Motif ID: ACAUUCA

Z-value: 1.016


Mature miRNA associated with seed ACAUUCA:

NamemiRBase Accession
hsa-miR-181a MIMAT0000256
hsa-miR-181b MIMAT0000257
hsa-miR-181c MIMAT0000258
hsa-miR-181d MIMAT0002821
hsa-miR-4262 MIMAT0016894



Activity profile for motif ACAUUCA.

activity profile for motif ACAUUCA


Sorted Z-values histogram for motif ACAUUCA

Sorted Z-values for motif ACAUUCA



Network of associatons between targets according to the STRING database.



First level regulatory network of ACAUUCA

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr4_-_120549115 2.765 NM_033437
PDE5A
phosphodiesterase 5A, cGMP-specific
chr7_-_25019625 2.589 NM_015550
NM_145320
NM_145321
NM_145322
OSBPL3



oxysterol binding protein-like 3



chr7_-_47621741 2.555 NM_022748
TNS3
tensin 3
chr4_-_120549827 2.118 NM_001083
PDE5A
phosphodiesterase 5A, cGMP-specific
chr8_+_23386362 1.806 NM_016612
SLC25A37
solute carrier family 25, member 37
chr11_-_125933186 1.757 NM_001243597
NM_016952
CDON

Cdon homolog (mouse)

chr9_+_72658496 1.730 NM_153267
MAMDC2
MAM domain containing 2
chr4_-_120548329 1.699 NM_033430
PDE5A
phosphodiesterase 5A, cGMP-specific
chr5_-_141704575 1.620 NM_001127496
NM_030964
SPRY4

sprouty homolog 4 (Drosophila)

chr1_+_169075869 1.402 NM_001677
ATP1B1
ATPase, Na+/K+ transporting, beta 1 polypeptide
chr5_-_121414011 1.337 NM_002317
LOX
lysyl oxidase
chr5_-_121412805 1.315 NM_001178102
LOX
lysyl oxidase
chr20_-_20693122 1.264 NM_020343
RALGAPA2
Ral GTPase activating protein, alpha subunit 2 (catalytic)
chr4_-_114900802 1.242 NM_024590
ARSJ
arylsulfatase family, member J
chr2_-_69614321 1.234 NM_001244710
NM_002056
GFPT1

glutamine--fructose-6-phosphate transaminase 1

chr21_-_36421586 1.155 NM_001754
RUNX1
runt-related transcription factor 1
chr7_-_131241321 1.101 NM_001018111
NM_005397
PODXL

podocalyxin-like

chr8_-_119964059 1.097 NM_002546
TNFRSF11B
tumor necrosis factor receptor superfamily, member 11b
chr1_+_90286469 1.090 NM_001134479
LRRC8D
leucine rich repeat containing 8 family, member D
chr11_+_118307072 1.076 NM_001197104
NM_005933
MLL

myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila)


Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 59 entries
enrichment   p-value GO term description
5.51 2.40e-03 GO:0070646 protein modification by small protein removal
2.59 1.85e-03 GO:0006511 ubiquitin-dependent protein catabolic process
2.55 1.79e-03 GO:0051603 proteolysis involved in cellular protein catabolic process
2.54 2.07e-03 GO:0070647 protein modification by small protein conjugation or removal
2.54 2.88e-03 GO:0019941 modification-dependent protein catabolic process
2.52 3.33e-03 GO:0043632 modification-dependent macromolecule catabolic process
2.50 2.75e-03 GO:0044257 cellular protein catabolic process
2.42 2.18e-05 GO:0044265 cellular macromolecule catabolic process
2.41 4.47e-03 GO:0030163 protein catabolic process
2.39 5.44e-03 GO:0043009 chordate embryonic development
2.37 4.63e-02 GO:0045860 positive regulation of protein kinase activity
2.36 7.05e-03 GO:0009792 embryo development ending in birth or egg hatching
2.22 1.45e-04 GO:0009057 macromolecule catabolic process
2.08 1.12e-02 GO:0051253 negative regulation of RNA metabolic process
2.07 1.56e-02 GO:0045892 negative regulation of transcription, DNA-dependent
2.03 1.91e-03 GO:0009790 embryo development
2.02 1.14e-02 GO:0010629 negative regulation of gene expression
2.01 1.29e-03 GO:0006468 protein phosphorylation
1.99 1.27e-02 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
1.90 3.27e-03 GO:0016310 phosphorylation

Gene overrepresentation in compartment category:

Showing 1 to 8 of 8 entries
enrichment   p-value GO term description
2.85 4.78e-03 GO:0030424 axon
1.32 4.91e-06 GO:0005634 nucleus
1.17 3.56e-03 GO:0043231 intracellular membrane-bounded organelle
1.17 4.05e-03 GO:0043227 membrane-bounded organelle
1.14 2.08e-04 GO:0044424 intracellular part
1.14 1.53e-02 GO:0043226 organelle
1.14 1.70e-02 GO:0043229 intracellular organelle
1.13 1.96e-04 GO:0005622 intracellular

Gene overrepresentation in function category:

Showing 1 to 20 of 21 entries
enrichment   p-value GO term description
5.51 1.16e-02 GO:0019783 small conjugating protein-specific protease activity
4.78 3.88e-02 GO:0046332 SMAD binding
3.72 3.64e-02 GO:0003729 mRNA binding
2.43 1.90e-02 GO:0003702 RNA polymerase II transcription factor activity
2.17 3.30e-03 GO:0004674 protein serine/threonine kinase activity
1.89 1.30e-02 GO:0004672 protein kinase activity
1.87 3.84e-03 GO:0016773 phosphotransferase activity, alcohol group as acceptor
1.83 1.94e-04 GO:0030528 transcription regulator activity
1.80 7.19e-03 GO:0016301 kinase activity
1.75 2.46e-03 GO:0001071 nucleic acid binding transcription factor activity
1.75 2.46e-03 GO:0003700 sequence-specific DNA binding transcription factor activity
1.73 9.92e-03 GO:0016772 transferase activity, transferring phosphorus-containing groups
1.63 4.25e-06 GO:0008270 zinc ion binding
1.49 4.79e-04 GO:0046914 transition metal ion binding
1.43 7.81e-03 GO:0003677 DNA binding
1.35 5.21e-03 GO:0003676 nucleic acid binding
1.33 2.99e-10 GO:0005515 protein binding
1.30 1.56e-02 GO:0046872 metal ion binding
1.28 3.08e-02 GO:0043169 cation binding
1.28 3.56e-02 GO:0043167 ion binding