Motif ID: ADNP_IRX_SIX_ZHX.p2

Z-value: 0.999


Transcription factors associated with ADNP_IRX_SIX_ZHX.p2:

Gene SymbolEntrez IDGene Name
ADNP 23394 activity-dependent neuroprotector homeobox
IRX4 50805 iroquois homeobox 4
IRX5 10265 iroquois homeobox 5
SIX2 10736 SIX homeobox 2
SIX5 147912 SIX homeobox 5
ZHX1 11244 zinc fingers and homeoboxes 1
ZHX2 22882 zinc fingers and homeoboxes 2
ZHX3 23051 zinc fingers and homeoboxes 3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.p-valuePlot
ZHX1chr8_-_1242864890.572.7e-03Click!
ZHX3chr20_-_399287080.501.0e-02Click!
ADNPchr20_-_495474510.481.6e-02Click!
IRX5chr16_+_54965110-0.376.9e-02Click!
ZHX2chr8_+_123793988,
chr8_+_123794043
-0.262.2e-01Click!
SIX2chr2_-_45236521-0.125.6e-01Click!
IRX4chr5_-_1882764-0.096.6e-01Click!
SIX5chr19_-_46272496-0.019.5e-01Click!


Activity profile for motif ADNP_IRX_SIX_ZHX.p2.

activity profile for motif ADNP_IRX_SIX_ZHX.p2


Sorted Z-values histogram for motif ADNP_IRX_SIX_ZHX.p2

Sorted Z-values for motif ADNP_IRX_SIX_ZHX.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ADNP_IRX_SIX_ZHX.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr4_+_41614911 7.333 NM_001112719
NM_001112720
LIMCH1

LIM and calponin homology domains 1

chr4_+_41700736 6.490 LIMCH1
LIM and calponin homology domains 1
chr1_+_61869699 5.930 NFIA
nuclear factor I/A
chr9_-_14086901 5.890 NFIB
nuclear factor I/B
chr4_+_41614725 5.672 LIMCH1
LIM and calponin homology domains 1
chr1_+_84630014 4.834 NM_001242857
NM_001242858
NM_001242859
PRKACB


protein kinase, cAMP-dependent, catalytic, beta


chr4_+_41614933 4.377 LIMCH1
LIM and calponin homology domains 1
chr1_+_84630575 3.297 NM_001242860
NM_001242861
PRKACB

protein kinase, cAMP-dependent, catalytic, beta

chr1_+_84630374 2.739 PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr3_+_132316080 2.324 NM_016557
CCRL1
chemokine (C-C motif) receptor-like 1
chr10_+_5136556 2.272 NM_003739
AKR1C3
aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)
chr15_+_25281105 2.200 SNRPN
small nuclear ribonucleoprotein polypeptide N
chr10_+_5136613 2.172 AKR1C3
aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)
chr6_-_76203256 2.163 NM_015687
FILIP1
filamin A interacting protein 1
chr1_+_78470593 2.156 NM_007034
DNAJB4
DnaJ (Hsp40) homolog, subfamily B, member 4
chr9_+_2015218 2.142 NM_003070
NM_139045
SMARCA2

SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2

chr10_+_5136589 2.081 AKR1C3
aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)
chr11_-_33913835 2.044 NM_005574
LMO2
LIM domain only 2 (rhombotin-like 1)
chr12_+_20963637 2.022 NM_019844
SLCO1B3
solute carrier organic anion transporter family, member 1B3
chr5_-_111312522 1.931 NM_001142474
NM_001142475
C5orf13

chromosome 5 open reading frame 13


Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 11 of 11 entries
enrichment   p-value GO term description
9.24 2.66e-02 GO:0009812 flavonoid metabolic process
6.53 2.65e-02 GO:0042573 retinoic acid metabolic process
4.95 3.96e-02 GO:0006776 vitamin A metabolic process
4.62 3.16e-02 GO:0001523 retinoid metabolic process
4.62 3.16e-02 GO:0016101 diterpenoid metabolic process
1.80 4.18e-04 GO:0009790 embryo development
1.37 3.02e-02 GO:0048513 organ development
1.31 2.90e-04 GO:0007275 multicellular organismal development
1.28 6.75e-04 GO:0032502 developmental process
1.24 2.21e-04 GO:0032501 multicellular organismal process
1.15 3.66e-03 GO:0065007 biological regulation

Gene overrepresentation in compartment category:

Showing 1 to 1 of 1 entries
enrichment   p-value GO term description
2.23 2.53e-02 GO:0016324 apical plasma membrane

Gene overrepresentation in function category:

Showing 1 to 1 of 1 entries
enrichment   p-value GO term description
1.73 4.45e-02 GO:0008289 lipid binding