Motif ID: CUACAGU

Z-value: 0.489


Mature miRNA associated with seed CUACAGU:

NamemiRBase Accession
hsa-miR-139-5p MIMAT0000250



Activity profile for motif CUACAGU.

activity profile for motif CUACAGU


Sorted Z-values histogram for motif CUACAGU

Sorted Z-values for motif CUACAGU



Network of associatons between targets according to the STRING database.



First level regulatory network of CUACAGU

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr8_+_17354562 0.704 NM_001008539
 SLC7A2
solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
chr8_+_17396285 0.688 NM_001164771
NM_003046
 SLC7A2

solute carrier family 7 (cationic amino acid transporter, y+ system), member 2

chr12_+_102271082 0.613 NM_018370
 DRAM1
DNA-damage regulated autophagy modulator 1
chr4_-_120549115 0.554 NM_033437
 PDE5A
phosphodiesterase 5A, cGMP-specific
chr5_-_59189620 0.534 NM_001104631
 PDE4D
phosphodiesterase 4D, cAMP-specific
chr1_+_145209067 0.519 NM_203458
 NOTCH2NL
notch 2 N-terminal like
chr7_-_92465929 0.506 NM_001145306
 CDK6
cyclin-dependent kinase 6
chr7_-_115670828 0.482 NM_001018058
NM_012252
 TFEC

transcription factor EC

chr5_-_58882274 0.475 NM_006203
 PDE4D
phosphodiesterase 4D, cAMP-specific
chr7_-_92463211 0.472 NM_001259
 CDK6
cyclin-dependent kinase 6
chr5_-_59783885 0.469 NM_001165899
 PDE4D
phosphodiesterase 4D, cAMP-specific
chr5_-_58571916 0.463 NM_001197220
 PDE4D
phosphodiesterase 4D, cAMP-specific
chr5_-_59064437 0.455 NM_001197218
 PDE4D
phosphodiesterase 4D, cAMP-specific
chr5_-_58295758 0.451 NM_001197223
 PDE4D
phosphodiesterase 4D, cAMP-specific
chr5_-_58334936 0.428 NM_001197221
NM_001197222
 PDE4D

phosphodiesterase 4D, cAMP-specific

chr5_-_58652671 0.418 NM_001197219
 PDE4D
phosphodiesterase 4D, cAMP-specific
chr4_-_120549827 0.401 NM_001083
 PDE5A
phosphodiesterase 5A, cGMP-specific
chr11_-_128457452 0.384 NM_001143820
 ETS1
v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)
chr16_-_75590107 0.372 NM_001077416
NM_001077418
NM_001077419
 TMEM231


transmembrane protein 231


chr7_-_139477437 0.372 NM_001113239
NM_022740
 HIPK2

homeodomain interacting protein kinase 2


Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 21 entries
enrichment   p-value GO term description
6.45 4.40e-02 GO:0021987 cerebral cortex development
5.62 1.61e-02 GO:0021543 pallium development
4.19 4.72e-02 GO:0021537 telencephalon development
2.55 3.53e-02 GO:0051603 proteolysis involved in cellular protein catabolic process
2.50 4.87e-02 GO:0044257 cellular protein catabolic process
2.22 2.49e-02 GO:0044265 cellular macromolecule catabolic process
2.12 4.60e-02 GO:0048666 neuron development
2.08 3.40e-02 GO:0030030 cell projection organization
1.91 2.49e-02 GO:0006351 transcription, DNA-dependent
1.50 1.79e-02 GO:0044267 cellular protein metabolic process
1.48 6.65e-04 GO:0060255 regulation of macromolecule metabolic process
1.47 6.62e-04 GO:0080090 regulation of primary metabolic process
1.44 4.85e-05 GO:0044260 cellular macromolecule metabolic process
1.44 2.53e-03 GO:0031323 regulation of cellular metabolic process
1.43 8.99e-04 GO:0019222 regulation of metabolic process
1.35 2.92e-03 GO:0043170 macromolecule metabolic process
1.30 1.58e-03 GO:0044237 cellular metabolic process
1.25 1.67e-02 GO:0050794 regulation of cellular process
1.25 3.72e-02 GO:0044238 primary metabolic process
1.22 4.37e-02 GO:0050789 regulation of biological process

Gene overrepresentation in compartment category:

Showing 1 to 4 of 4 entries
enrichment   p-value GO term description
1.25 2.40e-02 GO:0005634 nucleus
1.15 4.50e-04 GO:0005622 intracellular
1.15 4.55e-02 GO:0043226 organelle
1.14 1.63e-03 GO:0044424 intracellular part

Gene overrepresentation in function category:

Showing 1 to 5 of 5 entries
enrichment   p-value GO term description
15.73 2.57e-02 GO:0004690 cyclic nucleotide-dependent protein kinase activity
2.45 2.23e-02 GO:0016563 transcription activator activity
1.75 2.29e-02 GO:0030528 transcription regulator activity
1.73 4.51e-02 GO:0001071 nucleic acid binding transcription factor activity
1.73 4.51e-02 GO:0003700 sequence-specific DNA binding transcription factor activity