Motif ID: FEV.p2

Z-value: 1.395


Transcription factors associated with FEV.p2:

Gene SymbolEntrez IDGene Name
FEV 54738 FEV (ETS oncogene family)

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.p-valuePlot
FEVchr2_-_219850273-0.213.2e-01Click!


Activity profile for motif FEV.p2.

activity profile for motif FEV.p2


Sorted Z-values histogram for motif FEV.p2

Sorted Z-values for motif FEV.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of FEV.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr1_-_160313056 4.805 COPA
coatomer protein complex, subunit alpha
chr1_-_160312959 3.985


chr21_+_26934440 3.059 MIR155HG
MIR155 host gene (non-protein coding)
chr5_+_131409484 2.936 NM_000758
 CSF2
colony stimulating factor 2 (granulocyte-macrophage)
chr4_+_103422553 2.910 NFKB1
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
chr6_-_31550065 2.840 NM_002341
NM_009588
 LTB

lymphotoxin beta (TNF superfamily, member 3)

chr11_-_46722160 2.810 ARHGAP1
Rho GTPase activating protein 1
chr11_-_46722139 2.757 ARHGAP1
Rho GTPase activating protein 1
chr21_-_35899046 2.674 NM_203418
 RCAN1
regulator of calcineurin 1
chr6_-_11382501 2.405 NM_001142393
 NEDD9
neural precursor cell expressed, developmentally down-regulated 9
chr4_+_103422822 2.364 NFKB1
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
chr11_+_102188180 2.317 NM_001165
NM_182962
 BIRC3

baculoviral IAP repeat containing 3

chr6_+_126240369 2.245 NM_001199622
 NCOA7
nuclear receptor coactivator 7
chr4_+_103422730 2.148 NFKB1
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
chr13_+_111855406 2.122 ARHGEF7
Rho guanine nucleotide exchange factor (GEF) 7
chr4_+_103422479 2.114 NM_001165412
NM_003998
 NFKB1

nuclear factor of kappa light polypeptide gene enhancer in B-cells 1

chr1_-_160313029 2.066 COPA
coatomer protein complex, subunit alpha
chr17_+_26662547 2.003 NM_021137
 TNFAIP1
tumor necrosis factor, alpha-induced protein 1 (endothelial)
chr7_+_150065330 1.963 REPIN1
replication initiator 1
chr19_+_10381763 1.915 ICAM1
intercellular adhesion molecule 1

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 74 entries
enrichment   p-value GO term description
2.33 3.65e-02 GO:0006944 cellular membrane fusion
2.09 2.16e-03 GO:0050851 antigen receptor-mediated signaling pathway
2.09 2.85e-02 GO:0050852 T cell receptor signaling pathway
1.99 4.69e-03 GO:0002768 immune response-regulating cell surface receptor signaling pathway
1.98 1.04e-02 GO:0002429 immune response-activating cell surface receptor signaling pathway
1.92 9.58e-03 GO:0042110 T cell activation
1.84 3.00e-03 GO:0002697 regulation of immune effector process
1.84 2.31e-02 GO:0002521 leukocyte differentiation
1.82 2.24e-04 GO:0046649 lymphocyte activation
1.80 1.69e-05 GO:0045321 leukocyte activation
1.80 3.06e-02 GO:0048193 Golgi vesicle transport
1.71 1.62e-03 GO:0048011 nerve growth factor receptor signaling pathway
1.71 1.58e-02 GO:0002764 immune response-regulating signaling pathway
1.69 3.12e-02 GO:0002757 immune response-activating signal transduction
1.64 6.21e-08 GO:0001775 cell activation
1.60 4.11e-02 GO:0030168 platelet activation
1.57 3.70e-05 GO:0050776 regulation of immune response
1.55 1.48e-05 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
1.55 7.27e-04 GO:0007264 small GTPase mediated signal transduction
1.54 3.12e-02 GO:0050778 positive regulation of immune response

Gene overrepresentation in compartment category:

Showing 1 to 20 of 33 entries
enrichment   p-value GO term description
1.59 4.73e-02 GO:0031252 cell leading edge
1.45 1.63e-03 GO:0005768 endosome
1.37 2.52e-04 GO:0031410 cytoplasmic vesicle
1.36 2.41e-04 GO:0031982 vesicle
1.36 5.19e-04 GO:0031988 membrane-bounded vesicle
1.36 7.41e-04 GO:0016023 cytoplasmic membrane-bounded vesicle
1.33 2.74e-03 GO:0044432 endoplasmic reticulum part
1.31 4.11e-10 GO:0005829 cytosol
1.25 1.86e-05 GO:0031981 nuclear lumen
1.25 2.30e-03 GO:0005654 nucleoplasm
1.25 4.21e-02 GO:0005794 Golgi apparatus
1.23 1.62e-05 GO:0044428 nuclear part
1.22 1.17e-05 GO:0031974 membrane-enclosed lumen
1.22 2.13e-05 GO:0043233 organelle lumen
1.21 1.06e-04 GO:0070013 intracellular organelle lumen
1.21 6.84e-03 GO:0012505 endomembrane system
1.17 6.81e-12 GO:0044444 cytoplasmic part
1.17 5.93e-04 GO:0043234 protein complex
1.15 2.39e-17 GO:0005737 cytoplasm
1.14 3.13e-07 GO:0044422 organelle part

Gene overrepresentation in function category:

Showing 1 to 4 of 4 entries
enrichment   p-value GO term description
2.88 6.41e-03 GO:0004693 cyclin-dependent protein kinase activity
1.80 2.30e-02 GO:0030674 protein binding, bridging
1.19 3.39e-22 GO:0005515 protein binding
1.07 4.90e-07 GO:0005488 binding