Motif ID: GFI1.p2

Z-value: 1.307


Transcription factors associated with GFI1.p2:

Gene SymbolEntrez IDGene Name
GFI1 2672 growth factor independent 1 transcription repressor

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.p-valuePlot
GFI1chr1_-_929524290.087.2e-01Click!


Activity profile for motif GFI1.p2.

activity profile for motif GFI1.p2


Sorted Z-values histogram for motif GFI1.p2

Sorted Z-values for motif GFI1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of GFI1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr9_+_79093256 2.567 NM_001097635
 GCNT1
glucosaminyl (N-acetyl) transferase 1, core 2
chr14_+_58765209 2.421 NM_002892
NM_023000
NM_023001
 ARID4A


AT rich interactive domain 4A (RBP1-like)


chr20_-_62680880 2.331 NM_018419
 SOX18
SRY (sex determining region Y)-box 18
chr20_+_58508818 2.295 NM_001190826
 C20orf177
chromosome 20 open reading frame 177
chr1_-_45140117 2.239 TMEM53
transmembrane protein 53
chr17_-_47841517 2.180 NM_030802
 FAM117A
family with sequence similarity 117, member A
chr10_-_93392744 2.172 PPP1R3C
protein phosphatase 1, regulatory subunit 3C
chr10_-_93392857 2.163 NM_005398
 PPP1R3C
protein phosphatase 1, regulatory subunit 3C
chr7_-_148725500 1.898 PDIA4
protein disulfide isomerase family A, member 4
chr17_-_47841468 1.882 FAM117A
family with sequence similarity 117, member A
chr4_-_186300151 1.819 NM_018409
 LRP2BP
LRP2 binding protein
chr14_+_58765275 1.785 ARID4A
AT rich interactive domain 4A (RBP1-like)
chr14_-_91526912 1.754 NM_004755
NM_182398
 RPS6KA5

ribosomal protein S6 kinase, 90kDa, polypeptide 5

chr14_-_74416711 1.542 FAM161B
family with sequence similarity 161, member B
chr4_-_138453628 1.518 NM_019035
 PCDH18
protocadherin 18
chr1_-_45140062 1.479 NM_024587
 TMEM53
transmembrane protein 53
chr17_+_68165660 1.469 NM_000891
 KCNJ2
potassium inwardly-rectifying channel, subfamily J, member 2
chr1_+_164528586 1.459 NM_001204961
NM_001204963
NM_002585
 PBX1


pre-B-cell leukemia homeobox 1


chr19_-_14640048 1.452 DNAJB1
DnaJ (Hsp40) homolog, subfamily B, member 1
chr4_+_6271558 1.442 NM_001145853
NM_006005
 WFS1

Wolfram syndrome 1 (wolframin)


Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 32 entries
enrichment   p-value GO term description
2.66 6.81e-04 GO:0065004 protein-DNA complex assembly
2.60 7.88e-04 GO:0071824 protein-DNA complex subunit organization
1.91 2.19e-03 GO:0000087 M phase of mitotic cell cycle
1.85 9.33e-05 GO:0000279 M phase
1.84 2.19e-03 GO:0051301 cell division
1.83 1.92e-02 GO:0000280 nuclear division
1.83 1.92e-02 GO:0007067 mitosis
1.72 2.26e-03 GO:0006325 chromatin organization
1.71 4.76e-02 GO:0016568 chromatin modification
1.68 2.32e-04 GO:0051276 chromosome organization
1.63 3.85e-03 GO:0000278 mitotic cell cycle
1.61 8.73e-07 GO:0007049 cell cycle
1.60 1.37e-03 GO:0022403 cell cycle phase
1.58 2.72e-04 GO:0022402 cell cycle process
1.32 8.23e-04 GO:0006355 regulation of transcription, DNA-dependent
1.30 1.98e-03 GO:0051252 regulation of RNA metabolic process
1.29 1.37e-03 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.27 1.95e-03 GO:0071842 cellular component organization at cellular level
1.27 4.00e-03 GO:0010556 regulation of macromolecule biosynthetic process
1.26 1.12e-02 GO:0010468 regulation of gene expression

Gene overrepresentation in compartment category:

Showing 1 to 19 of 19 entries
enrichment   p-value GO term description
1.98 7.97e-04 GO:0000785 chromatin
1.98 1.01e-02 GO:0005819 spindle
1.72 1.94e-05 GO:0005694 chromosome
1.72 2.35e-04 GO:0044427 chromosomal part
1.47 1.57e-02 GO:0015630 microtubule cytoskeleton
1.46 2.23e-02 GO:0042175 nuclear membrane-endoplasmic reticulum network
1.46 2.24e-02 GO:0005789 endoplasmic reticulum membrane
1.44 1.72e-02 GO:0044432 endoplasmic reticulum part
1.33 1.71e-02 GO:0005654 nucleoplasm
1.25 3.30e-11 GO:0005634 nucleus
1.24 3.07e-02 GO:0044428 nuclear part
1.17 2.30e-12 GO:0043227 membrane-bounded organelle
1.17 2.32e-12 GO:0043231 intracellular membrane-bounded organelle
1.16 6.58e-13 GO:0043229 intracellular organelle
1.15 1.31e-12 GO:0043226 organelle
1.15 3.10e-03 GO:0044422 organelle part
1.15 3.45e-03 GO:0044446 intracellular organelle part
1.12 1.29e-10 GO:0044424 intracellular part
1.11 5.44e-10 GO:0005622 intracellular

Gene overrepresentation in function category:

Showing 1 to 9 of 9 entries
enrichment   p-value GO term description
1.31 5.21e-05 GO:0003677 DNA binding
1.29 1.87e-03 GO:0008270 zinc ion binding
1.25 1.01e-02 GO:0046914 transition metal ion binding
1.20 7.83e-04 GO:0043169 cation binding
1.20 1.05e-03 GO:0043167 ion binding
1.20 1.09e-03 GO:0046872 metal ion binding
1.20 6.10e-03 GO:0003676 nucleic acid binding
1.11 1.92e-02 GO:0005515 protein binding
1.07 2.13e-04 GO:0005488 binding