Motif ID: GAGGUAG

Z-value: 1.256


Mature miRNA associated with seed GAGGUAG:

NamemiRBase Accession
hsa-let-7a MIMAT0000062
hsa-let-7b MIMAT0000063
hsa-let-7c MIMAT0000064
hsa-let-7d MIMAT0000065
hsa-let-7e MIMAT0000066
hsa-let-7f MIMAT0000067
hsa-let-7g MIMAT0000414
hsa-let-7i MIMAT0000415
hsa-miR-4458 MIMAT0018980
hsa-miR-4500 MIMAT0019036
hsa-miR-98 MIMAT0000096



Activity profile for motif GAGGUAG.

activity profile for motif GAGGUAG


Sorted Z-values histogram for motif GAGGUAG

Sorted Z-values for motif GAGGUAG



Network of associatons between targets according to the STRING database.



First level regulatory network of GAGGUAG

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr8_-_22549901 3.212 NM_001199880
EGR3
early growth response 3
chr8_-_22550708 3.131 NM_004430
EGR3
early growth response 3
chr8_-_22550057 3.129 NM_001199881
EGR3
early growth response 3
chr8_-_93029864 2.900 NM_175636
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr8_-_93107881 2.818 NM_001198625
NM_001198626
NM_001198627
NM_001198631
NM_001198634
NM_001198679
RUNX1T1





runt-related transcription factor 1; translocated to, 1 (cyclin D-related)





chr8_-_93111915 2.783 NM_001198628
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr1_-_92371558 2.704 NM_001195684
TGFBR3
transforming growth factor, beta receptor III
chr8_-_93107442 2.647 NM_001198629
NM_001198630
NM_001198632
NM_175635
RUNX1T1



runt-related transcription factor 1; translocated to, 1 (cyclin D-related)



chr1_-_92351613 2.624 NM_001195683
NM_003243
TGFBR3

transforming growth factor, beta receptor III

chr8_-_93115453 2.602 NM_001198633
NM_175634
RUNX1T1

runt-related transcription factor 1; translocated to, 1 (cyclin D-related)

chr14_+_24867926 2.534 NM_025081
NYNRIN
NYN domain and retroviral integrase containing
chr8_-_93075190 2.247 NM_004349
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr5_-_88179278 2.200 NM_001193350
NM_002397
MEF2C

myocyte enhancer factor 2C

chr5_-_172198160 2.073 NM_004417
DUSP1
dual specificity phosphatase 1
chr7_+_94023872 2.027 NM_000089
COL1A2
collagen, type I, alpha 2
chr15_+_57668702 2.027 NM_001252335
NM_032866
CGNL1

cingulin-like 1

chr5_-_88199868 1.989 NM_001131005
NM_001193347
MEF2C

myocyte enhancer factor 2C

chr7_-_20826503 1.951 NM_182700
NM_198956
SP8

Sp8 transcription factor

chr2_+_12856813 1.950 NM_021643
TRIB2
tribbles homolog 2 (Drosophila)
chr8_-_125384916 1.874 NM_194291
TMEM65
transmembrane protein 65
chr2_-_152684963 1.870 NM_001037174
NM_012097
NM_177985
ARL5A


ADP-ribosylation factor-like 5A


chr1_-_45672225 1.869 NM_020883
ZSWIM5
zinc finger, SWIM-type containing 5
chr3_+_39851028 1.851 NM_015460
MYRIP
myosin VIIA and Rab interacting protein
chr11_+_59522531 1.817 NM_001178040
NM_004177
STX3

syntaxin 3

chr8_-_124544376 1.698 NM_148177
FBXO32
F-box protein 32
chr8_-_124553448 1.690 NM_001242463
NM_058229
FBXO32

F-box protein 32

chr2_-_39664129 1.663 NM_003618
MAP4K3
mitogen-activated protein kinase kinase kinase kinase 3
chr3_-_15900928 1.643 NM_015199
ANKRD28
ankyrin repeat domain 28
chr3_+_16216155 1.640 NM_054110
GALNTL2
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 2
chr20_+_37434294 1.627 NM_001172735
NM_015568
PPP1R16B

protein phosphatase 1, regulatory subunit 16B

chr2_-_222436996 1.614 NM_004438
EPHA4
EPH receptor A4
chr10_-_50747080 1.582 NM_000124
ERCC6
PGBD3
excision repair cross-complementing rodent repair deficiency, complementation group 6
piggyBac transposable element derived 3
chr9_+_115513050 1.544 NM_001012994
SNX30
sorting nexin family member 30
chr1_-_225616556 1.540 NM_194442
LBR
lamin B receptor
chr2_-_74667553 1.538 NM_001015056
NM_033046
RTKN

rhotekin

chr5_-_88119604 1.534 NM_001193348
NM_001193349
MEF2C

myocyte enhancer factor 2C

chr13_-_52585472 1.512 NM_000053
NM_001005918
NM_001243182
ATP7B


ATPase, Cu++ transporting, beta polypeptide


chr7_+_22766765 1.510 NM_000600
IL6
interleukin 6 (interferon, beta 2)
chr18_+_6834431 1.462 NM_001010000
ARHGAP28
Rho GTPase activating protein 28
chr9_+_90112754 1.439 NM_004938
DAPK1
death-associated protein kinase 1
chr7_-_27205148 1.402 NM_152739
HOXA9
homeobox A9
chr12_+_13197284 1.402 NM_020853
KIAA1467
KIAA1467
chr9_-_140196702 1.391 NM_001004354
NRARP
NOTCH-regulated ankyrin repeat protein
chr8_-_127570710 1.387 NM_174911
FAM84B
family with sequence similarity 84, member B
chr9_+_123850573 1.379 NM_007018
CNTRL
centriolin
chr3_-_15839674 1.377 NM_001195098
ANKRD28
ankyrin repeat domain 28
chr15_+_42867708 1.372 NM_020759
STARD9
StAR-related lipid transfer (START) domain containing 9
chr13_+_39612440 1.333 NM_001012754
NM_001017370
NHLRC3

NHL repeat containing 3

chr1_+_12227050 1.319 NM_001066
TNFRSF1B
tumor necrosis factor receptor superfamily, member 1B
chr2_-_74669055 1.315 NM_001015055
RTKN
rhotekin
chr2_-_99347588 1.314 NM_012214
MGAT4A
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
chr1_+_203274646 1.241 NM_006763
BTG2
BTG family, member 2
chr1_+_164528586 1.236 NM_001204961
NM_001204963
NM_002585
PBX1


pre-B-cell leukemia homeobox 1


chr10_+_72238529 1.215 NM_014431
KIAA1274
KIAA1274
chr15_-_56035176 1.193 NM_173814
PRTG
protogenin
chr1_-_225615787 1.176 NM_002296
LBR
lamin B receptor
chr6_-_80656870 1.158 NM_022726
ELOVL4
ELOVL fatty acid elongase 4
chr8_-_82754427 1.158 NM_022133
NM_152836
NM_152837
SNX16


sorting nexin 16


chr16_+_14013989 1.150 NM_005236
ERCC4
excision repair cross-complementing rodent repair deficiency, complementation group 4
chr2_+_113403433 1.147 NM_005415
SLC20A1
solute carrier family 20 (phosphate transporter), member 1
chr3_+_150126705 1.138 NM_014779
TSC22D2
TSC22 domain family, member 2
chr5_-_72861376 1.133 NM_023039
ANKRA2
ankyrin repeat, family A (RFXANK-like), 2
chr6_+_143999058 1.133 NM_001100164
NM_001100165
PHACTR2

phosphatase and actin regulator 2

chr1_+_33722158 1.096 NM_152493
ZNF362
zinc finger protein 362
chrX_-_33229428 1.093 NM_004006
DMD
dystrophin
chr6_+_37321719 1.089 NM_003958
NM_183078
RNF8

ring finger protein 8

chr3_-_56717132 1.087 NM_001112736
FAM208A
family with sequence similarity 208, member A
chr5_+_61714710 1.076 NM_001134779
IPO11
importin 11
chr3_+_49208979 1.066 NM_173546
KLHDC8B
kelch domain containing 8B
chr9_-_129884998 1.063 NM_012098
ANGPTL2
angiopoietin-like 2
chr5_+_176560056 1.054 NM_172349
NSD1
nuclear receptor binding SET domain protein 1
chr11_-_66115016 1.049 NM_006876
B3GNT1
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 1
chr1_+_204042191 1.048 NM_005686
SOX13
SRY (sex determining region Y)-box 13
chr6_-_134373618 1.046 NM_145176
SLC2A12
solute carrier family 2 (facilitated glucose transporter), member 12
chr6_+_143929316 1.031 NM_001100166
NM_014721
PHACTR2

phosphatase and actin regulator 2

chr8_-_29206321 1.027 NM_057158
DUSP4
dual specificity phosphatase 4
chr3_-_15798057 1.022 NM_001195099
ANKRD28
ankyrin repeat domain 28
chr13_-_110438896 1.019 NM_003749
IRS2
insulin receptor substrate 2
chr2_+_177053306 1.019 NM_024501
HOXD1
homeobox D1
chr5_+_61708565 1.015 NM_016338
IPO11
importin 11
chr12_+_79257772 1.010 NM_001135805
SYT1
synaptotagmin I
chr12_+_79439432 1.007 NM_001135806
SYT1
synaptotagmin I
chr2_+_32390902 0.998 NM_001193513
NM_001193514
NM_001193515
NM_017964
SLC30A6



solute carrier family 30 (zinc transporter), member 6



chr5_+_42549657 0.985 NM_001242404
GHR
growth hormone receptor
chr5_+_42565963 0.979 NM_001242460
NM_001242461
NM_001242462
GHR


growth hormone receptor


chr20_+_11871364 0.977 NM_181443
BTBD3
BTB (POZ) domain containing 3
chr1_+_110753313 0.967 NM_001039574
NM_004978
KCNC4

potassium voltage-gated channel, Shaw-related subfamily, member 4

chr10_-_72141347 0.966 NM_207119
LRRC20
leucine rich repeat containing 20
chr17_-_60005309 0.966 NM_020748
INTS2
integrator complex subunit 2
chr3_+_194406614 0.963 NM_153690
FAM43A
family with sequence similarity 43, member A
chr9_-_126030854 0.962 NM_001171137
STRBP
spermatid perinuclear RNA binding protein
chr9_-_99145991 0.960 NM_007001
SLC35D2
solute carrier family 35, member D2
chr5_+_42425093 0.956 NM_001242401
GHR
growth hormone receptor
chr5_+_42550181 0.947 NM_001242405
GHR
growth hormone receptor
chr17_+_5031686 0.946 NM_004505
USP6
ubiquitin specific peptidase 6 (Tre-2 oncogene)
chr1_+_65210724 0.946 NM_018211
RAVER2
ribonucleoprotein, PTB-binding 2
chr19_+_4910339 0.943 NM_013282
UHRF1
ubiquitin-like with PHD and ring finger domains 1
chr11_+_44785975 0.926 NM_130783
TSPAN18
tetraspanin 18
chr10_-_81205091 0.926 NM_153367
ZCCHC24
zinc finger, CCHC domain containing 24
chrX_-_32173585 0.925 NM_004013
NM_004020
NM_004021
NM_004022
NM_004023
DMD




dystrophin




chr3_-_56698073 0.919 NM_015224
FAM208A
family with sequence similarity 208, member A
chr17_-_16118789 0.919 NM_006311
NCOR1
nuclear receptor corepressor 1
chr9_-_126030792 0.918 NM_018387
STRBP
spermatid perinuclear RNA binding protein
chr8_-_17555158 0.917 NM_020749
MTUS1
microtubule associated tumor suppressor 1
chr6_+_71123105 0.915 NM_001105531
NM_020819
FAM135A

family with sequence similarity 135, member A

chr11_-_27494232 0.914 NM_018490
LGR4
leucine-rich repeat containing G protein-coupled receptor 4
chr16_-_4166185 0.912 NM_001116
ADCY9
adenylate cyclase 9
chr12_+_79258448 0.910 NM_005639
SYT1
synaptotagmin I
chr5_+_42424553 0.906 NM_001242399
NM_001242400
GHR

growth hormone receptor

chr4_-_102268626 0.900 NM_000944
NM_001130691
NM_001130692
PPP3CA


protein phosphatase 3, catalytic subunit, alpha isozyme


chr9_-_10612722 0.900 NM_002839
PTPRD
protein tyrosine phosphatase, receptor type, D
chr10_-_72142344 0.899 NM_018205
NM_018239
LRRC20

leucine rich repeat containing 20

chr21_-_28217692 0.893 NM_006988
ADAMTS1
ADAM metallopeptidase with thrombospondin type 1 motif, 1
chr16_+_53088791 0.887 NM_025134
CHD9
chromodomain helicase DNA binding protein 9
chr9_-_8733893 0.885 NM_001040712
NM_001171025
NM_130391
NM_130392
NM_130393
PTPRD




protein tyrosine phosphatase, receptor type, D




chr11_+_86748870 0.881 NM_001168724
NM_022918
TMEM135

transmembrane protein 135

chr14_+_24899139 0.881 NM_015299
KHNYN
KH and NYN domain containing
chr5_+_42548144 0.881 NM_001242402
GHR
growth hormone receptor
chrX_-_33146543 0.867 NM_004010
NM_004009
DMD

dystrophin

chr8_-_17658385 0.864 NM_001001924
NM_001001925
MTUS1

microtubule associated tumor suppressor 1

chr5_+_42548314 0.859 NM_001242403
GHR
growth hormone receptor
chr9_+_128510477 0.856 NM_001134778
PBX3
pre-B-cell leukemia homeobox 3
chr6_-_8064642 0.853 NM_001199322
NM_001199323
NM_201280
MUTED


muted homolog (mouse)


chr3_+_183873253 0.852 NM_004423
DVL3
dishevelled, dsh homolog 3 (Drosophila)
chr16_+_18995255 0.851 NM_024847
TMC7
transmembrane channel-like 7
chr3_-_69062744 0.851 NM_173654
C3orf64
chromosome 3 open reading frame 64
chr8_-_17580024 0.851 NM_001166393
MTUS1
microtubule associated tumor suppressor 1
chr8_-_17579729 0.842 NM_001001931
MTUS1
microtubule associated tumor suppressor 1
chr5_-_55008125 0.836 NM_173514
SLC38A9
solute carrier family 38, member 9
chr8_+_74206772 0.829 NM_172037
RDH10
retinol dehydrogenase 10 (all-trans)
chr11_+_134094545 0.828 NM_052875
VPS26B
vacuolar protein sorting 26 homolog B (S. pombe)
chr3_-_132441302 0.826 NM_153240
NPHP3-ACAD11
NPHP3
NPHP3-ACAD11 readthrough
nephronophthisis 3 (adolescent)
chrX_-_31526414 0.822 NM_004014
DMD
dystrophin
chrX_-_32430370 0.818 NM_004011
NM_004012
DMD

dystrophin

chr6_+_71136141 0.817 NM_001162529
FAM135A
family with sequence similarity 135, member A
chr8_-_29207795 0.817 NM_001394
DUSP4
dual specificity phosphatase 4
chr8_-_12973752 0.816 NM_001164271
DLC1
deleted in liver cancer 1
chr1_+_161129229 0.805 NM_001014443
NM_012475
USP21

ubiquitin specific peptidase 21

chr1_-_204121144 0.802 NM_018208
ETNK2
ethanolamine kinase 2
chr10_-_102279590 0.798 NM_015490
SEC31B
SEC31 homolog B (S. cerevisiae)
chr13_-_96296919 0.797 NM_014934
NM_198968
DZIP1

DAZ interacting protein 1

chr16_+_18995508 0.796 NM_001160364
TMC7
transmembrane channel-like 7
chr2_-_70475563 0.796 NM_022037
NM_022173
TIA1

TIA1 cytotoxic granule-associated RNA binding protein

chr9_+_132597651 0.795 NM_001110303
NM_006676
USP20

ubiquitin specific peptidase 20

chr14_-_89883306 0.793 NM_005197
FOXN3
forkhead box N3
chr1_-_179112178 0.792 NM_001136000
NM_001168239
NM_005158
ABL2


v-abl Abelson murine leukemia viral oncogene homolog 2


chr13_-_99174251 0.789 NM_003576
STK24
serine/threonine kinase 24
chr12_+_111843743 0.786 NM_005475
SH2B3
SH2B adaptor protein 3
chr9_+_132597728 0.781 NM_001008563
USP20
ubiquitin specific peptidase 20
chr13_-_52733669 0.780 NM_152720
NEK3
NIMA (never in mitosis gene a)-related kinase 3
chr5_+_42423811 0.779 NM_000163
GHR
growth hormone receptor
chr13_-_33780142 0.778 NM_001243474
NM_052851
STARD13

StAR-related lipid transfer (START) domain containing 13

chr13_-_33760215 0.776 NM_001243466
NM_178007
STARD13

StAR-related lipid transfer (START) domain containing 13

chr4_+_106067754 0.775 NM_001127208
TET2
tet methylcytosine dioxygenase 2
chr20_-_62601140 0.769 NM_020713
ZNF512B
zinc finger protein 512B
chr12_-_59313304 0.769 NM_001136051
LRIG3
leucine-rich repeats and immunoglobulin-like domains 3
chr5_+_41904459 0.767 NM_175921
C5orf51
chromosome 5 open reading frame 51
chr13_-_52733995 0.766 NM_001146099
NM_002498
NEK3

NIMA (never in mitosis gene a)-related kinase 3

chr12_-_59314069 0.760 NM_153377
LRIG3
leucine-rich repeats and immunoglobulin-like domains 3
chr5_+_42565562 0.754 NM_001242406
GHR
growth hormone receptor
chr14_+_57857261 0.752 NM_001011713
NAA30
N(alpha)-acetyltransferase 30, NatC catalytic subunit
chr7_+_74072007 0.751 NM_001163636
NM_001518
NM_032999
NM_033000
NM_033001
GTF2I




general transcription factor IIi




chr9_+_128509616 0.749 NM_006195
PBX3
pre-B-cell leukemia homeobox 3
chr17_+_61699786 0.741 NM_002401
NM_203351
MAP3K3

mitogen-activated protein kinase kinase kinase 3

chr20_+_11898536 0.740 NM_014962
BTBD3
BTB (POZ) domain containing 3
chr5_+_150157507 0.727 NM_032947
C5orf62
chromosome 5 open reading frame 62
chr14_+_100150596 0.723 NM_006668
CYP46A1
cytochrome P450, family 46, subfamily A, polypeptide 1
chr13_-_99229226 0.722 NM_001032296
STK24
serine/threonine kinase 24
chr4_-_18023358 0.719 NM_001166139
NM_153686
LCORL

ligand dependent nuclear receptor corepressor-like

chr12_+_56915587 0.713 NM_002898
RBMS2
RNA binding motif, single stranded interacting protein 2
chr1_-_6296034 0.706 NM_012405
ICMT
isoprenylcysteine carboxyl methyltransferase
chr2_+_148602569 0.703 NM_001616
ACVR2A
activin A receptor, type IIA
chr17_-_58469577 0.702 NM_032582
USP32
ubiquitin specific peptidase 32
chr21_+_27107322 0.695 NM_002040
GABPA
GA binding protein transcription factor, alpha subunit 60kDa
chr3_+_107241782 0.694 NM_001142568
NM_020235
BBX

bobby sox homolog (Drosophila)

chr8_-_12990731 0.690 NM_006094
DLC1
deleted in liver cancer 1
chr16_+_66914380 0.687 NM_020786
PDP2
pyruvate dehyrogenase phosphatase catalytic subunit 2
chrX_-_33357725 0.685 NM_000109
DMD
dystrophin
chr19_+_4909447 0.681 NM_001048201
UHRF1
ubiquitin-like with PHD and ring finger domains 1
chr3_-_185542807 0.681 NM_001007225
NM_006548
IGF2BP2

insulin-like growth factor 2 mRNA binding protein 2

chr21_+_27107257 0.676 NM_001197297
GABPA
GA binding protein transcription factor, alpha subunit 60kDa
chr10_+_102106771 0.675 NM_005063
SCD
stearoyl-CoA desaturase (delta-9-desaturase)
chr9_-_72287097 0.671 NM_001163
APBA1
amyloid beta (A4) precursor protein-binding, family A, member 1
chr12_-_42538432 0.666 NM_001099650
NM_173601
GXYLT1

glucoside xylosyltransferase 1

chr12_-_48745020 0.663 NM_001172682
ZNF641
zinc finger protein 641
chrX_-_31284946 0.661 NM_004015
NM_004016
NM_004017
NM_004018
NM_004019
DMD




dystrophin




chr15_-_49338496 0.660 NM_001193489
NM_014701
SECISBP2L

SECIS binding protein 2-like

chr12_+_15475190 0.659 NM_002848
NM_030667
PTPRO

protein tyrosine phosphatase, receptor type, O

chr4_-_128887092 0.658 NM_152778
MFSD8
major facilitator superfamily domain containing 8
chr17_-_65241305 0.658 NM_014877
HELZ
helicase with zinc finger
chr9_+_136325086 0.648 NM_001135775
NM_001242369
NM_001242370
NM_017586
C9orf7



chromosome 9 open reading frame 7



chr12_+_15699277 0.642 NM_030668
NM_030669
NM_030670
NM_030671
PTPRO



protein tyrosine phosphatase, receptor type, O



chr6_+_147525493 0.639 NM_001127715
NM_139244
STXBP5

syntaxin binding protein 5 (tomosyn)

chr17_-_58603492 0.635 NM_006380
APPBP2
amyloid beta precursor protein (cytoplasmic tail) binding protein 2
chr2_+_109335906 0.633 NM_006267
RANBP2
RAN binding protein 2
chr1_+_154377668 0.633 NM_000565
NM_001206866
NM_181359
IL6R


interleukin 6 receptor


chr7_-_6312137 0.632 NM_004227
CYTH3
cytohesin 3
chr1_-_165325951 0.629 NM_177398
LMX1A
LIM homeobox transcription factor 1, alpha
chr20_+_278200 0.627 NM_033089
ZCCHC3
zinc finger, CCHC domain containing 3
chr13_-_33859835 0.623 NM_178006
STARD13
StAR-related lipid transfer (START) domain containing 13

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.68 1.85e-03 GO:0006464 protein modification process
1.65 2.51e-03 GO:0043412 macromolecule modification

Nothing significant found in compartment category.

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.26 4.62e-02 GO:0003824 catalytic activity