Motif ID: GGCAAGA

Z-value: 0.700


Mature miRNA associated with seed GGCAAGA:

NamemiRBase Accession
hsa-miR-31 MIMAT0000089



Activity profile for motif GGCAAGA.

activity profile for motif GGCAAGA


Sorted Z-values histogram for motif GGCAAGA

Sorted Z-values for motif GGCAAGA



Network of associatons between targets according to the STRING database.



First level regulatory network of GGCAAGA

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_+_65613771 1.077 NM_013410
AK4
adenylate kinase 4
chr1_+_65613211 1.052 NM_203464
NM_001005353
AK4

adenylate kinase 4

chr5_-_59189620 0.862 NM_001104631
PDE4D
phosphodiesterase 4D, cAMP-specific
chr5_-_59783885 0.771 NM_001165899
PDE4D
phosphodiesterase 4D, cAMP-specific
chr5_-_58882274 0.761 NM_006203
PDE4D
phosphodiesterase 4D, cAMP-specific
chr5_-_58571916 0.749 NM_001197220
PDE4D
phosphodiesterase 4D, cAMP-specific
chr5_-_58295758 0.706 NM_001197223
PDE4D
phosphodiesterase 4D, cAMP-specific
chr10_+_101419169 0.704 NM_020354
ENTPD7
ectonucleoside triphosphate diphosphohydrolase 7
chr5_-_58334936 0.699 NM_001197221
NM_001197222
PDE4D

phosphodiesterase 4D, cAMP-specific

chr5_-_58652671 0.692 NM_001197219
PDE4D
phosphodiesterase 4D, cAMP-specific
chr3_-_52090090 0.682 NM_001947
DUSP7
dual specificity phosphatase 7
chr5_-_59064437 0.679 NM_001197218
PDE4D
phosphodiesterase 4D, cAMP-specific
chr4_-_120549115 0.641 NM_033437
PDE5A
phosphodiesterase 5A, cGMP-specific
chr6_+_7107986 0.639 NM_001003698
NM_001003699
NM_001003700
RREB1


ras responsive element binding protein 1


chr4_-_41216455 0.628 NM_001166050
NM_004307
NM_173075
APBB2


amyloid beta (A4) precursor protein-binding, family B, member 2


chr6_+_7107799 0.616 NM_001168344
RREB1
ras responsive element binding protein 1
chr1_-_205782135 0.601 NM_173854
SLC41A1
solute carrier family 41, member 1
chr1_-_33336289 0.585 NM_001171940
NM_153756
FNDC5

fibronectin type III domain containing 5

chr4_-_40859081 0.554 NM_001166051
NM_001166052
NM_001166053
NM_001166054
APBB2



amyloid beta (A4) precursor protein-binding, family B, member 2



chr12_-_88974094 0.512 NM_000899
NM_003994
KITLG

KIT ligand

chrX_+_68048792 0.511 NM_004429
EFNB1
ephrin-B1
chr3_-_98620452 0.493 NM_080927
DCBLD2
discoidin, CUB and LCCL domain containing 2
chr3_-_190040192 0.490 NM_021101
CLDN1
claudin 1
chr4_-_120549827 0.470 NM_001083
PDE5A
phosphodiesterase 5A, cGMP-specific
chr16_-_31021716 0.462 NM_052874
STX1B
syntaxin 1B
chr1_-_33338081 0.435 NM_001171941
FNDC5
fibronectin type III domain containing 5
chr4_-_120548329 0.395 NM_033430
PDE5A
phosphodiesterase 5A, cGMP-specific
chr3_-_185216545 0.385 NM_080652
TMEM41A
transmembrane protein 41A
chr7_+_18126543 0.382 NM_001204144
HDAC9
histone deacetylase 9
chr2_-_100721792 0.368 NM_001025108
AFF3
AF4/FMR2 family, member 3
chr1_-_214724974 0.363 NM_005401
PTPN14
protein tyrosine phosphatase, non-receptor type 14
chr10_-_14372807 0.362 NM_018027
FRMD4A
FERM domain containing 4A
chr16_-_11680756 0.362 NM_001136472
NM_001136473
LITAF

lipopolysaccharide-induced TNF factor

chr7_+_18548899 0.358 NM_001204147
NM_001204148
HDAC9

histone deacetylase 9

chr1_+_27153130 0.357 NM_032283
ZDHHC18
zinc finger, DHHC-type containing 18
chr4_-_76928601 0.353 NM_002416
CXCL9
chemokine (C-X-C motif) ligand 9
chr16_-_11680146 0.338 NM_004862
LITAF
lipopolysaccharide-induced TNF factor
chr1_+_167298280 0.337 NM_001198783
POU2F1
POU class 2 homeobox 1
chr10_-_100027943 0.332 NM_032211
LOXL4
lysyl oxidase-like 4
chr8_+_22224997 0.331 NM_001135153
SLC39A14
solute carrier family 39 (zinc transporter), member 14
chr13_-_33859835 0.329 NM_178006
STARD13
StAR-related lipid transfer (START) domain containing 13
chr15_-_58358120 0.329 NM_001206897
NM_003888
NM_170696
ALDH1A2


aldehyde dehydrogenase 1 family, member A2


chr5_-_141704575 0.327 NM_001127496
NM_030964
SPRY4

sprouty homolog 4 (Drosophila)

chr13_-_33760215 0.324 NM_001243466
NM_178007
STARD13

StAR-related lipid transfer (START) domain containing 13

chr2_-_216878314 0.322 NM_018000
MREG
melanoregulin
chr2_+_30454396 0.316 NM_030915
LBH
limb bud and heart development homolog (mouse)
chr20_-_58515258 0.309 NM_006242
PPP1R3D
protein phosphatase 1, regulatory subunit 3D
chr13_-_33780142 0.308 NM_001243474
NM_052851
STARD13

StAR-related lipid transfer (START) domain containing 13

chr6_-_32806545 0.302 NM_000544
NM_018833
TAP2

transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)

chr2_-_100758970 0.301 NM_002285
AFF3
AF4/FMR2 family, member 3
chr19_-_8070468 0.301 NM_001419
ELAVL1
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)
chr16_-_84651639 0.301 NM_021149
COTL1
coactosin-like 1 (Dictyostelium)
chr15_-_58306185 0.296 NM_170697
ALDH1A2
aldehyde dehydrogenase 1 family, member A2
chr11_-_66725790 0.296 NM_000920
NM_001040716
PC

pyruvate carboxylase

chr1_+_110543548 0.295 NM_001242674
AHCYL1
adenosylhomocysteinase-like 1
chr3_-_33700932 0.294 NM_001207044
CLASP2
cytoplasmic linker associated protein 2
chr5_-_160279045 0.287 NM_025153
ATP10B
ATPase, class V, type 10B
chr14_+_37126772 0.287 NM_006194
PAX9
paired box 9
chr15_+_71433787 0.282 NM_024817
THSD4
thrombospondin, type I, domain containing 4
chr12_+_113416267 0.282 NM_001032731
NM_002535
NM_016817
OAS2


2'-5'-oligoadenylate synthetase 2, 69/71kDa


chr5_-_126366439 0.282 NM_178450
MARCH3
membrane-associated ring finger (C3HC4) 3
chr14_-_65438794 0.281 NM_198686
RAB15
RAB15, member RAS onocogene family
chr1_+_955468 0.277 NM_198576
AGRN
agrin
chr18_+_55711388 0.277 NM_001144967
NM_001243960
NM_015277
NEDD4L


neural precursor cell expressed, developmentally down-regulated 4-like


chr9_+_118916069 0.275 NM_002581
PAPPA
pregnancy-associated plasma protein A, pappalysin 1
chr7_-_139477437 0.275 NM_001113239
NM_022740
HIPK2

homeodomain interacting protein kinase 2

chr6_+_131571298 0.273 NM_004842
NM_138633
AKAP7

A kinase (PRKA) anchor protein 7

chr3_-_118753665 0.272 NM_001015887
IGSF11
immunoglobulin superfamily, member 11
chr5_-_180230889 0.272 NM_001114619
NM_001114620
MGAT1

mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase

chr14_-_73925279 0.270 NM_001005743
NM_001005744
NM_001005745
NM_003744
NUMB



numb homolog (Drosophila)



chr15_+_79724857 0.270 NM_015206
KIAA1024
KIAA1024
chr17_-_4167028 0.269 NM_016376
NM_020740
ANKFY1

ankyrin repeat and FYVE domain containing 1

chr6_+_11094265 0.267 NM_001135575
C6orf228
chromosome 6 open reading frame 228
chr18_+_55888750 0.267 NM_001144966
NEDD4L
neural precursor cell expressed, developmentally down-regulated 4-like
chr1_-_41131323 0.266 NM_014747
RIMS3
regulating synaptic membrane exocytosis 3
chr20_-_3996035 0.264 NM_007219
NM_001134337
NM_001134338
RNF24


ring finger protein 24


chrX_-_103087106 0.262 NM_016370
RAB9B
RAB9B, member RAS oncogene family
chr12_+_113229548 0.258 NM_001143854
NM_014954
RPH3A

rabphilin 3A homolog (mouse)

chr11_-_86666211 0.255 NM_012193
FZD4
frizzled family receptor 4
chr2_+_47168312 0.254 NM_020458
TTC7A
tetratricopeptide repeat domain 7A
chr18_+_55862577 0.251 NM_001144970
NEDD4L
neural precursor cell expressed, developmentally down-regulated 4-like
chr11_-_35441501 0.247 NM_001195728
NM_001252652
SLC1A2

solute carrier family 1 (glial high affinity glutamate transporter), member 2

chr12_-_129308293 0.239 NM_145648
SLC15A4
solute carrier family 15, member 4
chr17_+_46184910 0.238 NM_152244
NM_013323
SNX11

sorting nexin 11

chr14_-_104313730 0.238 NM_015316
PPP1R13B
protein phosphatase 1, regulatory subunit 13B
chr11_-_46142955 0.237 NM_001101802
NM_016621
PHF21A

PHD finger protein 21A

chr5_-_180230047 0.236 NM_002406
MGAT1
mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
chr2_+_102770401 0.236 NM_000877
IL1R1
interleukin 1 receptor, type I
chr18_+_55714457 0.234 NM_001144964
NEDD4L
neural precursor cell expressed, developmentally down-regulated 4-like
chr15_-_55562483 0.232 NM_183234
NM_004580
RAB27A

RAB27A, member RAS oncogene family

chr11_+_109964086 0.229 NM_033390
ZC3H12C
zinc finger CCCH-type containing 12C
chr5_-_146833150 0.227 NM_001387
DPYSL3
dihydropyrimidinase-like 3
chr22_+_39101806 0.227 NM_004286
GTPBP1
GTP binding protein 1
chr3_-_118864881 0.222 NM_152538
IGSF11
immunoglobulin superfamily, member 11
chr1_-_185125819 0.219 NM_030934
TRMT1L
TRM1 tRNA methyltransferase 1-like
chr9_-_32526164 0.219 NM_014314
DDX58
DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
chr5_+_31799030 0.218 NM_178140
PDZD2
PDZ domain containing 2
chr1_-_185126153 0.218 NM_001202423
TRMT1L
TRM1 tRNA methyltransferase 1-like
chr5_-_180236816 0.217 NM_001114618
MGAT1
mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
chr12_-_42538432 0.216 NM_001099650
NM_173601
GXYLT1

glucoside xylosyltransferase 1

chr15_-_55563091 0.216 NM_183236
RAB27A
RAB27A, member RAS oncogene family
chr1_+_167189948 0.214 NM_001198786
NM_002697
POU2F1

POU class 2 homeobox 1

chr1_-_36851484 0.210 NM_032017
STK40
serine/threonine kinase 40
chr5_-_180237114 0.209 NM_001114617
MGAT1
mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
chr16_-_28074776 0.208 NM_001109763
GSG1L
GSG1-like
chr9_+_115983807 0.208 NM_001859
SLC31A1
solute carrier family 31 (copper transporters), member 1
chr2_+_70142152 0.206 NM_001202513
NM_001202514
NM_002357
MXD1


MAX dimerization protein 1


chr7_+_50344255 0.205 NM_001220765
NM_001220766
NM_001220767
NM_001220768
NM_001220769
NM_001220770
NM_001220771
NM_001220772
NM_001220773
NM_001220774
NM_001220775
NM_001220776
NM_006060
IKZF1












IKAROS family zinc finger 1 (Ikaros)












chr1_-_114354906 0.204 NM_018364
RSBN1
round spermatid basic protein 1
chr9_-_133814236 0.202 NM_032843
FIBCD1
fibrinogen C domain containing 1
chr12_-_56652118 0.199 NM_173595
ANKRD52
ankyrin repeat domain 52
chr11_+_122526339 0.199 NM_032873
UBASH3B
ubiquitin associated and SH3 domain containing B
chr3_-_49967194 0.196 NM_001142501
NM_032355
MON1A

MON1 homolog A (yeast)

chr9_+_504661 0.196 NM_015158
KANK1
KN motif and ankyrin repeat domains 1
chr5_-_146889618 0.194 NM_001197294
DPYSL3
dihydropyrimidinase-like 3
chr3_-_156272909 0.194 NM_007107
SSR3
signal sequence receptor, gamma (translocon-associated protein gamma)
chr1_-_151804225 0.193 NM_005060
RORC
RAR-related orphan receptor C
chr6_+_34759743 0.192 NM_017754
UHRF1BP1
UHRF1 binding protein 1
chr5_-_131826426 0.191 NM_002198
IRF1
interferon regulatory factor 1
chr12_-_106641675 0.190 NM_006825
CKAP4
cytoskeleton-associated protein 4
chr10_+_71211215 0.190 NM_012339
TSPAN15
tetraspanin 15
chr5_-_9546157 0.190 NM_003966
SEMA5A
sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
chr1_+_101361589 0.188 NM_001144884
NM_133496
SLC30A7

solute carrier family 30 (zinc transporter), member 7

chr3_+_39509069 0.187 NM_182935
MOBP
myelin-associated oligodendrocyte basic protein
chr2_-_49381555 0.187 NM_000145
NM_181446
FSHR

follicle stimulating hormone receptor

chr6_-_7313352 0.187 NM_003144
SSR1
signal sequence receptor, alpha
chr18_+_55816546 0.187 NM_001144965
NM_001144968
NM_001144969
NM_001144971
NEDD4L



neural precursor cell expressed, developmentally down-regulated 4-like



chr19_-_6737603 0.184 NM_001080452
GPR108
G protein-coupled receptor 108
chr3_-_120461362 0.184 NM_173825
RABL3
RAB, member of RAS oncogene family-like 3
chr9_-_19786886 0.183 NM_001193288
NM_020344
SLC24A2

solute carrier family 24 (sodium/potassium/calcium exchanger), member 2

chr11_-_66675334 0.182 NM_022172
PC
pyruvate carboxylase
chr16_-_75528925 0.181 NM_021615
CHST6
carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 6
chr2_+_106361404 0.181 NM_001004722
NM_003581
NCK2

NCK adaptor protein 2

chr20_-_8000370 0.180 NM_021156
TMX4
thioredoxin-related transmembrane protein 4
chr1_-_167523016 0.180 NM_003851
CREG1
cellular repressor of E1A-stimulated genes 1
chr9_-_133814422 0.180 NM_001145106
FIBCD1
fibrinogen C domain containing 1
chr16_+_77822400 0.178 NM_020927
VAT1L
vesicle amine transport protein 1 homolog (T. californica)-like
chr17_-_33469269 0.176 NM_001014445
NM_018096
NLE1

notchless homolog 1 (Drosophila)

chr15_+_94841429 0.176 NM_001159643
NM_018349
MCTP2

multiple C2 domains, transmembrane 2

chr14_+_75894919 0.175 NM_001135048
NM_130469
JDP2

Jun dimerization protein 2

chr6_-_43543767 0.173 NM_020750
XPO5
exportin 5
chr3_+_187930720 0.173 NM_005578
LPP
LIM domain containing preferred translocation partner in lipoma
chr1_-_31712733 0.172 NM_024522
NKAIN1
Na+/K+ transporting ATPase interacting 1
chr7_-_131241321 0.172 NM_001018111
NM_005397
PODXL

podocalyxin-like

chr17_-_1532109 0.171 NM_152346
SLC43A2
solute carrier family 43, member 2
chr1_+_203444882 0.171 NM_002725
NM_201348
PRELP

proline/arginine-rich end leucine-rich repeat protein

chr16_+_70557688 0.170 NM_012426
SF3B3
splicing factor 3b, subunit 3, 130kDa
chr10_+_43572500 0.170 NM_020630
NM_020975
RET

ret proto-oncogene

chr14_+_75894508 0.170 NM_001135047
JDP2
Jun dimerization protein 2
chr15_-_55581969 0.169 NM_183235
RAB27A
RAB27A, member RAS oncogene family
chr15_-_56285732 0.167 NM_006154
NEDD4
neural precursor cell expressed, developmentally down-regulated 4
chr17_+_8214139 0.167 NM_025014
ARHGEF15
Rho guanine nucleotide exchange factor (GEF) 15
chr7_+_18535351 0.166 NM_001204145
NM_001204146
NM_014707
NM_178423
HDAC9



histone deacetylase 9



chr6_+_131456825 0.165 NM_016377
AKAP7
A kinase (PRKA) anchor protein 7
chr5_+_74807580 0.165 NM_016218
POLK
polymerase (DNA directed) kappa
chr2_-_27718098 0.165 NM_022823
FNDC4
fibronectin type III domain containing 4
chr18_+_55102777 0.163 NM_004852
ONECUT2
one cut homeobox 2
chr6_+_138483024 0.163 NM_020340
KIAA1244
KIAA1244
chr3_+_154797644 0.162 NM_007287
MME
membrane metallo-endopeptidase
chr10_+_123923104 0.161 NM_006997
NM_206860
TACC2

transforming, acidic coiled-coil containing protein 2

chr3_+_154797435 0.160 NM_000902
MME
membrane metallo-endopeptidase
chr8_+_22224758 0.159 NM_001128431
NM_001135154
NM_015359
SLC39A14


solute carrier family 39 (zinc transporter), member 14


chr1_+_119911395 0.159 NM_001005783
NM_016527
HAO2

hydroxyacid oxidase 2 (long chain)

chr4_+_140222668 0.158 NM_057175
NAA15
N(alpha)-acetyltransferase 15, NatA auxiliary subunit
chr1_+_110546569 0.158 NM_001242675
NM_001242676
AHCYL1

adenosylhomocysteinase-like 1

chr5_+_149887673 0.157 NM_001543
NDST1
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
chr12_-_6798619 0.157 NM_001039920
NM_001135734
ZNF384

zinc finger protein 384

chr14_+_75898836 0.156 NM_001135049
JDP2
Jun dimerization protein 2
chr3_+_187871473 0.155 NM_001167672
LPP
LIM domain containing preferred translocation partner in lipoma
chr12_-_16759531 0.155 NM_018640
LMO3
LIM domain only 3 (rhombotin-like 2)
chr2_-_148779172 0.155 NM_181742
ORC4
origin recognition complex, subunit 4
chr11_-_75062650 0.154 NM_004041
NM_020251
ARRB1

arrestin, beta 1

chr3_-_195808997 0.154 NM_001128148
TFRC
transferrin receptor (p90, CD71)
chr4_+_184020343 0.154 NM_024949
WWC2
WW and C2 domain containing 2
chr3_+_187943192 0.153 NM_001167671
LPP
LIM domain containing preferred translocation partner in lipoma
chr14_-_69260630 0.152 NM_001244698
NM_004926
ZFP36L1

zinc finger protein 36, C3H type-like 1

chr11_+_6624906 0.152 NM_001014794
NM_004517
ILK

integrin-linked kinase

chr12_-_6798528 0.151 NM_133476
ZNF384
zinc finger protein 384
chr2_+_106468203 0.150 NM_001004720
NCK2
NCK adaptor protein 2
chr7_+_6414089 0.150 NM_006908
NM_018890
RAC1

ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)

chr10_+_72575623 0.149 NM_003901
SGPL1
sphingosine-1-phosphate lyase 1
chr12_+_69004614 0.149 NM_001010942
NM_001251917
NM_001251918
NM_001251921
NM_001251922
NM_015646
RAP1B





RAP1B, member of RAS oncogene family





chr11_-_35441099 0.149 NM_004171
SLC1A2
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr5_-_65017874 0.148 NM_019072
SGTB
small glutamine-rich tetratricopeptide repeat (TPR)-containing, beta
chr16_-_4466961 0.148 NM_001201479
NM_001201472
NM_001201473
NM_024535
CORO7-PAM16
CORO7


CORO7-PAM16 readthrough
coronin 7


chr1_-_117210301 0.146 NM_001007237
NM_001542
IGSF3

immunoglobulin superfamily, member 3

chr9_-_117568292 0.144 NM_005118
TNFSF15
tumor necrosis factor (ligand) superfamily, member 15
chr8_+_22457098 0.144 NM_001013842
NM_001198827
NM_173686
C8orf58


chromosome 8 open reading frame 58


chr17_-_31203889 0.143 NM_015194
MYO1D
myosin ID
chr11_+_6625206 0.143 NM_001014795
ILK
integrin-linked kinase
chr20_+_35974458 0.139 NM_198291
SRC
v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)
chr17_-_71228482 0.139 NM_001098832
NM_032837
FAM104A

family with sequence similarity 104, member A

chr1_+_171283372 0.139 NM_002022
FMO4
flavin containing monooxygenase 4
chr10_+_18549583 0.138 NM_000724
CACNB2
calcium channel, voltage-dependent, beta 2 subunit
chr15_+_63481713 0.138 NM_016530
RAB8B
RAB8B, member RAS oncogene family
chr15_+_49715374 0.138 NM_002009
FGF7
fibroblast growth factor 7
chr4_+_39699663 0.138 NM_001111112
NM_001111113
NM_005339
UBE2K


ubiquitin-conjugating enzyme E2K


chr12_-_16760935 0.137 NM_001001395
NM_001243609
LMO3

LIM domain only 3 (rhombotin-like 2)

chr5_+_60933635 0.136 NM_173667
C5orf64
chromosome 5 open reading frame 64
chr8_-_27168783 0.135 NM_171982
TRIM35
tripartite motif containing 35

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
2.20 3.45e-04 GO:0007155 cell adhesion
2.20 3.45e-04 GO:0022610 biological adhesion
2.86 2.59e-03 GO:0016337 cell-cell adhesion
2.57 3.86e-03 GO:0007264 small GTPase mediated signal transduction
3.75 8.96e-03 GO:0007156 homophilic cell adhesion
1.38 1.63e-02 GO:0023052 signaling
4.63 3.55e-02 GO:0007173 epidermal growth factor receptor signaling pathway

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.21 8.47e-03 GO:0016020 membrane

Gene overrepresentation in function category:

enrichment   p-value GO term description
30.71 1.29e-02 GO:0005173 stem cell factor receptor binding
2.29 2.36e-02 GO:0019001 guanyl nucleotide binding
2.29 2.36e-02 GO:0032561 guanyl ribonucleotide binding