Motif ID: EVI1.p2

Z-value: 1.557


Transcription factors associated with EVI1.p2:

Gene SymbolEntrez IDGene Name
EVI1 2122 ecotropic viral integration site 1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.p-valuePlot
MECOMchr3_-_168864066-0.471.9e-02Click!


Activity profile for motif EVI1.p2.

activity profile for motif EVI1.p2


Sorted Z-values histogram for motif EVI1.p2

Sorted Z-values for motif EVI1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of EVI1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr21_+_43710190 7.433 ABCG1
ATP-binding cassette, sub-family G (WHITE), member 1
chr2_+_102979096 6.338 NM_003855
 IL18R1
interleukin 18 receptor 1
chr4_-_76944585 4.738 NM_001565
 CXCL10
chemokine (C-X-C motif) ligand 10
chr15_+_67418053 4.451 NM_001145102
 SMAD3
SMAD family member 3
chr8_+_17396285 4.261 NM_001164771
NM_003046
 SLC7A2

solute carrier family 7 (cationic amino acid transporter, y+ system), member 2

chr6_-_154831704 4.101 NM_173515
 CNKSR3
CNKSR family member 3
chr6_-_154831788 3.999 CNKSR3
CNKSR family member 3
chr5_+_125695787 3.884 NM_001146319
 GRAMD3
GRAM domain containing 3
chr6_+_126240369 3.867 NM_001199622
 NCOA7
nuclear receptor coactivator 7
chr6_-_154831652 3.737 CNKSR3
CNKSR family member 3
chr14_-_76447445 3.700 TGFB3
transforming growth factor, beta 3
chr8_-_6420454 3.471 NM_001118887
NM_001118888
NM_001147
 ANGPT2


angiopoietin 2


chr1_+_212738675 3.255 NM_001030287
 ATF3
activating transcription factor 3
chr15_-_55562483 3.193 NM_183234
NM_004580
 RAB27A

RAB27A, member RAS oncogene family

chr8_+_90770201 3.140 RIPK2
receptor-interacting serine-threonine kinase 2
chr12_-_9913415 3.100 NM_001781
 CD69
CD69 molecule
chr13_+_97928196 2.868 MBNL2
muscleblind-like 2 (Drosophila)
chr1_+_101185195 2.757 NM_001078
NM_001199834
NM_080682
 VCAM1


vascular cell adhesion molecule 1


chr18_+_61554938 2.700 NM_001143818
NM_002575
 SERPINB2

serpin peptidase inhibitor, clade B (ovalbumin), member 2

chr8_-_101315457 2.666 NM_015435
 RNF19A
ring finger protein 19A

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 15 of 15 entries
enrichment   p-value GO term description
8.12 1.85e-02 GO:0046640 regulation of alpha-beta T cell proliferation
2.35 9.17e-03 GO:0002694 regulation of leukocyte activation
2.26 2.13e-02 GO:0050865 regulation of cell activation
2.01 3.28e-03 GO:0050776 regulation of immune response
1.86 3.59e-02 GO:0009628 response to abiotic stimulus
1.78 4.90e-03 GO:0002682 regulation of immune system process
1.72 1.15e-03 GO:0009611 response to wounding
1.44 8.84e-03 GO:0007166 cell surface receptor linked signaling pathway
1.35 1.44e-04 GO:0007165 signal transduction
1.32 2.72e-04 GO:0023052 signaling
1.26 9.99e-03 GO:0051716 cellular response to stimulus
1.20 3.25e-02 GO:0032501 multicellular organismal process
1.19 1.82e-02 GO:0050896 response to stimulus
1.16 2.83e-03 GO:0065007 biological regulation
1.16 1.68e-02 GO:0050789 regulation of biological process

Gene overrepresentation in compartment category:

Showing 1 to 8 of 8 entries
enrichment   p-value GO term description
1.64 4.95e-03 GO:0005615 extracellular space
1.54 5.41e-03 GO:0044421 extracellular region part
1.52 1.25e-06 GO:0005576 extracellular region
1.41 2.28e-04 GO:0044459 plasma membrane part
1.30 1.76e-05 GO:0071944 cell periphery
1.29 4.24e-05 GO:0005886 plasma membrane
1.15 4.53e-02 GO:0044425 membrane part
1.13 1.85e-02 GO:0016020 membrane

Gene overrepresentation in function category:

Showing 1 to 4 of 4 entries
enrichment   p-value GO term description
12.99 3.81e-02 GO:0000099 sulfur amino acid transmembrane transporter activity
12.99 3.81e-02 GO:0015184 L-cystine transmembrane transporter activity
2.43 3.71e-02 GO:0030414 peptidase inhibitor activity
2.15 5.13e-04 GO:0022804 active transmembrane transporter activity