Motif ID: ARNT_ARNT2_BHLHB2_MAX_MYC_USF1.p2

Z-value: 1.936


Transcription factors associated with ARNT_ARNT2_BHLHB2_MAX_MYC_USF1.p2:

Gene SymbolEntrez IDGene Name
ARNT 405 aryl hydrocarbon receptor nuclear translocator
ARNT2 9915 aryl-hydrocarbon receptor nuclear translocator 2
BHLHB2 8553 basic helix-loop-helix domain containing, class B, 2
MAX 4149 MYC associated factor X
MYC 4609 v-myc myelocytomatosis viral oncogene homolog (avian)
USF1 7391 upstream transcription factor 1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.p-valuePlot
MAXchr14_-_655692210.841.7e-07Click!
USF1chr1_-_161015752,
chr1_-_161015688		0.536.1e-03Click!
ARNT2chr15_+_806965690.491.3e-02Click!
ARNTchr1_-_150849211-0.481.5e-02Click!
MYCchr8_+_1287484760.135.2e-01Click!
BHLHE40chr3_+_50211410.115.9e-01Click!


Activity profile for motif ARNT_ARNT2_BHLHB2_MAX_MYC_USF1.p2.

activity profile for motif ARNT_ARNT2_BHLHB2_MAX_MYC_USF1.p2


Sorted Z-values histogram for motif ARNT_ARNT2_BHLHB2_MAX_MYC_USF1.p2

Sorted Z-values for motif ARNT_ARNT2_BHLHB2_MAX_MYC_USF1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ARNT_ARNT2_BHLHB2_MAX_MYC_USF1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr8_+_17354562 16.075 NM_001008539
 SLC7A2
solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
chr15_+_89182038 11.500 NM_002201
 ISG20
interferon stimulated exonuclease gene 20kDa
chr19_+_45504686 11.496 NM_006509
 RELB
v-rel reticuloendotheliosis viral oncogene homolog B
chr1_-_154193044 9.400 C1orf43
chromosome 1 open reading frame 43
chr9_+_115913227 8.304 NM_001860
 SLC31A2
solute carrier family 31 (copper transporters), member 2
chr9_+_115913266 8.009 SLC31A2
solute carrier family 31 (copper transporters), member 2
chr19_+_18284578 7.939 NM_006332
 IFI30
interferon, gamma-inducible protein 30
chr7_-_47622127 7.857 TNS3
tensin 3
chr19_+_49458151 7.118 BAX
BCL2-associated X protein
chr1_-_212873306 7.081 NM_018664
 BATF3
basic leucine zipper transcription factor, ATF-like 3
chr19_+_49458129 6.853 BAX
BCL2-associated X protein
chr16_+_31044849 6.693 STX4
syntaxin 4
chr19_+_49458031 6.550 NM_004324
NM_138761
NM_138763
NM_138764
 BAX



BCL2-associated X protein



chr19_+_10765106 6.500 ILF3
interleukin enhancer binding factor 3, 90kDa
chr8_+_104383701 6.459 CTHRC1
collagen triple helix repeat containing 1
chr13_+_113951537 6.443 LAMP1
lysosomal-associated membrane protein 1
chr16_+_31044881 6.322 NM_004604
 STX4
syntaxin 4
chr19_+_18284619 6.281 IFI30
interferon, gamma-inducible protein 30
chr19_+_18284631 6.220 IFI30
interferon, gamma-inducible protein 30
chr15_+_67358194 6.002 NM_005902
 SMAD3
SMAD family member 3

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 39 entries
enrichment   p-value GO term description
2.50 3.11e-02 GO:0042254 ribosome biogenesis
2.32 1.58e-03 GO:0006605 protein targeting
2.32 8.25e-03 GO:0006913 nucleocytoplasmic transport
2.30 1.08e-02 GO:0051169 nuclear transport
2.23 8.81e-03 GO:0000375 RNA splicing, via transesterification reactions
2.17 2.80e-02 GO:0022613 ribonucleoprotein complex biogenesis
2.15 1.92e-05 GO:0044419 interspecies interaction between organisms
2.05 8.48e-03 GO:0034660 ncRNA metabolic process
1.96 8.44e-04 GO:0006886 intracellular protein transport
1.88 5.07e-06 GO:0006396 RNA processing
1.86 3.46e-04 GO:0034613 cellular protein localization
1.85 4.50e-04 GO:0070727 cellular macromolecule localization
1.70 1.66e-04 GO:0046907 intracellular transport
1.67 4.64e-02 GO:0016071 mRNA metabolic process
1.62 6.70e-10 GO:0016070 RNA metabolic process
1.61 1.17e-03 GO:0045184 establishment of protein localization
1.61 1.54e-03 GO:0015031 protein transport
1.59 1.18e-09 GO:0010467 gene expression
1.57 4.58e-04 GO:0008104 protein localization
1.54 1.23e-13 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process

Gene overrepresentation in compartment category:

Showing 1 to 20 of 28 entries
enrichment   p-value GO term description
2.26 2.17e-11 GO:0005730 nucleolus
2.07 4.62e-03 GO:0016604 nuclear body
1.69 4.04e-03 GO:0030529 ribonucleoprotein complex
1.69 1.04e-02 GO:0005740 mitochondrial envelope
1.66 3.35e-02 GO:0031966 mitochondrial membrane
1.64 5.31e-13 GO:0031981 nuclear lumen
1.60 1.93e-03 GO:0031967 organelle envelope
1.58 2.44e-14 GO:0031974 membrane-enclosed lumen
1.57 3.37e-13 GO:0043233 organelle lumen
1.57 4.80e-13 GO:0070013 intracellular organelle lumen
1.57 1.32e-12 GO:0044428 nuclear part
1.57 8.68e-07 GO:0005654 nucleoplasm
1.57 4.01e-03 GO:0031975 envelope
1.56 6.16e-03 GO:0044451 nucleoplasm part
1.53 2.34e-02 GO:0044429 mitochondrial part
1.35 4.66e-04 GO:0005829 cytosol
1.32 2.32e-03 GO:0031090 organelle membrane
1.31 4.41e-13 GO:0044446 intracellular organelle part
1.31 6.79e-13 GO:0044422 organelle part
1.28 1.15e-10 GO:0005634 nucleus

Gene overrepresentation in function category:

Showing 1 to 6 of 6 entries
enrichment   p-value GO term description
9.68 1.84e-02 GO:0001085 RNA polymerase II transcription factor binding
1.79 1.39e-07 GO:0003723 RNA binding
1.28 2.44e-02 GO:0000166 nucleotide binding
1.26 6.83e-04 GO:0003676 nucleic acid binding
1.24 2.02e-11 GO:0005515 protein binding
1.10 1.54e-05 GO:0005488 binding