Motif ID: EP300.p2

Z-value: 0.735


Transcription factors associated with EP300.p2:

Gene SymbolEntrez IDGene Name
EP300 2033 E1A binding protein p300

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.p-valuePlot
EP300chr22_+_41488607-0.174.0e-01Click!


Activity profile for motif EP300.p2.

activity profile for motif EP300.p2


Sorted Z-values histogram for motif EP300.p2

Sorted Z-values for motif EP300.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of EP300.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr1_-_95007139 1.489 NM_001178096
NM_001993
 F3

coagulation factor III (thromboplastin, tissue factor)

chr5_-_131826426 0.814 NM_002198
 IRF1
interferon regulatory factor 1
chr9_-_123688352 0.725 TRAF1
TNF receptor-associated factor 1
chr16_+_77224865 0.582 MON1B
MON1 homolog B (yeast)
chr1_-_184943673 0.544 NM_052966
 FAM129A
family with sequence similarity 129, member A
chr11_+_102188180 0.534 NM_001165
NM_182962
 BIRC3

baculoviral IAP repeat containing 3

chr21_+_46293925 0.444


chr8_+_106331146 0.433 NM_012082
 ZFPM2
zinc finger protein, multitype 2
chr16_+_77224827 0.424 NM_014940
 MON1B
MON1 homolog B (yeast)
chr12_-_26277807 0.412 NM_030762
 BHLHE41
basic helix-loop-helix family, member e41
chr16_+_77225107 0.407 MON1B
MON1 homolog B (yeast)
chr3_-_79817058 0.375 NM_002941
 ROBO1
roundabout, axon guidance receptor, homolog 1 (Drosophila)
chr19_-_56632644 0.354 NM_001002836
 ZNF787
zinc finger protein 787
chr5_+_56111379 0.337 MAP3K1
mitogen-activated protein kinase kinase kinase 1
chr17_-_4851688 0.334 PFN1
profilin 1
chr2_-_100721792 0.326 NM_001025108
 AFF3
AF4/FMR2 family, member 3
chr4_-_38666429 0.321 FLJ13197
uncharacterized FLJ13197
chrX_+_140982451 0.316 NM_177456
 MAGEC3
melanoma antigen family C, 3
chr3_+_10206562 0.316 NM_001570
 IRAK2
interleukin-1 receptor-associated kinase 2
chr11_-_57194556 0.313 SLC43A3
solute carrier family 43, member 3

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 34 entries
enrichment   p-value GO term description
1.70 2.57e-02 GO:0030168 platelet activation
1.54 1.26e-04 GO:0042060 wound healing
1.54 2.20e-04 GO:0050878 regulation of body fluid levels
1.50 8.59e-03 GO:0007599 hemostasis
1.50 1.05e-02 GO:0007596 blood coagulation
1.50 1.05e-02 GO:0050817 coagulation
1.43 2.74e-02 GO:0010629 negative regulation of gene expression
1.36 1.19e-02 GO:0009611 response to wounding
1.35 8.95e-03 GO:0042127 regulation of cell proliferation
1.33 2.71e-02 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.31 8.12e-04 GO:0007399 nervous system development
1.29 6.86e-07 GO:0048522 positive regulation of cellular process
1.28 1.16e-02 GO:0009966 regulation of signal transduction
1.27 1.12e-06 GO:0048518 positive regulation of biological process
1.27 4.77e-03 GO:0023051 regulation of signaling
1.26 5.34e-05 GO:0048519 negative regulation of biological process
1.26 2.67e-04 GO:0048523 negative regulation of cellular process
1.23 6.19e-04 GO:0071842 cellular component organization at cellular level
1.22 4.60e-04 GO:0071841 cellular component organization or biogenesis at cellular level
1.22 3.08e-02 GO:0030154 cell differentiation

Gene overrepresentation in compartment category:

Showing 1 to 20 of 24 entries
enrichment   p-value GO term description
1.36 4.96e-02 GO:0030054 cell junction
1.35 2.92e-02 GO:0015630 microtubule cytoskeleton
1.30 1.73e-02 GO:0005794 Golgi apparatus
1.26 3.21e-05 GO:0005829 cytosol
1.22 1.05e-02 GO:0031981 nuclear lumen
1.19 6.09e-04 GO:0043234 protein complex
1.19 2.14e-02 GO:0044459 plasma membrane part
1.19 2.20e-02 GO:0043233 organelle lumen
1.19 2.35e-02 GO:0070013 intracellular organelle lumen
1.18 2.45e-02 GO:0031974 membrane-enclosed lumen
1.18 4.33e-02 GO:0044428 nuclear part
1.14 6.05e-05 GO:0005634 nucleus
1.13 1.64e-09 GO:0005737 cytoplasm
1.12 3.03e-04 GO:0044444 cytoplasmic part
1.11 1.27e-02 GO:0044422 organelle part
1.11 1.48e-02 GO:0044446 intracellular organelle part
1.08 1.58e-08 GO:0005622 intracellular
1.08 2.42e-08 GO:0044424 intracellular part
1.08 3.21e-04 GO:0043226 organelle
1.08 4.21e-04 GO:0043229 intracellular organelle

Gene overrepresentation in function category:

Showing 1 to 2 of 2 entries
enrichment   p-value GO term description
1.22 4.08e-22 GO:0005515 protein binding
1.07 6.84e-07 GO:0005488 binding