284
NM_001040285
PAPD5

PAP associated domain containing 5

chr5_-_95767862 0.528 NM_001177875
PCSK1
proprotein convertase subtilisin/kexin type 1
chr3_-_122233781 0.527 NM_002264
KPNA1
karyopherin alpha 1 (importin alpha 5)
chr6_+_4836331 0.515 NM_001143970
CDYL
chromodomain protein, Y-like
chr2_-_74692534 0.513 NM_001146158
NM_006302
MOGS

mannosyl-oligosaccharide glucosidase

chr5_+_72112417 0.511 NM_002270
TNPO1
transportin 1
chr15_-_41408329 0.509 NM_017553
INO80
INO80 homolog (S. cerevisiae)
chr12_-_77459198 0.507 NM_203394
E2F7
E2F transcription factor 7
chr6_+_117996616 0.506 NM_138459
NUS1
nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae)
chr5_+_156887026 0.505 NM_001099287
NM_001172292
NIPAL4

NIPA-like domain containing 4

chr13_-_30169795 0.504 NM_003045
SLC7A1
solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
chr1_+_171454636 0.503 NM_015172
PRRC2C
proline-rich coiled-coil 2C
chr1_-_51787881 0.502 NM_001080494
TTC39A
tetratricopeptide repeat domain 39A
chr10_-_60027630 0.500 NM_152230
IPMK
inositol polyphosphate multikinase
chr8_+_11141983 0.498 NM_015458
MTMR9
myotubularin related protein 9
chr3_+_63953419 0.491 NM_001128149
ATXN7
ataxin 7
chr1_-_197169635 0.491 NM_194314
ZBTB41
zinc finger and BTB domain containing 41
chr3_-_179169330 0.488 NM_021629
GNB4
guanine nucleotide binding protein (G protein), beta polypeptide 4
chr1_-_57045235 0.483 NM_003713
PPAP2B
phosphatidic acid phosphatase type 2B
chr6_-_90062610 0.481 NM_016021
UBE2J1
ubiquitin-conjugating enzyme E2, J1, U
chr1_-_51810693 0.480 NM_001144832
TTC39A
tetratricopeptide repeat domain 39A
chr12_-_101801499 0.478 NM_001177
ARL1
ADP-ribosylation factor-like 1
chr1_+_167298280 0.472 NM_001198783
POU2F1
POU class 2 homeobox 1
chr4_+_39063851 0.472 NM_015990
NM_199039
KLHL5

kelch-like 5 (Drosophila)

chr3_-_71632741 0.468 NM_001244808
NM_001012505
NM_001244810
NM_032682
FOXP1



forkhead box P1



chr2_+_23608297 0.458 NM_052920
KLHL29
kelch-like 29 (Drosophila)
chr12_-_16760935 0.458 NM_001001395
NM_001243609
LMO3

LIM domain only 3 (rhombotin-like 2)

chr3_+_53195214 0.453 NM_006254
NM_212539
PRKCD

protein kinase C, delta

chr1_-_205912546 0.448 NM_052934
NM_134325
SLC26A9

solute carrier family 26, member 9

chr12_+_62654120 0.448 NM_001252078
NM_001252079
NM_006313
USP15


ubiquitin specific peptidase 15


chr16_-_3285359 0.447 NM_001145448
NM_198088
NM_001145446
NM_198087
ZNF200



zinc finger protein 200



chr2_-_145277879 0.444 NM_001171653
NM_014795
ZEB2

zinc finger E-box binding homeobox 2

chr3_+_42132707 0.443 NM_001042646
TRAK1
trafficking protein, kinesin binding 1
chr7_+_6144504 0.442 NM_032172
USP42
ubiquitin specific peptidase 42
chr5_+_65017993 0.438 NM_020726
NLN
neurolysin (metallopeptidase M3 family)
chr2_+_111878450 0.437 NM_001204106
NM_001204107
NM_001204108
NM_001204109
NM_001204110
NM_001204111
NM_001204112
NM_001204113
NM_006538
NM_138621
NM_138622
NM_138623
NM_138624
NM_138625
NM_138626
NM_138627
NM_207002
NM_207003
BCL2L11

















BCL2-like 11 (apoptosis facilitator)

















chr16_-_1429612 0.435 NM_001193389
NM_023076
UNKL

unkempt homolog (Drosophila)-like

chr14_+_74111577 0.434 NM_001201366
NM_031427
DNAL1

dynein, axonemal, light chain 1

chr19_-_16683188 0.433 NM_024881
SLC35E1
solute carrier family 35, member E1
chr11_-_16424391 0.433 NM_001145819
NM_017508
SOX6

SRY (sex determining region Y)-box 6

chr15_+_45879416 0.431 NM_012388
PLDN
pallidin homolog (mouse)
chr5_+_72143929 0.428 NM_153188
TNPO1
transportin 1
chr3_-_160283361 0.427 NM_002268
KPNA4
karyopherin alpha 4 (importin alpha 3)
chr21_-_36260972 0.424 NM_001001890
NM_001122607
RUNX1

runt-related transcription factor 1

chr8_-_74791098 0.423 NM_001001481
NM_018299
UBE2W

ubiquitin-conjugating enzyme E2W (putative)

chr2_-_224702300 0.422 NM_001039569
AP1S3
adaptor-related protein complex 1, sigma 3 subunit
chr11_-_85780105 0.419 NM_001008660
NM_001206946
NM_007166
PICALM


phosphatidylinositol binding clathrin assembly protein


chr1_+_50569581 0.418 NM_001144776
ELAVL4
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr14_+_70078309 0.418 NM_014734
KIAA0247
KIAA0247
chr15_+_66679107 0.413 NM_002755
MAP2K1
mitogen-activated protein kinase kinase 1
chrX_+_136648313 0.411 NM_003413
ZIC3
Zic family member 3
chr17_+_27717942 0.410 NM_020791
NM_025142
TAOK1

TAO kinase 1

chr12_-_24715349 0.408 NM_152989
SOX5
SRY (sex determining region Y)-box 5
chr10_-_120514669 0.408 NM_153810
C10orf46
chromosome 10 open reading frame 46
chr5_+_71403040 0.402 NM_005909
MAP1B
microtubule-associated protein 1B
chr12_-_48499415 0.400 NM_014554
SENP1
SUMO1/sentrin specific peptidase 1
chr17_+_26662547 0.399 NM_021137
TNFAIP1
tumor necrosis factor, alpha-induced protein 1 (endothelial)
chr18_+_55102777 0.389 NM_004852
ONECUT2
one cut homeobox 2
chr3_+_171757413 0.389 NM_022763
FNDC3B
fibronectin type III domain containing 3B
chr14_+_32798478 0.388 NM_004274
AKAP6
A kinase (PRKA) anchor protein 6
chr12_-_57030083 0.388 NM_013449
BAZ2A
bromodomain adjacent to zinc finger domain, 2A
chr15_-_65670325 0.384 NM_004884
IGDCC3
immunoglobulin superfamily, DCC subclass, member 3
chr20_+_37101457 0.384 NM_020336
RALGAPB
Ral GTPase activating protein, beta subunit (non-catalytic)
chr12_-_89918531 0.383 NM_003774
GALNT4
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 4 (GalNAc-T4)
chr10_+_102732285 0.381 NM_001203244
NM_017893
SEMA4G

sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G

chr6_+_138483024 0.380 NM_020340
KIAA1244
KIAA1244
chr1_+_50513685 0.375 NM_001144777
ELAVL4
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr4_-_41750936 0.370 NM_003924
PHOX2B
paired-like homeobox 2b
chr12_+_108523464 0.369 NM_014653
WSCD2
WSC domain containing 2
chr15_-_40401041 0.368 NM_001003940
BMF
Bcl2 modifying factor
chr12_-_56652118 0.367 NM_173595
ANKRD52
ankyrin repeat domain 52
chr6_+_106546736 0.363 NM_182907
PRDM1
PR domain containing 1, with ZNF domain
chr2_-_225450105 0.362 NM_003590
CUL3
cullin 3
chr5_+_34929679 0.361 NM_001012339
NM_194283
DNAJC21

DnaJ (Hsp40) homolog, subfamily C, member 21

chr2_+_36583369 0.358 NM_016441
CRIM1
cysteine rich transmembrane BMP regulator 1 (chordin-like)
chr3_+_88188261 0.356 NM_018293
ZNF654
zinc finger protein 654
chr4_+_7045142 0.355 NM_152293
TADA2B
transcriptional adaptor 2B
chr15_+_63481713 0.354 NM_016530
RAB8B
RAB8B, member RAS oncogene family
chr13_+_96329392 0.351 NM_006260
DNAJC3
DnaJ (Hsp40) homolog, subfamily C, member 3
chr10_+_134351272 0.348 NM_005539
INPP5A
inositol polyphosphate-5-phosphatase, 40kDa
chr2_-_197457250 0.346 NM_020760
HECW2
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2
chr19_+_40697516 0.344 NM_002446
MAP3K10
mitogen-activated protein kinase kinase kinase 10
chr7_+_97736118 0.344 NM_014916
LMTK2
lemur tyrosine kinase 2
chr3_-_11623829 0.340 NM_001128220
VGLL4
vestigial like 4 (Drosophila)
chr5_-_142783975 0.339 NM_001018076
NR3C1
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr4_-_76555570 0.339 NM_003948
CDKL2
cyclin-dependent kinase-like 2 (CDC2-related kinase)
chr16_+_20911556 0.338 NM_020424
LYRM1
LYR motif containing 1
chr3_-_50540853 0.338 NM_001005505
NM_001174051
NM_006030
CACNA2D2


calcium channel, voltage-dependent, alpha 2/delta subunit 2


chr2_-_206950895 0.337 NM_017759
INO80D
INO80 complex subunit D
chr7_+_103969103 0.337 NM_199000
LHFPL3
lipoma HMGIC fusion partner-like 3
chr11_+_32914359 0.334 NM_001076786
QSER1
glutamine and serine rich 1
chr6_+_34759743 0.334 NM_017754
UHRF1BP1
UHRF1 binding protein 1
chr16_+_20911987 0.333 NM_001128301
NM_001128302
LYRM1

LYR motif containing 1

chr4_-_170947428 0.332 NM_021647
MFAP3L
microfibrillar-associated protein 3-like
chr11_+_10326618 0.331 NM_001124
ADM
adrenomedullin
chr8_-_124054591 0.329 NM_001134671
NM_024295
DERL1

Der1-like domain family, member 1

chr2_-_225907312 0.329 NM_014689
DOCK10
dedicator of cytokinesis 10
chr12_+_12764755 0.327 NM_001310
CREBL2
cAMP responsive element binding protein-like 2
chr11_-_85780899 0.325 NM_001206947
PICALM
phosphatidylinositol binding clathrin assembly protein
chr2_-_201936389 0.324 NM_173822
FAM126B
family with sequence similarity 126, member B
chr16_-_3285069 0.323 NM_001145447
NM_003454
ZNF200

zinc finger protein 200

chr9_+_101867401 0.322 NM_001130916
NM_004612
TGFBR1

transforming growth factor, beta receptor 1

chr2_-_113542970 0.320 NM_000575
IL1A
interleukin 1, alpha
chr12_-_498428 0.320 NM_001042603
KDM5A
lysine (K)-specific demethylase 5A
chr6_+_43211221 0.318 NM_032538
TTBK1
tau tubulin kinase 1
chr15_-_40398573 0.316 NM_033503
BMF
Bcl2 modifying factor
chr12_+_26111951 0.313 NM_001164748
NM_007211
RASSF8

Ras association (RalGDS/AF-6) domain family (N-terminal) member 8

chr14_-_61190458 0.313 NM_017420
SIX4
SIX homeobox 4
chr20_+_32150139 0.313 NM_001039709
NM_005093
CBFA2T2

core-binding factor, runt domain, alpha subunit 2; translocated to, 2

chr8_+_61591239 0.311 NM_017780
CHD7
chromodomain helicase DNA binding protein 7
chr17_-_4167028 0.311 NM_016376
NM_020740
ANKFY1

ankyrin repeat and FYVE domain containing 1

chr7_+_18126543 0.308 NM_001204144
HDAC9
histone deacetylase 9
chr3_-_11610264 0.308 NM_001128221
VGLL4
vestigial like 4 (Drosophila)
chr5_-_158634641 0.305 NM_001199382
RNF145
ring finger protein 145

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.57 3.62e-09 GO:0031323 regulation of cellular metabolic process
1.34 4.25e-09 GO:0050794 regulation of cellular process
1.54 6.83e-08 GO:0080090 regulation of primary metabolic process
1.30 1.34e-07 GO:0050789 regulation of biological process
1.44 5.13e-07 GO:0044260 cellular macromolecule metabolic process
1.76 1.12e-06 GO:0006464 protein modification process
1.27 1.21e-06 GO:0065007 biological regulation
1.52 1.24e-06 GO:0060255 regulation of macromolecule metabolic process
1.45 3.63e-06 GO:0019222 regulation of metabolic process
1.58 7.22e-06 GO:0010468 regulation of gene expression
1.59 1.02e-05 GO:0010556 regulation of macromolecule biosynthetic process
1.60 1.03e-05 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.56 1.43e-05 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.56 1.43e-05 GO:0031326 regulation of cellular biosynthetic process
1.61 1.76e-05 GO:0051252 regulation of RNA metabolic process
1.55 1.76e-05 GO:0009889 regulation of biosynthetic process
2.42 2.18e-05 GO:0044265 cellular macromolecule catabolic process
1.67 2.60e-05 GO:0043412 macromolecule modification
1.61 3.33e-05 GO:0006355 regulation of transcription, DNA-dependent
1.52 6.37e-05 GO:0051171 regulation of nitrogen compound metabolic process
1.35 7.54e-05 GO:0043170 macromolecule metabolic process
2.22 1.45e-04 GO:0009057 macromolecule catabolic process
1.58 4.88e-04 GO:0030154 cell differentiation
1.56 6.90e-04 GO:0048869 cellular developmental process
1.50 8.26e-04 GO:0044267 cellular protein metabolic process
1.55 8.83e-04 GO:0048523 negative regulation of cellular process
1.68 9.69e-04 GO:0009653 anatomical structure morphogenesis
2.01 1.29e-03 GO:0006468 protein phosphorylation
2.55 1.79e-03 GO:0051603 proteolysis involved in cellular protein catabolic process
2.59 1.85e-03 GO:0006511 ubiquitin-dependent protein catabolic process
2.03 1.91e-03 GO:0009790 embryo development
2.54 2.07e-03 GO:0070647 protein modification by small protein conjugation or removal
5.51 2.40e-03 GO:0070646 protein modification by small protein removal
1.81 2.75e-03 GO:0006793 phosphorus metabolic process
1.81 2.75e-03 GO:0006796 phosphate metabolic process
2.50 2.75e-03 GO:0044257 cellular protein catabolic process
2.54 2.88e-03 GO:0019941 modification-dependent protein catabolic process
1.49 3.08e-03 GO:0048519 negative regulation of biological process
1.90 3.27e-03 GO:0016310 phosphorylation
2.52 3.33e-03 GO:0043632 modification-dependent macromolecule catabolic process
2.41 4.47e-03 GO:0030163 protein catabolic process
1.25 4.80e-03 GO:0044238 primary metabolic process
1.40 5.18e-03 GO:0048856 anatomical structure development
1.25 5.33e-03 GO:0044237 cellular metabolic process
2.39 5.44e-03 GO:0043009 chordate embryonic development
2.36 7.05e-03 GO:0009792 embryo development ending in birth or egg hatching
2.08 1.12e-02 GO:0051253 negative regulation of RNA metabolic process
2.02 1.14e-02 GO:0010629 negative regulation of gene expression
1.34 1.17e-02 GO:0032502 developmental process
1.99 1.27e-02 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
2.07 1.56e-02 GO:0045892 negative regulation of transcription, DNA-dependent
1.59 2.22e-02 GO:0007399 nervous system development
1.74 2.58e-02 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.90 2.71e-02 GO:0031327 negative regulation of cellular biosynthetic process
1.90 4.08e-02 GO:0010558 negative regulation of macromolecule biosynthetic process
1.75 4.20e-02 GO:0010605 negative regulation of macromolecule metabolic process
1.75 4.20e-02 GO:0022008 neurogenesis
2.37 4.63e-02 GO:0045860 positive regulation of protein kinase activity
1.87 4.69e-02 GO:0009890 negative regulation of biosynthetic process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.32 4.91e-06 GO:0005634 nucleus
1.13 1.96e-04 GO:0005622 intracellular
1.14 2.08e-04 GO:0044424 intracellular part
1.17 3.56e-03 GO:0043231 intracellular membrane-bounded organelle
1.17 4.05e-03 GO:0043227 membrane-bounded organelle
2.85 4.78e-03 GO:0030424 axon
1.14 1.53e-02 GO:0043226 organelle
1.14 1.70e-02 GO:0043229 intracellular organelle

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.33 2.99e-10 GO:0005515 protein binding
1.17 2.22e-09 GO:0005488 binding
1.63 4.25e-06 GO:0008270 zinc ion binding
1.83 1.94e-04 GO:0030528 transcription regulator activity
1.49 4.79e-04 GO:0046914 transition metal ion binding
1.75 2.46e-03 GO:0001071 nucleic acid binding transcription factor activity
1.75 2.46e-03 GO:0003700 sequence-specific DNA binding transcription factor activity
2.17 3.30e-03 GO:0004674 protein serine/threonine kinase activity
1.87 3.84e-03 GO:0016773 phosphotransferase activity, alcohol group as acceptor
1.35 5.21e-03 GO:0003676 nucleic acid binding
1.80 7.19e-03 GO:0016301 kinase activity
1.43 7.81e-03 GO:0003677 DNA binding
1.73 9.92e-03 GO:0016772 transferase activity, transferring phosphorus-containing groups
5.51 1.16e-02 GO:0019783 small conjugating protein-specific protease activity
1.89 1.30e-02 GO:0004672 protein kinase activity
1.30 1.56e-02 GO:0046872 metal ion binding
2.43 1.90e-02 GO:0003702 RNA polymerase II transcription factor activity
1.28 3.08e-02 GO:0043169 cation binding
1.28 3.56e-02 GO:0043167 ion binding
3.72 3.64e-02 GO:0003729 mRNA binding
4.78 3.88e-02 GO:0046332 SMAD binding