Motif ID: CUX2.p2

Z-value: 0.303


Transcription factors associated with CUX2.p2:

Gene SymbolEntrez IDGene Name
CUX2 23316 cut-like homeobox 2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.p-valuePlot
CUX2chr12_+_111471827-0.087.0e-01Click!


Activity profile for motif CUX2.p2.

activity profile for motif CUX2.p2


Sorted Z-values histogram for motif CUX2.p2

Sorted Z-values for motif CUX2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of CUX2.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr10_-_116392099 0.818 ABLIM1
actin binding LIM protein 1
chr7_+_80231503 0.380 NM_001001547
CD36
CD36 molecule (thrombospondin receptor)
chr2_+_132480063 0.368 NM_013310
C2orf27A
chromosome 2 open reading frame 27A
chr10_+_69869249 0.291 NM_032578
MYPN
myopalladin
chr22_+_25591072 0.267 KIAA1671
KIAA1671
chr19_-_58864820 0.226 NM_130786
A1BG
alpha-1-B glycoprotein
chr11_+_22689653 0.224 NM_177553
GAS2
growth arrest-specific 2
chr3_-_15798057 0.213 NM_001195099
ANKRD28
ankyrin repeat domain 28
chr17_-_46687925 0.188 HOXB7
homeobox B7
chr13_+_53035227 0.173 CKAP2
cytoskeleton associated protein 2
chrX_-_117119282 0.169 NM_001168299
KLHL13
kelch-like 13 (Drosophila)
chr4_+_41700736 0.165 LIMCH1
LIM and calponin homology domains 1
chr5_+_36606667 0.160 SLC1A3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chrX_-_106362050 0.160 NM_001171080
NM_018301
RBM41

RNA binding motif protein 41

chr3_+_159557745 0.156 SCHIP1
schwannomin interacting protein 1
chr13_-_46756291 0.156 LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr22_-_26961333 0.153 NM_001008566
TPST2
tyrosylprotein sulfotransferase 2
chr17_-_8424217 0.152 MYH10
myosin, heavy chain 10, non-muscle
chr9_-_5304579 0.145 NM_005059
NM_134441
RLN2

relaxin 2

chr3_+_159557649 0.136 NM_001197109
SCHIP1
schwannomin interacting protein 1
chr17_-_46688362 0.133 NM_004502
HOXB7
homeobox B7
chr13_-_46756295 0.127 LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr8_+_77593522 0.122 ZFHX4
zinc finger homeobox 4
chr3_-_15839674 0.113 NM_001195098
ANKRD28
ankyrin repeat domain 28
chr7_-_144107319 0.111 NM_001080413
NOBOX
NOBOX oogenesis homeobox
chr14_+_21457964 0.109 NM_001029991
NM_022734
METTL17

methyltransferase like 17

chr1_+_104159953 0.109 NM_000699
AMY2A
amylase, alpha 2A (pancreatic)
chr5_+_36606456 0.108 NM_001166696
NM_004172
SLC1A3

solute carrier family 1 (glial high affinity glutamate transporter), member 3

chr5_-_43412417 0.106 NM_148672
CCL28
chemokine (C-C motif) ligand 28
chr7_+_80275634 0.104 NM_001127443
NM_001127444
CD36

CD36 molecule (thrombospondin receptor)

chr12_-_54653369 0.101 NM_001127321
CBX5
chromobox homolog 5
chr8_-_17752847 0.096 NM_147203
NM_201553
NM_004467
NM_201552
FGL1



fibrinogen-like 1



chr1_+_12976449 0.091 NM_001012276
PRAMEF8
PRAMEF7
PRAME family member 8
PRAME family member 7
chr12_-_54653317 0.090 NM_001127322
CBX5
chromobox homolog 5
chr8_+_18248754 0.089 NM_000015
NAT2
N-acetyltransferase 2 (arylamine N-acetyltransferase)
chr4_-_72649734 0.087 NM_000583
GC
group-specific component (vitamin D binding protein)
chr2_+_169926084 0.082 DHRS9
dehydrogenase/reductase (SDR family) member 9
chr12_+_74931550 0.081 NM_001136262
ATXN7L3B
ataxin 7-like 3B
chr12_-_7818467 0.078 NM_001644
APOBEC1
apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1
chr5_-_94224601 0.077 MCTP1
multiple C2 domains, transmembrane 1
chr12_+_14538232 0.076 ATF7IP
activating transcription factor 7 interacting protein
chr3_+_134514044 0.076 NM_004441
EPHB1
EPH receptor B1
chr8_-_120651019 0.074 NM_001040092
NM_001130863
NM_006209
ENPP2


ectonucleotide pyrophosphatase/phosphodiesterase 2


chr6_+_116850175 0.072 NM_153036
FAM26D
family with sequence similarity 26, member D
chr2_-_192016293 0.070 NM_001243835
STAT4
signal transducer and activator of transcription 4
chr1_-_17308072 0.068 NM_001135247
NM_017459
MFAP2

microfibrillar-associated protein 2

chrX_+_123480131 0.068 NM_001114937
NM_002351
SH2D1A

SH2 domain containing 1A

chr17_-_46688279 0.068 HOXB7
homeobox B7
chr8_-_133459508 0.066 NM_001204824
KCNQ3
potassium voltage-gated channel, KQT-like subfamily, member 3
chr1_-_146068244 0.066 NM_001101663
NBPF11
NBPF24
neuroblastoma breakpoint family, member 11
neuroblastoma breakpoint family, member 24
chr12_+_131438451 0.064 NM_198827
GPR133
G protein-coupled receptor 133
chr13_-_36429798 0.064 NM_001195415
NM_001195416
NM_001195430
DCLK1


doublecortin-like kinase 1


chr13_+_31309644 0.064 NM_001629
ALOX5AP
arachidonate 5-lipoxygenase-activating protein
chr9_-_130497617 0.064 NM_001085347
NM_001134430
NM_001134431
NM_001252018
NM_001252021
NM_001252023
NM_130459
TOR2A






torsin family 2, member A






chr1_-_147610080 0.062 NM_001101663
NBPF11
NBPF24
neuroblastoma breakpoint family, member 11
neuroblastoma breakpoint family, member 24
chr9_-_130497551 0.060 TOR2A
torsin family 2, member A
chr7_+_150413597 0.060 NM_001199577
NM_130759
GIMAP1-GIMAP5
GIMAP1
GIMAP1-GIMAP5 readthrough
GTPase, IMAP family member 1
chr22_-_37098620 0.059 NM_006078
CACNG2
calcium channel, voltage-dependent, gamma subunit 2
chr1_+_117297056 0.058 NM_001767
CD2
CD2 molecule
chr3_-_93692898 0.057 NM_000313
PROS1
protein S (alpha)
chr1_+_206730456 0.056 NM_182665
RASSF5
Ras association (RalGDS/AF-6) domain family member 5
chr1_+_198608216 0.056 PTPRC
protein tyrosine phosphatase, receptor type, C
chr5_+_88185090 0.056


chr11_+_92085261 0.055 NM_001008781
FAT3
FAT tumor suppressor homolog 3 (Drosophila)
chr17_-_79875995 0.055 SIRT7
sirtuin 7
chr20_+_31755882 0.053 NM_080574
BPIFA2
BPI fold containing family A, member 2
chr21_-_31538970 0.052 NM_012131
CLDN17
claudin 17
chr6_+_32709162 0.051 NM_020056
HLA-DQA1
HLA-DQA2
major histocompatibility complex, class II, DQ alpha 1
major histocompatibility complex, class II, DQ alpha 2
chr17_+_67498391 0.050 MAP2K6
mitogen-activated protein kinase kinase 6
chrX_+_30248552 0.048 NM_002365
MAGEB3
melanoma antigen family B, 3
chr6_-_27799304 0.044 NM_003541
HIST1H4A
HIST1H4F
HIST1H4K
HIST1H4J
histone cluster 1, H4a
histone cluster 1, H4f
histone cluster 1, H4k
histone cluster 1, H4j
chr3_+_100238063 0.042 TMEM45A
transmembrane protein 45A
chr13_-_46756326 0.042 NM_002298
LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr1_+_57320442 0.040 NM_000562
C8A
complement component 8, alpha polypeptide
chr9_+_27109138 0.038 NM_000459
TEK
TEK tyrosine kinase, endothelial
chr15_+_38227456 0.038 NM_152453
TMCO5A
transmembrane and coiled-coil domains 5A
chr3_+_46919235 0.037 NM_000316
PTH1R
parathyroid hormone 1 receptor
chr8_-_86290333 0.036 NM_001128829
NM_001128830
NM_001128831
NM_001738
CA1



carbonic anhydrase I



chr4_+_176987148 0.035 WDR17
WD repeat domain 17
chr20_-_17539480 0.034 NM_001161705
BFSP1
beaded filament structural protein 1, filensin
chr1_-_186430216 0.032 NM_002597
PDC
phosducin
chr1_+_198608136 0.032 NM_002838
NM_080921
NM_080923
PTPRC


protein tyrosine phosphatase, receptor type, C


chr9_-_21228132 0.031 NM_021268
IFNA17
interferon, alpha 17
chr17_-_79876027 0.028 SIRT7
sirtuin 7
chr17_+_56315786 0.027 NM_001160102
NM_006151
LPO

lactoperoxidase

chr19_+_44645728 0.027 ZNF234
zinc finger protein 234
chr11_+_62037629 0.027 NM_002411
SCGB2A2
secretoglobin, family 2A, member 2
chr4_+_71296208 0.027 NM_001145006
MUC7
mucin 7, secreted
chr4_+_71091787 0.026 NM_152997
C4orf7
chromosome 4 open reading frame 7
chr14_-_74025643 0.026 NM_001220484
NM_203309
HEATR4

HEAT repeat containing 4

chr12_-_10562744 0.025 NM_001199805
KLRC4-KLRK1
KLRC4-KLRK1 readthrough
chr20_-_1309809 0.025 NM_080489
SDCBP2
syndecan binding protein (syntenin) 2
chr5_+_140529619 0.024 NM_018939
PCDHB6
protocadherin beta 6
chr12_-_10978867 0.023 NM_023921
TAS2R10
taste receptor, type 2, member 10
chr2_-_61245363 0.023 NM_144709
PUS10
pseudouridylate synthase 10
chr16_+_12058963 0.022 NM_001192
TNFRSF17
tumor necrosis factor receptor superfamily, member 17
chr1_-_104238785 0.022 NM_004038
NM_001008218
NM_001008219
AMY1A
AMY1B
AMY1C
amylase, alpha 1A (salivary)
amylase, alpha 1B (salivary)
amylase, alpha 1C (salivary)
chr12_+_52056547 0.019 NM_001177984
SCN8A
sodium channel, voltage gated, type VIII, alpha subunit
chr4_-_2230957 0.017 NM_181808
POLN
polymerase (DNA directed) nu
chrX_-_118726852 0.016 NM_001173488
NKRF
NFKB repressing factor
chr20_-_22566092 0.016 NM_153675
FOXA2
forkhead box A2
chr7_-_23509972 0.016 NM_006547
IGF2BP3
insulin-like growth factor 2 mRNA binding protein 3
chr1_-_149399159 0.016 NM_001024599
HIST2H2BF
histone cluster 2, H2bf
chr5_+_126984712 0.015 NM_001048252
CTXN3
cortexin 3
chr8_-_108510094 0.015 NM_001146
NM_001199859
ANGPT1

angiopoietin 1

chr14_+_56078735 0.014 KTN1
kinectin 1 (kinesin receptor)
chr3_+_119500866 0.013 NR1I2
nuclear receptor subfamily 1, group I, member 2
chr7_-_121944485 0.012 NM_001024613
NM_001160264
FEZF1

FEZ family zinc finger 1

chr5_+_140247767 0.011 NM_018902
NM_031861
PCDHA11

protocadherin alpha 11

chr4_+_71587674 0.011 NM_001037442
NM_014961
RUFY3

RUN and FYVE domain containing 3

chr8_+_17829848 0.010 PCM1
pericentriolar material 1
chr12_+_6554032 0.010 NM_001242
CD27
CD27 molecule
chr2_-_20512016 0.010 PUM2
pumilio homolog 2 (Drosophila)
chr20_-_44298877 0.009 NM_147197
WFDC11
WAP four-disulfide core domain 11
chr4_+_169418167 0.009 NM_001166108
NM_016081
PALLD

palladin, cytoskeletal associated protein

chr3_-_126277757 0.009 NM_152533
C3orf22
chromosome 3 open reading frame 22
chrX_+_30260056 0.009 NM_002367
MAGEB4
melanoma antigen family B, 4
chr12_+_26126687 0.009 NM_001164747
RASSF8
Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
chr17_-_2996289 0.009 NM_002548
OR1D2
olfactory receptor, family 1, subfamily D, member 2
chr8_+_11188494 0.008 NM_054028
SLC35G5
solute carrier family 35, member G5
chr11_+_60467046 0.008 NM_031457
MS4A8B
membrane-spanning 4-domains, subfamily A, member 8B
chr18_-_70532933 0.007 NM_138999
NETO1
neuropilin (NRP) and tolloid (TLL)-like 1
chr11_-_47736896 0.007 NM_024783
AGBL2
ATP/GTP binding protein-like 2
chr4_+_166131170 0.006 NM_001161521
NM_001161522
KLHL2

kelch-like 2, Mayven (Drosophila)

chr6_+_159309618 0.006 NM_001195032
C6orf99
chromosome 6 open reading frame 99
chrY_+_4924128 0.006 NM_032972
NM_032973
PCDH11X
PCDH11Y

protocadherin 11 X-linked
protocadherin 11 Y-linked

chr3_+_119500930 0.005 NR1I2
nuclear receptor subfamily 1, group I, member 2
chr22_-_40289793 0.005 NM_152512
ENTHD1
ENTH domain containing 1
chr2_+_219125737 0.005 NM_001077191
NM_001077194
NM_170699
GPBAR1


G protein-coupled bile acid receptor 1


chr12_-_11422640 0.005 NM_006249
PRB3
proline-rich protein BstNI subfamily 3
chr12_-_22089627 0.005 NM_005691
NM_020297
ABCC9

ATP-binding cassette, sub-family C (CFTR/MRP), member 9

chr11_+_117075682 0.005 TAGLN
transgelin
chr2_-_172291227 0.004 NM_024770
METTL8
methyltransferase like 8
chr4_+_187187117 0.004 NM_000128
F11
coagulation factor XI
chrY_-_26194115 0.003 NM_001003894
NM_001003895
NM_004680
NM_170723
CDY1B

CDY1

chromodomain protein, Y-linked, 1B

chromodomain protein, Y-linked, 1

chr14_+_88490893 0.003 LOC283587
uncharacterized LOC283587
chr8_+_17822093 0.002 PCM1
pericentriolar material 1
chr13_-_41556188 0.002 ELF1
E74-like factor 1 (ets domain transcription factor)
chr6_-_32160637 0.002 GPSM3
G-protein signaling modulator 3
chr6_+_129204285 0.002 NM_000426
NM_001079823
LAMA2

laminin, alpha 2

chr2_-_77749335 0.002 NM_001134745
NM_024993
LRRTM4

leucine rich repeat transmembrane neuronal 4

chr2_+_69201704 0.001 NM_019617
GKN1
gastrokine 1
chr7_-_36764000 0.001 NM_001177506
NM_001177507
NM_001637
AOAH


acyloxyacyl hydrolase (neutrophil)


chrX_-_13835313 0.001 NM_001001995
NM_001001996
NM_005278
GPM6B


glycoprotein M6B


chr4_-_47465719 0.001 COMMD8
COMM domain containing 8
chr5_+_60933635 0.001 NM_173667
C5orf64
chromosome 5 open reading frame 64
chr2_-_152830448 0.001 NM_001005747
CACNB4
calcium channel, voltage-dependent, beta 4 subunit
chr6_+_29426130 0.001 NM_030883
OR2H1
olfactory receptor, family 2, subfamily H, member 1
chrX_+_106171328 0.000 CLDN2
claudin 2

Gene Ontology Analysis

Nothing significant found in process category.

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
2.40 1.48e-02 GO:0005887 integral to plasma membrane
2.35 1.91e-02 GO:0031226 intrinsic to plasma membrane
1.91 2.94e-02 GO:0044459 plasma membrane part

Nothing significant found in function category.