Motif ID: AGCAGCA

Z-value: 2.011


Mature miRNA associated with seed AGCAGCA:

NamemiRBase Accession
hsa-miR-15a MIMAT0000068
hsa-miR-15b MIMAT0000417
hsa-miR-16 MIMAT0000069
hsa-miR-195 MIMAT0000461
hsa-miR-424 MIMAT0001341
hsa-miR-497 MIMAT0002820



Activity profile for motif AGCAGCA.

activity profile for motif AGCAGCA


Sorted Z-values histogram for motif AGCAGCA

Sorted Z-values for motif AGCAGCA



Network of associatons between targets according to the STRING database.



First level regulatory network of AGCAGCA

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr4_-_76944585 8.895 NM_001565
 CXCL10
chemokine (C-X-C motif) ligand 10
chr11_+_69455837 6.644 NM_053056
 CCND1
cyclin D1
chr12_-_105322056 6.068 NM_032148
 SLC41A2
solute carrier family 41, member 2
chr1_+_65613771 5.414 NM_013410
 AK4
adenylate kinase 4
chr1_+_65613211 5.362 NM_203464
NM_001005353
 AK4

adenylate kinase 4

chr3_-_123603144 4.803 NM_053025
NM_053026
NM_053027
NM_053028
 MYLK



myosin light chain kinase



chr6_-_134498973 4.722 NM_001143677
 SGK1
serum/glucocorticoid regulated kinase 1
chr6_-_134639195 4.722 NM_001143676
 SGK1
serum/glucocorticoid regulated kinase 1
chr6_-_134496006 4.701 NM_005627
 SGK1
serum/glucocorticoid regulated kinase 1
chr6_-_134497069 4.652 NM_001143678
 SGK1
serum/glucocorticoid regulated kinase 1
chr3_-_123339423 4.509 NM_053031
NM_053032
 MYLK

myosin light chain kinase

chr19_-_49222956 4.219 NM_001130915
 MAMSTR
MEF2 activating motif and SAP domain containing transcriptional regulator
chr19_-_49220213 4.197 NM_182574
 MAMSTR
MEF2 activating motif and SAP domain containing transcriptional regulator
chr2_+_112812799 3.733 NM_032824
 TMEM87B
transmembrane protein 87B
chr7_-_83824216 3.602 NM_006080
 SEMA3A
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr1_-_201438150 3.349 NM_012396
 PHLDA3
pleckstrin homology-like domain, family A, member 3
chr5_+_127419407 3.298 NM_001046
 SLC12A2
solute carrier family 12 (sodium/potassium/chloride transporters), member 2
chr8_+_31497267 3.196 NM_013962
 NRG1
neuregulin 1
chr1_+_145438437 3.193 NM_006472
 TXNIP
thioredoxin interacting protein
chr22_-_42017032 2.984 NM_015704
 PPPDE2
PPPDE peptidase domain containing 2

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 51 entries
enrichment   p-value GO term description
3.04 4.63e-04 GO:0008286 insulin receptor signaling pathway
2.91 1.96e-03 GO:0016055 Wnt receptor signaling pathway
2.69 1.07e-03 GO:0032869 cellular response to insulin stimulus
2.02 1.60e-04 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
1.94 5.00e-05 GO:0007167 enzyme linked receptor protein signaling pathway
1.81 3.91e-02 GO:0031175 neuron projection development
1.76 2.72e-02 GO:0048666 neuron development
1.74 6.06e-03 GO:0019220 regulation of phosphate metabolic process
1.74 6.06e-03 GO:0051174 regulation of phosphorus metabolic process
1.74 6.42e-03 GO:0030182 neuron differentiation
1.74 1.54e-02 GO:0030030 cell projection organization
1.73 2.34e-02 GO:0001932 regulation of protein phosphorylation
1.72 1.49e-02 GO:0042325 regulation of phosphorylation
1.66 6.04e-03 GO:0048699 generation of neurons
1.64 2.26e-02 GO:0031399 regulation of protein modification process
1.62 1.14e-02 GO:0022008 neurogenesis
1.59 8.03e-03 GO:0032268 regulation of cellular protein metabolic process
1.58 6.58e-05 GO:0007399 nervous system development
1.58 1.83e-02 GO:0042127 regulation of cell proliferation
1.57 4.82e-02 GO:0048468 cell development

Gene overrepresentation in compartment category:

Showing 1 to 16 of 16 entries
enrichment   p-value GO term description
6.07 2.77e-02 GO:0000307 cyclin-dependent protein kinase holoenzyme complex
2.01 1.35e-02 GO:0005874 microtubule
1.47 7.79e-04 GO:0005856 cytoskeleton
1.33 2.95e-04 GO:0043234 protein complex
1.31 3.38e-02 GO:0044459 plasma membrane part
1.28 2.35e-02 GO:0043228 non-membrane-bounded organelle
1.28 2.35e-02 GO:0043232 intracellular non-membrane-bounded organelle
1.23 3.48e-02 GO:0032991 macromolecular complex
1.17 3.04e-02 GO:0005634 nucleus
1.14 2.14e-03 GO:0005737 cytoplasm
1.13 6.37e-07 GO:0005622 intracellular
1.12 7.52e-06 GO:0044424 intracellular part
1.12 2.30e-03 GO:0043229 intracellular organelle
1.12 3.12e-03 GO:0043226 organelle
1.05 3.99e-03 GO:0044464 cell part
1.05 4.09e-03 GO:0005623 cell

Gene overrepresentation in function category:

Showing 1 to 10 of 10 entries
enrichment   p-value GO term description
3.93 1.95e-02 GO:0046332 SMAD binding
3.08 5.71e-03 GO:0017016 Ras GTPase binding
2.92 7.76e-03 GO:0031267 small GTPase binding
2.82 5.23e-03 GO:0051020 GTPase binding
2.13 8.80e-03 GO:0005096 GTPase activator activity
1.79 1.43e-02 GO:0030695 GTPase regulator activity
1.75 2.97e-02 GO:0060589 nucleoside-triphosphatase regulator activity
1.58 3.03e-02 GO:0019899 enzyme binding
1.26 1.18e-10 GO:0005515 protein binding
1.10 2.13e-04 GO:0005488 binding