Motif ID: AGCUUAU

Z-value: 1.037


Mature miRNA associated with seed AGCUUAU:

NamemiRBase Accession
hsa-miR-21 MIMAT0000076
hsa-miR-590-5p MIMAT0003258



Activity profile for motif AGCUUAU.

activity profile for motif AGCUUAU


Sorted Z-values histogram for motif AGCUUAU

Sorted Z-values for motif AGCUUAU



Network of associatons between targets according to the STRING database.



First level regulatory network of AGCUUAU

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr3_-_18466759 4.526 NM_001195470
NM_002971
SATB1

SATB homeobox 1

chr3_-_18480203 4.522 NM_001131010
SATB1
SATB homeobox 1
chr20_-_23030141 3.635 NM_000361
THBD
thrombomodulin
chr9_-_14398981 3.267 NM_001190738
NFIB
nuclear factor I/B
chr10_+_112631552 3.091 NM_001199492
NM_014456
NM_145341
PDCD4


programmed cell death 4 (neoplastic transformation inhibitor)


chr9_-_14314036 2.994 NM_001190737
NM_005596
NFIB

nuclear factor I/B

chr8_-_9008138 2.750 NM_024607
PPP1R3B
protein phosphatase 1, regulatory subunit 3B
chr5_-_88179278 2.613 NM_001193350
NM_002397
MEF2C

myocyte enhancer factor 2C

chr5_-_88199868 2.471 NM_001131005
NM_001193347
MEF2C

myocyte enhancer factor 2C

chr8_-_9009050 2.432 NM_001201329
PPP1R3B
protein phosphatase 1, regulatory subunit 3B
chr1_+_61542928 2.420 NM_001145511
NFIA
nuclear factor I/A
chr1_+_61547625 2.315 NM_001134673
NM_005595
NFIA

nuclear factor I/A

chr8_-_22549901 2.208 NM_001199880
EGR3
early growth response 3
chr1_+_61547388 2.177 NM_001145512
NFIA
nuclear factor I/A
chr8_-_22550708 2.172 NM_004430
EGR3
early growth response 3
chr8_-_22550057 2.125 NM_001199881
EGR3
early growth response 3
chr5_-_88119604 2.010 NM_001193348
NM_001193349
MEF2C

myocyte enhancer factor 2C

chr1_+_203274646 1.738 NM_006763
BTG2
BTG family, member 2
chr2_+_203241044 1.719 NM_001204
BMPR2
bone morphogenetic protein receptor, type II (serine/threonine kinase)
chr1_+_2160133 1.653 NM_003036
SKI
v-ski sarcoma viral oncogene homolog (avian)

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 24 entries
enrichment   p-value GO term description
60.68 9.01e-03 GO:0070120 ciliary neurotrophic factor-mediated signaling pathway
50.57 1.79e-02 GO:0010224 response to UV-B
37.93 4.94e-02 GO:0051593 response to folic acid
31.12 5.93e-03 GO:0032925 regulation of activin receptor signaling pathway
14.05 2.53e-02 GO:0045768 positive regulation of anti-apoptosis
12.91 6.33e-03 GO:0030510 regulation of BMP signaling pathway
9.10 2.67e-03 GO:0030326 embryonic limb morphogenesis
9.10 2.67e-03 GO:0035113 embryonic appendage morphogenesis
8.02 6.92e-03 GO:0035107 appendage morphogenesis
8.02 6.92e-03 GO:0035108 limb morphogenesis
7.71 9.23e-03 GO:0048736 appendage development
7.71 9.23e-03 GO:0060173 limb development
2.82 1.54e-03 GO:0042981 regulation of apoptosis
2.80 1.80e-03 GO:0043067 regulation of programmed cell death
2.76 2.41e-03 GO:0010941 regulation of cell death
2.27 1.78e-02 GO:0009653 anatomical structure morphogenesis
2.05 9.11e-03 GO:0048523 negative regulation of cellular process
2.01 5.81e-03 GO:0048519 negative regulation of biological process
1.96 2.62e-03 GO:0048518 positive regulation of biological process
1.95 1.34e-02 GO:0048522 positive regulation of cellular process

Nothing significant found in compartment category.

Gene overrepresentation in function category:

Showing 1 to 3 of 3 entries
enrichment   p-value GO term description
75.85 6.05e-04 GO:0004897 ciliary neurotrophic factor receptor activity
2.51 7.18e-03 GO:0001071 nucleic acid binding transcription factor activity
2.51 7.18e-03 GO:0003700 sequence-specific DNA binding transcription factor activity