Motif ID: AHR_ARNT_ARNT2.p2

Z-value: 1.012


Transcription factors associated with AHR_ARNT_ARNT2.p2:

Gene SymbolEntrez IDGene Name
AHR 196 aryl hydrocarbon receptor
ARNT 405 aryl hydrocarbon receptor nuclear translocator
ARNT2 9915 aryl-hydrocarbon receptor nuclear translocator 2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.p-valuePlot
ARNTchr1_-_1508490620.395.3e-02Click!
AHRchr7_+_17338182-0.096.7e-01Click!
ARNT2chr15_+_80696569-0.086.9e-01Click!


Activity profile for motif AHR_ARNT_ARNT2.p2.

activity profile for motif AHR_ARNT_ARNT2.p2


Sorted Z-values histogram for motif AHR_ARNT_ARNT2.p2

Sorted Z-values for motif AHR_ARNT_ARNT2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of AHR_ARNT_ARNT2.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr5_+_151151483 1.362 G3BP1
GTPase activating protein (SH3 domain) binding protein 1
chr19_+_17666381 0.990 GLT25D1
glycosyltransferase 25 domain containing 1
chr4_+_94750041 0.956 NM_005172
 ATOH1
atonal homolog 1 (Drosophila)
chr5_+_151151516 0.955 G3BP1
GTPase activating protein (SH3 domain) binding protein 1
chr12_-_88974094 0.920 NM_000899
NM_003994
 KITLG

KIT ligand

chr1_-_205290756 0.895 NM_030952
 NUAK2
NUAK family, SNF1-like kinase, 2
chr5_+_151151511 0.865 G3BP1
GTPase activating protein (SH3 domain) binding protein 1
chr15_+_84115979 0.815 NM_003027
 SH3GL3
SH3-domain GRB2-like 3
chr5_+_151151514 0.800 G3BP1
GTPase activating protein (SH3 domain) binding protein 1
chr6_+_43738757 0.798 VEGFA
vascular endothelial growth factor A
chr5_+_151151462 0.751 NM_005754
NM_198395
 G3BP1

GTPase activating protein (SH3 domain) binding protein 1

chr20_-_10654429 0.734 NM_000214
 JAG1
jagged 1
chr20_-_10654139 0.710 JAG1
jagged 1
chr8_-_80679897 0.709 NM_001040708
NM_012258
 HEY1

hairy/enhancer-of-split related with YRPW motif 1

chr1_+_221053000 0.678 HLX
H2.0-like homeobox
chr2_+_219433517 0.626 NM_005444
 RQCD1
RCD1 required for cell differentiation1 homolog (S. pombe)
chr9_-_34590137 0.603 NM_001207011
 CNTFR
ciliary neurotrophic factor receptor
chr15_-_79382839 0.575 RASGRF1
Ras protein-specific guanine nucleotide-releasing factor 1
chr16_+_30709913 0.552


chr10_-_105452878 0.548 SH3PXD2A
SH3 and PX domains 2A

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 184 entries
enrichment   p-value GO term description
3.38 7.79e-03 GO:0060349 bone morphogenesis
2.88 2.51e-03 GO:0031124 mRNA 3'-end processing
2.67 1.87e-02 GO:0051147 regulation of muscle cell differentiation
2.63 3.49e-07 GO:0006184 GTP catabolic process
2.52 2.52e-02 GO:0031123 RNA 3'-end processing
2.47 4.06e-06 GO:0046039 GTP metabolic process
2.23 7.42e-03 GO:0010769 regulation of cell morphogenesis involved in differentiation
2.21 9.16e-03 GO:0022604 regulation of cell morphogenesis
2.13 4.36e-05 GO:0009203 ribonucleoside triphosphate catabolic process
2.13 4.36e-05 GO:0009207 purine ribonucleoside triphosphate catabolic process
2.12 5.28e-05 GO:0009146 purine nucleoside triphosphate catabolic process
2.11 1.03e-03 GO:0051169 nuclear transport
2.09 9.29e-05 GO:0009143 nucleoside triphosphate catabolic process
2.09 9.29e-05 GO:0009154 purine ribonucleotide catabolic process
2.09 1.84e-03 GO:0006913 nucleocytoplasmic transport
2.07 1.34e-04 GO:0009261 ribonucleotide catabolic process
2.06 1.07e-02 GO:0010552 positive regulation of gene-specific transcription from RNA polymerase II promoter
2.00 3.04e-04 GO:0006195 purine nucleotide catabolic process
1.98 3.45e-04 GO:0072523 purine-containing compound catabolic process
1.97 2.92e-02 GO:0030900 forebrain development

Gene overrepresentation in compartment category:

Showing 1 to 20 of 28 entries
enrichment   p-value GO term description
1.50 7.08e-03 GO:0005694 chromosome
1.49 1.35e-08 GO:0005654 nucleoplasm
1.45 2.59e-10 GO:0031981 nuclear lumen
1.42 1.16e-11 GO:0070013 intracellular organelle lumen
1.41 1.11e-11 GO:0031974 membrane-enclosed lumen
1.41 3.85e-11 GO:0043233 organelle lumen
1.40 4.80e-10 GO:0044428 nuclear part
1.40 2.38e-02 GO:0044451 nucleoplasm part
1.38 2.39e-08 GO:0005829 cytosol
1.27 1.44e-05 GO:0043228 non-membrane-bounded organelle
1.27 1.44e-05 GO:0043232 intracellular non-membrane-bounded organelle
1.27 1.64e-02 GO:0012505 endomembrane system
1.25 5.07e-14 GO:0005634 nucleus
1.24 1.17e-12 GO:0044446 intracellular organelle part
1.23 9.30e-12 GO:0044422 organelle part
1.23 1.76e-02 GO:0031090 organelle membrane
1.21 4.06e-11 GO:0044444 cytoplasmic part
1.20 2.80e-19 GO:0043231 intracellular membrane-bounded organelle
1.20 4.73e-19 GO:0043227 membrane-bounded organelle
1.20 5.04e-17 GO:0005737 cytoplasm

Gene overrepresentation in function category:

Showing 1 to 20 of 34 entries
enrichment   p-value GO term description
2.24 5.38e-07 GO:0003924 GTPase activity
1.98 4.80e-08 GO:0005525 GTP binding
1.95 2.01e-03 GO:0010843 promoter binding
1.94 1.32e-03 GO:0000975 regulatory region DNA binding
1.94 1.32e-03 GO:0001067 regulatory region nucleic acid binding
1.94 1.32e-03 GO:0044212 transcription regulatory region DNA binding
1.92 2.83e-07 GO:0019001 guanyl nucleotide binding
1.92 2.83e-07 GO:0032561 guanyl ribonucleotide binding
1.77 1.75e-03 GO:0008134 transcription factor binding
1.72 3.28e-03 GO:0016563 transcription activator activity
1.66 5.59e-07 GO:0043565 sequence-specific DNA binding
1.55 3.61e-05 GO:0019899 enzyme binding
1.55 1.96e-02 GO:0004674 protein serine/threonine kinase activity
1.51 2.19e-06 GO:0030528 transcription regulator activity
1.49 1.22e-05 GO:0001071 nucleic acid binding transcription factor activity
1.49 1.22e-05 GO:0003700 sequence-specific DNA binding transcription factor activity
1.49 1.45e-04 GO:0003723 RNA binding
1.49 1.01e-03 GO:0016773 phosphotransferase activity, alcohol group as acceptor
1.48 5.88e-12 GO:0035639 purine ribonucleoside triphosphate binding
1.47 2.69e-15 GO:0000166 nucleotide binding