Motif ID: CACAGUG

Z-value: 0.926


Mature miRNA associated with seed CACAGUG:

NamemiRBase Accession
hsa-miR-128 MIMAT0000424



Activity profile for motif CACAGUG.

activity profile for motif CACAGUG


Sorted Z-values histogram for motif CACAGUG

Sorted Z-values for motif CACAGUG



Network of associatons between targets according to the STRING database.



First level regulatory network of CACAGUG

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr8_-_22549901 4.574 NM_001199880
 EGR3
early growth response 3
chr8_-_22550708 4.519 NM_004430
 EGR3
early growth response 3
chr8_-_22550057 4.476 NM_001199881
 EGR3
early growth response 3
chr2_+_7057471 3.428 NM_014746
 RNF144A
ring finger protein 144A
chr9_-_134151905 3.387 NM_033387
 FAM78A
family with sequence similarity 78, member A
chr6_+_136172802 3.151 NM_018945
 PDE7B
phosphodiesterase 7B
chr6_-_13408368 3.097 NM_001242630
 GFOD1
glucose-fructose oxidoreductase domain containing 1
chr1_+_221052735 2.958 NM_021958
 HLX
H2.0-like homeobox
chr1_-_92371558 2.932 NM_001195684
 TGFBR3
transforming growth factor, beta receptor III
chr1_-_92351613 2.798 NM_001195683
NM_003243
 TGFBR3

transforming growth factor, beta receptor III

chr19_+_45971249 2.703 NM_001114171
NM_006732
 FOSB

FBJ murine osteosarcoma viral oncogene homolog B

chr10_-_131762017 2.600 NM_001005463
 EBF3
early B-cell factor 3
chr8_-_127570710 2.537 NM_174911
 FAM84B
family with sequence similarity 84, member B
chr14_+_56584854 2.530 NM_021255
 PELI2
pellino homolog 2 (Drosophila)
chr7_-_27183225 2.482 NM_019102
 HOXA5
homeobox A5
chr18_+_20715726 2.341 NM_001100619
 CABLES1
Cdk5 and Abl enzyme substrate 1
chr18_+_20735788 2.324 NM_138375
 CABLES1
Cdk5 and Abl enzyme substrate 1
chr1_-_154474524 2.310 NM_001010846
 SHE
Src homology 2 domain containing E
chr10_-_81205091 2.306 NM_153367
 ZCCHC24
zinc finger, CCHC domain containing 24
chr22_-_28197469 2.250 NM_002430
 MN1
meningioma (disrupted in balanced translocation) 1

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 24 entries
enrichment   p-value GO term description
2.93 1.80e-03 GO:0007389 pattern specification process
2.54 2.34e-02 GO:0000122 negative regulation of transcription from RNA polymerase II promoter
2.48 4.96e-02 GO:0007264 small GTPase mediated signal transduction
2.42 4.81e-03 GO:0045892 negative regulation of transcription, DNA-dependent
2.37 7.44e-03 GO:0051253 negative regulation of RNA metabolic process
2.33 2.86e-03 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
2.29 8.74e-03 GO:0010629 negative regulation of gene expression
2.25 1.20e-02 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.23 8.10e-03 GO:0010558 negative regulation of macromolecule biosynthetic process
2.22 5.04e-03 GO:0009790 embryo development
2.22 1.57e-02 GO:0051172 negative regulation of nitrogen compound metabolic process
2.20 8.50e-03 GO:0031327 negative regulation of cellular biosynthetic process
2.15 1.37e-02 GO:0009890 negative regulation of biosynthetic process
1.90 3.20e-02 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.77 1.26e-02 GO:0009966 regulation of signal transduction
1.52 1.55e-02 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.44 9.27e-03 GO:0031323 regulation of cellular metabolic process
1.43 7.28e-03 GO:0023052 signaling
1.43 2.97e-02 GO:0007165 signal transduction
1.40 1.92e-02 GO:0019222 regulation of metabolic process

Gene overrepresentation in compartment category:

Showing 1 to 6 of 6 entries
enrichment   p-value GO term description
5.69 1.85e-02 GO:0044309 neuron spine
1.27 1.89e-02 GO:0005634 nucleus
1.18 3.05e-02 GO:0043231 intracellular membrane-bounded organelle
1.18 3.35e-02 GO:0043227 membrane-bounded organelle
1.15 1.77e-03 GO:0005622 intracellular
1.14 9.55e-03 GO:0044424 intracellular part

Gene overrepresentation in function category:

Showing 1 to 12 of 12 entries
enrichment   p-value GO term description
11.11 2.23e-02 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity
5.27 4.77e-02 GO:0004879 ligand-dependent nuclear receptor activity
3.64 2.37e-02 GO:0060090 binding, bridging
2.54 2.57e-02 GO:0016563 transcription activator activity
2.49 4.96e-02 GO:0016564 transcription repressor activity
1.94 1.47e-03 GO:0030528 transcription regulator activity
1.84 1.48e-02 GO:0001071 nucleic acid binding transcription factor activity
1.84 1.48e-02 GO:0003700 sequence-specific DNA binding transcription factor activity
1.41 1.87e-03 GO:0046872 metal ion binding
1.40 2.48e-03 GO:0043167 ion binding
1.39 3.48e-03 GO:0043169 cation binding
1.23 1.07e-02 GO:0005515 protein binding