Motif ID: ALX1.p2

Z-value: 0.813


Transcription factors associated with ALX1.p2:

Gene SymbolEntrez IDGene Name
ALX1 8092 ALX homeobox 1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.p-valuePlot
ALX1chr12_+_856738840.414.4e-02Click!


Activity profile for motif ALX1.p2.

activity profile for motif ALX1.p2


Sorted Z-values histogram for motif ALX1.p2

Sorted Z-values for motif ALX1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ALX1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr9_-_74675498 2.553 NM_001128618
C9orf57
chromosome 9 open reading frame 57
chr1_+_78470593 1.947 NM_007034
DNAJB4
DnaJ (Hsp40) homolog, subfamily B, member 4
chr11_+_7618416 1.807 PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr19_-_48752921 1.536 NM_001184901
NM_001184903
NM_014959
CARD8


caspase recruitment domain family, member 8


chr7_+_74188308 1.402 NM_000265
NCF1
NCF1B
neutrophil cytosolic factor 1
neutrophil cytosolic factor 1B pseudogene
chr13_-_52980628 1.293 NM_018676
NM_199263
THSD1

thrombospondin, type I, domain containing 1

chr2_-_233877901 1.286 NGEF
neuronal guanine nucleotide exchange factor
chr7_+_22766765 1.174 NM_000600
IL6
interleukin 6 (interferon, beta 2)
chrM_-_9203 1.169


chr2_+_132480063 1.145 NM_013310
C2orf27A
chromosome 2 open reading frame 27A
chr12_-_10021932 1.098 CLEC2B
C-type lectin domain family 2, member B
chr5_+_61874561 1.073 NM_181506
LRRC70
leucine rich repeat containing 70
chrX_+_66788682 0.992 NM_001011645
AR
androgen receptor
chr19_-_14169970 0.951 NM_001145028
PALM3
paralemmin 3
chr12_-_10022457 0.926 NM_005127
CLEC2B
C-type lectin domain family 2, member B
chr17_-_48945338 0.843 NM_001243877
TOB1
transducer of ERBB2, 1
chr2_-_233877920 0.735 NM_019850
NGEF
neuronal guanine nucleotide exchange factor
chr7_+_27282163 0.720 NM_001989
EVX1
even-skipped homeobox 1
chr1_-_76397975 0.700 NM_080868
ASB17
ankyrin repeat and SOCS box containing 17
chr8_-_110661007 0.697 NM_001099747
NM_001099748
NM_001099749
NM_001099750
NM_017786
SYBU




syntabulin (syntaxin-interacting)




chr6_-_133084585 0.697 NM_078488
VNN2
vanin 2
chr3_+_121286777 0.641 NM_001012659
ARGFX
arginine-fifty homeobox
chr22_-_23922376 0.628 NM_020070
NM_152855
IGLL1

immunoglobulin lambda-like polypeptide 1

chr2_-_163008913 0.624 NM_002054
GCG
glucagon
chr19_+_39899749 0.622


chr1_+_74701070 0.612 NM_015978
TNNI3K
TNNI3 interacting kinase
chr16_-_72206348 0.604 NM_001160213
PMFBP1
polyamine modulated factor 1 binding protein 1
chrX_-_62570968 0.575 NM_001012968
SPIN4
spindlin family, member 4
chr11_-_51412447 0.570 NM_001005272
OR4A5
olfactory receptor, family 4, subfamily A, member 5
chr7_+_150688143 0.562 NM_000603
NOS3
nitric oxide synthase 3 (endothelial cell)
chr19_+_56347943 0.559 NM_134444
NLRP4
NLR family, pyrin domain containing 4
chr12_+_131438451 0.559 NM_198827
GPR133
G protein-coupled receptor 133
chr19_-_23941571 0.554 NM_138286
ZNF681
zinc finger protein 681
chr3_+_107096187 0.543 NM_032600
CCDC54
coiled-coil domain containing 54
chr2_-_99279935 0.540 NM_001160154
MGAT4A
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
chr4_-_159956332 0.539 NM_152543
C4orf45
chromosome 4 open reading frame 45
chr1_+_168250277 0.537 NM_005149
TBX19
T-box 19
chr10_-_113933517 0.530 GPAM
glycerol-3-phosphate acyltransferase, mitochondrial
chr6_-_76203256 0.525 NM_015687
FILIP1
filamin A interacting protein 1
chr19_-_48759141 0.498 NM_001184902
NM_001184904
CARD8

caspase recruitment domain family, member 8

chr4_-_186578122 0.498 NM_001145674
NM_001145675
SORBS2

sorbin and SH3 domain containing 2

chr4_-_186577858 0.497 SORBS2
sorbin and SH3 domain containing 2
chr6_+_28317687 0.492 NM_001242894
NM_001242895
NM_024493
ZKSCAN3


zinc finger with KRAB and SCAN domains 3


chr17_-_46651809 0.489 NM_002146
HOXB3
homeobox B3
chr3_-_168864325 0.488 NM_001105078
MECOM
MDS1 and EVI1 complex locus
chr17_-_3030844 0.485 NM_003555
OR1G1
olfactory receptor, family 1, subfamily G, member 1
chr15_+_94899163 0.485 NM_001159644
MCTP2
multiple C2 domains, transmembrane 2
chr9_-_21350885 0.464 NM_021002
IFNA6
interferon, alpha 6
chr12_+_80603232 0.454 NM_173591
OTOGL
otogelin-like
chr5_-_149466126 0.452 CSF1R
colony stimulating factor 1 receptor
chr11_-_124190092 0.445 NM_001002918
OR8D2
olfactory receptor, family 8, subfamily D, member 2
chr2_-_48115846 0.436 NM_025133
FBXO11
F-box protein 11
chr19_+_2819942 0.436 ZNF554
zinc finger protein 554
chr19_-_58864820 0.435 NM_130786
A1BG
alpha-1-B glycoprotein
chr1_+_84647342 0.430 NM_001242862
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr6_-_31648140 0.428 NM_025262
LY6G5C
lymphocyte antigen 6 complex, locus G5C
chr14_+_57046490 0.419 NM_017799
C14orf101
chromosome 14 open reading frame 101
chr5_-_149466094 0.418 CSF1R
colony stimulating factor 1 receptor
chr5_-_22853730 0.417 NM_004061
CDH12
cadherin 12, type 2 (N-cadherin 2)
chrX_-_131261871 0.413 NM_194277
FRMD7
FERM domain containing 7
chr2_+_103089761 0.411 NM_001011552
SLC9A4
solute carrier family 9 (sodium/hydrogen exchanger), member 4
chr5_+_147795459 0.403 FBXO38
F-box protein 38
chr4_-_72649734 0.402 NM_000583
GC
group-specific component (vitamin D binding protein)
chr8_+_98703361 0.401 MTDH
metadherin
chr19_-_51872256 0.401 NM_152353
CLDND2
claudin domain containing 2
chr14_-_106926393 0.400 IGHA1
IGHG1
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
chrM_+_5245 0.391


chrX_-_21776158 0.388 NM_014332
SMPX
small muscle protein, X-linked
chr2_+_88047603 0.386 NM_002665
NM_001032392
PLGLB2
PLGLB1
plasminogen-like B2
plasminogen-like B1
chr9_+_5231401 0.380 NM_002195
INSL4
insulin-like 4 (placenta)
chr7_-_25268057 0.375 NM_022150
NPVF
neuropeptide VF precursor
chr21_-_31859666 0.375 NM_181608
KRTAP19-2
keratin associated protein 19-2
chr4_-_21699317 0.364 NM_001035003
KCNIP4
Kv channel interacting protein 4
chr7_-_122635753 0.364 NM_016945
TAS2R16
taste receptor, type 2, member 16
chr2_+_190540710 0.363 NM_144708
ANKAR
ankyrin and armadillo repeat containing
chr2_-_87248942 0.362 NM_002665
NM_001032392
PLGLB2
PLGLB1
plasminogen-like B2
plasminogen-like B1
chr3_-_160101443 0.357 NM_001190242
IFT80
intraflagellar transport 80 homolog (Chlamydomonas)
chr6_+_47624222 0.357 NM_153839
GPR111
G protein-coupled receptor 111
chr5_+_36606667 0.352 SLC1A3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr19_+_21324826 0.346 NM_133473
ZNF431
zinc finger protein 431
chr1_+_54359859 0.342 NM_000792
NM_001039715
NM_001039716
NM_213593
DIO1



deiodinase, iodothyronine, type I



chr17_+_18647325 0.341 NM_031456
FBXW10
F-box and WD repeat domain containing 10
chr4_+_156587861 0.339 NM_000856
NM_001130682
NM_001130686
NM_001130687
NM_001130683
NM_001130685
GUCY1A3





guanylate cyclase 1, soluble, alpha 3





chr1_+_241695433 0.335 NM_003679
KMO
kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
chr15_+_38227456 0.331 NM_152453
TMCO5A
transmembrane and coiled-coil domains 5A
chr5_+_121465214 0.331 NM_207317
ZNF474
zinc finger protein 474
chr11_-_1629614 0.329 NM_001012708
KRTAP5-3
keratin associated protein 5-3
chr12_+_101988746 0.326 NM_002465
NM_206819
NM_206820
NM_206821
MYBPC1



myosin binding protein C, slow type



chrX_-_10535476 0.326 NM_001193278
NM_001193279
NM_001193280
NM_001193281
MID1



midline 1 (Opitz/BBB syndrome)



chr6_-_25874439 0.321 NM_001098486
NM_006632
SLC17A3

solute carrier family 17 (sodium phosphate), member 3

chrM_+_8857 0.320


chr15_+_69307033 0.320 NM_001184779
NM_024505
NOX5

NADPH oxidase, EF-hand calcium binding domain 5

chr19_+_48758931 0.311 LOC100505812
uncharacterized LOC100505812
chr13_+_41885340 0.309 NM_001110798
NM_018527
NM_024561
NAA16


N(alpha)-acetyltransferase 16, NatA auxiliary subunit


chr14_-_106471439 0.308 IGHA1
IGHG1
IGHM
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant mu
chrX_-_31526414 0.300 NM_004014
DMD
dystrophin
chr22_+_21821458 0.299 NM_001207052
TMEM191C
transmembrane protein 191C
chr8_-_86290333 0.299 NM_001128829
NM_001128830
NM_001128831
NM_001738
CA1



carbonic anhydrase I



chr3_-_9920633 0.298 NM_022094
CIDEC
cell death-inducing DFFA-like effector c
chr6_-_39072412 0.295 C6orf64
chromosome 6 open reading frame 64
chr5_-_149466173 0.293 CSF1R
colony stimulating factor 1 receptor
chr5_-_41213513 0.290 NM_000065
C6
complement component 6
chrM_+_9182 0.289


chr5_-_22853435 0.288 CDH12
cadherin 12, type 2 (N-cadherin 2)
chr14_+_94385239 0.285 NM_001207071
NM_138344
FAM181A

family with sequence similarity 181, member A

chr10_-_23633771 0.284 NM_153714
C10orf67
chromosome 10 open reading frame 67
chr3_+_158991035 0.282 NM_001197107
NM_001197108
NM_014575
SCHIP1


schwannomin interacting protein 1


chr10_+_135160843 0.281 NM_001145201
NM_145202
PRAP1

proline-rich acidic protein 1

chr1_+_84630575 0.281 NM_001242860
NM_001242861
PRKACB

protein kinase, cAMP-dependent, catalytic, beta

chr9_-_21202201 0.279 NM_021057
IFNA7
interferon, alpha 7
chr17_-_29641068 0.279 EVI2B
ecotropic viral integration site 2B
chr1_-_42776760 0.279


chr1_-_89641722 0.277 NM_207398
GBP7
guanylate binding protein 7
chr2_+_207804277 0.275 NM_173077
CPO
carboxypeptidase O
chr2_+_98962617 0.274 NM_001079878
NM_001298
CNGA3

cyclic nucleotide gated channel alpha 3

chr18_-_51880942 0.274 NM_139171
STARD6
StAR-related lipid transfer (START) domain containing 6
chr11_+_28131830 0.273 METTL15
methyltransferase like 15
chrX_+_101854095 0.272 NM_001199818
NM_001168479
NM_001168480
NM_001168485
ARMCX5-GPRASP2
ARMCX5


ARMCX5-GPRASP2 readthrough
armadillo repeat containing, X-linked 5


chr5_+_81601165 0.269 NM_001017971
ATP6AP1L
ATPase, H+ transporting, lysosomal accessory protein 1-like
chr19_+_21264952 0.268 NM_182515
ZNF714
zinc finger protein 714
chr11_+_73661363 0.266 NM_153614
DNAJB13
DnaJ (Hsp40) homolog, subfamily B, member 13
chr14_+_21236585 0.256 NM_022360
EDDM3B
epididymal protein 3B
chr1_+_244515936 0.253 NM_001012970
C1orf100
chromosome 1 open reading frame 100
chr18_+_47088400 0.252 NM_006033
LIPG
lipase, endothelial
chr11_+_5646206 0.252 NM_021616
TRIM34
tripartite motif containing 34
chr1_+_84767288 0.251 NM_001134663
SAMD13
sterile alpha motif domain containing 13
chr17_-_71228257 0.249 FAM104A
family with sequence similarity 104, member A
chr12_-_16759531 0.248 NM_018640
LMO3
LIM domain only 3 (rhombotin-like 2)
chr20_+_32250089 0.242 NM_080825
C20orf144
chromosome 20 open reading frame 144
chr16_+_53479685 0.241 RBL2
retinoblastoma-like 2 (p130)
chr10_+_49609641 0.241 NM_002750
NM_139046
NM_139047
NM_139049
MAPK8



mitogen-activated protein kinase 8



chr9_-_21368005 0.240 NM_006900
IFNA1
IFNA13
interferon, alpha 1
interferon, alpha 13
chr14_+_21457964 0.239 NM_001029991
NM_022734
METTL17

methyltransferase like 17

chr3_+_127641901 0.238 NM_207335
KBTBD12
kelch repeat and BTB (POZ) domain containing 12
chr4_+_166131170 0.237 NM_001161521
NM_001161522
KLHL2

kelch-like 2, Mayven (Drosophila)

chr13_-_48987652 0.235 NM_001162498
LPAR6
lysophosphatidic acid receptor 6
chr3_+_57094468 0.234 NM_181727
SPATA12
spermatogenesis associated 12
chr12_-_16759430 0.234 LMO3
LIM domain only 3 (rhombotin-like 2)
chr1_+_115572414 0.231 NM_000549
TSHB
thyroid stimulating hormone, beta
chr7_-_44580857 0.230 NM_001101648
NM_013389
NPC1L1

NPC1 (Niemann-Pick disease, type C1, gene)-like 1

chr12_-_7656285 0.229 NM_004244
NM_203416
CD163

CD163 molecule

chr9_+_102677457 0.228 STX17
syntaxin 17
chr6_-_30899926 0.228 NM_205854
SFTA2
surfactant associated 2
chr9_-_21305311 0.224 NM_002169
IFNA5
interferon, alpha 5
chr6_-_41254392 0.223 NM_001242589
NM_001242590
NM_018643
TREM1


triggering receptor expressed on myeloid cells 1


chr19_+_9486991 0.222 NM_001172651
ZNF177
zinc finger protein 177
chr13_+_50025687 0.221 NM_001160308
SETDB2
SET domain, bifurcated 2
chr7_-_7758237 0.220 NM_002947
RPA3
replication protein A3, 14kDa
chr19_-_21646685 0.220


chr7_+_37723378 0.218


chr10_+_74870209 0.218 NM_015901
NUDT13
nudix (nucleoside diphosphate linked moiety X)-type motif 13
chr2_+_234959345 0.216 NM_006944
SPP2
secreted phosphoprotein 2, 24kDa
chr16_-_11375094 0.212 NM_002761
PRM1
protamine 1
chr6_-_110501164 0.212 NM_001024934
NM_001024935
NM_001024936
NM_003931
WASF1



WAS protein family, member 1



chr1_+_39922262 0.211 MACF1
microtubule-actin crosslinking factor 1
chr12_-_75905412 0.211 NM_007043
KRR1
KRR1, small subunit (SSU) processome component, homolog (yeast)
chr19_-_21950322 0.209 NM_173531
ZNF100
zinc finger protein 100
chr19_+_36486042 0.208 NM_001042631
SDHAF1
succinate dehydrogenase complex assembly factor 1
chr3_-_69037498 0.207 C3orf64
chromosome 3 open reading frame 64
chrM_+_9725 0.207


chr5_+_161275897 0.205 NM_001127646
GABRA1
gamma-aminobutyric acid (GABA) A receptor, alpha 1
chr6_-_28411228 0.205 NM_001012455
ZSCAN23
zinc finger and SCAN domain containing 23
chrX_-_33357725 0.201 NM_000109
DMD
dystrophin
chr20_+_34556528 0.200 NM_001207076
NM_080834
C20orf152

chromosome 20 open reading frame 152

chr17_+_64960754 0.199 NM_014405
CACNG4
calcium channel, voltage-dependent, gamma subunit 4
chr7_+_129984629 0.198 NM_001127441
NM_001127442
NM_080385
CPA5


carboxypeptidase A5


chr6_-_79675672 0.197 PHIP
pleckstrin homology domain interacting protein
chr18_+_29769986 0.197 NM_005925
MEP1B
meprin A, beta
chr1_-_197552304 0.197 DENND1B
DENN/MADD domain containing 1B
chr21_-_27945267 0.196 NM_052954
CYYR1
cysteine/tyrosine-rich 1
chr15_-_65398578 0.196 NM_001163692
UBAP1L
ubiquitin associated protein 1-like
chr19_+_15838833 0.196 NM_013939
OR10H2
olfactory receptor, family 10, subfamily H, member 2
chr3_+_148583042 0.195 NM_001870
CPA3
carboxypeptidase A3 (mast cell)
chr19_+_2328628 0.194 NM_001077238
NM_152988
SPPL2B

signal peptide peptidase-like 2B

chr9_-_21217303 0.193 NM_002173
IFNA16
interferon, alpha 16
chr3_-_178969402 0.193 NM_014407
KCNMB3
potassium large conductance calcium-activated channel, subfamily M beta member 3
chr19_+_39786964 0.192 NM_172140
IL29
interleukin 29 (interferon, lambda 1)
chr1_-_76076762 0.190 NM_001130058
NM_152697
SLC44A5

solute carrier family 44, member 5

chr14_+_101295409 0.190 MEG3
maternally expressed 3 (non-protein coding)
chr7_+_129906702 0.190 NM_001869
CPA2
carboxypeptidase A2 (pancreatic)
chr19_-_9092017 0.190 NM_024690
MUC16
mucin 16, cell surface associated
chr1_-_163113938 0.189 RGS5
regulator of G-protein signaling 5
chr17_+_61086897 0.187 NM_025185
TANC2
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
chr15_+_41099254 0.186 NM_001077268
ZFYVE19
zinc finger, FYVE domain containing 19
chr19_-_22605075 0.183 NM_001098626
ZNF98
zinc finger protein 98
chr11_-_114466471 0.182 NM_001077639
NM_017678
FAM55D

family with sequence similarity 55, member D

chr7_-_16844606 0.182 NM_006408
AGR2
anterior gradient 2 homolog (Xenopus laevis)
chrX_+_105412297 0.180 NM_001171020
NM_152423
MUM1L1

melanoma associated antigen (mutated) 1-like 1

chr10_-_27529263 0.180 NM_145698
ACBD5
acyl-CoA binding domain containing 5
chr19_-_20150251 0.179 NM_033196
ZNF682
zinc finger protein 682
chr15_-_69707358 0.178 LOC145694
uncharacterized LOC145694
chr5_-_75008245 0.176 NM_152408
POC5
POC5 centriolar protein homolog (Chlamydomonas)
chr7_-_112758604 0.175 LOC401397
uncharacterized LOC401397
chrX_-_101112548 0.174 NM_032946
NXF5
nuclear RNA export factor 5
chr1_+_207262211 0.173 NM_001017365
NM_001017366
C4BPB

complement component 4 binding protein, beta

chr11_+_5653484 0.172 NM_130390
TRIM34
tripartite motif containing 34
chr5_+_140220811 0.169 NM_018911
NM_031856
PCDHA8

protocadherin alpha 8

chr5_+_68667280 0.168 NM_133339
RAD17
RAD17 homolog (S. pombe)
chr9_+_79968344 0.166 VPS13A
vacuolar protein sorting 13 homolog A (S. cerevisiae)
chr6_-_2751153 0.165 NM_001012418
MYLK4
myosin light chain kinase family, member 4

Gene Ontology Analysis

Nothing significant found in process category.

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.56 8.04e-04 GO:0005576 extracellular region

Nothing significant found in function category.