Motif ID: GATA1..3.p2

Z-value: 1.270


Transcription factors associated with GATA1..3.p2:

Gene SymbolEntrez IDGene Name
GATA1 2623 GATA binding protein 1 (globin transcription factor 1)
GATA2 2624 GATA binding protein 2
GATA3 2625 GATA binding protein 3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.p-valuePlot
GATA1chrX_+_486449610.213.2e-01Click!
GATA2chr3_-_1282067040.116.0e-01Click!
GATA3chr10_+_8097350-0.106.2e-01Click!


Activity profile for motif GATA1..3.p2.

activity profile for motif GATA1..3.p2


Sorted Z-values histogram for motif GATA1..3.p2

Sorted Z-values for motif GATA1..3.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of GATA1..3.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr8_-_22550057 1.692 NM_001199881
 EGR3
early growth response 3
chr11_+_5410606 1.394 NM_001004756
 OR51M1
olfactory receptor, family 51, subfamily M, member 1
chr12_-_52779362 1.268 NM_033045
 KRT84
keratin 84
chr6_-_114384008 1.168 NM_153612
 HS3ST5
heparan sulfate (glucosamine) 3-O-sulfotransferase 5
chr16_+_3405888 1.143 NM_012368
 OR2C1
olfactory receptor, family 2, subfamily C, member 1
chr19_+_15160194 1.051 NM_012114
 CASP14
caspase 14, apoptosis-related cysteine peptidase
chr9_+_35829375 1.050 NM_001042590
 TMEM8B
transmembrane protein 8B
chrX_-_153236621 0.984 NM_005334
 HCFC1
host cell factor C1 (VP16-accessory protein)
chr2_-_60780767 0.896 BCL11A
B-cell CLL/lymphoma 11A (zinc finger protein)
chr19_+_50145369 0.894 NM_021228
 SCAF1
SR-related CTD-associated factor 1
chr2_+_162272892 0.884 TBR1
T-box, brain, 1
chr8_-_22550708 0.836 NM_004430
 EGR3
early growth response 3
chr3_+_133494275 0.830 TF
transferrin
chr22_+_22385340 0.817


chr19_+_49376488 0.802 PPP1R15A
protein phosphatase 1, regulatory subunit 15A
chr17_-_62050200 0.795 NM_000334
 SCN4A
sodium channel, voltage-gated, type IV, alpha subunit
chr8_+_110099652 0.787 NM_003301
 TRHR
thyrotropin-releasing hormone receptor
chr8_-_22549901 0.784 NM_001199880
 EGR3
early growth response 3
chr2_-_31352489 0.771 NM_001253827
 GALNT14
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 14 (GalNAc-T14)
chr16_+_89778242 0.751 LOC100128881
uncharacterized LOC100128881

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 53 entries
enrichment   p-value GO term description
1.76 3.04e-02 GO:0042391 regulation of membrane potential
1.58 2.32e-06 GO:0007268 synaptic transmission
1.58 1.73e-02 GO:0030168 platelet activation
1.57 4.10e-07 GO:0019226 transmission of nerve impulse
1.57 4.10e-07 GO:0035637 multicellular organismal signaling
1.54 1.07e-10 GO:0007267 cell-cell signaling
1.49 5.38e-12 GO:0007154 cell communication
1.43 1.01e-02 GO:0051094 positive regulation of developmental process
1.41 6.56e-07 GO:0022008 neurogenesis
1.40 5.06e-06 GO:0048699 generation of neurons
1.39 4.00e-04 GO:0030182 neuron differentiation
1.39 4.66e-03 GO:0048666 neuron development
1.39 2.75e-02 GO:0030001 metal ion transport
1.38 2.82e-11 GO:0007399 nervous system development
1.38 3.92e-02 GO:0048585 negative regulation of response to stimulus
1.38 4.47e-02 GO:0048858 cell projection morphogenesis
1.36 3.15e-02 GO:0006812 cation transport
1.35 9.41e-03 GO:0010628 positive regulation of gene expression
1.34 5.00e-04 GO:0006811 ion transport
1.34 3.61e-02 GO:0030030 cell projection organization

Gene overrepresentation in compartment category:

Showing 1 to 12 of 12 entries
enrichment   p-value GO term description
1.75 2.94e-03 GO:0034703 cation channel complex
1.63 3.10e-02 GO:0045211 postsynaptic membrane
1.59 3.44e-03 GO:0034702 ion channel complex
1.55 4.18e-06 GO:0045202 synapse
1.55 3.42e-04 GO:0044456 synapse part
1.50 7.23e-05 GO:0043005 neuron projection
1.34 4.41e-03 GO:0030054 cell junction
1.30 8.66e-04 GO:0042995 cell projection
1.19 1.66e-04 GO:0044459 plasma membrane part
1.19 2.62e-02 GO:0005856 cytoskeleton
1.10 3.15e-02 GO:0005886 plasma membrane
1.10 4.86e-02 GO:0071944 cell periphery

Gene overrepresentation in function category:

Showing 1 to 20 of 21 entries
enrichment   p-value GO term description
1.85 2.25e-02 GO:0015081 sodium ion transmembrane transporter activity
1.70 9.51e-03 GO:0046873 metal ion transmembrane transporter activity
1.66 3.00e-02 GO:0022843 voltage-gated cation channel activity
1.56 2.79e-04 GO:0022836 gated channel activity
1.51 5.52e-05 GO:0015267 channel activity
1.50 6.56e-05 GO:0022803 passive transmembrane transporter activity
1.48 4.55e-04 GO:0022838 substrate-specific channel activity
1.48 5.38e-04 GO:0005216 ion channel activity
1.46 4.58e-02 GO:0005261 cation channel activity
1.38 1.67e-03 GO:0008324 cation transmembrane transporter activity
1.37 7.52e-05 GO:0015075 ion transmembrane transporter activity
1.33 4.02e-03 GO:0043565 sequence-specific DNA binding
1.32 3.93e-04 GO:0022891 substrate-specific transmembrane transporter activity
1.31 1.97e-04 GO:0022857 transmembrane transporter activity
1.29 7.78e-04 GO:0022892 substrate-specific transporter activity
1.29 8.09e-04 GO:0001071 nucleic acid binding transcription factor activity
1.29 8.09e-04 GO:0003700 sequence-specific DNA binding transcription factor activity
1.29 8.26e-04 GO:0030528 transcription regulator activity
1.25 2.37e-03 GO:0005215 transporter activity
1.12 3.34e-10 GO:0005515 protein binding