Motif ID: ESRRA.p2

Z-value: 0.903


Transcription factors associated with ESRRA.p2:

Gene SymbolEntrez IDGene Name
ESRRA 2101 estrogen-related receptor alpha

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.p-valuePlot
ESRRAchr11_+_640730400.125.7e-01Click!


Activity profile for motif ESRRA.p2.

activity profile for motif ESRRA.p2


Sorted Z-values histogram for motif ESRRA.p2

Sorted Z-values for motif ESRRA.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ESRRA.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr16_+_57050985 1.256 NM_032206
 NLRC5
NLR family, CARD domain containing 5
chr20_+_39969420 1.224 NM_022896
 LPIN3
lipin 3
chr12_+_78225068 1.037 NM_014903
 NAV3
neuron navigator 3
chr6_+_43149925 0.996 CUL9
cullin 9
chr21_+_27011766 0.890 JAM2
junctional adhesion molecule 2
chr19_+_35629727 0.841 NM_021902
 FXYD1
FXYD domain containing ion transport regulator 1
chr11_-_64528186 0.803 NM_001164716
NM_005609
 PYGM

phosphorylase, glycogen, muscle

chr12_-_120554557 0.793 RAB35
RAB35, member RAS oncogene family
chr10_+_81107242 0.789 PPIF
peptidylprolyl isomerase F
chr1_-_144994839 0.710 PDE4DIP
phosphodiesterase 4D interacting protein
chr17_-_4167028 0.652 NM_016376
NM_020740
 ANKFY1

ankyrin repeat and FYVE domain containing 1

chr1_-_8003224 0.652 NM_001561
 TNFRSF9
tumor necrosis factor receptor superfamily, member 9
chr1_+_205236591 0.600 TMCC2
transmembrane and coiled-coil domain family 2
chr10_+_81107259 0.596 PPIF
peptidylprolyl isomerase F
chr22_+_32149936 0.595 NM_001242897
 DEPDC5
DEP domain containing 5
chr4_-_76957139 0.593 NM_005409
 CXCL11
chemokine (C-X-C motif) ligand 11
chr19_-_1513187 0.589 NM_213604
 ADAMTSL5
ADAMTS-like 5
chr1_-_31712733 0.586 NM_024522
 NKAIN1
Na+/K+ transporting ATPase interacting 1
chr1_+_209848659 0.581 NM_015714
 G0S2
G0/G1switch 2
chr19_-_1512997 0.579 ADAMTSL5
ADAMTS-like 5

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 11 of 11 entries
enrichment   p-value GO term description
7.27 4.47e-02 GO:0072384 organelle transport along microtubule
5.35 1.90e-02 GO:0009060 aerobic respiration
5.35 1.90e-02 GO:0070585 protein localization in mitochondrion
3.90 2.31e-03 GO:0006839 mitochondrial transport
3.48 1.61e-04 GO:0045333 cellular respiration
3.46 7.21e-03 GO:0022904 respiratory electron transport chain
2.49 9.36e-04 GO:0015980 energy derivation by oxidation of organic compounds
2.28 2.42e-04 GO:0006091 generation of precursor metabolites and energy
1.44 1.56e-05 GO:0006810 transport
1.42 3.41e-05 GO:0051234 establishment of localization
1.37 1.43e-04 GO:0051179 localization

Gene overrepresentation in compartment category:

Showing 1 to 17 of 17 entries
enrichment   p-value GO term description
9.64 4.39e-03 GO:0005744 mitochondrial inner membrane presequence translocase complex
4.68 3.16e-02 GO:0042645 mitochondrial nucleoid
4.54 4.04e-02 GO:0009295 nucleoid
3.98 2.03e-07 GO:0044455 mitochondrial membrane part
3.48 2.69e-02 GO:0070469 respiratory chain
2.79 6.56e-08 GO:0005743 mitochondrial inner membrane
2.66 1.33e-07 GO:0019866 organelle inner membrane
2.52 1.47e-08 GO:0031966 mitochondrial membrane
2.49 1.12e-08 GO:0005740 mitochondrial envelope
2.28 8.07e-10 GO:0044429 mitochondrial part
2.19 1.36e-02 GO:0005759 mitochondrial matrix
2.01 1.84e-06 GO:0031967 organelle envelope
2.00 1.80e-06 GO:0031975 envelope
1.81 1.38e-08 GO:0005739 mitochondrion
1.40 4.89e-03 GO:0005829 cytosol
1.23 2.39e-04 GO:0044444 cytoplasmic part
1.18 8.98e-05 GO:0005737 cytoplasm

Gene overrepresentation in function category:

Showing 1 to 2 of 2 entries
enrichment   p-value GO term description
14.13 2.70e-02 GO:0008048 calcium sensitive guanylate cyclase activator activity
2.33 4.27e-02 GO:0005529 sugar binding