Motif ID: FOX{F1,F2,J1}.p2

Z-value: 0.798


Transcription factors associated with FOX{F1,F2,J1}.p2:

Gene SymbolEntrez IDGene Name
FOXF1 2294 forkhead box F1
FOXF2 2295 forkhead box F2
FOXJ1 2302 forkhead box J1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.p-valuePlot
FOXF1chr16_+_86544104-0.629.3e-04Click!
FOXJ1chr17_-_741373700.423.6e-02Click!
FOXF2chr6_+_1390068-0.252.3e-01Click!


Activity profile for motif FOX{F1,F2,J1}.p2.

activity profile for motif FOX{F1,F2,J1}.p2


Sorted Z-values histogram for motif FOX{F1,F2,J1}.p2

Sorted Z-values for motif FOX{F1,F2,J1}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of FOX{F1,F2,J1}.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr20_-_45976626 2.063 ZMYND8
zinc finger, MYND-type containing 8
chr8_-_93075190 1.755 NM_004349
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr6_+_136172802 1.691 NM_018945
PDE7B
phosphodiesterase 7B
chr2_-_165424993 1.672 GRB14
growth factor receptor-bound protein 14
chr16_-_86542463 1.606 LOC400550
uncharacterized LOC400550
chr8_-_28243941 1.502 NM_018660
ZNF395
zinc finger protein 395
chr8_-_22550708 1.466 NM_004430
EGR3
early growth response 3
chr3_+_143692166 1.345 NM_001134470
C3orf58
chromosome 3 open reading frame 58
chr8_-_93107442 1.281 NM_001198629
NM_001198630
NM_001198632
NM_175635
RUNX1T1



runt-related transcription factor 1; translocated to, 1 (cyclin D-related)



chr1_-_154127591 1.244 NM_001159484
NM_207308
NUP210L

nucleoporin 210kDa-like

chr3_-_168865521 1.194 NM_001164000
MECOM
MDS1 and EVI1 complex locus
chr11_-_27723061 1.180 NM_170733
BDNF
brain-derived neurotrophic factor
chr9_+_120466453 1.156 NM_138554
TLR4
toll-like receptor 4
chr9_+_79093256 1.101 NM_001097635
GCNT1
glucosaminyl (N-acetyl) transferase 1, core 2
chr9_-_86432546 1.096 NM_001135953
NM_025211
GKAP1

G kinase anchoring protein 1

chr7_+_129906702 1.082 NM_001869
CPA2
carboxypeptidase A2 (pancreatic)
chr9_+_120466607 1.059 TLR4
toll-like receptor 4
chr12_-_15038724 1.038 NM_000900
NM_001190839
MGP

matrix Gla protein

chr2_+_12856813 0.993 NM_021643
TRIB2
tribbles homolog 2 (Drosophila)
chr15_+_80390757 0.985 NM_001242919
ZFAND6
zinc finger, AN1-type domain 6
chr9_+_120466625 0.935 TLR4
toll-like receptor 4
chr12_-_80307690 0.925 NM_001143886
PPP1R12A
protein phosphatase 1, regulatory subunit 12A
chr6_-_76203256 0.920 NM_015687
FILIP1
filamin A interacting protein 1
chr3_+_156392369 0.917 TIPARP
TCDD-inducible poly(ADP-ribose) polymerase
chr9_-_3223007 0.914


chr19_+_18496966 0.907 NM_004864
GDF15
growth differentiation factor 15
chr22_-_17747520 0.905 CECR3
cat eye syndrome chromosome region, candidate 3 (non-protein coding)
chr8_-_93107643 0.889 RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr1_+_65730423 0.884 NM_014787
DNAJC6
DnaJ (Hsp40) homolog, subfamily C, member 6
chr12_-_10021932 0.883 CLEC2B
C-type lectin domain family 2, member B
chr8_-_93115453 0.880 NM_001198633
NM_175634
RUNX1T1

runt-related transcription factor 1; translocated to, 1 (cyclin D-related)

chr1_+_22351984 0.879 LINC00339
long intergenic non-protein coding RNA 339
chr4_-_186732047 0.868 NM_001145672
SORBS2
sorbin and SH3 domain containing 2
chr3_+_156392204 0.835 NM_015508
TIPARP
TCDD-inducible poly(ADP-ribose) polymerase
chr3_-_168864066 0.832 NM_001105077
NM_001163999
NM_005241
MECOM


MDS1 and EVI1 complex locus


chr13_+_41885340 0.819 NM_001110798
NM_018527
NM_024561
NAA16


N(alpha)-acetyltransferase 16, NatA auxiliary subunit


chr17_+_39382878 0.817 NM_031961
KRTAP9-2
keratin associated protein 9-2
chr7_+_12250818 0.808 NM_001134232
NM_018374
TMEM106B

transmembrane protein 106B

chr5_-_997408 0.798 NM_001242737
LOC100506688
uncharacterized LOC100506688
chr17_+_67410825 0.797 NM_002758
MAP2K6
mitogen-activated protein kinase kinase 6
chr2_+_33661392 0.757 NM_170672
RASGRP3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr4_-_186732208 0.726 NM_001145671
SORBS2
sorbin and SH3 domain containing 2
chr1_+_185703470 0.725 NM_031935
HMCN1
hemicentin 1
chr19_+_35417806 0.686 NM_001099437
NM_001099438
NM_194325
ZNF30


zinc finger protein 30


chr8_-_80993009 0.686 NM_001025252
TPD52
tumor protein D52
chr12_+_79258588 0.681 SYT1
synaptotagmin I
chr14_-_74551159 0.677 NM_005589
ALDH6A1
aldehyde dehydrogenase 6 family, member A1
chr15_-_70994608 0.672 NM_001008224
UACA
uveal autoantigen with coiled-coil domains and ankyrin repeats
chr1_+_84630575 0.663 NM_001242860
NM_001242861
PRKACB

protein kinase, cAMP-dependent, catalytic, beta

chr1_+_84767288 0.656 NM_001134663
SAMD13
sterile alpha motif domain containing 13
chr3_+_107096187 0.648 NM_032600
CCDC54
coiled-coil domain containing 54
chr9_+_127054246 0.639 NM_001166170
NM_001166171
NEK6

NIMA (never in mitosis gene a)-related kinase 6

chr10_+_94594469 0.634 NM_001013848
EXOC6
exocyst complex component 6
chr14_-_74551073 0.628 ALDH6A1
aldehyde dehydrogenase 6 family, member A1
chr17_+_58677603 0.609 PPM1D
protein phosphatase, Mg2+/Mn2+ dependent, 1D
chr9_-_98268866 0.608 PTCH1
patched 1
chr13_+_103459495 0.586 NM_001204425
BIVM-ERCC5
BIVM
BIVM-ERCC5 readthrough
basic, immunoglobulin-like variable motif containing
chr12_-_10022457 0.584 NM_005127
CLEC2B
C-type lectin domain family 2, member B
chr17_+_48172100 0.582 NM_001199898
PDK2
pyruvate dehydrogenase kinase, isozyme 2
chr11_+_60552820 0.575 NM_206893
MS4A10
membrane-spanning 4-domains, subfamily A, member 10
chr17_-_5138049 0.564 NM_207103
SCIMP
SLP adaptor and CSK interacting membrane protein
chr12_+_9142136 0.563 NM_005810
KLRG1
killer cell lectin-like receptor subfamily G, member 1
chr15_-_40600118 0.558 NM_004573
PLCB2
phospholipase C, beta 2
chr17_+_58755158 0.558 NM_001099432
NM_017679
BCAS3

breast carcinoma amplified sequence 3

chr20_+_16728997 0.558 NM_020157
OTOR
otoraplin
chr12_-_76425375 0.555 NM_007350
PHLDA1
pleckstrin homology-like domain, family A, member 1
chr5_+_68788118 0.555 NM_002538
OCLN
occludin
chrX_+_100333835 0.551 NM_021637
TMEM35
transmembrane protein 35
chr14_+_65877309 0.551 NM_004480
NM_178155
NM_178156
FUT8


fucosyltransferase 8 (alpha (1,6) fucosyltransferase)


chr19_-_48752921 0.550 NM_001184901
NM_001184903
NM_014959
CARD8


caspase recruitment domain family, member 8


chr10_-_105110823 0.550 PCGF6
polycomb group ring finger 6
chr3_-_168864325 0.549 NM_001105078
MECOM
MDS1 and EVI1 complex locus
chr2_+_179184970 0.548 NM_145739
OSBPL6
oxysterol binding protein-like 6
chr1_+_207277577 0.545 NM_000715
C4BPA
complement component 4 binding protein, alpha
chr10_-_105110890 0.542 NM_001011663
NM_032154
PCGF6

polycomb group ring finger 6

chr14_+_74551655 0.532 NM_001024674
LIN52
lin-52 homolog (C. elegans)
chr13_-_41240607 0.527 NM_002015
FOXO1
forkhead box O1
chr10_-_93392744 0.524 PPP1R3C
protein phosphatase 1, regulatory subunit 3C
chr10_+_102756829 0.520 NM_032429
LZTS2
leucine zipper, putative tumor suppressor 2
chr7_-_122635753 0.517 NM_016945
TAS2R16
taste receptor, type 2, member 16
chr15_-_40600025 0.512 PLCB2
phospholipase C, beta 2
chr13_+_53035227 0.511 CKAP2
cytoskeleton associated protein 2
chr12_+_20963637 0.507 NM_019844
SLCO1B3
solute carrier organic anion transporter family, member 1B3
chr1_+_173684061 0.507 NM_014458
KLHL20
kelch-like 20 (Drosophila)
chr2_+_109223600 0.500 NM_001193482
LIMS1
LIM and senescent cell antigen-like domains 1
chr19_-_58864820 0.499 NM_130786
A1BG
alpha-1-B glycoprotein
chr2_+_38155901 0.499 NM_001170792
FAM82A1
family with sequence similarity 82, member A1
chr1_+_74701070 0.497 NM_015978
TNNI3K
TNNI3 interacting kinase
chr4_-_123542165 0.495 NM_001207006
NM_021803
IL21

interleukin 21

chr7_+_150382783 0.492 NM_015660
GIMAP2
GTPase, IMAP family member 2
chr6_-_42016383 0.492 CCND3
cyclin D3
chr19_-_51141301 0.491 NM_032298
SYT3
synaptotagmin III
chr18_+_29769986 0.490 NM_005925
MEP1B
meprin A, beta
chr6_+_17600504 0.487 NM_016255
FAM8A1
family with sequence similarity 8, member A1
chr7_+_77469446 0.486 NM_001127357
NM_001127359
NM_020432
PHTF2


putative homeodomain transcription factor 2


chr2_-_165478357 0.484 NM_004490
GRB14
growth factor receptor-bound protein 14
chr18_-_53068755 0.483 TCF4
transcription factor 4
chr10_-_93392857 0.479 NM_005398
PPP1R3C
protein phosphatase 1, regulatory subunit 3C
chr3_-_58522873 0.478 NM_003500
ACOX2
acyl-CoA oxidase 2, branched chain
chr1_+_40862471 0.477 NM_001198980
SMAP2
small ArfGAP2
chr1_-_186649421 0.471 NM_000963
PTGS2
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
chr14_+_50234783 0.468 NM_014315
KLHDC2
kelch domain containing 2
chr2_-_219031646 0.465 NM_000634
CXCR1
chemokine (C-X-C motif) receptor 1
chr8_+_74903563 0.460 NM_001195797
NM_015364
LY96

lymphocyte antigen 96

chr3_+_98451537 0.458 NM_006100
ST3GAL6
ST3 beta-galactoside alpha-2,3-sialyltransferase 6
chr2_+_86947387 0.458 NM_022780
RMND5A
required for meiotic nuclear division 5 homolog A (S. cerevisiae)
chr14_+_50234907 0.455 KLHDC2
kelch domain containing 2
chr10_-_50732142 0.453 NM_170753
PGBD3
piggyBac transposable element derived 3
chr20_+_45338125 0.451 NM_030777
SLC2A10
solute carrier family 2 (facilitated glucose transporter), member 10
chr2_+_1417232 0.451 NM_000547
NM_001206744
NM_001206745
NM_175719
TPO



thyroid peroxidase



chr17_-_7082559 0.449 ASGR1
asialoglycoprotein receptor 1
chr1_+_246729818 0.448 CNST
consortin, connexin sorting protein
chr1_-_57431620 0.447 NM_000066
C8B
complement component 8, beta polypeptide
chr19_+_18111923 0.447 NM_001025604
ARRDC2
arrestin domain containing 2
chr5_-_39424930 0.446 DAB2
disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)
chr9_-_35812143 0.445 NM_001039592
NM_172312
SPAG8

sperm associated antigen 8

chr9_-_124984018 0.438 NM_001242335
LHX6
LIM homeobox 6
chr5_+_68800003 0.435 NM_001205255
OCLN
occludin
chr11_+_113931228 0.430 NM_001018011
ZBTB16
zinc finger and BTB domain containing 16
chr17_-_7082654 0.428 NM_001197216
NM_001671
ASGR1

asialoglycoprotein receptor 1

chr14_+_100563817 0.425 EVL
Enah/Vasp-like
chr10_-_105110844 0.421 PCGF6
polycomb group ring finger 6
chr15_-_40599872 0.415 PLCB2
phospholipase C, beta 2
chr17_+_11786218 0.412 NM_004662
DNAH9
dynein, axonemal, heavy chain 9
chr10_-_49482912 0.412 NM_001018071
FRMPD2
FERM and PDZ domain containing 2
chr10_+_5136589 0.411 AKR1C3
aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)
chr9_+_134000939 0.410 NM_005085
NUP214
nucleoporin 214kDa
chr3_+_23987514 0.409 NM_001145425
NR1D2
nuclear receptor subfamily 1, group D, member 2
chr2_-_87248942 0.407 NM_002665
NM_001032392
PLGLB2
PLGLB1
plasminogen-like B2
plasminogen-like B1
chr3_+_132036210 0.406 NM_001099
NM_001134194
ACPP

acid phosphatase, prostate

chr2_-_170430312 0.406 NM_024622
FASTKD1
FAST kinase domains 1
chr6_-_42016609 0.406 NM_001136017
NM_001136126
CCND3

cyclin D3

chr8_+_79428335 0.404 NM_006823
NM_181839
PKIA

protein kinase (cAMP-dependent, catalytic) inhibitor alpha

chr15_+_67000929 0.403 NM_001142861
SMAD6
SMAD family member 6
chr12_-_86229981 0.401 RASSF9
Ras association (RalGDS/AF-6) domain family (N-terminal) member 9
chr17_+_3377346 0.399 NM_001128085
ASPA
aspartoacylase
chr10_-_125853102 0.399 CHST15
carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15
chr5_+_140579182 0.398 NM_018931
PCDHB11
protocadherin beta 11
chr2_+_86947429 0.396 RMND5A
required for meiotic nuclear division 5 homolog A (S. cerevisiae)
chr2_+_220042948 0.394 FAM134A
family with sequence similarity 134, member A
chr8_-_110655418 0.394 NM_001099756
SYBU
syntabulin (syntaxin-interacting)
chr5_+_59784004 0.394 PART1
prostate androgen-regulated transcript 1 (non-protein coding)
chr1_+_84630374 0.390 PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr6_-_112575880 0.389 LAMA4
laminin, alpha 4
chr8_-_93107881 0.389 NM_001198625
NM_001198626
NM_001198627
NM_001198631
NM_001198634
NM_001198679
RUNX1T1





runt-related transcription factor 1; translocated to, 1 (cyclin D-related)





chr18_+_61575203 0.389 SERPINB10
serpin peptidase inhibitor, clade B (ovalbumin), member 10
chr2_+_175260505 0.387 SCRN3
secernin 3
chr1_-_24469571 0.387 NM_021258
IL22RA1
interleukin 22 receptor, alpha 1
chr2_+_175260455 0.387 NM_001193528
NM_024583
SCRN3

secernin 3

chr10_+_23728197 0.384 NM_001145373
OTUD1
OTU domain containing 1
chr1_+_61542928 0.383 NM_001145511
NFIA
nuclear factor I/A
chr10_+_5136556 0.383 NM_003739
AKR1C3
aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)
chr6_+_43027628 0.383 NM_201523
KLC4
kinesin light chain 4
chrX_-_63005212 0.379 NM_001173479
ARHGEF9
Cdc42 guanine nucleotide exchange factor (GEF) 9
chr5_-_180076616 0.378 NM_002020
NM_182925
FLT4

fms-related tyrosine kinase 4

chr20_-_17539480 0.376 NM_001161705
BFSP1
beaded filament structural protein 1, filensin
chr6_-_160679789 0.375 NM_003058
SLC22A2
solute carrier family 22 (organic cation transporter), member 2
chr2_+_1418179 0.374 NM_175721
NM_175722
TPO

thyroid peroxidase

chr4_-_16900348 0.374 NM_001130834
NM_001290
LDB2

LIM domain binding 2

chr15_+_72978519 0.372 NM_001252678
NM_033028
BBS4

Bardet-Biedl syndrome 4

chr4_+_36285643 0.371 NM_001170700
DTHD1
death domain containing 1
chr10_-_5045967 0.370 NM_001135241
AKR1C2
aldo-keto reductase family 1, member C2 (dihydrodiol dehydrogenase 2; bile acid binding protein; 3-alpha hydroxysteroid dehydrogenase, type III)
chr10_-_50396380 0.367 NM_001010863
C10orf128
chromosome 10 open reading frame 128
chr1_-_247697140 0.367 NM_198074
OR2C3
olfactory receptor, family 2, subfamily C, member 3
chr5_+_150157507 0.366 NM_032947
C5orf62
chromosome 5 open reading frame 62
chr2_+_86947570 0.365 RMND5A
required for meiotic nuclear division 5 homolog A (S. cerevisiae)
chr6_-_112575766 0.365 NM_001105206
NM_001105207
NM_001105208
NM_001105209
NM_002290
LAMA4




laminin, alpha 4




chr5_-_180076572 0.364 FLT4
fms-related tyrosine kinase 4
chr13_-_48987652 0.364 NM_001162498
LPAR6
lysophosphatidic acid receptor 6
chr6_-_56407681 0.360


chr4_-_16900256 0.359 LDB2
LIM domain binding 2
chr17_-_39334439 0.359 NM_033062
KRTAP4-2
keratin associated protein 4-2
chr10_+_5136613 0.358 AKR1C3
aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)
chr4_-_16900028 0.355 LDB2
LIM domain binding 2
chr2_+_191301020 0.354 MFSD6
major facilitator superfamily domain containing 6
chr17_+_3379295 0.349 NM_000049
ASPA
aspartoacylase
chr2_-_87303105 0.346 LOC285074
anaphase promoting complex subunit 1 pseudogene
chr5_+_131892556 0.345 NM_005732
RAD50
RAD50 homolog (S. cerevisiae)
chr15_-_65412175 0.342 PDCD7
programmed cell death 7
chr6_+_44244465 0.341 TMEM151B
transmembrane protein 151B
chr17_+_72427535 0.339 NM_022036
GPRC5C
G protein-coupled receptor, family C, group 5, member C
chr3_-_15839674 0.337 NM_001195098
ANKRD28
ankyrin repeat domain 28
chr1_+_84630014 0.337 NM_001242857
NM_001242858
NM_001242859
PRKACB


protein kinase, cAMP-dependent, catalytic, beta


chr18_-_53071225 0.336 NM_001243232
TCF4
transcription factor 4
chr1_+_82266081 0.336 NM_012302
LPHN2
latrophilin 2
chr1_+_207002221 0.334 NM_013371
IL19
interleukin 19
chr8_-_77912296 0.333 NM_000318
NM_001079867
PEX2

peroxisomal biogenesis factor 2

chr1_+_246729638 0.331 NM_001139459
NM_152609
CNST

consortin, connexin sorting protein

chrX_-_135863502 0.331 NM_004840
ARHGEF6
Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
chr5_+_140220811 0.330 NM_018911
NM_031856
PCDHA8

protocadherin alpha 8

chr4_+_155484131 0.329 NM_001184741
NM_005141
FGB

fibrinogen beta chain

chr3_-_183273407 0.329 NM_130446
KLHL6
kelch-like 6 (Drosophila)
chr2_-_142889269 0.327 NM_018557
LRP1B
low density lipoprotein receptor-related protein 1B
chr5_+_54398473 0.327 NM_006144
GZMA
granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3)
chr6_+_26501448 0.327 NM_001732
BTN1A1
butyrophilin, subfamily 1, member A1
chr3_+_132316080 0.323 NM_016557
CCRL1
chemokine (C-C motif) receptor-like 1
chr3_-_165555252 0.319 NM_000055
BCHE
butyrylcholinesterase
chr19_+_41699076 0.317 NM_030622
CYP2S1
cytochrome P450, family 2, subfamily S, polypeptide 1
chr14_+_102276125 0.316 NM_002719
NM_178586
NM_178587
PPP2R5C


protein phosphatase 2, regulatory subunit B', gamma


chr14_-_106714594 0.316



Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Gene overrepresentation in function category:

enrichment   p-value GO term description
4.10 1.35e-02 GO:0005097 Rab GTPase activator activity