Motif ID: GUAAACA

Z-value: 1.429


Mature miRNA associated with seed GUAAACA:

NamemiRBase Accession
hsa-miR-30a MIMAT0000087
hsa-miR-30b MIMAT0000420
hsa-miR-30c MIMAT0000244
hsa-miR-30d MIMAT0000245
hsa-miR-30e MIMAT0000692



Activity profile for motif GUAAACA.

activity profile for motif GUAAACA


Sorted Z-values histogram for motif GUAAACA

Sorted Z-values for motif GUAAACA



Network of associatons between targets according to the STRING database.



First level regulatory network of GUAAACA

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr8_-_22549901 3.002 NM_001199880
EGR3
early growth response 3
chr8_-_22550057 2.967 NM_001199881
EGR3
early growth response 3
chr8_-_22550708 2.950 NM_004430
EGR3
early growth response 3
chr20_+_58515408 2.727 NM_001190827
NM_022106
C20orf177

chromosome 20 open reading frame 177

chr20_+_58508818 2.713 NM_001190826
C20orf177
chromosome 20 open reading frame 177
chr12_-_42877785 2.705 NM_001144882
NM_001144883
PRICKLE1

prickle homolog 1 (Drosophila)

chr12_-_42983412 2.699 NM_153026
PRICKLE1
prickle homolog 1 (Drosophila)
chr13_+_58205788 2.630 NM_001040429
PCDH17
protocadherin 17
chr12_-_42877413 2.629 NM_001144881
PRICKLE1
prickle homolog 1 (Drosophila)
chr10_-_131762017 2.534 NM_001005463
EBF3
early B-cell factor 3
chr20_-_45985411 2.288 NM_012408
NM_183047
NM_183048
ZMYND8


zinc finger, MYND-type containing 8


chr7_-_27224762 2.258 NM_005523
HOXA11
homeobox A11
chr4_-_149363498 2.079 NM_000901
NM_001166104
NR3C2

nuclear receptor subfamily 3, group C, member 2

chr12_-_106533810 2.078 NM_014840
NUAK1
NUAK family, SNF1-like kinase, 1
chr11_-_27681195 2.042 NM_001143816
NM_170735
BDNF

brain-derived neurotrophic factor

chr11_-_27721975 1.983 NM_001143813
NM_001143814
NM_001709
BDNF


brain-derived neurotrophic factor


chr5_-_72861376 1.932 NM_023039
ANKRA2
ankyrin repeat, family A (RFXANK-like), 2
chr11_-_27722599 1.838 NM_001143808
NM_001143809
NM_001143810
NM_001143811
BDNF



brain-derived neurotrophic factor



chr11_-_27722446 1.837 NM_001143812
BDNF
brain-derived neurotrophic factor
chr11_-_27743604 1.747 NM_170731
BDNF
brain-derived neurotrophic factor
chr11_-_27723061 1.732 NM_170733
BDNF
brain-derived neurotrophic factor
chr11_-_27721179 1.729 NM_170734
BDNF
brain-derived neurotrophic factor
chr10_+_97889467 1.703 NM_014803
ZNF518A
zinc finger protein 518A
chr7_-_112579726 1.690 NM_152556
C7orf60
chromosome 7 open reading frame 60
chr11_-_27742224 1.663 NM_001143805
NM_001143806
NM_170732
BDNF


brain-derived neurotrophic factor


chr11_-_27741192 1.657 NM_001143807
BDNF
brain-derived neurotrophic factor
chr6_+_11538486 1.490 NM_001100829
TMEM170B
transmembrane protein 170B
chr15_-_52970808 1.477 NM_019600
FAM214A
family with sequence similarity 214, member A
chr4_+_175204827 1.456 NM_001040157
CEP44
centrosomal protein 44kDa
chr1_-_197169635 1.388 NM_194314
ZBTB41
zinc finger and BTB domain containing 41
chr1_+_116184573 1.353 NM_001172411
NM_138959
VANGL1

vang-like 1 (van gogh, Drosophila)

chr8_-_82754427 1.335 NM_022133
NM_152836
NM_152837
SNX16


sorting nexin 16


chr15_-_56035176 1.331 NM_173814
PRTG
protogenin
chr7_+_8008416 1.320 NM_138426
GLCCI1
glucocorticoid induced transcript 1
chr1_+_116185249 1.319 NM_001172412
VANGL1
vang-like 1 (van gogh, Drosophila)
chr3_-_129612371 1.313 NM_001128224
TMCC1
transmembrane and coiled-coil domain family 1
chr14_-_74253876 1.311 NM_001043318
C14orf43
chromosome 14 open reading frame 43
chr7_-_28998028 1.304 NM_014817
TRIL
TLR4 interactor with leucine-rich repeats
chr14_-_74226890 1.296 NM_194278
C14orf43
chromosome 14 open reading frame 43
chr2_-_217236666 1.275 NM_020814
MARCH4
membrane-associated ring finger (C3HC4) 4
chr8_-_103667882 1.247 NM_005655
KLF10
Kruppel-like factor 10
chr16_+_68119211 1.237 NM_004555
NM_173163
NM_173165
NFATC3


nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3


chr6_-_119031230 1.218 NM_001178035
CEP85L
centrosomal protein 85kDa-like
chr2_-_208890207 1.214 NM_001080475
PLEKHM3
pleckstrin homology domain containing, family M, member 3
chr2_-_157189040 1.196 NM_006186
NR4A2
nuclear receptor subfamily 4, group A, member 2
chr2_-_219432955 1.193 NM_020935
USP37
ubiquitin specific peptidase 37
chr3_-_129599220 1.179 NM_001017395
TMCC1
transmembrane and coiled-coil domain family 1
chr14_+_58765209 1.172 NM_002892
NM_023000
NM_023001
ARID4A


AT rich interactive domain 4A (RBP1-like)


chr12_-_42538432 1.152 NM_001099650
NM_173601
GXYLT1

glucoside xylosyltransferase 1

chr4_-_18023358 1.150 NM_001166139
NM_153686
LCORL

ligand dependent nuclear receptor corepressor-like

chr4_-_89744154 1.136 NM_001015045
FAM13A
family with sequence similarity 13, member A
chr18_+_60190657 1.133 NM_017742
ZCCHC2
zinc finger, CCHC domain containing 2
chr16_+_50186809 1.132 NM_001040284
NM_001040285
PAPD5

PAP associated domain containing 5

chr17_-_60005309 1.110 NM_020748
INTS2
integrator complex subunit 2
chr5_+_53813494 1.097 NM_001145427
NM_001102575
NM_052870
SNX18


sorting nexin 18


chr2_+_32288579 1.093 NM_014946
NM_199436
SPAST

spastin

chr8_-_103666018 1.092 NM_001032282
KLF10
Kruppel-like factor 10
chr14_+_100259445 1.079 NM_001008707
NM_004434
EML1

echinoderm microtubule associated protein like 1

chr13_-_113242467 1.045 NM_006322
TUBGCP3
tubulin, gamma complex associated protein 3
chr16_+_53088791 1.009 NM_025134
CHD9
chromodomain helicase DNA binding protein 9
chr18_-_29264394 0.999 NM_004775
B4GALT6
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6
chr8_-_95961543 0.993 NM_001135733
NM_033285
TP53INP1

tumor protein p53 inducible nuclear protein 1

chr2_-_64371444 0.983 NM_020651
PELI1
pellino homolog 1 (Drosophila)
chr15_+_41221530 0.939 NM_019074
DLL4
delta-like 4 (Drosophila)
chrX_-_33229428 0.937 NM_004006
DMD
dystrophin
chr16_+_66914380 0.927 NM_020786
PDP2
pyruvate dehyrogenase phosphatase catalytic subunit 2
chr10_+_70320044 0.918 NM_030625
TET1
tet methylcytosine dioxygenase 1
chr7_-_99756275 0.898 NM_018275
C7orf43
chromosome 7 open reading frame 43
chr20_-_31071187 0.897 NM_080616
C20orf112
chromosome 20 open reading frame 112
chr2_+_233561997 0.887 NM_001103146
NM_001103147
NM_001103148
NM_015575
GIGYF2



GRB10 interacting GYF protein 2



chr5_+_52284903 0.879 NM_002203
ITGA2
integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
chr3_-_18466759 0.873 NM_001195470
NM_002971
SATB1

SATB homeobox 1

chr10_-_81205091 0.869 NM_153367
ZCCHC24
zinc finger, CCHC domain containing 24
chr7_+_12250818 0.864 NM_001134232
NM_018374
TMEM106B

transmembrane protein 106B

chr2_-_201828180 0.860 NM_006190
ORC2
origin recognition complex, subunit 2
chr11_-_67888857 0.854 NM_001277
NM_212469
CHKA

choline kinase alpha

chr8_+_92082423 0.847 NM_016023
OTUD6B
OTU domain containing 6B
chr20_+_48599511 0.845 NM_005985
SNAI1
snail homolog 1 (Drosophila)
chr16_+_24740945 0.841 NM_014494
TNRC6A
trinucleotide repeat containing 6A
chrX_-_114468604 0.839 NM_001243963
NM_020871
LRCH2

leucine-rich repeats and calponin homology (CH) domain containing 2

chrX_-_32173585 0.814 NM_004013
NM_004020
NM_004021
NM_004022
NM_004023
DMD




dystrophin




chr1_+_151584514 0.809 NM_030918
SNX27
sorting nexin family member 27
chr5_+_60628085 0.806 NM_020928
ZSWIM6
zinc finger, SWIM-type containing 6
chr6_-_79787939 0.796 NM_017934
PHIP
pleckstrin homology domain interacting protein
chrX_-_31526414 0.795 NM_004014
DMD
dystrophin
chr3_-_18480203 0.793 NM_001131010
SATB1
SATB homeobox 1
chr10_-_74856656 0.789 NM_000917
NM_001017962
NM_001142595
NM_001142596
P4HA1



prolyl 4-hydroxylase, alpha polypeptide I



chr12_-_80329234 0.786 NM_001143885
NM_001244990
PPP1R12A

protein phosphatase 1, regulatory subunit 12A

chr1_+_244216506 0.781 NM_006352
ZNF238
zinc finger protein 238
chr18_-_22932109 0.769 NM_015461
ZNF521
zinc finger protein 521
chr6_+_121756744 0.769 NM_000165
GJA1
gap junction protein, alpha 1, 43kDa
chr9_-_27573444 0.769 NM_018325
C9orf72
chromosome 9 open reading frame 72
chr5_+_149151502 0.761 NM_001172699
PPARGC1B
peroxisome proliferator-activated receptor gamma, coactivator 1 beta
chr4_-_170192193 0.759 NM_020870
SH3RF1
SH3 domain containing ring finger 1
chr1_+_244214552 0.757 NM_205768
ZNF238
zinc finger protein 238
chrX_-_33146543 0.747 NM_004010
NM_004009
DMD

dystrophin

chr10_+_92980322 0.735 NM_032373
PCGF5
polycomb group ring finger 5
chr6_+_107811272 0.734 NM_018013
SOBP
sine oculis binding protein homolog (Drosophila)
chr15_+_47476225 0.732 NM_001198999
SEMA6D
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
chrX_-_32430370 0.731 NM_004011
NM_004012
DMD

dystrophin

chr11_-_67141008 0.726 NM_013246
CLCF1
cardiotrophin-like cytokine factor 1
chr1_+_53192021 0.725 NM_024646
ZYG11B
zyg-11 homolog B (C. elegans)
chr15_+_96876568 0.724 NM_001145157
NR2F2
nuclear receptor subfamily 2, group F, member 2
chr11_-_67141647 0.724 NM_001166212
CLCF1
cardiotrophin-like cytokine factor 1
chr12_-_80307690 0.720 NM_001143886
PPP1R12A
protein phosphatase 1, regulatory subunit 12A
chr1_-_45672225 0.719 NM_020883
ZSWIM5
zinc finger, SWIM-type containing 5
chr3_+_142838596 0.717 NM_004267
CHST2
carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2
chrX_-_33357725 0.714 NM_000109
DMD
dystrophin
chr3_-_105587710 0.710 NM_170662
CBLB
Cas-Br-M (murine) ecotropic retroviral transforming sequence b
chr1_+_173684061 0.706 NM_014458
KLHL20
kelch-like 20 (Drosophila)
chr12_-_53893195 0.703 NM_001193511
NM_006301
MAP3K12

mitogen-activated protein kinase kinase kinase 12

chr12_+_111843743 0.700 NM_005475
SH2B3
SH2B adaptor protein 3
chr9_-_139440237 0.693 NM_017617
NOTCH1
notch 1
chr1_+_222791151 0.693 NM_198551
MIA3
melanoma inhibitory activity family, member 3
chr4_+_26862312 0.690 NM_001169117
NM_001169118
NM_020860
STIM2


stromal interaction molecule 2


chr4_-_166034003 0.688 NM_001100389
TMEM192
transmembrane protein 192
chr5_-_100238870 0.687 NM_175052
NM_005668
ST8SIA4

ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4

chrX_-_31284946 0.682 NM_004015
NM_004016
NM_004017
NM_004018
NM_004019
DMD




dystrophin




chr15_-_72490109 0.682 NM_001012642
GRAMD2
GRAM domain containing 2
chr8_+_76452202 0.682 NM_004133
HNF4G
hepatocyte nuclear factor 4, gamma
chr2_-_100106478 0.675 NM_001037872
NM_016316
REV1

REV1 homolog (S. cerevisiae)

chr16_-_30022300 0.674 NM_003586
DOC2A
double C2-like domains, alpha
chr12_-_80328926 0.665 NM_002480
PPP1R12A
protein phosphatase 1, regulatory subunit 12A
chr12_-_90049818 0.663 NM_001001323
NM_001682
ATP2B1

ATPase, Ca++ transporting, plasma membrane 1

chr19_+_13261272 0.663 NM_004907
IER2
immediate early response 2
chr2_-_99552677 0.659 NM_207362
C2orf55
chromosome 2 open reading frame 55
chr9_-_125590809 0.656 NM_005388
PDCL
phosducin-like
chr6_+_158957467 0.654 NM_020823
TMEM181
transmembrane protein 181
chr22_+_40440664 0.654 NM_001024843
TNRC6B
trinucleotide repeat containing 6B
chr17_-_71228482 0.653 NM_001098832
NM_032837
FAM104A

family with sequence similarity 104, member A

chr10_-_23003443 0.649 NM_005028
PIP4K2A
phosphatidylinositol-5-phosphate 4-kinase, type II, alpha
chr14_+_96846021 0.648 NM_016472
C14orf129
chromosome 14 open reading frame 129
chr3_-_195163575 0.643 NM_012287
ACAP2
ArfGAP with coiled-coil, ankyrin repeat and PH domains 2
chr2_+_86668270 0.639 NM_018433
KDM3A
lysine (K)-specific demethylase 3A
chr22_-_22863504 0.637 NM_080764
ZNF280B
zinc finger protein 280B
chr9_-_14693459 0.635 NM_178566
ZDHHC21
zinc finger, DHHC-type containing 21
chr17_-_65241305 0.632 NM_014877
HELZ
helicase with zinc finger
chr2_-_61245363 0.632 NM_144709
PUS10
pseudouridylate synthase 10
chr5_+_149109814 0.630 NM_001172698
NM_133263
PPARGC1B

peroxisome proliferator-activated receptor gamma, coactivator 1 beta

chrX_-_72299224 0.627 NM_001012977
PABPC1L2A
PABPC1L2B
poly(A) binding protein, cytoplasmic 1-like 2A
poly(A) binding protein, cytoplasmic 1-like 2B
chr17_-_76356153 0.627 NM_003955
SOCS3
suppressor of cytokine signaling 3
chr1_+_204042191 0.626 NM_005686
SOX13
SRY (sex determining region Y)-box 13
chr17_+_76000248 0.624 NM_001142640
NM_018996
TNRC6C

trinucleotide repeat containing 6C

chr15_+_96875793 0.622 NM_001145156
NR2F2
nuclear receptor subfamily 2, group F, member 2
chr1_+_64936475 0.617 NM_020925
CACHD1
cache domain containing 1
chr5_-_141392537 0.617 NM_005471
GNPDA1
glucosamine-6-phosphate deaminase 1
chr4_+_174089889 0.611 NM_017423
GALNT7
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 7 (GalNAc-T7)
chr15_+_51200864 0.610 NM_001252127
NM_007347
AP4E1

adaptor-related protein complex 4, epsilon 1 subunit

chr1_-_236030219 0.608 NM_000081
LYST
lysosomal trafficking regulator
chr14_+_53196852 0.607 NM_001130701
NM_145251
STYX

serine/threonine/tyrosine interacting protein

chr15_-_43662107 0.596 NM_152455
ZSCAN29
zinc finger and SCAN domain containing 29
chr7_+_21467572 0.596 NM_003112
SP4
Sp4 transcription factor
chr6_-_53409897 0.595 NM_001197115
NM_001498
GCLC

glutamate-cysteine ligase, catalytic subunit

chr5_+_89770680 0.594 NM_006467
POLR3G
polymerase (RNA) III (DNA directed) polypeptide G (32kD)
chr3_+_107241782 0.592 NM_001142568
NM_020235
BBX

bobby sox homolog (Drosophila)

chr17_-_61920328 0.584 NM_001098426
SMARCD2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2
chr8_+_124780742 0.584 NM_144963
FAM91A1
family with sequence similarity 91, member A1
chr17_-_2304217 0.583 NM_020310
MNT
MAX binding protein
chr6_-_118973019 0.582 NM_001042475
NM_206921
CEP85L

centrosomal protein 85kDa-like

chr2_-_86564632 0.577 NM_001164731
NM_001164732
NM_022912
REEP1


receptor accessory protein 1


chr6_+_15246299 0.575 NM_004973
JARID2
jumonji, AT rich interactive domain 2
chr17_-_37557851 0.573 NM_001184906
NM_032875
FBXL20

F-box and leucine-rich repeat protein 20

chr3_-_50605062 0.571 NM_001171740
NM_001171743
NM_016210
C3orf18


chromosome 3 open reading frame 18


chr8_+_26240522 0.569 NM_004331
BNIP3L
BCL2/adenovirus E1B 19kDa interacting protein 3-like
chr13_-_73301726 0.568 NM_001071775
MZT1
mitotic spindle organizing protein 1
chr15_+_96869156 0.567 NM_001145155
NR2F2
nuclear receptor subfamily 2, group F, member 2
chr9_+_131799212 0.567 NM_032809
FAM73B
family with sequence similarity 73, member B
chr19_+_925984 0.566 NM_005224
ARID3A
AT rich interactive domain 3A (BRIGHT-like)
chr17_+_4981721 0.564 NM_153018
ZFP3
zinc finger protein 3 homolog (mouse)
chr1_-_44497132 0.564 NM_001024845
SLC6A9
solute carrier family 6 (neurotransmitter transporter, glycine), member 9
chr1_+_65210724 0.560 NM_018211
RAVER2
ribonucleoprotein, PTB-binding 2
chr5_+_176560056 0.556 NM_172349
NSD1
nuclear receptor binding SET domain protein 1
chr3_-_125094003 0.554 NM_021964
ZNF148
zinc finger protein 148
chr6_-_99963245 0.554 NM_001080481
USP45
ubiquitin specific peptidase 45
chr9_+_4679557 0.552 NM_017913
CDC37L1
cell division cycle 37 homolog (S. cerevisiae)-like 1
chrX_+_107069081 0.551 NM_012216
NM_052817
MID2

midline 2

chr12_-_31743822 0.551 NM_144973
DENND5B
DENN/MADD domain containing 5B
chr7_+_26331493 0.550 NM_001199835
NM_013322
SNX10

sorting nexin 10

chr1_-_179112178 0.550 NM_001136000
NM_001168239
NM_005158
ABL2


v-abl Abelson murine leukemia viral oncogene homolog 2


chr12_+_69633316 0.546 NM_007007
CPSF6
cleavage and polyadenylation specific factor 6, 68kDa
chr12_-_12419702 0.545 NM_002336
LRP6
low density lipoprotein receptor-related protein 6
chr15_-_56535475 0.542 NM_022841
RFX7
regulatory factor X, 7
chr12_-_39299335 0.541 NM_153634
CPNE8
copine VIII
chr2_-_70475563 0.540 NM_022037
NM_022173
TIA1

TIA1 cytotoxic granule-associated RNA binding protein

chrX_+_72782961 0.539 NM_001039840
CHIC1
cysteine-rich hydrophobic domain 1
chr5_+_174905513 0.538 NM_022754
SFXN1
sideroflexin 1
chr2_-_169103886 0.538 NM_013233
STK39
serine threonine kinase 39
chr9_-_111882209 0.537 NM_032012
C9orf5
chromosome 9 open reading frame 5
chr15_-_65579017 0.536 NM_017851
PARP16
poly (ADP-ribose) polymerase family, member 16
chr19_-_6110561 0.533 NM_000635
NM_134433
RFX2

regulatory factor X, 2 (influences HLA class II expression)

chr5_+_86564044 0.530 NM_002890
RASA1
RAS p21 protein activator (GTPase activating protein) 1
chr2_-_38604430 0.530 NM_001135673
NM_022374
ATL2

atlastin GTPase 2

chr9_-_138987096 0.526 NM_144653
NACC2
NACC family member 2, BEN and BTB (POZ) domain containing
chr20_+_306205 0.525 NM_006943
SOX12
SRY (sex determining region Y)-box 12
chr12_+_122516555 0.525 NM_014938
MLXIP
MLX interacting protein
chr10_-_94333847 0.517 NM_004969
IDE
insulin-degrading enzyme
chr4_-_85887543 0.517 NM_014991
WDFY3
WD repeat and FYVE domain containing 3
chrX_+_48916515 0.515 NM_001163322
NM_033626
NM_001163321
NM_001163323
CCDC120



coiled-coil domain containing 120



chr9_+_131843378 0.514 NM_001135917
NM_020438
DOLPP1

dolichyl pyrophosphate phosphatase 1

chr10_+_74033676 0.513 NM_019058
DDIT4
DNA-damage-inducible transcript 4

Gene Ontology Analysis

Nothing significant found in process category.

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.15 2.91e-07 GO:0005622 intracellular
1.14 1.57e-06 GO:0044424 intracellular part
1.15 3.39e-04 GO:0043229 intracellular organelle
1.15 4.51e-04 GO:0043226 organelle
1.06 3.11e-03 GO:0044464 cell part
1.06 3.18e-03 GO:0005623 cell
1.91 9.26e-03 GO:0000139 Golgi membrane
1.74 3.82e-02 GO:0044431 Golgi apparatus part
1.42 3.91e-02 GO:0012505 endomembrane system
1.13 4.73e-02 GO:0043231 intracellular membrane-bounded organelle

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.47 5.74e-04 GO:0008270 zinc ion binding
1.10 4.48e-03 GO:0005488 binding
1.39 5.57e-03 GO:0046914 transition metal ion binding
1.28 7.24e-03 GO:0046872 metal ion binding
1.27 8.11e-03 GO:0043169 cation binding
1.27 9.67e-03 GO:0043167 ion binding
2.89 2.26e-02 GO:0035091 phosphatidylinositol binding
1.16 2.78e-02 GO:0005515 protein binding