Motif ID: BPTF.p2

Z-value: 1.346


Transcription factors associated with BPTF.p2:

Gene SymbolEntrez IDGene Name
BPTF 2186 bromodomain PHD finger transcription factor

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.p-valuePlot
BPTFchr17_+_658216250.654.5e-04Click!


Activity profile for motif BPTF.p2.

activity profile for motif BPTF.p2


Sorted Z-values histogram for motif BPTF.p2

Sorted Z-values for motif BPTF.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of BPTF.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_-_186877869 6.860 NM_021069
SORBS2
sorbin and SH3 domain containing 2
chr7_-_150329285 5.644 GIMAP6
GTPase, IMAP family member 6
chr1_+_84768333 4.963 NM_001134664
SAMD13
sterile alpha motif domain containing 13
chr9_+_6215785 4.745 NM_001199640
NM_001199641
NM_033439
IL33


interleukin 33


chr3_-_64211111 3.499 NM_198859
PRICKLE2
prickle homolog 2 (Drosophila)
chr9_-_14086901 3.497 NFIB
nuclear factor I/B
chr4_+_41700736 3.346 LIMCH1
LIM and calponin homology domains 1
chr18_-_22930826 3.024


chr6_-_30712294 2.760 NM_003897
IER3
immediate early response 3
chr1_+_63249771 2.755 NM_032852
NM_178221
ATG4C

ATG4 autophagy related 4 homolog C (S. cerevisiae)

chr8_-_27941387 2.744 NM_001010906
C8orf80
chromosome 8 open reading frame 80
chr4_+_41614725 2.693 LIMCH1
LIM and calponin homology domains 1
chr4_+_41614933 2.646 LIMCH1
LIM and calponin homology domains 1
chr1_-_1623942 2.569 SLC35E2B
SLC35E2
solute carrier family 35, member E2B
solute carrier family 35, member E2
chrX_-_62570968 2.506 NM_001012968
SPIN4
spindlin family, member 4
chr10_-_131762017 2.466 NM_001005463
EBF3
early B-cell factor 3
chr17_-_62097937 2.444 NM_001099786
NM_001099787
NM_001099788
NM_001099789
ICAM2



intercellular adhesion molecule 2



chr6_+_130758261 2.347 NM_052913
TMEM200A
transmembrane protein 200A
chr4_+_41614911 2.329 NM_001112719
NM_001112720
LIMCH1

LIM and calponin homology domains 1

chr11_-_33891361 2.290 NM_001142316
LMO2
LIM domain only 2 (rhombotin-like 1)
chr1_-_45452215 2.280 EIF2B3
eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa
chr19_-_49540072 2.254 NM_033377
CGB1
CGB2
chorionic gonadotropin, beta polypeptide 1
chorionic gonadotropin, beta polypeptide 2
chr5_+_139027907 2.211 CXXC5
CXXC finger protein 5
chr12_-_8043743 2.192 SLC2A14
solute carrier family 2 (facilitated glucose transporter), member 14
chr1_-_45452266 2.180 NM_001166588
NM_020365
EIF2B3

eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa

chr4_-_186697065 2.176 NM_001145673
SORBS2
sorbin and SH3 domain containing 2
chr12_-_42877413 2.172 NM_001144881
PRICKLE1
prickle homolog 1 (Drosophila)
chr1_-_17308072 2.105 NM_001135247
NM_017459
MFAP2

microfibrillar-associated protein 2

chr4_+_156587861 2.087 NM_000856
NM_001130682
NM_001130686
NM_001130687
NM_001130683
NM_001130685
GUCY1A3





guanylate cyclase 1, soluble, alpha 3





chr4_-_186577858 2.071 SORBS2
sorbin and SH3 domain containing 2
chr18_-_53089722 2.056 NM_001243233
TCF4
transcription factor 4
chr8_+_29952921 1.916 NM_001128208
NM_015344
LEPROTL1

leptin receptor overlapping transcript-like 1

chr10_+_35484054 1.892 NM_182717
NM_182718
NM_182719
NM_182720
CREM



cAMP responsive element modulator



chr2_-_75788027 1.875 FAM176A
family with sequence similarity 176, member A
chr16_-_90076528 1.830 NM_024043
DBNDD1
dysbindin (dystrobrevin binding protein 1) domain containing 1
chr17_-_66951381 1.814 NM_007168
ABCA8
ATP-binding cassette, sub-family A (ABC1), member 8
chr12_+_56915587 1.770 NM_002898
RBMS2
RNA binding motif, single stranded interacting protein 2
chr2_-_75788079 1.750 NM_001135032
FAM176A
family with sequence similarity 176, member A
chr9_-_14313509 1.693 NFIB
nuclear factor I/B
chr16_+_29827489 1.693 NM_024516
C16orf53
chromosome 16 open reading frame 53
chr1_+_84767288 1.690 NM_001134663
SAMD13
sterile alpha motif domain containing 13
chr9_+_79115548 1.673 NM_001097636
GCNT1
glucosaminyl (N-acetyl) transferase 1, core 2
chr7_+_150434435 1.635 NM_018384
GIMAP5
GTPase, IMAP family member 5
chr19_-_48752921 1.632 NM_001184901
NM_001184903
NM_014959
CARD8


caspase recruitment domain family, member 8


chr20_-_17539480 1.592 NM_001161705
BFSP1
beaded filament structural protein 1, filensin
chr21_-_31869427 1.591 NM_181610
KRTAP19-4
keratin associated protein 19-4
chr11_-_33891258 1.581 LMO2
LIM domain only 2 (rhombotin-like 1)
chr11_-_33890931 1.557 LMO2
LIM domain only 2 (rhombotin-like 1)
chr12_-_42983412 1.551 NM_153026
PRICKLE1
prickle homolog 1 (Drosophila)
chrX_-_117119282 1.548 NM_001168299
KLHL13
kelch-like 13 (Drosophila)
chr5_-_140013034 1.535 NM_000591
CD14
CD14 molecule
chr7_+_150434679 1.530 GIMAP5
GTPase, IMAP family member 5
chr5_+_139027868 1.525 CXXC5
CXXC finger protein 5
chr5_+_68800003 1.497 NM_001205255
OCLN
occludin
chr9_+_75136716 1.495 NM_138691
TMC1
transmembrane channel-like 1
chr21_-_27945267 1.480 NM_052954
CYYR1
cysteine/tyrosine-rich 1
chr3_-_17741511 1.469 NM_001134381
TBC1D5
TBC1 domain family, member 5
chr2_+_33359607 1.459 NM_000627
NM_001166264
NM_001166265
NM_001166266
LTBP1



latent transforming growth factor beta binding protein 1



chr16_+_53479685 1.450 RBL2
retinoblastoma-like 2 (p130)
chr4_-_90759446 1.434 NM_001146055
SNCA
synuclein, alpha (non A4 component of amyloid precursor)
chr2_-_44586854 1.430 NM_001042385
NM_001042386
PREPL

prolyl endopeptidase-like

chr10_-_116418056 1.386 NM_002313
ABLIM1
actin binding LIM protein 1
chr15_+_55611132 1.381 NM_004855
PIGB
phosphatidylinositol glycan anchor biosynthesis, class B
chr5_-_140013285 1.379 NM_001040021
NM_001174104
NM_001174105
CD14


CD14 molecule


chr10_+_82167584 1.370 NM_001243779
C10orf58
chromosome 10 open reading frame 58
chr4_-_16900028 1.358 LDB2
LIM domain binding 2
chr2_+_169929009 1.341 NM_001142270
DHRS9
dehydrogenase/reductase (SDR family) member 9
chr15_+_55611405 1.315 PIGB
phosphatidylinositol glycan anchor biosynthesis, class B
chr2_+_12857885 1.302 TRIB2
tribbles homolog 2 (Drosophila)
chr19_-_22379752 1.293 NM_001001411
ZNF676
zinc finger protein 676
chr3_-_149051258 1.277 NM_001184723
NM_138786
TM4SF18

transmembrane 4 L six family member 18

chr3_+_132036210 1.261 NM_001099
NM_001134194
ACPP

acid phosphatase, prostate

chr4_-_16900348 1.261 NM_001130834
NM_001290
LDB2

LIM domain binding 2

chr11_-_2152960 1.255 IGF2
insulin-like growth factor 2 (somatomedin A)
chr9_-_14398981 1.244 NM_001190738
NFIB
nuclear factor I/B
chr3_+_20081523 1.231 NM_003884
KAT2B
K(lysine) acetyltransferase 2B
chr17_+_67498391 1.215 MAP2K6
mitogen-activated protein kinase kinase 6
chr10_-_116286661 1.213 NM_006720
ABLIM1
actin binding LIM protein 1
chr4_-_101439071 1.212 NM_001159694
NM_016242
EMCN

endomucin

chr8_-_124749573 1.195 NM_001003954
NM_004306
ANXA13

annexin A13

chr15_+_57511616 1.195 NM_207040
TCF12
transcription factor 12
chr10_-_97200895 1.155 NM_001034954
NM_001034955
NM_001034956
NM_001034957
NM_006434
SORBS1




sorbin and SH3 domain containing 1




chr8_-_17579729 1.146 NM_001001931
MTUS1
microtubule associated tumor suppressor 1
chr4_+_41540187 1.145 LIMCH1
LIM and calponin homology domains 1
chr8_+_7738725 1.132 NM_001081551
DEFB103A
DEFB103B
defensin, beta 103A
defensin, beta 103B
chr17_-_67138013 1.127 NM_080284
ABCA6
ATP-binding cassette, sub-family A (ABC1), member 6
chr19_+_58280996 1.113 NM_001077426
NM_001204814
NM_017652
ZNF586


zinc finger protein 586


chrX_-_24045302 1.090 NM_030624
KLHL15
kelch-like 15 (Drosophila)
chr17_-_15973760 1.088 NCOR1
nuclear receptor corepressor 1
chr4_+_41540320 1.085 LIMCH1
LIM and calponin homology domains 1
chr3_-_160101443 1.079 NM_001190242
IFT80
intraflagellar transport 80 homolog (Chlamydomonas)
chr11_-_33891485 1.069 NM_001142315
LMO2
LIM domain only 2 (rhombotin-like 1)
chr6_-_2971981 1.066 SERPINB6
serpin peptidase inhibitor, clade B (ovalbumin), member 6
chr14_+_65877309 1.063 NM_004480
NM_178155
NM_178156
FUT8


fucosyltransferase 8 (alpha (1,6) fucosyltransferase)


chr13_-_20356788 1.062 PSPC1
paraspeckle component 1
chr9_-_111775721 1.053 NM_003798
CTNNAL1
catenin (cadherin-associated protein), alpha-like 1
chr12_+_79258517 1.048 SYT1
synaptotagmin I
chr14_-_73453651 1.048 NM_178441
ZFYVE1
zinc finger, FYVE domain containing 1
chr2_+_216176678 1.047 NM_004044
ATIC
5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
chr7_+_104681378 1.043 MLL5
myeloid/lymphoid or mixed-lineage leukemia 5 (trithorax homolog, Drosophila)
chr2_-_190627923 1.042 NM_022353
OSGEPL1
O-sialoglycoprotein endopeptidase-like 1
chr17_-_56358118 1.032 MPO
myeloperoxidase
chr13_-_20357125 1.028 NM_001042414
PSPC1
paraspeckle component 1
chr19_+_39155209 1.027


chr4_+_26585545 1.023 NM_018317
TBC1D19
TBC1 domain family, member 19
chr19_+_58281049 1.016 ZNF586
zinc finger protein 586
chr11_+_62104773 1.010 NM_001083926
NM_025080
ASRGL1

asparaginase like 1

chr8_-_7287869 1.009 NM_001081551
DEFB103A
DEFB103B
defensin, beta 103A
defensin, beta 103B
chr9_-_16870719 0.999 NM_017637
BNC2
basonuclin 2
chr8_-_95274540 0.981 NM_005261
NM_181702
GEM

GTP binding protein overexpressed in skeletal muscle

chr11_+_94822937 0.974 NM_015036
ENDOD1
endonuclease domain containing 1
chr5_+_61874561 0.974 NM_181506
LRRC70
leucine rich repeat containing 70
chr6_-_79675672 0.971 PHIP
pleckstrin homology domain interacting protein
chr17_+_7384720 0.966 NM_001102614
SLC35G6
solute carrier family 35, member G6
chr3_-_114343052 0.961 NM_001164347
ZBTB20
zinc finger and BTB domain containing 20
chr16_-_89831445 0.959 FANCA
Fanconi anemia, complementation group A
chr3_-_151987332 0.958 LOC401093
uncharacterized LOC401093
chr1_+_66999805 0.949 NM_032291
SGIP1
SH3-domain GRB2-like (endophilin) interacting protein 1
chr2_+_38893051 0.949 NM_138801
GALM
galactose mutarotase (aldose 1-epimerase)
chr20_-_45927496 0.936 ZMYND8
zinc finger, MYND-type containing 8
chr22_+_19938459 0.935 NM_001135161
COMT
catechol-O-methyltransferase
chr2_+_85804689 0.928 VAMP8
vesicle-associated membrane protein 8 (endobrevin)
chr19_-_39322411 0.925 NM_001398
ECH1
enoyl CoA hydratase 1, peroxisomal
chr3_-_46506342 0.923 NM_002343
LTF
lactotransferrin
chr17_-_71088831 0.916 SLC39A11
solute carrier family 39 (metal ion transporter), member 11
chr10_-_105238996 0.910 NM_001129742
CALHM3
calcium homeostasis modulator 3
chr13_-_20357081 0.905 PSPC1
paraspeckle component 1
chr1_+_210406194 0.905 NM_019605
SERTAD4
SERTA domain containing 4
chr3_-_196065243 0.901 NM_001204897
NM_001204898
NM_138461
TM4SF19


transmembrane 4 L six family member 19


chr3_-_105421044 0.890 CBLB
Cas-Br-M (murine) ecotropic retroviral transforming sequence b
chr2_+_66666445 0.888 MEIS1
Meis homeobox 1
chr7_-_120498128 0.888 NM_012338
TSPAN12
tetraspanin 12
chr15_+_96876568 0.878 NM_001145157
NR2F2
nuclear receptor subfamily 2, group F, member 2
chr1_-_53387339 0.878 ECHDC2
enoyl CoA hydratase domain containing 2
chr10_+_119301955 0.876 NM_001165924
NM_004098
EMX2

empty spiracles homeobox 2

chr2_+_85804613 0.876 NM_003761
VAMP8
vesicle-associated membrane protein 8 (endobrevin)
chr1_+_66458389 0.876 NM_001037340
PDE4B
phosphodiesterase 4B, cAMP-specific
chr20_-_34117447 0.871 NM_001145350
C20orf173
chromosome 20 open reading frame 173
chrX_-_119709618 0.870 NM_003588
CUL4B
cullin 4B
chr1_+_26872306 0.858 RPS6KA1
ribosomal protein S6 kinase, 90kDa, polypeptide 1
chr17_-_62084282 0.857 NM_000873
ICAM2
intercellular adhesion molecule 2
chr11_+_63997941 0.848 DNAJC4
DnaJ (Hsp40) homolog, subfamily C, member 4
chr12_+_79257772 0.845 NM_001135805
SYT1
synaptotagmin I
chr19_-_49865638 0.845 NM_003598
TEAD2
TEA domain family member 2
chr18_-_22931970 0.844 ZNF521
zinc finger protein 521
chr13_-_78549663 0.841 NM_000115
EDNRB
endothelin receptor type B
chr14_+_102276125 0.840 NM_002719
NM_178586
NM_178587
PPP2R5C


protein phosphatase 2, regulatory subunit B', gamma


chr2_+_48757292 0.839 NM_001198595
NM_006873
STON1

stonin 1

chr9_+_131580719 0.838 NM_004435
ENDOG
endonuclease G
chr7_+_80267922 0.836 CD36
CD36 molecule (thrombospondin receptor)
chr21_+_46020496 0.831 NM_198689
KRTAP10-7
keratin associated protein 10-7
chr1_+_223889253 0.830 NM_001146068
CAPN2
calpain 2, (m/II) large subunit
chr5_-_125930604 0.830 NM_001182
NM_001201377
NM_001202404
ALDH7A1


aldehyde dehydrogenase 7 family, member A1


chr1_-_1677430 0.827 NM_001199787
NM_182838
SLC35E2B
SLC35E2

solute carrier family 35, member E2B
solute carrier family 35, member E2

chr7_-_131833385 0.825 PLXNA4
plexin A4
chr18_-_53303129 0.815 NM_001243226
TCF4
transcription factor 4
chr1_-_24151932 0.810 NM_000191
NM_001166059
HMGCL

3-hydroxymethyl-3-methylglutaryl-CoA lyase

chr3_+_127317212 0.808 NM_004526
MCM2
minichromosome maintenance complex component 2
chr20_+_11871364 0.803 NM_181443
BTBD3
BTB (POZ) domain containing 3
chr2_+_216176808 0.801 ATIC
5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
chr14_+_66974124 0.797 NM_001024218
NM_020806
GPHN

gephyrin

chr17_-_1248346 0.795 PAFAH1B1
platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
chr2_-_128433330 0.794 LIMS2
LIM and senescent cell antigen-like domains 2
chr2_+_138721807 0.790 NM_001024074
NM_001024075
NM_006895
HNMT


histamine N-methyltransferase


chr1_-_24151845 0.782 HMGCL
3-hydroxymethyl-3-methylglutaryl-CoA lyase
chr10_-_126849010 0.781 CTBP2
C-terminal binding protein 2
chr12_-_124068864 0.780


chr5_+_139028483 0.779 CXXC5
CXXC finger protein 5
chr12_+_118454505 0.779 NM_001130112
NM_001206801
NM_007370
NM_181578
RFC5



replication factor C (activator 1) 5, 36.5kDa



chr9_-_14313899 0.776 NFIB
nuclear factor I/B
chr19_-_36391448 0.774 NM_139239
NFKBID
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, delta
chr5_+_37379382 0.772 WDR70
WD repeat domain 70
chr2_+_31456879 0.765 NM_014600
EHD3
EH-domain containing 3
chr1_-_68516311 0.764 NM_004675
DIRAS3
DIRAS family, GTP-binding RAS-like 3
chr6_+_153019029 0.761 NM_025107
MYCT1
myc target 1
chr19_-_14260728 0.759 LPHN1
latrophilin 1
chr3_+_183165402 0.754 LOC100505687
uncharacterized LOC100505687
chr15_-_69113089 0.748 ANP32A
acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
chr16_-_28550324 0.747 NM_001042483
NM_012385
NUPR1

nuclear protein, transcriptional regulator, 1

chr12_-_96429397 0.746 LTA4H
leukotriene A4 hydrolase
chr22_-_19435727 0.745 NM_001166242
NM_173793
C22orf39

chromosome 22 open reading frame 39

chr16_-_28550227 0.739 NUPR1
nuclear protein, transcriptional regulator, 1
chr6_+_16238780 0.735 NM_006877
GMPR
guanosine monophosphate reductase
chr5_+_37379392 0.730 NM_018034
WDR70
WD repeat domain 70
chr19_-_58485901 0.729 NM_152474
C19orf18
chromosome 19 open reading frame 18
chr1_+_109102970 0.729 NM_001010883
FAM102B
family with sequence similarity 102, member B
chr2_+_219246751 0.728 NM_000578
SLC11A1
solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1
chr17_+_67410825 0.726 NM_002758
MAP2K6
mitogen-activated protein kinase kinase 6
chr17_-_39968450 0.717 NM_006455
LEPREL4
leprecan-like 4
chr8_+_42249383 0.716 VDAC3
voltage-dependent anion channel 3
chr4_-_186733372 0.714 NM_003603
NM_001145670
SORBS2

sorbin and SH3 domain containing 2

chr5_-_42811959 0.713 NM_001085486
NM_001093726
NM_005410
SEPP1


selenoprotein P, plasma, 1


chr10_+_82168206 0.712 NM_001243780
NM_001243781
NM_032333
C10orf58


chromosome 10 open reading frame 58


chr4_+_170581212 0.708 NM_001243374
CLCN3
chloride channel 3
chrX_-_117251302 0.706 NM_001168301
KLHL13
kelch-like 13 (Drosophila)
chr14_+_37667116 0.704 NM_001195296
NM_001195297
NM_138731
MIPOL1


mirror-image polydactyly 1


chr7_-_21985421 0.702 NM_001127370
NM_001127371
NM_018719
CDCA7L


cell division cycle associated 7-like


chr11_-_62472901 0.702


chr8_-_95274520 0.699 GEM
GTP binding protein overexpressed in skeletal muscle
chr4_-_186578122 0.695 NM_001145674
NM_001145675
SORBS2

sorbin and SH3 domain containing 2


Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.13 3.44e-03 GO:0044237 cellular metabolic process
1.21 4.36e-03 GO:0034641 cellular nitrogen compound metabolic process
1.20 4.59e-03 GO:0006807 nitrogen compound metabolic process
1.07 4.62e-03 GO:0009987 cellular process
1.96 7.50e-03 GO:0022411 cellular component disassembly
1.96 7.50e-03 GO:0071845 cellular component disassembly at cellular level
1.11 1.27e-02 GO:0008152 metabolic process
1.20 4.51e-02 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.09 2.51e-07 GO:0044424 intracellular part
1.08 4.62e-07 GO:0005622 intracellular
1.11 1.08e-05 GO:0043231 intracellular membrane-bounded organelle
1.11 1.47e-05 GO:0043227 membrane-bounded organelle
1.11 1.63e-05 GO:0005737 cytoplasm
1.09 7.21e-05 GO:0043229 intracellular organelle
1.09 9.51e-05 GO:0043226 organelle
1.12 2.09e-03 GO:0044444 cytoplasmic part
1.12 5.24e-03 GO:0005634 nucleus
1.21 3.77e-02 GO:0044428 nuclear part

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.05 4.27e-02 GO:0005488 binding