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• Mean activities

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• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)
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Motif ID: AR.p2

Z-value: 0.462

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr1_-_1149495	2.903	NM_003327	TNFRSF4	tumor necrosis factor receptor superfamily, member 4
chr1_-_150738232	1.813		CTSS	cathepsin S
chr1_-_150738255	1.709		CTSS	cathepsin S
chr16_-_67970734	1.128	NM_002801	PSMB10	proteasome (prosome, macropain) subunit, beta type, 10
chr1_-_150738292	1.013	NM_001199739 NM_004079	CTSS	cathepsin S
chr1_-_173174611	0.515		TNFSF4	tumor necrosis factor (ligand) superfamily, member 4
chr5_-_16738346	0.515		MYO10	myosin X
chr3_-_58563070	0.482		FAM107A	family with sequence similarity 107, member A
chr6_-_154831788	0.440		CNKSR3	CNKSR family member 3
chr5_-_13944588	0.393	NM_001369	DNAH5	dynein, axonemal, heavy chain 5
chr16_-_67970651	0.347		PSMB10	proteasome (prosome, macropain) subunit, beta type, 10
chr14_-_65346554	0.338		SPTB	spectrin, beta, erythrocytic
chr6_-_35696359	0.330	NM_001145775	FKBP5	FK506 binding protein 5
chr1_-_20250051	0.329	NM_014589	PLA2G2E	phospholipase A2, group IIE
chr3_-_71180061	0.310	NM_001244815	FOXP1	forkhead box P1
chr11_-_113577023	0.299	NM_030770	TMPRSS5	transmembrane protease, serine 5
chr14_-_106692107	0.290		IGHV4-31 IGHA1 IGHD IGHG1 IGHG3	immunoglobulin heavy variable 4-31 immunoglobulin heavy constant alpha 1 immunoglobulin heavy constant delta immunoglobulin heavy constant gamma 1 (G1m marker) immunoglobulin heavy constant gamma 3 (G3m marker)
chr19_-_7058644	0.253	NM_001164425	MBD3L3	methyl-CpG binding domain protein 3-like 3
chr13_+_97794050	0.238		MBNL2	muscleblind-like 2 (Drosophila)
chr18_+_55816546	0.229	NM_001144965 NM_001144968 NM_001144969 NM_001144971	NEDD4L	neural precursor cell expressed, developmentally down-regulated 4-like
chr10_-_62332666	0.214	NM_001204404	ANK3	ankyrin 3, node of Ranvier (ankyrin G)
chr16_-_67977956	0.202	NM_000229	LCAT	lecithin-cholesterol acyltransferase
chr11_+_63974144	0.190	NM_031471 NM_178443	FERMT3	fermitin family member 3
chr15_+_52311408	0.190	NM_002748	MAPK6	mitogen-activated protein kinase 6
chr5_-_58571916	0.181	NM_001197220	PDE4D	phosphodiesterase 4D, cAMP-specific
chr14_-_107218786	0.181		IGHA1 IGHG1 IGHM	immunoglobulin heavy constant alpha 1 immunoglobulin heavy constant gamma 1 (G1m marker) immunoglobulin heavy constant mu
chr19_+_35630391	0.170	NM_005031	FXYD1	FXYD domain containing ion transport regulator 1
chr1_-_156786500	0.163	NM_001161441 NM_001161442 NM_001161444 NM_003975	SH2D2A	SH2 domain containing 2A
chr3_-_58563490	0.153	NM_001076778 NM_007177	FAM107A	family with sequence similarity 107, member A
chr15_+_52311432	0.152		MAPK6	mitogen-activated protein kinase 6
chrX_+_8432870	0.146	NM_001001888	VCX3B VCX3A	variable charge, X-linked 3B variable charge, X-linked 3A
chr10_+_75673346	0.143		PLAU	plasminogen activator, urokinase
chr8_-_23177481	0.139		LOXL2	lysyl oxidase-like 2
chr4_+_186064416	0.129	NM_001151	SLC25A4	solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4
chr1_+_151129104	0.128	NM_001204848 NM_024575	TNFAIP8L2-SCNM1 TNFAIP8L2	TNFAIP8L2-SCNM1 readthrough tumor necrosis factor, alpha-induced protein 8-like 2
chr8_+_100025534	0.121		VPS13B	vacuolar protein sorting 13 homolog B (yeast)
chr19_-_15391261	0.120	NM_014299 NM_058243	BRD4	bromodomain containing 4
chr1_-_202129705	0.117		PTPN7	protein tyrosine phosphatase, non-receptor type 7
chr19_+_3708358	0.115		TJP3	tight junction protein 3 (zona occludens 3)
chr11_+_74862031	0.112	NM_001145212 NM_007256	SLCO2B1	solute carrier organic anion transporter family, member 2B1
chr11_+_63974190	0.111		FERMT3	fermitin family member 3
chr4_+_71494460	0.109	NM_031889	ENAM	enamelin
chr19_+_7030593	0.104	NM_001136507	MBD3L5	methyl-CpG binding domain protein 3-like 5
chr18_+_72166568	0.102		CNDP2	CNDP dipeptidase 2 (metallopeptidase M20 family)
chr7_+_150147882	0.099		GIMAP8	GTPase, IMAP family member 8
chr12_+_113416267	0.099	NM_001032731 NM_002535 NM_016817	OAS2	2'-5'-oligoadenylate synthetase 2, 69/71kDa
chr11_-_7847518	0.097	NM_153445	OR5P3	olfactory receptor, family 5, subfamily P, member 3
chr14_-_107113943	0.093		IGHA1 IGHG1	immunoglobulin heavy constant alpha 1 immunoglobulin heavy constant gamma 1 (G1m marker)
chrX_+_150345055	0.091	NM_004224	GPR50	G protein-coupled receptor 50
chr11_+_113659924	0.089		LOC390251	SH3-domain GRB2-like 1 pseudogene
chr4_+_1953831	0.082		WHSC1	Wolf-Hirschhorn syndrome candidate 1
chr1_-_202129731	0.078		PTPN7	protein tyrosine phosphatase, non-receptor type 7
chr8_+_62200524	0.078	NM_173519	CLVS1	clavesin 1
chr1_-_149982528	0.072	NM_020205	OTUD7B	OTU domain containing 7B
chr4_-_155312448	0.068	NM_017639	DCHS2	dachsous 2 (Drosophila)
chr6_+_31638727	0.067	NM_021221	LY6G5B	lymphocyte antigen 6 complex, locus G5B
chr2_+_231280906	0.066		SP100	SP100 nuclear antigen
chr3_-_120401401	0.065	NM_000187	HGD	homogentisate 1,2-dioxygenase
chr4_-_69817478	0.065	NM_024743	UGT2A3	UDP glucuronosyltransferase 2 family, polypeptide A3
chr15_+_59908908	0.064		GCNT3	glucosaminyl (N-acetyl) transferase 3, mucin type
chr1_-_156785938	0.064	NM_001161443	SH2D2A	SH2 domain containing 2A
chr5_-_149324282	0.062	NM_000440	PDE6A	phosphodiesterase 6A, cGMP-specific, rod, alpha
chr1_-_159684274	0.061	NM_000567	CRP	C-reactive protein, pentraxin-related
chr15_+_59908724	0.061		GCNT3	glucosaminyl (N-acetyl) transferase 3, mucin type
chr14_-_107048697	0.061		IGHG1	immunoglobulin heavy constant gamma 1 (G1m marker)
chr20_-_1309809	0.060	NM_080489	SDCBP2	syndecan binding protein (syntenin) 2
chr10_+_70847817	0.060	NM_002727	SRGN	serglycin
chr11_+_117070039	0.060	NM_001001522 NM_003186	TAGLN	transgelin
chr20_+_138121	0.060	NM_139074	DEFB127	defensin, beta 127
chr14_-_106610338	0.058		IGHV4-31 IGHG1	immunoglobulin heavy variable 4-31 immunoglobulin heavy constant gamma 1 (G1m marker)
chr3_+_46448678	0.057	NM_003965 NM_001130910	CCRL2	chemokine (C-C motif) receptor-like 2
chr15_-_40398286	0.056	NM_001003942 NM_001003943	BMF	Bcl2 modifying factor
chr9_-_114247024	0.056	NM_001080398	KIAA0368	KIAA0368
chr20_-_3149070	0.051	NM_014731	ProSAPiP1	ProSAPiP1 protein
chr14_-_106994001	0.050		IGHV3-48 IGH@ IGHA1 IGHM	immunoglobulin heavy variable 3-48 immunoglobulin heavy locus immunoglobulin heavy constant alpha 1 immunoglobulin heavy constant mu
chr14_-_107099379	0.050		IGHG1 IGHG3	immunoglobulin heavy constant gamma 1 (G1m marker) immunoglobulin heavy constant gamma 3 (G3m marker)
chr5_+_67588395	0.046	NM_001242466	PIK3R1	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr12_+_10163225	0.044	NM_001129998 NM_205852	CLEC12B	C-type lectin domain family 12, member B
chr7_+_20655244	0.044	NM_001163941	ABCB5	ATP-binding cassette, sub-family B (MDR/TAP), member 5
chr12_-_91505541	0.043	NM_002345	LUM	lumican
chr19_-_54876671	0.042	NM_002287 NM_021706	LAIR1	leukocyte-associated immunoglobulin-like receptor 1
chrX_-_6453158	0.041	NM_016379	VCX2 VCX3A	variable charge, X-linked 2 variable charge, X-linked 3A
chr3_+_184032849	0.039	NM_182917	EIF4G1	eukaryotic translation initiation factor 4 gamma, 1
chr17_-_48264039	0.035		COL1A1	collagen, type I, alpha 1
chr11_-_64528186	0.035	NM_001164716 NM_005609	PYGM	phosphorylase, glycogen, muscle
chr19_+_50472856	0.035		SIGLEC16	sialic acid binding Ig-like lectin 16 (gene/pseudogene)
chr11_+_45115563	0.034	NM_020229	PRDM11	PR domain containing 11
chr10_-_13544944	0.033	NM_001100912 NM_152751	BEND7	BEN domain containing 7
chr14_-_106725232	0.032		ZCWPW2 IGHV3-23 IGKV3-20 IGK@	zinc finger, CW type with PWWP domain 2 immunoglobulin heavy variable 3-23 immunoglobulin kappa variable 3-20 immunoglobulin kappa locus
chr1_+_153388999	0.032	NM_176823	S100A7A	S100 calcium binding protein A7A
chrY_-_26194115	0.032	NM_001003894 NM_001003895 NM_004680 NM_170723	CDY1B CDY1	chromodomain protein, Y-linked, 1B chromodomain protein, Y-linked, 1
chr12_+_21525801	0.030	NM_000415	IAPP	islet amyloid polypeptide
chrY_+_27768241	0.030	NM_001003894 NM_001003895 NM_004680 NM_170723	CDY1B CDY1	chromodomain protein, Y-linked, 1B chromodomain protein, Y-linked, 1
chr16_-_20338808	0.030	NM_001007240 NM_001007241 NM_001007242 NM_001502	GP2	glycoprotein 2 (zymogen granule membrane)
chr3_-_190167597	0.028	NM_207316	TMEM207	transmembrane protein 207
chr2_+_88472657	0.026	NM_018271	THNSL2	threonine synthase-like 2 (S. cerevisiae)
chr6_+_29079586	0.025	NM_001005216	OR2J3	olfactory receptor, family 2, subfamily J, member 3
chr4_-_10686314	0.025	NM_052964	CLNK	cytokine-dependent hematopoietic cell linker
chr14_-_107199126	0.024		IGHG3	immunoglobulin heavy constant gamma 3 (G3m marker)
chr17_+_37824506	0.023	NM_002686	PNMT	phenylethanolamine N-methyltransferase
chr20_-_42816217	0.023	NM_020433 NM_175913	JPH2	junctophilin 2
chr7_+_65420507	0.023		VKORC1L1	vitamin K epoxide reductase complex, subunit 1-like 1
chr9_-_77502635	0.022	NM_001177310	TRPM6	transient receptor potential cation channel, subfamily M, member 6
chrX_+_152082985	0.021	NM_001178106 NM_001178107 NM_001178108 NM_001178109 NM_001178110 NM_007150	ZNF185	zinc finger protein 185 (LIM domain)
chrY_+_20137666	0.021	NM_001001722 NM_004825	CDY2B CDY2A	chromodomain protein, Y-linked, 2B chromodomain protein, Y-linked, 2A
chr3_-_50608421	0.021	NM_001171741	C3orf18	chromosome 3 open reading frame 18
chr19_-_41934634	0.020	NM_198540	B3GNT8	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 8
chr20_-_23731558	0.020	NM_001898	CST1	cystatin SN
chr14_-_21493858	0.019		NDRG2	NDRG family member 2
chr3_-_120400957	0.018		HGD	homogentisate 1,2-dioxygenase
chr2_+_241544819	0.018	NM_001195381 NM_001195382	GPR35	G protein-coupled receptor 35
chr12_-_7245048	0.016		C1R	complement component 1, r subcomponent
chr1_-_104239071	0.016	NM_001008221	AMY1A	amylase, alpha 1A (salivary)
chr1_+_104198140	0.016	NM_001008221	AMY1A	amylase, alpha 1A (salivary)
chr14_-_21493910	0.014	NM_016250 NM_201535 NM_201536 NM_201537	NDRG2	NDRG family member 2
chr5_+_94982480	0.013	NM_001131066 NM_001131065 NM_173362	RFESD	Rieske (Fe-S) domain containing
chr1_+_104292278	0.013	NM_001008221	AMY1A	amylase, alpha 1A (salivary)
chrY_-_19992072	0.013	NM_001001722 NM_004825	CDY2B CDY2A	chromodomain protein, Y-linked, 2B chromodomain protein, Y-linked, 2A
chr11_+_61102035	0.007		DAK	dihydroxyacetone kinase 2 homolog (S. cerevisiae)
chr2_-_109605668	0.007	NM_022336	EDAR	ectodysplasin A receptor
chr15_+_85291802	0.007	NM_014630	ZNF592	zinc finger protein 592
chr19_+_4791727	0.007	NM_018708	FEM1A	fem-1 homolog a (C. elegans)
chr19_+_48497907	0.006	NM_022142	ELSPBP1	epididymal sperm binding protein 1
chr1_+_200863948	0.005	NM_001142569	C1orf106	chromosome 1 open reading frame 106
chr9_+_27524311	0.003	NM_020124	IFNK	interferon, kappa
chr5_+_140625146	0.002	NM_018935	PCDHB15	protocadherin beta 15
chr14_-_106573348	0.002		IGHV4-31 IGHA1 IGHA2 IGHG1 IGHG3 IGHM	immunoglobulin heavy variable 4-31 immunoglobulin heavy constant alpha 1 immunoglobulin heavy constant alpha 2 (A2m marker) immunoglobulin heavy constant gamma 1 (G1m marker) immunoglobulin heavy constant gamma 3 (G3m marker) immunoglobulin heavy constant mu
chr6_+_31730772	0.001	NM_001039651	C6orf26	chromosome 6 open reading frame 26

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
3.95	4.70e-04	GO:0006955	immune response
2.98	2.00e-03	GO:0002376	immune system process
43.05	1.88e-02	GO:0050710	negative regulation of cytokine secretion

Nothing significant found in compartment category.

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
23.68	2.04e-05	GO:0003823	antigen binding