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• Mean activities

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• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)
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Motif ID: AGCAGCG

Z-value: 1.068

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr18_-_46477080	2.316	NM_001190821 NM_005904	SMAD7	SMAD family member 7
chr18_-_46475702	2.278	NM_001190822	SMAD7	SMAD family member 7
chr18_-_46469118	2.175	NM_001190823	SMAD7	SMAD family member 7
chr6_+_7107986	1.865	NM_001003698 NM_001003699 NM_001003700	RREB1	ras responsive element binding protein 1
chr9_+_504661	1.853	NM_015158	KANK1	KN motif and ankyrin repeat domains 1
chr9_+_706744	1.795	NM_153186	KANK1	KN motif and ankyrin repeat domains 1
chr6_+_7107799	1.754	NM_001168344	RREB1	ras responsive element binding protein 1
chr3_+_43328001	1.626	NM_001100594 NM_017719	SNRK	SNF related kinase
chr11_+_69455837	1.586	NM_053056	CCND1	cyclin D1
chr8_-_57123858	1.442	NM_001114634 NM_001114635 NM_002655	PLAG1	pleiomorphic adenoma gene 1
chr8_-_93115453	1.370	NM_001198633 NM_175634	RUNX1T1	runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chrX_-_108976509	1.202	NM_004458 NM_022977	ACSL4	acyl-CoA synthetase long-chain family member 4
chr8_-_93107881	1.199	NM_001198625 NM_001198626 NM_001198627 NM_001198631 NM_001198634 NM_001198679	RUNX1T1	runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr8_-_93111915	1.187	NM_001198628	RUNX1T1	runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr8_-_93107442	1.184	NM_001198629 NM_001198630 NM_001198632 NM_175635	RUNX1T1	runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr8_-_93029864	1.159	NM_175636	RUNX1T1	runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr17_+_58677489	1.156	NM_003620	PPM1D	protein phosphatase, Mg2+/Mn2+ dependent, 1D
chr6_+_18387580	1.151	NM_182757	RNF144B	ring finger protein 144B
chr12_-_8088629	1.123	NM_006931	SLC2A3	solute carrier family 2 (facilitated glucose transporter), member 3
chr8_-_93075190	1.113	NM_004349	RUNX1T1	runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr19_-_51143091	1.096	NM_001160328 NM_001160329	SYT3	synaptotagmin III
chr19_-_51141301	1.016	NM_032298	SYT3	synaptotagmin III
chr20_-_31071187	1.012	NM_080616	C20orf112	chromosome 20 open reading frame 112
chr22_+_40440664	0.990	NM_001024843	TNRC6B	trinucleotide repeat containing 6B
chr3_-_129612371	0.965	NM_001128224	TMCC1	transmembrane and coiled-coil domain family 1
chr8_-_92053043	0.951	NM_018710	TMEM55A	transmembrane protein 55A
chr13_-_67804432	0.945	NM_020403 NM_203487	PCDH9	protocadherin 9
chr16_-_20753117	0.928	NM_017736	THUMPD1	THUMP domain containing 1
chr18_-_72921280	0.926	NM_175907	ZADH2	zinc binding alcohol dehydrogenase domain containing 2
chr3_-_123603144	0.926	NM_053025 NM_053026 NM_053027 NM_053028	MYLK	myosin light chain kinase
chr6_-_134497069	0.923	NM_001143678	SGK1	serum/glucocorticoid regulated kinase 1
chr5_+_67511578	0.918	NM_181523	PIK3R1	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr1_+_65613211	0.913	NM_203464 NM_001005353	AK4	adenylate kinase 4
chr1_-_197169635	0.907	NM_194314	ZBTB41	zinc finger and BTB domain containing 41
chr15_+_47476225	0.907	NM_001198999	SEMA6D	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
chr20_-_39317875	0.904	NM_005461	MAFB	v-maf musculoaponeurotic fibrosarcoma oncogene homolog B (avian)
chr1_+_15853348	0.885	NM_015291	DNAJC16	DnaJ (Hsp40) homolog, subfamily C, member 16
chr6_-_134498973	0.876	NM_001143677	SGK1	serum/glucocorticoid regulated kinase 1
chr3_-_123339423	0.875	NM_053031 NM_053032	MYLK	myosin light chain kinase
chr16_+_53088791	0.872	NM_025134	CHD9	chromodomain helicase DNA binding protein 9
chr13_+_42846255	0.858	NM_016248	AKAP11	A kinase (PRKA) anchor protein 11
chr1_+_65613771	0.856	NM_013410	AK4	adenylate kinase 4
chr6_-_134496006	0.855	NM_005627	SGK1	serum/glucocorticoid regulated kinase 1
chr6_+_34857021	0.845	NM_015245	ANKS1A	ankyrin repeat and sterile alpha motif domain containing 1A
chr5_+_174905513	0.831	NM_022754	SFXN1	sideroflexin 1
chr19_+_30302861	0.829	NM_001238	CCNE1	cyclin E1
chrX_-_128788913	0.819	NM_017413	APLN	apelin
chr22_+_24823529	0.814	NM_000675	ADORA2A	adenosine A2a receptor
chr6_+_107811272	0.806	NM_018013	SOBP	sine oculis binding protein homolog (Drosophila)
chr6_-_134639195	0.806	NM_001143676	SGK1	serum/glucocorticoid regulated kinase 1
chr3_-_129599220	0.802	NM_001017395	TMCC1	transmembrane and coiled-coil domain family 1
chr12_-_56615484	0.798	NM_001242826	RNF41	ring finger protein 41
chr6_+_71123105	0.796	NM_001105531 NM_020819	FAM135A	family with sequence similarity 135, member A
chr5_+_67586466	0.768	NM_181504	PIK3R1	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr6_+_11538486	0.768	NM_001100829	TMEM170B	transmembrane protein 170B
chr2_+_113033146	0.751	NM_198581	ZC3H6	zinc finger CCCH-type containing 6
chr5_+_139493689	0.734	NM_005859	PURA	purine-rich element binding protein A
chr15_+_48010685	0.734	NM_020858 NM_024966 NM_153616 NM_153617 NM_153618 NM_153619	SEMA6D	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
chr5_+_67584251	0.720	NM_181524	PIK3R1	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr12_-_56615679	0.713	NM_005785 NM_194358 NM_194359	RNF41	ring finger protein 41
chr1_+_162466963	0.711	NM_001184763	UHMK1	U2AF homology motif (UHM) kinase 1
chr6_+_71136141	0.696	NM_001162529	FAM135A	family with sequence similarity 135, member A
chr1_+_162467594	0.692	NM_144624 NM_175866	UHMK1	U2AF homology motif (UHM) kinase 1
chr13_+_108921976	0.687	NM_001145645 NM_006573	TNFSF13B	tumor necrosis factor (ligand) superfamily, member 13b
chr11_+_9596233	0.686	NM_001143976	WEE1	WEE1 homolog (S. pombe)
chr4_-_69215699	0.678	NM_001031732 NM_133370	YTHDC1	YTH domain containing 1
chr17_-_62658311	0.677	NM_022739	SMURF2	SMAD specific E3 ubiquitin protein ligase 2
chr17_+_30813928	0.662	NM_003885	CDK5R1	cyclin-dependent kinase 5, regulatory subunit 1 (p35)
chr17_+_7761063	0.652	NM_144607	CYB5D1	cytochrome b5 domain containing 1
chr3_-_178789597	0.643	NM_022470 NM_152240	ZMAT3	zinc finger, matrin-type 3
chr9_+_71394919	0.610	NM_138333	FAM122A	family with sequence similarity 122A
chr5_+_67588395	0.608	NM_001242466	PIK3R1	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr22_+_40573879	0.604	NM_001162501 NM_015088	TNRC6B	trinucleotide repeat containing 6B
chr12_+_57943843	0.601	NM_004984	KIF5A	kinesin family member 5A
chr9_-_99180661	0.600	NM_153695	ZNF367	zinc finger protein 367
chr17_-_65241305	0.598	NM_014877	HELZ	helicase with zinc finger
chr14_+_53196852	0.596	NM_001130701 NM_145251	STYX	serine/threonine/tyrosine interacting protein
chr7_+_90032647	0.591	NM_001185072 NM_001185073 NM_012129	CLDN12	claudin 12
chr12_-_118406027	0.584	NM_173598	KSR2	kinase suppressor of ras 2
chr9_+_37800779	0.577	NM_024345	DCAF10	DDB1 and CUL4 associated factor 10
chr17_+_65821625	0.574	NM_004459 NM_182641	BPTF	bromodomain PHD finger transcription factor
chr1_+_201617449	0.573	NM_020443	NAV1	neuron navigator 1
chr2_+_148602569	0.569	NM_001616	ACVR2A	activin A receptor, type IIA
chr19_+_1248548	0.565	NM_177401	MIDN	midnolin
chr4_+_166128769	0.564	NM_007246	KLHL2	kelch-like 2, Mayven (Drosophila)
chr9_-_127905715	0.564	NM_001144877 NM_173690	SCAI	suppressor of cancer cell invasion
chr4_+_166131170	0.561	NM_001161521 NM_001161522	KLHL2	kelch-like 2, Mayven (Drosophila)
chr12_+_4382882	0.554	NM_001759	CCND2	cyclin D2
chr15_+_38544966	0.551	NM_152594	SPRED1	sprouty-related, EVH1 domain containing 1
chr19_+_18747827	0.550	NM_018316	KLHL26	kelch-like 26 (Drosophila)
chr14_-_39901619	0.548	NM_203301	FBXO33	F-box protein 33
chr4_-_99851785	0.544	NM_001130679 NM_001968	EIF4E	eukaryotic translation initiation factor 4E
chr16_+_18995508	0.537	NM_001160364	TMC7	transmembrane channel-like 7
chr11_+_9595183	0.534	NM_003390	WEE1	WEE1 homolog (S. pombe)
chr18_-_61034350	0.531	NM_002035	KDSR	3-ketodihydrosphingosine reductase
chrX_-_103087106	0.530	NM_016370	RAB9B	RAB9B, member RAS oncogene family
chr3_+_150126705	0.510	NM_014779	TSC22D2	TSC22 domain family, member 2
chr8_-_42397048	0.507	NM_006749	SLC20A2	solute carrier family 20 (phosphate transporter), member 2
chr1_-_36915969	0.500	NM_145047 NM_206837	OSCP1	organic solute carrier partner 1
chr1_+_201708940	0.498	NM_001167738	NAV1	neuron navigator 1
chr4_+_15004297	0.478	NM_001177381 NM_001177382 NM_001177383 NM_001177384 NM_182485 NM_182646	CPEB2	cytoplasmic polyadenylation element binding protein 2
chr16_+_18995255	0.471	NM_024847	TMC7	transmembrane channel-like 7
chr14_+_31028328	0.469	NM_017769	G2E3	G2/M-phase specific E3 ubiquitin protein ligase
chr5_+_172068188	0.464	NM_001142651	NEURL1B	neuralized homolog 1B (Drosophila)
chr4_-_99850242	0.461	NM_001130678	EIF4E	eukaryotic translation initiation factor 4E
chr1_+_47799447	0.460	NM_001136140 NM_016308	CMPK1	cytidine monophosphate (UMP-CMP) kinase 1, cytosolic
chr6_-_80247103	0.460	NM_001122769 NM_181714	LCA5	Leber congenital amaurosis 5
chr18_+_29672568	0.459	NM_001191324 NM_198128	RNF138	ring finger protein 138
chr4_-_153456152	0.439	NM_033632	FBXW7	F-box and WD repeat domain containing 7
chr12_-_63328663	0.435	NM_020700	PPM1H	protein phosphatase, Mg2+/Mn2+ dependent, 1H
chr16_+_58549382	0.435	NM_001160305 NM_024860	SETD6	SET domain containing 6
chr17_+_5031686	0.434	NM_004505	USP6	ubiquitin specific peptidase 6 (Tre-2 oncogene)
chr2_-_99347588	0.433	NM_012214	MGAT4A	mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
chr13_-_21476895	0.429	NM_022459	XPO4	exportin 4
chr9_+_36036900	0.428	NM_021111	RECK	reversion-inducing-cysteine-rich protein with kazal motifs
chr18_+_29671817	0.428	NM_016271	RNF138	ring finger protein 138
chr15_+_69706619	0.428	NM_004856 NM_138555	KIF23	kinesin family member 23
chr4_-_153303663	0.425	NM_001013415	FBXW7	F-box and WD repeat domain containing 7
chr2_+_170683900	0.415	NM_172070	UBR3	ubiquitin protein ligase E3 component n-recognin 3 (putative)
chr15_+_41245635	0.415	NM_001142776 NM_024111	CHAC1	ChaC, cation transport regulator homolog 1 (E. coli)
chr12_-_8025419	0.411	NM_153449	SLC2A14	solute carrier family 2 (facilitated glucose transporter), member 14
chr2_-_72374919	0.409	NM_019885	CYP26B1	cytochrome P450, family 26, subfamily B, polypeptide 1
chr7_+_100026412	0.405	NM_001194990 NM_001194991 NM_001194992	MEPCE	methylphosphate capping enzyme
chr17_+_57232859	0.405	NM_018304	PRR11	proline rich 11
chr2_-_99279935	0.404	NM_001160154	MGAT4A	mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
chr3_+_37903643	0.382	NM_001008392 NM_005808	CTDSPL	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like
chr21_+_17102370	0.376	NM_013396	USP25	ubiquitin specific peptidase 25
chr10_-_94003002	0.376	NM_001178137	CPEB3	cytoplasmic polyadenylation element binding protein 3
chr7_+_100027253	0.375	NM_019606	MEPCE	methylphosphate capping enzyme
chr13_+_20532788	0.371	NM_003453 NM_197968 NM_001190964	ZMYM2	zinc finger, MYM-type 2
chr11_+_111848008	0.371	NM_033425	DIXDC1	DIX domain containing 1
chr5_+_140186658	0.370	NM_018907 NM_031500	PCDHA4	protocadherin alpha 4
chr5_+_140213968	0.370	NM_018910 NM_031852	PCDHA7	protocadherin alpha 7
chr4_-_153273683	0.367	NM_018315	FBXW7	F-box and WD repeat domain containing 7
chr6_-_144385647	0.364	NM_001080951 NM_001080955	PLAGL1	pleiomorphic adenoma gene-like 1
chr11_-_110583120	0.364	NM_020809	ARHGAP20	Rho GTPase activating protein 20
chr8_+_21777165	0.362	NM_015024	XPO7	exportin 7
chr1_-_155532322	0.356	NM_018489	ASH1L	ash1 (absent, small, or homeotic)-like (Drosophila)
chr2_-_171923482	0.355	NM_001136555	TLK1	tousled-like kinase 1
chr9_+_4679557	0.355	NM_017913	CDC37L1	cell division cycle 37 homolog (S. cerevisiae)-like 1
chr5_+_140220811	0.355	NM_018911 NM_031856	PCDHA8	protocadherin alpha 8
chr5_+_140254930	0.354	NM_018903 NM_031864	PCDHA12	protocadherin alpha 12
chr1_-_48462561	0.339	NM_001194986	LOC388630	UPF0632 protein A
chr1_-_22469414	0.339	NM_030761	WNT4	wingless-type MMTV integration site family, member 4
chr1_+_184356128	0.338	NM_030806	C1orf21	chromosome 1 open reading frame 21
chr6_+_15246299	0.338	NM_004973	JARID2	jumonji, AT rich interactive domain 2
chr22_-_42017032	0.330	NM_015704	PPPDE2	PPPDE peptidase domain containing 2
chr1_+_10092990	0.327	NM_001105562 NM_006048	UBE4B	ubiquitination factor E4B
chr13_-_50367027	0.320	NM_002267	KPNA3	karyopherin alpha 3 (importin alpha 4)
chr19_-_17799005	0.309	NM_001080421	UNC13A	unc-13 homolog A (C. elegans)
chr6_-_144329342	0.308	NM_001080952 NM_001080953 NM_001080954 NM_001080956 NM_002656 NM_006718	PLAGL1 HYMAI	pleiomorphic adenoma gene-like 1 hydatidiform mole associated and imprinted (non-protein coding)
chr3_+_187871473	0.306	NM_001167672	LPP	LIM domain containing preferred translocation partner in lipoma
chr2_+_198381021	0.305	NM_001204094	MOB4	MOB family member 4, phocein
chr5_-_16465856	0.305	NM_033414	ZNF622	zinc finger protein 622
chr17_+_40834571	0.304	NM_003632	CNTNAP1	contactin associated protein 1
chr11_+_9406123	0.298	NM_006391	IPO7	importin 7
chr20_+_44650260	0.295	NM_001134771	SLC12A5	solute carrier family 12 (potassium/chloride transporter), member 5
chr18_+_19321544	0.291	NM_020774	MIB1	mindbomb homolog 1 (Drosophila)
chr11_+_125496123	0.291	NM_001274	CHEK1	checkpoint kinase 1
chr20_-_52199635	0.290	NM_006526	ZNF217	zinc finger protein 217
chr5_+_140180782	0.289	NM_018906 NM_031497	PCDHA3	protocadherin alpha 3
chr2_-_220408264	0.288	NM_024536	CHPF	chondroitin polymerizing factor
chr14_+_102228134	0.278	NM_001161725 NM_001161726	PPP2R5C	protein phosphatase 2, regulatory subunit B', gamma
chr15_-_29862926	0.277	NM_015307	FAM189A1	family with sequence similarity 189, member A1
chr18_+_47088400	0.277	NM_006033	LIPG	lipase, endothelial
chr11_-_130184459	0.273	NM_014155	ZBTB44	zinc finger and BTB domain containing 44
chr8_+_67687415	0.270	NM_013257 NM_170709	SGK3	serum/glucocorticoid regulated kinase family, member 3
chr7_-_15726273	0.268	NM_005924	MEOX2	mesenchyme homeobox 2
chr12_-_112037360	0.267	NM_002973	ATXN2	ataxin 2
chr2_-_172017358	0.267	NM_012290	TLK1	tousled-like kinase 1
chr20_+_19193282	0.264	NM_020689	SLC24A3	solute carrier family 24 (sodium/potassium/calcium exchanger), member 3
chr16_-_47007567	0.263	NM_005880	DNAJA2	DnaJ (Hsp40) homolog, subfamily A, member 2
chr2_-_172087823	0.262	NM_001136554	TLK1	tousled-like kinase 1
chr10_-_94050799	0.261	NM_014912	CPEB3	cytoplasmic polyadenylation element binding protein 3
chr9_-_111882209	0.259	NM_032012	C9orf5	chromosome 9 open reading frame 5
chr13_-_36429798	0.259	NM_001195415 NM_001195416 NM_001195430	DCLK1	doublecortin-like kinase 1
chr10_-_79789290	0.257	NM_007055	POLR3A	polymerase (RNA) III (DNA directed) polypeptide A, 155kDa
chr12_-_56881901	0.252	NM_013267	GLS2	glutaminase 2 (liver, mitochondrial)
chr7_+_30323922	0.251	NM_147128	ZNRF2	zinc and ring finger 2
chr20_+_44657812	0.251	NM_020708	SLC12A5	solute carrier family 12 (potassium/chloride transporter), member 5
chr1_+_2160133	0.251	NM_003036	SKI	v-ski sarcoma viral oncogene homolog (avian)
chr3_-_120068077	0.250	NM_001099678	LRRC58	leucine rich repeat containing 58
chr4_+_160188997	0.248	NM_014247	RAPGEF2	Rap guanine nucleotide exchange factor (GEF) 2
chr12_+_66218141	0.244	NM_003483 NM_003484	HMGA2	high mobility group AT-hook 2
chr12_+_83080901	0.243	NM_152588	TMTC2	transmembrane and tetratricopeptide repeat containing 2
chr8_+_67624652	0.243	NM_001033578	SGK3	serum/glucocorticoid regulated kinase family, member 3
chr11_-_65667860	0.241	NM_005438	FOSL1	FOS-like antigen 1
chr1_-_114354906	0.240	NM_018364	RSBN1	round spermatid basic protein 1
chr5_+_140247767	0.239	NM_018902 NM_031861	PCDHA11	protocadherin alpha 11
chr5_+_140201221	0.239	NM_018908 NM_031501	PCDHA5	protocadherin alpha 5
chr2_-_55277698	0.237	NM_020532 NM_153828 NM_207520	RTN4	reticulon 4
chr2_+_198380294	0.234	NM_199482	MOB4	MOB family member 4, phocein
chr16_-_30546145	0.233	NM_023931	ZNF747	zinc finger protein 747
chr9_-_127703294	0.230	NM_002077	GOLGA1	golgin A1
chr1_+_33722158	0.229	NM_152493	ZNF362	zinc finger protein 362
chr10_+_73723992	0.227	NM_004273	CHST3	carbohydrate (chondroitin 6) sulfotransferase 3
chr5_+_140165875	0.226	NM_018900 NM_031410 NM_031411	PCDHA1	protocadherin alpha 1
chr5_+_140207562	0.225	NM_018909 NM_031848 NM_031849	PCDHA6	protocadherin alpha 6
chr17_-_2304217	0.225	NM_020310	MNT	MAX binding protein
chr12_+_122242580	0.221	NM_015048	SETD1B	SET domain containing 1B

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
2.31	2.19e-06	GO:0007399	nervous system development
2.20	2.16e-05	GO:0009653	anatomical structure morphogenesis
6.03	3.76e-05	GO:0007156	homophilic cell adhesion
2.65	3.77e-05	GO:0048699	generation of neurons
1.63	9.57e-05	GO:0032502	developmental process
1.67	9.69e-05	GO:0007275	multicellular organismal development
1.76	9.98e-05	GO:0048731	system development
2.50	1.78e-04	GO:0022008	neurogenesis
3.77	5.40e-04	GO:0016337	cell-cell adhesion
1.66	7.15e-04	GO:0048856	anatomical structure development
1.92	8.40e-04	GO:0006464	protein modification process
2.60	1.68e-03	GO:0030182	neuron differentiation
1.82	4.66e-03	GO:0043412	macromolecule modification
2.82	7.07e-03	GO:0031175	neuron projection development
2.64	9.55e-03	GO:0048666	neuron development
1.18	2.13e-02	GO:0009987	cellular process
2.03	2.29e-02	GO:0010604	positive regulation of macromolecule metabolic process
1.52	3.03e-02	GO:0060255	regulation of macromolecule metabolic process
1.95	3.32e-02	GO:0009893	positive regulation of metabolic process
2.83	4.09e-02	GO:0051247	positive regulation of protein metabolic process
2.72	4.59e-02	GO:0048812	neuron projection morphogenesis

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
15.48	2.64e-03	GO:0000307	cyclin-dependent protein kinase holoenzyme complex

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.17	2.00e-03	GO:0005488	binding
1.29	4.42e-03	GO:0005515	protein binding
2.64	1.50e-02	GO:0004674	protein serine/threonine kinase activity
2.13	2.34e-02	GO:0016301	kinase activity
2.02	2.75e-02	GO:0016772	transferase activity, transferring phosphorus-containing groups
2.27	3.54e-02	GO:0004672	protein kinase activity