Motif ID: ATF6.p2

Z-value: 1.479


Transcription factors associated with ATF6.p2:

Gene SymbolEntrez IDGene Name
ATF6 22926 activating transcription factor 6

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.p-valuePlot
ATF6chr1_+_1617361090.164.3e-01Click!


Activity profile for motif ATF6.p2.

activity profile for motif ATF6.p2


Sorted Z-values histogram for motif ATF6.p2

Sorted Z-values for motif ATF6.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ATF6.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr8_-_22550708 5.729 NM_004430
 EGR3
early growth response 3
chr12_-_124068864 4.410


chr7_+_94024201 3.255 COL1A2
collagen, type I, alpha 2
chr5_-_172198160 3.249 NM_004417
 DUSP1
dual specificity phosphatase 1
chr2_+_28615771 3.113 NM_005253
 FOSL2
FOS-like antigen 2
chr10_-_64576074 2.853 EGR2
early growth response 2
chr10_-_64576123 2.827 NM_000399
NM_001136177
NM_001136179
 EGR2


early growth response 2


chr9_-_84304378 2.782 TLE1
transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
chr2_+_28615668 2.773 FOSL2
FOS-like antigen 2
chr16_-_88772732 2.671 NM_001171815
 RNF166
ring finger protein 166
chr1_+_84767288 2.644 NM_001134663
 SAMD13
sterile alpha motif domain containing 13
chr16_-_88772807 2.635 NM_178841
 RNF166
ring finger protein 166
chr12_+_27397077 2.589 NM_015000
 STK38L
serine/threonine kinase 38 like
chr8_-_9009050 2.565 NM_001201329
 PPP1R3B
protein phosphatase 1, regulatory subunit 3B
chr3_+_8543508 2.549 NM_014583
 LMCD1
LIM and cysteine-rich domains 1
chr9_+_79074067 2.469 NM_001097633
NM_001490
 GCNT1

glucosaminyl (N-acetyl) transferase 1, core 2

chr2_+_28615695 2.447 FOSL2
FOS-like antigen 2
chr5_+_137801166 2.431 EGR1
early growth response 1
chr7_+_94023872 2.413 NM_000089
 COL1A2
collagen, type I, alpha 2
chr11_+_7535000 2.276 NM_003621
 PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2)

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 24 entries
enrichment   p-value GO term description
10.31 1.14e-02 GO:0048194 Golgi vesicle budding
10.31 1.14e-02 GO:0048200 Golgi transport vesicle coating
10.31 1.14e-02 GO:0048205 COPI coating of Golgi vesicle
7.73 2.83e-04 GO:0048199 vesicle targeting, to, from or within Golgi
5.80 2.32e-02 GO:0006901 vesicle coating
5.57 3.42e-02 GO:0006900 membrane budding
5.16 2.52e-02 GO:0006903 vesicle targeting
2.81 8.39e-03 GO:0048193 Golgi vesicle transport
2.14 7.21e-04 GO:0006886 intracellular protein transport
2.13 1.39e-05 GO:0070727 cellular macromolecule localization
2.11 2.61e-05 GO:0034613 cellular protein localization
1.84 1.89e-05 GO:0015031 protein transport
1.81 4.55e-05 GO:0045184 establishment of protein localization
1.78 3.85e-06 GO:0008104 protein localization
1.72 4.02e-03 GO:0046907 intracellular transport
1.63 6.27e-05 GO:0033036 macromolecule localization
1.63 1.51e-04 GO:0051641 cellular localization
1.55 1.95e-02 GO:0051649 establishment of localization in cell
1.28 5.98e-04 GO:0044260 cellular macromolecule metabolic process
1.24 2.46e-03 GO:0043170 macromolecule metabolic process

Gene overrepresentation in compartment category:

Showing 1 to 20 of 23 entries
enrichment   p-value GO term description
7.73 4.03e-03 GO:0030663 COPI coated vesicle membrane
6.37 1.92e-02 GO:0030137 COPI-coated vesicle
2.11 7.28e-06 GO:0000139 Golgi membrane
1.95 2.15e-05 GO:0044431 Golgi apparatus part
1.61 1.46e-02 GO:0044432 endoplasmic reticulum part
1.59 1.51e-06 GO:0012505 endomembrane system
1.58 8.31e-04 GO:0005783 endoplasmic reticulum
1.57 3.12e-03 GO:0005794 Golgi apparatus
1.44 2.04e-02 GO:0005654 nucleoplasm
1.42 1.83e-04 GO:0031090 organelle membrane
1.37 2.74e-03 GO:0044428 nuclear part
1.37 1.58e-02 GO:0031981 nuclear lumen
1.27 1.01e-06 GO:0044446 intracellular organelle part
1.25 2.88e-06 GO:0044444 cytoplasmic part
1.25 4.98e-06 GO:0044422 organelle part
1.23 1.68e-11 GO:0043231 intracellular membrane-bounded organelle
1.23 2.22e-11 GO:0043227 membrane-bounded organelle
1.21 5.96e-04 GO:0005634 nucleus
1.19 1.83e-06 GO:0005737 cytoplasm
1.18 1.08e-08 GO:0043229 intracellular organelle

Gene overrepresentation in function category:

Showing 1 to 5 of 5 entries
enrichment   p-value GO term description
15.47 9.43e-03 GO:0046923 ER retention sequence binding
1.55 9.18e-03 GO:0001071 nucleic acid binding transcription factor activity
1.55 9.18e-03 GO:0003700 sequence-specific DNA binding transcription factor activity
1.14 3.13e-02 GO:0005515 protein binding
1.09 2.79e-03 GO:0005488 binding