Motif ID: EOMES.p2

Z-value: 0.897


Transcription factors associated with EOMES.p2:

Gene SymbolEntrez IDGene Name
EOMES 8320 eomesodermin

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.p-valuePlot
EOMESchr3_-_27763784-0.358.9e-02Click!


Activity profile for motif EOMES.p2.

activity profile for motif EOMES.p2


Sorted Z-values histogram for motif EOMES.p2

Sorted Z-values for motif EOMES.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of EOMES.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr2_+_228678556 5.893 NM_001130046
NM_004591
 CCL20

chemokine (C-C motif) ligand 20

chr1_-_205290756 4.631 NM_030952
 NUAK2
NUAK family, SNF1-like kinase, 2
chr5_+_113698304 4.546 KCNN2
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2
chr5_+_113698015 3.458 NM_021614
 KCNN2
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2
chr17_+_25958257 3.301 LGALS9
lectin, galactoside-binding, soluble, 9
chr17_+_25958245 3.269 LGALS9
lectin, galactoside-binding, soluble, 9
chr20_-_62199106 3.234 NM_033405
 PRIC285
peroxisomal proliferator-activated receptor A interacting complex 285
chr19_+_10381763 3.215 ICAM1
intercellular adhesion molecule 1
chr17_-_20370819 3.214 NM_001042685
 LGALS9B
lectin, galactoside-binding, soluble, 9B
chr12_+_124773709 3.151 NM_181709
 FAM101A
family with sequence similarity 101, member A
chr1_+_212782103 2.690 ATF3
activating transcription factor 3
chr4_-_76957139 2.527 NM_005409
 CXCL11
chemokine (C-X-C motif) ligand 11
chr14_+_55034633 2.454 SAMD4A
sterile alpha motif domain containing 4A
chr17_+_25958217 2.386 LGALS9
lectin, galactoside-binding, soluble, 9
chr17_+_25958192 2.292 LGALS9
lectin, galactoside-binding, soluble, 9
chr17_+_25958151 2.273 NM_002308
NM_009587
 LGALS9

lectin, galactoside-binding, soluble, 9

chr5_+_35856990 2.254 NM_002185
 IL7R
interleukin 7 receptor
chr1_+_212781969 2.199 NM_001040619
NM_001206484
NM_001206488
NM_001674
 ATF3



activating transcription factor 3



chr19_-_17958773 2.122 JAK3
Janus kinase 3
chr5_+_125800786 2.114 NM_001146322
 GRAMD3
GRAM domain containing 3

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 28 entries
enrichment   p-value GO term description
2.22 1.05e-03 GO:0044057 regulation of system process
2.08 1.41e-02 GO:0071495 cellular response to endogenous stimulus
2.07 3.30e-02 GO:0032870 cellular response to hormone stimulus
2.01 6.27e-04 GO:0019226 transmission of nerve impulse
2.01 6.27e-04 GO:0035637 multicellular organismal signaling
1.99 4.46e-03 GO:0007268 synaptic transmission
1.94 5.31e-06 GO:0007267 cell-cell signaling
1.93 1.35e-08 GO:0007154 cell communication
1.75 1.37e-02 GO:0071310 cellular response to organic substance
1.63 1.16e-02 GO:0006811 ion transport
1.63 1.79e-02 GO:0040011 locomotion
1.57 4.90e-02 GO:0070887 cellular response to chemical stimulus
1.43 8.79e-04 GO:0065008 regulation of biological quality
1.43 2.58e-02 GO:0023051 regulation of signaling
1.42 1.35e-08 GO:0023052 signaling
1.38 2.00e-02 GO:0030154 cell differentiation
1.37 1.34e-05 GO:0007165 signal transduction
1.32 1.93e-05 GO:0051716 cellular response to stimulus
1.30 1.59e-02 GO:0048856 anatomical structure development
1.30 4.60e-02 GO:0048731 system development

Gene overrepresentation in compartment category:

Showing 1 to 12 of 12 entries
enrichment   p-value GO term description
2.51 1.51e-03 GO:0030424 axon
2.47 1.31e-02 GO:0045211 postsynaptic membrane
2.19 3.88e-02 GO:0030425 dendrite
1.96 2.66e-02 GO:0044456 synapse part
1.95 2.13e-03 GO:0043005 neuron projection
1.85 1.36e-02 GO:0045202 synapse
1.58 1.11e-04 GO:0005887 integral to plasma membrane
1.57 1.72e-04 GO:0031226 intrinsic to plasma membrane
1.47 2.85e-06 GO:0044459 plasma membrane part
1.41 4.87e-04 GO:0005576 extracellular region
1.24 2.99e-03 GO:0071944 cell periphery
1.24 4.17e-03 GO:0005886 plasma membrane

Gene overrepresentation in function category:

Showing 1 to 13 of 13 entries
enrichment   p-value GO term description
2.07 1.98e-04 GO:0015267 channel activity
2.06 2.14e-04 GO:0022803 passive transmembrane transporter activity
2.05 4.09e-04 GO:0022838 substrate-specific channel activity
2.03 1.02e-02 GO:0022836 gated channel activity
1.96 2.99e-03 GO:0005216 ion channel activity
1.77 5.86e-03 GO:0008324 cation transmembrane transporter activity
1.74 5.46e-05 GO:0022891 substrate-specific transmembrane transporter activity
1.73 6.79e-04 GO:0015075 ion transmembrane transporter activity
1.67 2.76e-04 GO:0022857 transmembrane transporter activity
1.65 1.98e-04 GO:0005102 receptor binding
1.61 8.19e-04 GO:0022892 substrate-specific transporter activity
1.49 8.07e-03 GO:0005215 transporter activity
1.19 6.38e-05 GO:0005515 protein binding