Motif ID: ELK1,4_GABP{A,B1}.p3

Z-value: 1.911


Transcription factors associated with ELK1,4_GABP{A,B1}.p3:

Gene SymbolEntrez IDGene Name
ELK1 2002 ELK1, member of ETS oncogene family
ELK4 2005 ELK4, ETS-domain protein (SRF accessory protein 1)
GABPA 2551 GA binding protein transcription factor, alpha subunit 60kDa
GABPB1 2553 GA binding protein transcription factor, beta subunit 1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.p-valuePlot
GABPAchr21_+_27107671-0.519.1e-03Click!
ELK1chrX_-_475098640.349.9e-02Click!
ELK4chr1_-_205601999-0.272.0e-01Click!
GABPB1chr15_-_506472750.087.0e-01Click!


Activity profile for motif ELK1,4_GABP{A,B1}.p3.

activity profile for motif ELK1,4_GABP{A,B1}.p3


Sorted Z-values histogram for motif ELK1,4_GABP{A,B1}.p3

Sorted Z-values for motif ELK1,4_GABP{A,B1}.p3



Network of associatons between targets according to the STRING database.



First level regulatory network of ELK1,4_GABP{A,B1}.p3

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr9_+_35732629 3.454 CREB3
cAMP responsive element binding protein 3
chr11_+_46722316 3.051 NM_024741
ZNF408
zinc finger protein 408
chr9_+_35732498 2.712 CREB3
cAMP responsive element binding protein 3
chr12_-_6798619 2.406 NM_001039920
NM_001135734
ZNF384

zinc finger protein 384

chr19_+_58694444 2.369 ZNF274
zinc finger protein 274
chr11_+_46722564 2.345 NM_001184751
ZNF408
zinc finger protein 408
chr9_+_35732207 2.311 NM_006368
CREB3
cAMP responsive element binding protein 3
chr12_-_6798528 2.276 NM_133476
ZNF384
zinc finger protein 384
chr9_-_123691442 2.111 NM_001190945
TRAF1
TNF receptor-associated factor 1
chr2_+_109745996 2.084 NM_001099289
SH3RF3
SH3 domain containing ring finger 3
chr21_-_30365111 2.058 NM_015565
LTN1
listerin E3 ubiquitin protein ligase 1
chr10_-_79789290 2.041 NM_007055
POLR3A
polymerase (RNA) III (DNA directed) polypeptide A, 155kDa
chr16_+_31044849 2.027 STX4
syntaxin 4
chr16_+_31044881 1.993 NM_004604
STX4
syntaxin 4
chr1_+_101361688 1.953 SLC30A7
solute carrier family 30 (zinc transporter), member 7
chr19_+_58694381 1.813 NM_016324
NM_016325
NM_133502
ZNF274


zinc finger protein 274


chr6_-_32811773 1.736 NM_148919
PSMB8
proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional peptidase 7)
chr13_-_33760215 1.732 NM_001243466
NM_178007
STARD13

StAR-related lipid transfer (START) domain containing 13

chr19_+_38810461 1.728 NM_004823
KCNK6
potassium channel, subfamily K, member 6
chr1_-_38273823 1.726 YRDC
yrdC domain containing (E. coli)

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 111 entries
enrichment   p-value GO term description
3.17 3.47e-02 GO:0007030 Golgi organization
2.85 1.64e-02 GO:0006903 vesicle targeting
2.56 2.83e-02 GO:0006888 ER to Golgi vesicle-mediated transport
2.38 1.38e-04 GO:0006353 transcription termination, DNA-dependent
2.34 2.55e-09 GO:0048193 Golgi vesicle transport
2.28 1.20e-03 GO:0007173 epidermal growth factor receptor signaling pathway
2.24 6.13e-07 GO:0042254 ribosome biogenesis
2.20 1.46e-02 GO:0072594 establishment of protein localization to organelle
2.19 8.18e-11 GO:0022613 ribonucleoprotein complex biogenesis
2.19 4.03e-03 GO:0006354 transcription elongation, DNA-dependent
2.13 4.70e-02 GO:0051436 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
2.12 3.34e-10 GO:0071843 cellular component biogenesis at cellular level
2.11 3.37e-03 GO:0006364 rRNA processing
2.09 1.15e-02 GO:0051351 positive regulation of ligase activity
2.09 2.78e-02 GO:0031123 RNA 3'-end processing
2.07 6.92e-09 GO:0000375 RNA splicing, via transesterification reactions
2.07 2.61e-02 GO:0051443 positive regulation of ubiquitin-protein ligase activity
2.05 3.24e-08 GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
2.05 3.24e-08 GO:0000398 nuclear mRNA splicing, via spliceosome
2.05 6.28e-03 GO:0016072 rRNA metabolic process

Gene overrepresentation in compartment category:

Showing 1 to 20 of 39 entries
enrichment   p-value GO term description
3.40 4.67e-02 GO:0030663 COPI coated vesicle membrane
3.31 5.00e-04 GO:0005689 U12-type spliceosomal complex
3.23 3.70e-04 GO:0044452 nucleolar part
2.92 5.01e-06 GO:0015030 Cajal body
2.38 6.96e-11 GO:0005681 spliceosomal complex
2.23 1.54e-03 GO:0030117 membrane coat
2.23 1.54e-03 GO:0048475 coated membrane
2.12 4.10e-02 GO:0016605 PML body
2.11 1.91e-03 GO:0071013 catalytic step 2 spliceosome
1.98 3.18e-09 GO:0016604 nuclear body
1.79 1.14e-14 GO:0030529 ribonucleoprotein complex
1.79 2.36e-14 GO:0005730 nucleolus
1.58 4.04e-11 GO:0044451 nucleoplasm part
1.53 5.16e-27 GO:0031981 nuclear lumen
1.51 1.22e-29 GO:0044428 nuclear part
1.49 1.14e-15 GO:0005654 nucleoplasm
1.46 1.18e-25 GO:0070013 intracellular organelle lumen
1.45 1.60e-24 GO:0043233 organelle lumen
1.44 7.51e-25 GO:0031974 membrane-enclosed lumen
1.31 2.95e-38 GO:0005634 nucleus

Gene overrepresentation in function category:

Showing 1 to 17 of 17 entries
enrichment   p-value GO term description
2.82 1.78e-02 GO:0008173 RNA methyltransferase activity
2.00 1.76e-02 GO:0008135 translation factor activity, nucleic acid binding
1.82 3.79e-04 GO:0008168 methyltransferase activity
1.76 1.27e-03 GO:0016741 transferase activity, transferring one-carbon groups
1.59 1.49e-13 GO:0003723 RNA binding
1.38 3.98e-02 GO:0016874 ligase activity
1.29 1.28e-15 GO:0003676 nucleic acid binding
1.24 2.07e-05 GO:0008270 zinc ion binding
1.21 1.62e-04 GO:0000166 nucleotide binding
1.20 8.46e-03 GO:0035639 purine ribonucleoside triphosphate binding
1.19 2.56e-03 GO:0003677 DNA binding
1.19 1.81e-02 GO:0017076 purine nucleotide binding
1.19 2.18e-02 GO:0032553 ribonucleotide binding
1.19 2.18e-02 GO:0032555 purine ribonucleotide binding
1.18 3.78e-20 GO:0005515 protein binding
1.17 1.82e-02 GO:0046914 transition metal ion binding
1.10 5.47e-18 GO:0005488 binding