Motif ID: FEV.p2

Z-value: 1.395


Transcription factors associated with FEV.p2:

Gene SymbolEntrez IDGene Name
FEV 54738 FEV (ETS oncogene family)

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.p-valuePlot
FEVchr2_-_219850273-0.213.2e-01Click!


Activity profile for motif FEV.p2.

activity profile for motif FEV.p2


Sorted Z-values histogram for motif FEV.p2

Sorted Z-values for motif FEV.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of FEV.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_-_160313056 4.805 COPA
coatomer protein complex, subunit alpha
chr1_-_160312959 3.985


chr21_+_26934440 3.059 MIR155HG
MIR155 host gene (non-protein coding)
chr5_+_131409484 2.936 NM_000758
CSF2
colony stimulating factor 2 (granulocyte-macrophage)
chr4_+_103422553 2.910 NFKB1
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
chr6_-_31550065 2.840 NM_002341
NM_009588
LTB

lymphotoxin beta (TNF superfamily, member 3)

chr11_-_46722160 2.810 ARHGAP1
Rho GTPase activating protein 1
chr11_-_46722139 2.757 ARHGAP1
Rho GTPase activating protein 1
chr21_-_35899046 2.674 NM_203418
RCAN1
regulator of calcineurin 1
chr6_-_11382501 2.405 NM_001142393
NEDD9
neural precursor cell expressed, developmentally down-regulated 9
chr4_+_103422822 2.364 NFKB1
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
chr11_+_102188180 2.317 NM_001165
NM_182962
BIRC3

baculoviral IAP repeat containing 3

chr6_+_126240369 2.245 NM_001199622
NCOA7
nuclear receptor coactivator 7
chr4_+_103422730 2.148 NFKB1
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
chr13_+_111855406 2.122 ARHGEF7
Rho guanine nucleotide exchange factor (GEF) 7
chr4_+_103422479 2.114 NM_001165412
NM_003998
NFKB1

nuclear factor of kappa light polypeptide gene enhancer in B-cells 1

chr1_-_160313029 2.066 COPA
coatomer protein complex, subunit alpha
chr17_+_26662547 2.003 NM_021137
TNFAIP1
tumor necrosis factor, alpha-induced protein 1 (endothelial)
chr7_+_150065330 1.963 REPIN1
replication initiator 1
chr19_+_10381763 1.915 ICAM1
intercellular adhesion molecule 1
chr2_+_228678556 1.913 NM_001130046
NM_004591
CCL20

chemokine (C-C motif) ligand 20

chr21_-_38639593 1.862 DSCR3
Down syndrome critical region gene 3
chr2_+_161993465 1.830 NM_004180
NM_133484
TANK

TRAF family member-associated NFKB activator

chr12_+_100660846 1.824 SCYL2
SCY1-like 2 (S. cerevisiae)
chr5_+_125758818 1.820 NM_001146320
NM_001146321
NM_023927
GRAMD3


GRAM domain containing 3


chr1_-_169703178 1.733 NM_000450
SELE
selectin E
chr5_+_125759076 1.731 GRAMD3
GRAM domain containing 3
chr1_+_212738675 1.667 NM_001030287
ATF3
activating transcription factor 3
chr4_-_74904329 1.664 NM_002090
CXCL3
chemokine (C-X-C motif) ligand 3
chr12_+_100661158 1.656 SCYL2
SCY1-like 2 (S. cerevisiae)
chr19_+_50879681 1.620 NM_007121
NR1H2
nuclear receptor subfamily 1, group H, member 2
chr9_-_123689172 1.618 NM_005658
TRAF1
TNF receptor-associated factor 1
chr4_+_74606222 1.608 NM_000584
IL8
interleukin 8
chr15_-_59665053 1.540 MYO1E
myosin IE
chr2_+_231578262 1.499 NM_001130849
NM_001130850
CAB39

calcium binding protein 39

chr3_+_113465901 1.414 ATP6V1A
ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A
chr15_-_74988325 1.355 EDC3
enhancer of mRNA decapping 3 homolog (S. cerevisiae)
chr1_-_150552077 1.347 MCL1
myeloid cell leukemia sequence 1 (BCL2-related)
chr6_-_11232900 1.341 NEDD9
neural precursor cell expressed, developmentally down-regulated 9
chr3_+_11267666 1.320 NM_001098211
HRH1
histamine receptor H1
chr9_+_116356199 1.313 NM_144489
RGS3
regulator of G-protein signaling 3
chr17_-_79829237 1.278 ARHGDIA
Rho GDP dissociation inhibitor (GDI) alpha
chr6_-_143266283 1.267 NM_006734
HIVEP2
human immunodeficiency virus type I enhancer binding protein 2
chr5_+_140749830 1.266 NM_018924
NM_032097
PCDHGB3

protocadherin gamma subfamily B, 3

chr16_+_29674564 1.246 SPN
sialophorin
chr1_+_101185195 1.237 NM_001078
NM_001199834
NM_080682
VCAM1


vascular cell adhesion molecule 1


chr19_+_10381516 1.204 NM_000201
ICAM1
intercellular adhesion molecule 1
chr17_-_79829272 1.199 NM_001185078
NM_004309
ARHGDIA

Rho GDP dissociation inhibitor (GDI) alpha

chr6_+_138188352 1.198 NM_006290
TNFAIP3
tumor necrosis factor, alpha-induced protein 3
chr1_-_160313353 1.196 NM_001098398
NM_004371
COPA

coatomer protein complex, subunit alpha

chr9_-_130616592 1.188 ENG
endoglin
chr8_+_86158004 1.185 CA13
carbonic anhydrase XIII
chr15_-_59665069 1.164 NM_004998
MYO1E
myosin IE
chr18_+_11851388 1.131 NM_020412
CHMP1B
charged multivesicular body protein 1B
chr14_+_69865095 1.126 NM_001252151
NM_001252152
SLC39A9

solute carrier family 39 (zinc transporter), member 9

chr1_-_27216585 1.120 GPN2
GPN-loop GTPase 2
chrX_-_45060081 1.118 NM_024689
NM_176819
CXorf36

chromosome X open reading frame 36

chr1_-_27216767 1.105 GPN2
GPN-loop GTPase 2
chr13_+_111806070 1.098 ARHGEF7
Rho guanine nucleotide exchange factor (GEF) 7
chr13_+_111806038 1.089 NM_003899
ARHGEF7
Rho guanine nucleotide exchange factor (GEF) 7
chr10_+_102107074 1.087 SCD
stearoyl-CoA desaturase (delta-9-desaturase)
chr11_-_46722115 1.081 NM_004308
ARHGAP1
Rho GTPase activating protein 1
chr3_-_71179736 1.080 FOXP1
forkhead box P1
chr22_-_19512859 1.076 NM_001130861
NM_003277
CLDN5

claudin 5

chr11_+_93862060 1.059 NM_015368
PANX1
pannexin 1
chr15_+_62359175 1.057 NM_207322
C2CD4A
C2 calcium-dependent domain containing 4A
chr13_+_46039024 1.045 NM_031431
COG3
component of oligomeric golgi complex 3
chr12_+_112856756 1.041 PTPN11
protein tyrosine phosphatase, non-receptor type 11
chr15_-_50411405 1.037 NM_024837
ATP8B4
ATPase, class I, type 8B, member 4
chr17_+_40985412 1.036 PSME3
proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)
chr6_-_43595079 1.028 GTPBP2
GTP binding protein 2
chr2_+_61108775 1.020 REL
v-rel reticuloendotheliosis viral oncogene homolog (avian)
chr12_+_109915461 1.014 UBE3B
ubiquitin protein ligase E3B
chr19_-_59070324 1.013 NM_003969
UBE2M
ubiquitin-conjugating enzyme E2M
chr12_+_45609832 1.010 ANO6
anoctamin 6
chr2_-_192711651 1.009 SDPR
serum deprivation response
chr5_-_121413967 0.995 LOX
lysyl oxidase
chr14_+_55034633 0.985 SAMD4A
sterile alpha motif domain containing 4A
chr14_-_51134862 0.981 SAV1
salvador homolog 1 (Drosophila)
chr14_+_69865380 0.979 NM_001252148
NM_001252150
NM_018375
SLC39A9


solute carrier family 39 (zinc transporter), member 9


chr11_+_93862143 0.972 PANX1
pannexin 1
chr12_-_9913415 0.972 NM_001781
CD69
CD69 molecule
chr14_+_55034329 0.972 NM_001161576
NM_015589
SAMD4A

sterile alpha motif domain containing 4A

chr11_-_76381787 0.969 NM_001128922
LRRC32
leucine rich repeat containing 32
chr12_+_45609867 0.969 NM_001142680
ANO6
anoctamin 6
chr8_+_86089618 0.965 NM_001083588
NM_001951
E2F5

E2F transcription factor 5, p130-binding

chr8_+_86089641 0.960


chr7_+_100770378 0.956 NM_000602
NM_001165413
SERPINE1

serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1

chr10_+_102107256 0.952


chr3_+_53195214 0.935 NM_006254
NM_212539
PRKCD

protein kinase C, delta

chr14_-_51135021 0.914 NM_021818
SAV1
salvador homolog 1 (Drosophila)
chr9_+_82187469 0.907 TLE4
transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chr17_-_63052707 0.902 GNA13
guanine nucleotide binding protein (G protein), alpha 13
chr11_+_130029699 0.898 ST14
suppression of tumorigenicity 14 (colon carcinoma)
chr21_+_27107522 0.892 GABPA
GA binding protein transcription factor, alpha subunit 60kDa
chr15_-_74988342 0.888 NM_001142443
NM_001142444
NM_025083
EDC3


enhancer of mRNA decapping 3 homolog (S. cerevisiae)


chr19_-_56632600 0.881 ZNF787
zinc finger protein 787
chr14_-_57735527 0.879 EXOC5
exocyst complex component 5
chr1_-_221910801 0.878 NM_144728
DUSP10
dual specificity phosphatase 10
chr10_+_102106958 0.875 SCD
stearoyl-CoA desaturase (delta-9-desaturase)
chr17_+_40985434 0.869 PSME3
proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)
chr1_-_41328002 0.864 NM_133467
CITED4
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4
chr1_+_114522029 0.864 NM_020190
OLFML3
olfactomedin-like 3
chr14_-_51135041 0.862 SAV1
salvador homolog 1 (Drosophila)
chr20_-_62339309 0.862 NM_001134758
NM_003224
ARFRP1

ADP-ribosylation factor related protein 1

chr2_-_28113954 0.861 LOC100302650
uncharacterized LOC100302650
chr11_-_59436366 0.852 PATL1
protein associated with topoisomerase II homolog 1 (yeast)
chr5_+_68530736 0.846 CDK7
cyclin-dependent kinase 7
chr5_+_68530713 0.845 CDK7
cyclin-dependent kinase 7
chr15_-_62457481 0.834 NM_001007595
C2CD4B
C2 calcium-dependent domain containing 4B
chr12_-_49259549 0.828 NM_014470
RND1
Rho family GTPase 1
chr8_+_42128821 0.823 IKBKB
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
chr16_+_31085722 0.820 NM_014699
ZNF646
zinc finger protein 646
chr14_-_100842637 0.819 WARS
tryptophanyl-tRNA synthetase
chr12_-_6798419 0.814 ZNF384
zinc finger protein 384
chr20_-_62339205 0.813 ARFRP1
ADP-ribosylation factor related protein 1
chr20_+_44746889 0.809 NM_001250
NM_152854
CD40

CD40 molecule, TNF receptor superfamily member 5

chr11_-_104034685 0.807 PDGFD
platelet derived growth factor D
chr2_+_162016926 0.800 NM_001199135
TANK
TRAF family member-associated NFKB activator
chr5_-_121412805 0.799 NM_001178102
LOX
lysyl oxidase
chr5_+_68530621 0.797 NM_001799
CDK7
cyclin-dependent kinase 7
chr5_+_140797270 0.797 PCDHGB7
protocadherin gamma subfamily B, 7
chr9_+_116356407 0.792 RGS3
regulator of G-protein signaling 3
chr5_+_140739589 0.788 NM_018923
NM_032096
PCDHGB2

protocadherin gamma subfamily B, 2

chr17_+_32582295 0.786 NM_002982
CCL2
chemokine (C-C motif) ligand 2
chr6_-_33168448 0.773 RXRB
retinoid X receptor, beta
chr2_-_27579277 0.773 GTF3C2
general transcription factor IIIC, polypeptide 2, beta 110kDa
chr11_-_3078596 0.773 NM_001014437
NM_001194997
NM_001751
NM_139273
CARS



cysteinyl-tRNA synthetase



chr8_-_82395401 0.764 NM_001442
FABP4
fatty acid binding protein 4, adipocyte
chr1_-_154946830 0.763 SHC1
SHC (Src homology 2 domain containing) transforming protein 1
chr4_+_8200918 0.762 NM_018986
SH3TC1
SH3 domain and tetratricopeptide repeats 1
chr20_+_44746948 0.761 CD40
CD40 molecule, TNF receptor superfamily member 5
chr13_+_97928414 0.760 MBNL2
muscleblind-like 2 (Drosophila)
chr14_+_63671101 0.749 NM_020663
RHOJ
ras homolog gene family, member J
chr6_-_167571315 0.746 NM_005299
GPR31
G protein-coupled receptor 31
chr3_-_195808980 0.746 TFRC
transferrin receptor (p90, CD71)
chr17_+_15848230 0.744 NM_000676
ADORA2B
adenosine A2b receptor
chr5_-_54281345 0.744 NM_001135604
NM_007036
ESM1

endothelial cell-specific molecule 1

chr1_+_110091218 0.743 GNAI3
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3
chr6_+_111580568 0.739 KIAA1919
KIAA1919
chr5_+_153418544 0.736 MFAP3
microfibrillar-associated protein 3
chr9_-_130616760 0.725 ENG
endoglin
chr11_-_59436488 0.720 NM_152716
PATL1
protein associated with topoisomerase II homolog 1 (yeast)
chr6_+_41040713 0.718 NFYA
nuclear transcription factor Y, alpha
chr2_+_103035148 0.714 NM_003853
IL18RAP
interleukin 18 receptor accessory protein
chr5_+_133984234 0.708 NM_001252231
NM_021982
SEC24A

SEC24 family, member A (S. cerevisiae)

chr2_+_28615771 0.706 NM_005253
FOSL2
FOS-like antigen 2
chr13_+_97928196 0.705 MBNL2
muscleblind-like 2 (Drosophila)
chr2_-_208031570 0.705 KLF7
Kruppel-like factor 7 (ubiquitous)
chr1_+_110091185 0.703 NM_006496
GNAI3
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3
chr2_-_27579626 0.703 GTF3C2
general transcription factor IIIC, polypeptide 2, beta 110kDa
chr17_+_40985444 0.701 PSME3
proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)
chr12_-_93835659 0.700 UBE2N
ubiquitin-conjugating enzyme E2N
chr1_-_27216784 0.699 NM_018066
GPN2
GPN-loop GTPase 2
chr6_-_169654047 0.699 NM_003247
THBS2
thrombospondin 2
chr16_-_31085503 0.699 NM_024706
ZNF668
zinc finger protein 668
chr14_+_70233803 0.698 SRSF5
serine/arginine-rich splicing factor 5
chr3_+_119013216 0.698 NM_020754
ARHGAP31
Rho GTPase activating protein 31
chr10_+_49892860 0.693 WDFY4
WDFY family member 4
chr17_+_40610897 0.693 ATP6V0A1
ATPase, H+ transporting, lysosomal V0 subunit a1
chr5_+_31799030 0.691 NM_178140
PDZD2
PDZ domain containing 2
chr5_-_121413906 0.689 LOX
lysyl oxidase
chr12_-_123214882 0.688 NM_032554
HCAR1
hydroxycarboxylic acid receptor 1
chrX_+_21857745 0.688 MBTPS2
membrane-bound transcription factor peptidase, site 2
chr19_+_4247049 0.685 NM_018074
CCDC94
coiled-coil domain containing 94
chr19_+_17420352 0.685 DDA1
DET1 and DDB1 associated 1
chr13_+_97874704 0.684 MBNL2
muscleblind-like 2 (Drosophila)
chr5_-_88178964 0.683 MEF2C
myocyte enhancer factor 2C
chr14_+_70233810 0.682 SRSF5
serine/arginine-rich splicing factor 5
chr14_+_73603140 0.680 NM_000021
NM_007318
PSEN1

presenilin 1

chr14_-_21852161 0.679 SUPT16H
suppressor of Ty 16 homolog (S. cerevisiae)
chr16_+_67063214 0.675 CBFB
core-binding factor, beta subunit
chr1_+_110091249 0.675 GNAI3
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3
chr1_-_150738255 0.671 CTSS
cathepsin S
chr1_-_214724565 0.669 PTPN14
protein tyrosine phosphatase, non-receptor type 14
chr11_-_71791734 0.669 NUMA1
nuclear mitotic apparatus protein 1
chr12_+_9142136 0.669 NM_005810
KLRG1
killer cell lectin-like receptor subfamily G, member 1
chr14_-_21852085 0.665 SUPT16H
suppressor of Ty 16 homolog (S. cerevisiae)
chr21_+_27107731 0.665 GABPA
GA binding protein transcription factor, alpha subunit 60kDa
chr17_-_79269061 0.663 SLC38A10
solute carrier family 38, member 10
chr4_-_74964996 0.661 NM_002089
CXCL2
chemokine (C-X-C motif) ligand 2
chr17_-_1303402 0.660 YWHAE
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide
chr1_-_41328019 0.656 CITED4
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4
chr1_-_154946859 0.654 NM_001130041
NM_001202859
NM_003029
SHC1


SHC (Src homology 2 domain containing) transforming protein 1


chr5_+_153418518 0.651 NM_001135037
NM_001242336
NM_005927
MFAP3


microfibrillar-associated protein 3


chr7_+_18548899 0.651 NM_001204147
NM_001204148
HDAC9

histone deacetylase 9

chr3_+_184032414 0.649 EIF4G1
eukaryotic translation initiation factor 4 gamma, 1
chr17_+_40985425 0.648 PSME3
proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)
chr17_+_40610940 0.647 ATP6V0A1
ATPase, H+ transporting, lysosomal V0 subunit a1
chr2_+_28616346 0.646 FOSL2
FOS-like antigen 2
chr5_+_38845962 0.645 NM_003999
OSMR
oncostatin M receptor
chr4_-_101439071 0.640 NM_001159694
NM_016242
EMCN

endomucin

chr12_-_9268522 0.640 NM_000014
A2M
alpha-2-macroglobulin
chr9_-_130616957 0.636 ENG
endoglin
chr12_-_9268513 0.631 A2M
alpha-2-macroglobulin
chr17_+_18218608 0.629 SMCR8
Smith-Magenis syndrome chromosome region, candidate 8
chr12_-_89918531 0.627 NM_003774
GALNT4
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 4 (GalNAc-T4)
chr11_+_128563955 0.621 FLI1
Friend leukemia virus integration 1
chr7_+_157129659 0.620 NM_005494
NM_058246
DNAJB6

TMEM135
DnaJ (Hsp40) homolog, subfamily B, member 6

transmembrane protein 135
chr11_-_104035023 0.616 NM_025208
NM_033135
PDGFD

platelet derived growth factor D


Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.11 1.26e-16 GO:0009987 cellular process
1.13 5.23e-10 GO:0065007 biological regulation
1.13 3.01e-09 GO:0050789 regulation of biological process
1.23 7.81e-09 GO:0007165 signal transduction
1.32 2.12e-08 GO:0048583 regulation of response to stimulus
1.64 6.21e-08 GO:0001775 cell activation
1.19 9.80e-08 GO:0051716 cellular response to stimulus
1.13 1.07e-07 GO:0050794 regulation of cellular process
1.20 1.57e-07 GO:0023052 signaling
1.18 2.05e-07 GO:0044260 cellular macromolecule metabolic process
1.16 7.38e-07 GO:0043170 macromolecule metabolic process
1.36 1.22e-06 GO:0002376 immune system process
1.22 6.81e-06 GO:0048518 positive regulation of biological process
1.55 1.48e-05 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
1.44 1.65e-05 GO:0006955 immune response
1.80 1.69e-05 GO:0045321 leukocyte activation
1.28 2.50e-05 GO:0009059 macromolecule biosynthetic process
1.57 3.70e-05 GO:0050776 regulation of immune response
1.40 4.20e-05 GO:0015031 protein transport
1.28 4.73e-05 GO:0034645 cellular macromolecule biosynthetic process
1.31 5.90e-05 GO:0035556 intracellular signal transduction
1.22 6.67e-05 GO:0006950 response to stress
1.27 8.58e-05 GO:0016070 RNA metabolic process
1.21 8.63e-05 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.44 9.44e-05 GO:0002682 regulation of immune system process
1.34 1.30e-04 GO:0008104 protein localization
1.38 1.36e-04 GO:0045184 establishment of protein localization
1.38 2.15e-04 GO:0006351 transcription, DNA-dependent
1.82 2.24e-04 GO:0046649 lymphocyte activation
1.25 2.31e-04 GO:0010467 gene expression
1.30 2.64e-04 GO:0033036 macromolecule localization
1.40 3.81e-04 GO:0016192 vesicle-mediated transport
1.39 4.73e-04 GO:0046907 intracellular transport
1.22 4.77e-04 GO:0090304 nucleic acid metabolic process
1.21 6.70e-04 GO:0048522 positive regulation of cellular process
1.55 7.27e-04 GO:0007264 small GTPase mediated signal transduction
1.11 7.29e-04 GO:0050896 response to stimulus
1.29 1.08e-03 GO:0051641 cellular localization
1.42 1.14e-03 GO:0007167 enzyme linked receptor protein signaling pathway
1.11 1.30e-03 GO:0044238 primary metabolic process
1.71 1.62e-03 GO:0048011 nerve growth factor receptor signaling pathway
1.20 1.84e-03 GO:0048519 negative regulation of biological process
1.23 2.07e-03 GO:0006464 protein modification process
2.09 2.16e-03 GO:0050851 antigen receptor-mediated signaling pathway
1.49 2.49e-03 GO:0002684 positive regulation of immune system process
1.32 2.81e-03 GO:0032774 RNA biosynthetic process
1.84 3.00e-03 GO:0002697 regulation of immune effector process
1.48 3.33e-03 GO:0016044 cellular membrane organization
1.48 4.43e-03 GO:0061024 membrane organization
1.99 4.69e-03 GO:0002768 immune response-regulating cell surface receptor signaling pathway
1.45 5.02e-03 GO:0007599 hemostasis
1.15 6.09e-03 GO:0071840 cellular component organization or biogenesis
1.21 8.02e-03 GO:0043412 macromolecule modification
1.20 8.52e-03 GO:0048523 negative regulation of cellular process
1.41 8.99e-03 GO:0050878 regulation of body fluid levels
1.92 9.58e-03 GO:0042110 T cell activation
1.44 9.58e-03 GO:0007596 blood coagulation
1.44 9.58e-03 GO:0050817 coagulation
1.98 1.04e-02 GO:0002429 immune response-activating cell surface receptor signaling pathway
1.71 1.58e-02 GO:0002764 immune response-regulating signaling pathway
1.10 1.59e-02 GO:0044237 cellular metabolic process
1.22 2.01e-02 GO:0023051 regulation of signaling
1.21 2.13e-02 GO:0007166 cell surface receptor linked signaling pathway
1.84 2.31e-02 GO:0002521 leukocyte differentiation
1.27 2.53e-02 GO:0051649 establishment of localization in cell
1.18 2.70e-02 GO:0042221 response to chemical stimulus
2.09 2.85e-02 GO:0050852 T cell receptor signaling pathway
1.30 3.02e-02 GO:0009611 response to wounding
1.80 3.06e-02 GO:0048193 Golgi vesicle transport
1.69 3.12e-02 GO:0002757 immune response-activating signal transduction
1.54 3.12e-02 GO:0050778 positive regulation of immune response
1.38 3.25e-02 GO:0042060 wound healing
2.33 3.65e-02 GO:0006944 cellular membrane fusion
1.60 4.11e-02 GO:0030168 platelet activation

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.15 2.39e-17 GO:0005737 cytoplasm
1.09 5.06e-12 GO:0044424 intracellular part
1.17 6.81e-12 GO:0044444 cytoplasmic part
1.08 7.16e-12 GO:0005622 intracellular
1.31 4.11e-10 GO:0005829 cytosol
1.14 3.13e-07 GO:0044422 organelle part
1.14 6.01e-07 GO:0044446 intracellular organelle part
1.09 3.56e-06 GO:0043227 membrane-bounded organelle
1.09 4.55e-06 GO:0043231 intracellular membrane-bounded organelle
1.22 1.17e-05 GO:0031974 membrane-enclosed lumen
1.23 1.62e-05 GO:0044428 nuclear part
1.25 1.86e-05 GO:0031981 nuclear lumen
1.03 2.06e-05 GO:0044464 cell part
1.22 2.13e-05 GO:0043233 organelle lumen
1.03 2.19e-05 GO:0005623 cell
1.08 2.42e-05 GO:0043229 intracellular organelle
1.08 2.61e-05 GO:0043226 organelle
1.21 1.06e-04 GO:0070013 intracellular organelle lumen
1.36 2.41e-04 GO:0031982 vesicle
1.37 2.52e-04 GO:0031410 cytoplasmic vesicle
1.36 5.19e-04 GO:0031988 membrane-bounded vesicle
1.17 5.93e-04 GO:0043234 protein complex
1.36 7.41e-04 GO:0016023 cytoplasmic membrane-bounded vesicle
1.45 1.63e-03 GO:0005768 endosome
1.14 1.65e-03 GO:0032991 macromolecular complex
1.25 2.30e-03 GO:0005654 nucleoplasm
1.33 2.74e-03 GO:0044432 endoplasmic reticulum part
1.21 6.84e-03 GO:0012505 endomembrane system
1.10 1.09e-02 GO:0005634 nucleus
1.25 4.21e-02 GO:0005794 Golgi apparatus
1.59 4.73e-02 GO:0031252 cell leading edge
1.14 4.96e-02 GO:0043228 non-membrane-bounded organelle
1.14 4.96e-02 GO:0043232 intracellular non-membrane-bounded organelle

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.19 3.39e-22 GO:0005515 protein binding
1.07 4.90e-07 GO:0005488 binding
2.88 6.41e-03 GO:0004693 cyclin-dependent protein kinase activity
1.80 2.30e-02 GO:0030674 protein binding, bridging