Motif ID: AGCUGCC

Z-value: 0.712


Mature miRNA associated with seed AGCUGCC:

NamemiRBase Accession
hsa-miR-22 MIMAT0000077



Activity profile for motif AGCUGCC.

activity profile for motif AGCUGCC


Sorted Z-values histogram for motif AGCUGCC

Sorted Z-values for motif AGCUGCC



Network of associatons between targets according to the STRING database.



First level regulatory network of AGCUGCC

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr8_+_17354562 2.958 NM_001008539
SLC7A2
solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
chr8_+_17396285 2.924 NM_001164771
NM_003046
SLC7A2

solute carrier family 7 (cationic amino acid transporter, y+ system), member 2

chr16_+_57406398 2.512 NM_002996
CX3CL1
chemokine (C-X3-C motif) ligand 1
chr4_-_120549115 2.228 NM_033437
PDE5A
phosphodiesterase 5A, cGMP-specific
chr4_-_120549827 1.526 NM_001083
PDE5A
phosphodiesterase 5A, cGMP-specific
chr7_+_73703704 1.503 NM_003388
NM_032421
CLIP2

CAP-GLY domain containing linker protein 2

chr6_-_32821743 1.346 NM_000593
TAP1
transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
chr4_-_120548329 1.287 NM_033430
PDE5A
phosphodiesterase 5A, cGMP-specific
chr21_-_45660699 1.270 NM_015259
ICOSLG
inducible T-cell co-stimulator ligand
chr8_-_48650703 1.220 NM_005195
CEBPD
CCAAT/enhancer binding protein (C/EBP), delta
chr9_-_134585107 1.215 NM_198679
RAPGEF1
Rap guanine nucleotide exchange factor (GEF) 1
chr11_-_118781612 1.197 NM_182557
BCL9L
B-cell CLL/lymphoma 9-like
chr10_-_105614952 1.171 NM_014631
SH3PXD2A
SH3 and PX domains 2A
chr9_-_134612924 1.137 NM_005312
RAPGEF1
Rap guanine nucleotide exchange factor (GEF) 1
chr8_+_41435666 1.012 NM_178819
AGPAT6
1-acylglycerol-3-phosphate O-acyltransferase 6 (lysophosphatidic acid acyltransferase, zeta)
chr14_+_70078309 0.992 NM_014734
KIAA0247
KIAA0247
chr1_+_166808721 0.969 NM_017542
POGK
pogo transposable element with KRAB domain
chr3_+_111805174 0.963 NM_001171747
NM_024616
C3orf52

chromosome 3 open reading frame 52

chr17_+_40439564 0.951 NM_003152
STAT5A
signal transducer and activator of transcription 5A
chr16_-_75590107 0.931 NM_001077416
NM_001077418
NM_001077419
TMEM231


transmembrane protein 231



Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 27 entries
enrichment   p-value GO term description
4.95 8.70e-03 GO:0021700 developmental maturation
2.41 1.79e-03 GO:0010628 positive regulation of gene expression
2.40 5.86e-03 GO:0045893 positive regulation of transcription, DNA-dependent
2.27 1.18e-04 GO:0006357 regulation of transcription from RNA polymerase II promoter
2.27 3.99e-03 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.23 2.53e-02 GO:0051254 positive regulation of RNA metabolic process
2.20 8.08e-03 GO:0051173 positive regulation of nitrogen compound metabolic process
1.83 3.56e-04 GO:0006464 protein modification process
1.79 6.63e-04 GO:0043412 macromolecule modification
1.65 4.60e-04 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.62 9.87e-04 GO:0051171 regulation of nitrogen compound metabolic process
1.61 3.28e-02 GO:0048523 negative regulation of cellular process
1.58 5.25e-03 GO:0048518 positive regulation of biological process
1.58 2.04e-02 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.57 9.89e-03 GO:0031326 regulation of cellular biosynthetic process
1.56 1.60e-04 GO:0031323 regulation of cellular metabolic process
1.56 3.09e-02 GO:0010556 regulation of macromolecule biosynthetic process
1.56 4.59e-02 GO:0048519 negative regulation of biological process
1.55 4.55e-04 GO:0080090 regulation of primary metabolic process
1.55 1.56e-02 GO:0009889 regulation of biosynthetic process

Gene overrepresentation in compartment category:

Showing 1 to 2 of 2 entries
enrichment   p-value GO term description
2.53 8.80e-03 GO:0045202 synapse
1.20 4.35e-02 GO:0005737 cytoplasm

Gene overrepresentation in function category:

Showing 1 to 4 of 4 entries
enrichment   p-value GO term description
30.59 1.90e-02 GO:0000900 translation repressor activity, nucleic acid binding
2.10 1.92e-02 GO:0043565 sequence-specific DNA binding
1.89 1.70e-02 GO:0003700 sequence-specific DNA binding transcription factor activity
1.27 1.93e-03 GO:0005515 protein binding