Motif ID: AGGUAGU

Z-value: 0.571


Mature miRNA associated with seed AGGUAGU:

NamemiRBase Accession
hsa-miR-196a MIMAT0000226
hsa-miR-196b MIMAT0001080



Activity profile for motif AGGUAGU.

activity profile for motif AGGUAGU


Sorted Z-values histogram for motif AGGUAGU

Sorted Z-values for motif AGGUAGU



Network of associatons between targets according to the STRING database.



First level regulatory network of AGGUAGU

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_+_164528586 2.211 NM_001204961
NM_001204963
NM_002585
PBX1


pre-B-cell leukemia homeobox 1


chr7_+_89840999 1.815 NM_001244944
NM_001244945
NM_152999
NM_001040665
NM_001244946
STEAP2




STEAP family member 2, metalloreductase




chr1_-_92371558 1.498 NM_001195684
TGFBR3
transforming growth factor, beta receptor III
chr20_+_37434294 1.402 NM_001172735
NM_015568
PPP1R16B

protein phosphatase 1, regulatory subunit 16B

chr1_-_92351613 1.377 NM_001195683
NM_003243
TGFBR3

transforming growth factor, beta receptor III

chr7_+_94023872 1.177 NM_000089
COL1A2
collagen, type I, alpha 2
chr20_+_30598244 1.160 NM_080625
C20orf160
chromosome 20 open reading frame 160
chr7_-_27183225 1.155 NM_019102
HOXA5
homeobox A5
chr18_+_6834431 1.009 NM_001010000
ARHGAP28
Rho GTPase activating protein 28
chr17_+_68165660 0.994 NM_000891
KCNJ2
potassium inwardly-rectifying channel, subfamily J, member 2
chr15_+_67000929 0.959 NM_001142861
SMAD6
SMAD family member 6
chr12_-_96184510 0.909 NM_021229
NTN4
netrin 4
chr7_-_27205148 0.900 NM_152739
HOXA9
homeobox A9
chr20_+_306205 0.866 NM_006943
SOX12
SRY (sex determining region Y)-box 12
chr15_-_56035176 0.824 NM_173814
PRTG
protogenin
chr2_-_99347588 0.795 NM_012214
MGAT4A
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
chr17_-_46688362 0.784 NM_004502
HOXB7
homeobox B7
chr12_+_12869818 0.781 NM_004064
CDKN1B
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
chr9_+_123850573 0.759 NM_007018
CNTRL
centriolin
chr7_-_27196163 0.756 NM_006896
HOXA7
homeobox A7
chr11_+_44785975 0.726 NM_130783
TSPAN18
tetraspanin 18
chr9_-_14693459 0.711 NM_178566
ZDHHC21
zinc finger, DHHC-type containing 21
chr12_-_59314069 0.704 NM_153377
LRIG3
leucine-rich repeats and immunoglobulin-like domains 3
chr12_-_25055966 0.695 NM_001178093
BCAT1
branched chain amino-acid transaminase 1, cytosolic
chr2_-_39664129 0.687 NM_003618
MAP4K3
mitogen-activated protein kinase kinase kinase kinase 3
chr12_-_25102281 0.659 NM_001178091
NM_001178092
NM_005504
BCAT1


branched chain amino-acid transaminase 1, cytosolic


chr12_-_25055228 0.658 NM_001178094
BCAT1
branched chain amino-acid transaminase 1, cytosolic
chr12_-_59313304 0.653 NM_001136051
LRIG3
leucine-rich repeats and immunoglobulin-like domains 3
chr9_+_128510477 0.651 NM_001134778
PBX3
pre-B-cell leukemia homeobox 3
chr9_-_111882209 0.627 NM_032012
C9orf5
chromosome 9 open reading frame 5
chrX_+_135067573 0.618 NM_001177651
NM_001042537
NM_006359
SLC9A6


solute carrier family 9 (sodium/hydrogen exchanger), member 6


chr16_-_4166185 0.588 NM_001116
ADCY9
adenylate cyclase 9
chr9_+_128509616 0.587 NM_006195
PBX3
pre-B-cell leukemia homeobox 3
chr21_-_40033617 0.587 NM_001243432
NM_001136154
NM_004449
ERG


v-ets erythroblastosis virus E26 oncogene homolog (avian)


chr21_-_39870303 0.585 NM_001136155
NM_182918
ERG

v-ets erythroblastosis virus E26 oncogene homolog (avian)

chr6_-_134373618 0.561 NM_145176
SLC2A12
solute carrier family 2 (facilitated glucose transporter), member 12
chr17_+_28705922 0.557 NM_001304
CPD
carboxypeptidase D
chr10_-_38146221 0.551 NM_021045
ZNF248
zinc finger protein 248
chr1_+_153232178 0.548 NM_000427
LOR
loricrin
chr9_-_79520878 0.531 NM_015225
PRUNE2
prune homolog 2 (Drosophila)
chr8_-_82754427 0.505 NM_022133
NM_152836
NM_152837
SNX16


sorting nexin 16


chr14_-_88459469 0.497 NM_000153
NM_001201401
GALC

galactosylceramidase

chr9_-_72287097 0.483 NM_001163
APBA1
amyloid beta (A4) precursor protein-binding, family A, member 1
chr17_+_28707495 0.481 NM_001199775
CPD
carboxypeptidase D
chr2_+_32390902 0.479 NM_001193513
NM_001193514
NM_001193515
NM_017964
SLC30A6



solute carrier family 30 (zinc transporter), member 6



chr17_+_2699731 0.478 NM_001100398
NM_015085
RAP1GAP2

RAP1 GTPase activating protein 2

chr14_-_88460008 0.475 NM_001201402
GALC
galactosylceramidase
chr11_+_63580922 0.473 NM_138471
C11orf84
chromosome 11 open reading frame 84
chr2_+_109335906 0.462 NM_006267
RANBP2
RAN binding protein 2
chr2_+_189839078 0.427 NM_000090
COL3A1
collagen, type III, alpha 1
chr2_+_242641310 0.413 NM_032329
ING5
inhibitor of growth family, member 5
chr7_+_17338182 0.412 NM_001621
AHR
aryl hydrocarbon receptor
chr3_+_49208979 0.405 NM_173546
KLHDC8B
kelch domain containing 8B
chr15_+_66994669 0.348 NM_005585
SMAD6
SMAD family member 6
chr3_-_36986535 0.341 NM_014831
TRANK1
tetratricopeptide repeat and ankyrin repeat containing 1
chr16_+_69220940 0.339 NM_006750
SNTB2
syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2)
chr17_-_47439326 0.336 NM_001145365
NM_014897
ZNF652

zinc finger protein 652

chr12_+_65004191 0.319 NM_178169
RASSF3
Ras association (RalGDS/AF-6) domain family member 3
chrX_-_24665454 0.294 NM_001163265
NM_004845
PCYT1B

phosphate cytidylyltransferase 1, choline, beta

chr2_-_142889269 0.287 NM_018557
LRP1B
low density lipoprotein receptor-related protein 1B
chr8_-_28243941 0.281 NM_018660
ZNF395
zinc finger protein 395
chr9_-_140196702 0.274 NM_001004354
NRARP
NOTCH-regulated ankyrin repeat protein
chr16_+_22217369 0.270 NM_013302
EEF2K
eukaryotic elongation factor-2 kinase
chr4_+_113066552 0.270 NM_152400
C4orf32
chromosome 4 open reading frame 32
chrX_-_24690740 0.267 NM_001163264
PCYT1B
phosphate cytidylyltransferase 1, choline, beta
chr1_+_113615787 0.262 NM_014813
LRIG2
leucine-rich repeats and immunoglobulin-like domains 2
chr13_-_41240607 0.260 NM_002015
FOXO1
forkhead box O1
chr15_+_52043738 0.259 NM_001142885
NM_014548
TMOD2

tropomodulin 2 (neuronal)

chr6_-_33267128 0.254 NM_001243738
NM_004761
RGL2

ral guanine nucleotide dissociation stimulator-like 2

chr1_-_179112178 0.253 NM_001136000
NM_001168239
NM_005158
ABL2


v-abl Abelson murine leukemia viral oncogene homolog 2


chr8_+_37594078 0.251 NM_001003791
NM_007175
ERLIN2

ER lipid raft associated 2

chr20_+_278200 0.250 NM_033089
ZCCHC3
zinc finger, CCHC domain containing 3
chrX_+_105066531 0.236 NM_198465
NRK
Nik related kinase
chr4_-_18023358 0.235 NM_001166139
NM_153686
LCORL

ligand dependent nuclear receptor corepressor-like

chr3_+_158991035 0.229 NM_001197107
NM_001197108
NM_014575
SCHIP1


schwannomin interacting protein 1


chr6_-_84419108 0.224 NM_001242793
NM_001242794
NM_014841
SNAP91


synaptosomal-associated protein, 91kDa homolog (mouse)


chr12_-_58240746 0.223 NM_005730
CTDSP2
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2
chr8_-_17555158 0.220 NM_020749
MTUS1
microtubule associated tumor suppressor 1
chr7_+_94285676 0.218 NM_001172437
NM_001172438
PEG10

paternally expressed 10

chr6_+_24403144 0.216 NM_020662
MRS2
MRS2 magnesium homeostasis factor homolog (S. cerevisiae)
chr6_-_84418705 0.215 NM_001242792
SNAP91
synaptosomal-associated protein, 91kDa homolog (mouse)
chr19_-_48867149 0.209 NM_018273
TMEM143
transmembrane protein 143
chr4_+_174089889 0.209 NM_017423
GALNT7
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 7 (GalNAc-T7)
chr19_-_51071279 0.208 NM_001080457
LRRC4B
leucine rich repeat containing 4B
chr8_-_17580024 0.207 NM_001166393
MTUS1
microtubule associated tumor suppressor 1
chr9_-_16870719 0.207 NM_017637
BNC2
basonuclin 2
chr21_+_30671217 0.206 NM_001186
BACH1
BTB and CNC homology 1, basic leucine zipper transcription factor 1
chr1_-_115259433 0.205 NM_002524
NRAS
neuroblastoma RAS viral (v-ras) oncogene homolog
chr8_-_17658385 0.203 NM_001001924
NM_001001925
MTUS1

microtubule associated tumor suppressor 1

chr21_+_30671736 0.203 NM_206866
BACH1
BTB and CNC homology 1, basic leucine zipper transcription factor 1
chr9_-_99145991 0.202 NM_007001
SLC35D2
solute carrier family 35, member D2
chr7_-_11871735 0.202 NM_015204
THSD7A
thrombospondin, type I, domain containing 7A
chr3_+_159557649 0.202 NM_001197109
SCHIP1
schwannomin interacting protein 1
chr7_+_94285620 0.200 NM_001040152
NM_001184961
NM_001184962
NM_015068
PEG10



paternally expressed 10



chrX_-_134185978 0.200 NM_001078172
NM_001134321
FAM127B

family with sequence similarity 127, member B

chr8_-_17579729 0.191 NM_001001931
MTUS1
microtubule associated tumor suppressor 1
chr10_+_181410 0.188 NM_001202464
ZMYND11
zinc finger, MYND-type containing 11
chr22_+_50781717 0.186 NM_001242898
NM_001242899
NM_001242900
NM_014678
PPP6R2



protein phosphatase 6, regulatory subunit 2



chr4_-_90758126 0.185 NM_001146054
NM_007308
NM_000345
SNCA


synuclein, alpha (non A4 component of amyloid precursor)


chr4_-_90759446 0.183 NM_001146055
SNCA
synuclein, alpha (non A4 component of amyloid precursor)
chr10_+_97803064 0.182 NM_001134375
NM_001134376
NM_019084
CCNJ


cyclin J


chr3_-_119963141 0.181 NM_001168271
NM_153002
GPR156

G protein-coupled receptor 156

chr9_-_125693778 0.179 NM_020924
ZBTB26
zinc finger and BTB domain containing 26
chr1_-_205601999 0.177 NM_001973
NM_021795
ELK4

ELK4, ETS-domain protein (SRF accessory protein 1)

chr2_+_232260334 0.177 NM_145236
B3GNT7
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7
chr17_-_9862765 0.174 NM_003644
GAS7
growth arrest-specific 7
chr9_+_115513050 0.171 NM_001012994
SNX30
sorting nexin family member 30
chr1_-_179198814 0.170 NM_001136001
NM_001168236
NM_001168237
NM_001168238
NM_007314
ABL2




v-abl Abelson murine leukemia viral oncogene homolog 2




chr2_-_160654736 0.160 NM_001198763
NM_001198764
NM_014880
CD302


CD302 molecule


chr17_-_10101854 0.159 NM_201433
GAS7
growth arrest-specific 7
chr2_-_69870976 0.158 NM_014911
AAK1
AP2 associated kinase 1
chr2_+_113239733 0.154 NM_153712
TTL
tubulin tyrosine ligase
chr2_+_172378856 0.151 NM_001127383
NM_024843
CYBRD1

cytochrome b reductase 1

chr11_+_7273141 0.150 NM_175733
SYT9
synaptotagmin IX
chr10_+_102672325 0.149 NM_001136123
NM_001243770
NM_018121
FAM178A


family with sequence similarity 178, member A


chr8_-_81787015 0.141 NM_001033723
ZNF704
zinc finger protein 704
chr15_+_38544966 0.138 NM_152594
SPRED1
sprouty-related, EVH1 domain containing 1
chr1_+_161087861 0.137 NM_001185092
NM_005600
NM_001185093
NM_001185094
NIT1



nitrilase 1



chr6_+_32146161 0.136 NM_006913
RNF5
ring finger protein 5
chrX_-_77150907 0.134 NM_032121
MAGT1
magnesium transporter 1
chr12_-_106533810 0.133 NM_014840
NUAK1
NUAK family, SNF1-like kinase, 1
chr17_-_46682333 0.125 NM_018952
HOXB6
homeobox B6
chrX_-_140271293 0.124 NM_012317
LDOC1
leucine zipper, down-regulated in cancer 1
chr22_+_30279064 0.119 NM_021090
NM_153050
NM_153051
MTMR3


myotubularin related protein 3


chr14_+_55493837 0.109 NM_080867
NM_199421
SOCS4

suppressor of cytokine signaling 4

chr3_-_28390506 0.108 NM_001134432
NM_001134433
NM_022461
AZI2


5-azacytidine induced 2


chr2_+_26403584 0.108 NM_001191033
FAM59B
family with sequence similarity 59, member B
chr3_-_125094003 0.106 NM_021964
ZNF148
zinc finger protein 148
chr8_+_74206772 0.103 NM_172037
RDH10
retinol dehydrogenase 10 (all-trans)
chr11_-_77899640 0.103 NM_001029859
KCTD21
potassium channel tetramerisation domain containing 21
chr1_+_18957499 0.101 NM_001135254
NM_002584
NM_013945
PAX7


paired box 7


chr4_+_106473776 0.100 NM_001242729
NM_017700
ARHGEF38

Rho guanine nucleotide exchange factor (GEF) 38

chr3_+_14989076 0.093 NM_003298
NR2C2
nuclear receptor subfamily 2, group C, member 2
chr10_+_76871345 0.092 NM_001174156
NM_144660
SAMD8

sterile alpha motif domain containing 8

chr5_-_55290601 0.090 NM_001190981
NM_002184
NM_175767
IL6ST


interleukin 6 signal transducer (gp130, oncostatin M receptor)


chr13_-_33780142 0.089 NM_001243474
NM_052851
STARD13

StAR-related lipid transfer (START) domain containing 13

chr10_+_180404 0.089 NM_006624
NM_001202465
NM_001202466
NM_212479
ZMYND11



zinc finger, MYND-type containing 11



chr2_+_32582046 0.086 NM_016252
BIRC6
baculoviral IAP repeat containing 6
chr1_-_21113160 0.084 NM_016287
HP1BP3
heterochromatin protein 1, binding protein 3
chr5_+_153825497 0.084 NM_001131062
NM_001131063
NM_024632
SAP30L


SAP30-like


chr1_+_91966653 0.084 NM_001134420
CDC7
cell division cycle 7 homolog (S. cerevisiae)
chr4_+_106067754 0.079 NM_001127208
TET2
tet methylcytosine dioxygenase 2
chr1_+_91966365 0.079 NM_001134419
NM_003503
CDC7

cell division cycle 7 homolog (S. cerevisiae)

chr11_+_10772781 0.079 NM_014633
CTR9
Ctr9, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)
chr19_+_47104490 0.077 NM_005184
CALM3
calmodulin 3 (phosphorylase kinase, delta)
chr21_+_17102370 0.077 NM_013396
USP25
ubiquitin specific peptidase 25
chr9_+_91003238 0.077 NM_006717
SPIN1
spindlin 1
chr1_-_51984994 0.077 NM_001981
EPS15
epidermal growth factor receptor pathway substrate 15
chr13_-_33760215 0.075 NM_001243466
NM_178007
STARD13

StAR-related lipid transfer (START) domain containing 13

chrX_+_2746810 0.071 NM_001079855
NM_001184702
NM_001184703
NM_001184704
NM_003918
GYG2




glycogenin 2




chr2_+_26395959 0.069 NM_001168241
FAM59B
family with sequence similarity 59, member B
chr12_-_76478737 0.068 NM_004537
NM_139207
NAP1L1

nucleosome assembly protein 1-like 1

chr4_+_56212381 0.066 NM_024592
SRD5A3
steroid 5 alpha-reductase 3
chr17_-_48278987 0.065 NM_000088
COL1A1
collagen, type I, alpha 1
chrX_-_41782230 0.065 NM_001126054
NM_001126055
NM_003688
CASK


calcium/calmodulin-dependent serine protein kinase (MAGUK family)


chr11_-_796175 0.063 NM_024698
SLC25A22
solute carrier family 25 (mitochondrial carrier: glutamate), member 22
chr2_-_50574891 0.063 NM_138735
NRXN1
neurexin 1
chr8_+_92082423 0.063 NM_016023
OTUD6B
OTU domain containing 6B
chr14_-_68162419 0.061 NM_001252650
NM_016026
RDH11

retinol dehydrogenase 11 (all-trans/9-cis/11-cis)

chr1_-_52521046 0.060 NM_015913
TXNDC12
thioredoxin domain containing 12 (endoplasmic reticulum)
chr22_+_48885255 0.060 NM_001082967
FAM19A5
family with sequence similarity 19 (chemokine (C-C motif)-like), member A5
chr6_-_35464716 0.059 NM_003214
TEAD3
TEA domain family member 3
chr6_-_42419782 0.059 NM_033502
TRERF1
transcriptional regulating factor 1
chr11_+_111944967 0.058 NM_001082969
NM_001082970
NM_018195
C11orf57


chromosome 11 open reading frame 57


chr20_-_31071187 0.057 NM_080616
C20orf112
chromosome 20 open reading frame 112
chr8_+_28351694 0.057 NM_017412
NM_145866
FZD3

frizzled family receptor 3

chr22_+_48972117 0.054 NM_015381
FAM19A5
family with sequence similarity 19 (chemokine (C-C motif)-like), member A5
chr12_-_57400199 0.053 NM_014830
ZBTB39
zinc finger and BTB domain containing 39
chrX_+_17653412 0.052 NM_001136024
NHS
Nance-Horan syndrome (congenital cataracts and dental anomalies)
chrX_+_48555124 0.051 NM_003173
SUV39H1
suppressor of variegation 3-9 homolog 1 (Drosophila)
chr3_-_149688638 0.050 NM_002628
NM_053024
PFN2

profilin 2

chr2_+_170590241 0.049 NM_144711
KLHL23
kelch-like 23 (Drosophila)
chr2_-_145090038 0.047 NM_001164629
GTDC1
glycosyltransferase-like domain containing 1
chr6_-_99797530 0.047 NM_032511
C6orf168
chromosome 6 open reading frame 168
chr9_-_77567735 0.047 NM_017998
C9orf40
chromosome 9 open reading frame 40
chrX_-_134156488 0.042 NM_001078173
FAM127C
family with sequence similarity 127, member C
chr13_-_33859835 0.042 NM_178006
STARD13
StAR-related lipid transfer (START) domain containing 13
chr3_+_101498028 0.041 NM_145037
FAM55C
family with sequence similarity 55, member C
chr14_-_95608054 0.039 NM_030621
DICER1
dicer 1, ribonuclease type III
chr15_-_34502269 0.039 NM_024713
C15orf29
chromosome 15 open reading frame 29
chr3_+_158787040 0.038 NM_001197113
NM_001197114
NM_001042705
NM_001042706
NM_001197100
IQCJ-SCHIP1

IQCJ


IQCJ-SCHIP1 readthrough

IQ motif containing J


chr1_-_17765052 0.037 NM_001136204
RCC2
regulator of chromosome condensation 2
chr1_-_200589856 0.037 NM_014875
KIF14
kinesin family member 14
chr12_-_123451031 0.036 NM_001243013
NM_001243014
NM_019624
NM_019625
NM_203444
ABCB9




ATP-binding cassette, sub-family B (MDR/TAP), member 9




chr7_-_102789334 0.036 NM_001122838
NM_198990
NAPEPLD

N-acyl phosphatidylethanolamine phospholipase D

chr6_+_32605182 0.035 NM_002122
HLA-DQA1
major histocompatibility complex, class II, DQ alpha 1
chr5_-_39074494 0.033 NM_152756
RICTOR
RPTOR independent companion of MTOR, complex 2
chr17_+_53342320 0.032 NM_002126
HLF
hepatic leukemia factor
chr14_-_77787023 0.031 NM_013382
POMT2
protein-O-mannosyltransferase 2
chr9_-_99801365 0.028 NM_001333
CTSL2
cathepsin L2
chrX_+_67718623 0.027 NM_001195214
NM_173834
YIPF6

Yip1 domain family, member 6

chr1_-_53793743 0.027 NM_001018054
NM_004631
NM_017522
NM_033300
LRP8



low density lipoprotein receptor-related protein 8, apolipoprotein e receptor



chr17_-_9940004 0.023 NM_201432
GAS7
growth arrest-specific 7
chr10_+_11059854 0.022 NM_006561
CELF2
CUGBP, Elav-like family member 2
chr9_+_6413139 0.021 NM_152896
UHRF2
ubiquitin-like with PHD and ring finger domains 2
chr21_+_47878764 0.021 NM_001146114
NM_001146115
NM_001146116
NM_015151
NM_206889
NM_206890
NM_206891
DIP2A






DIP2 disco-interacting protein 2 homolog A (Drosophila)






chr12_+_123868608 0.021 NM_020382
SETD8
SET domain containing (lysine methyltransferase) 8
chr14_-_92572950 0.018 NM_001127696
NM_001127697
NM_001164774
NM_001164776
NM_001164777
NM_001164778
NM_001164779
NM_001164780
NM_001164781
NM_001164782
NM_004993
NM_030660
ATXN3











ataxin 3











chr9_-_99801924 0.017 NM_001201575
CTSL2
cathepsin L2
chr1_+_36023389 0.017 NM_001014839
NM_001014841
NM_014284
NCDN


neurochondrin



Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
11.46 6.76e-05 GO:0048706 embryonic skeletal system development

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
36.56 3.82e-04 GO:0005583 fibrillar collagen
100.52 1.27e-02 GO:0005584 collagen type I

Nothing significant found in function category.