Motif ID: GUAACAG

Z-value: 0.456


Mature miRNA associated with seed GUAACAG:

NamemiRBase Accession
hsa-miR-194 MIMAT0000460



Activity profile for motif GUAACAG.

activity profile for motif GUAACAG


Sorted Z-values histogram for motif GUAACAG

Sorted Z-values for motif GUAACAG



Network of associatons between targets according to the STRING database.



First level regulatory network of GUAACAG

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr3_-_18466759 1.259 NM_001195470
NM_002971
SATB1

SATB homeobox 1

chr3_-_18480203 1.229 NM_001131010
SATB1
SATB homeobox 1
chr5_-_88179278 0.687 NM_001193350
NM_002397
MEF2C

myocyte enhancer factor 2C

chr5_-_88199868 0.651 NM_001131005
NM_001193347
MEF2C

myocyte enhancer factor 2C

chr2_-_190445521 0.609 NM_014585
SLC40A1
solute carrier family 40 (iron-regulated transporter), member 1
chr9_-_124990706 0.595 NM_001242333
LHX6
LIM homeobox 6
chr3_+_39851028 0.594 NM_015460
MYRIP
myosin VIIA and Rab interacting protein
chr1_+_82266081 0.589 NM_012302
LPHN2
latrophilin 2
chr3_-_64211111 0.584 NM_198859
PRICKLE2
prickle homolog 2 (Drosophila)
chr9_-_124984018 0.582 NM_001242335
LHX6
LIM homeobox 6
chr2_+_203499819 0.570 NM_173511
FAM117B
family with sequence similarity 117, member B
chr13_-_72441312 0.540 NM_004392
NM_080759
NM_080760
DACH1


dachshund homolog 1 (Drosophila)


chr9_-_124990949 0.521 NM_014368
NM_199160
LHX6

LIM homeobox 6

chr5_-_88119604 0.509 NM_001193348
NM_001193349
MEF2C

myocyte enhancer factor 2C

chr14_-_74226890 0.505 NM_194278
C14orf43
chromosome 14 open reading frame 43
chrX_-_119709618 0.498 NM_003588
CUL4B
cullin 4B
chr4_+_87928083 0.474 NM_005935
AFF1
AF4/FMR2 family, member 1
chr14_-_74253876 0.436 NM_001043318
C14orf43
chromosome 14 open reading frame 43
chr3_+_37903643 0.433 NM_001008392
NM_005808
CTDSPL

CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like

chr4_+_41362750 0.433 NM_001112717
NM_001112718
NM_014988
LIMCH1


LIM and calponin homology domains 1


chr1_-_211752052 0.429 NM_021194
SLC30A1
solute carrier family 30 (zinc transporter), member 1
chr4_+_41614911 0.414 NM_001112719
NM_001112720
LIMCH1

LIM and calponin homology domains 1

chr8_-_28243941 0.414 NM_018660
ZNF395
zinc finger protein 395
chr9_-_124989755 0.414 NM_001242334
LHX6
LIM homeobox 6
chrX_-_119694719 0.402 NM_001079872
CUL4B
cullin 4B
chr12_-_31743822 0.384 NM_144973
DENND5B
DENN/MADD domain containing 5B
chr12_+_27677044 0.366 NM_001198915
NM_001198916
NM_003622
NM_177444
PPFIBP1



PTPRF interacting protein, binding protein 1 (liprin beta 1)



chr13_-_45992474 0.353 NM_001010875
SLC25A30
solute carrier family 25, member 30
chr2_-_99347588 0.352 NM_012214
MGAT4A
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
chr14_+_85996454 0.333 NM_013231
FLRT2
fibronectin leucine rich transmembrane protein 2
chr15_-_56035176 0.332 NM_173814
PRTG
protogenin
chr4_+_87856152 0.323 NM_001166693
AFF1
AF4/FMR2 family, member 1
chr6_-_111804413 0.320 NM_002912
REV3L
REV3-like, catalytic subunit of DNA polymerase zeta (yeast)
chr3_+_32280154 0.305 NM_178868
CMTM8
CKLF-like MARVEL transmembrane domain containing 8
chr4_+_86396251 0.305 NM_001025616
ARHGAP24
Rho GTPase activating protein 24
chr12_+_93963597 0.303 NM_003877
SOCS2
suppressor of cytokine signaling 2
chr15_+_96876568 0.299 NM_001145157
NR2F2
nuclear receptor subfamily 2, group F, member 2
chr5_+_176560056 0.289 NM_172349
NSD1
nuclear receptor binding SET domain protein 1
chr4_+_86851425 0.267 NM_031305
ARHGAP24
Rho GTPase activating protein 24
chr12_-_29534089 0.266 NM_016570
ERGIC2
ERGIC and golgi 2
chr10_-_65225605 0.263 NM_032776
JMJD1C
jumonji domain containing 1C
chr1_+_222791151 0.260 NM_198551
MIA3
melanoma inhibitory activity family, member 3
chr5_+_176560627 0.260 NM_022455
NSD1
nuclear receptor binding SET domain protein 1
chr15_+_96875793 0.259 NM_001145156
NR2F2
nuclear receptor subfamily 2, group F, member 2
chr12_-_76425375 0.259 NM_007350
PHLDA1
pleckstrin homology-like domain, family A, member 1
chr11_-_17410205 0.257 NM_000525
KCNJ11
potassium inwardly-rectifying channel, subfamily J, member 11
chr4_+_86699846 0.255 NM_001042669
ARHGAP24
Rho GTPase activating protein 24
chr10_-_65028825 0.252 NM_004241
JMJD1C
jumonji domain containing 1C
chr13_-_41240607 0.252 NM_002015
FOXO1
forkhead box O1
chr11_-_17410863 0.248 NM_001166290
KCNJ11
potassium inwardly-rectifying channel, subfamily J, member 11
chr15_+_96869156 0.241 NM_001145155
NR2F2
nuclear receptor subfamily 2, group F, member 2
chr11_+_61520000 0.241 NM_001127392
C11orf9
chromosome 11 open reading frame 9
chr10_-_75634219 0.239 NM_001204492
NM_001222
NM_172169
NM_172170
NM_172171
NM_172173
CAMK2G





calcium/calmodulin-dependent protein kinase II gamma





chr12_-_25055966 0.234 NM_001178093
BCAT1
branched chain amino-acid transaminase 1, cytosolic
chr9_-_8733893 0.228 NM_001040712
NM_001171025
NM_130391
NM_130392
NM_130393
PTPRD




protein tyrosine phosphatase, receptor type, D




chr12_-_25055228 0.221 NM_001178094
BCAT1
branched chain amino-acid transaminase 1, cytosolic
chr9_-_10612722 0.220 NM_002839
PTPRD
protein tyrosine phosphatase, receptor type, D
chr2_+_238600780 0.219 NM_001137551
NM_001137552
NM_001137553
NM_004735
LRRFIP1



leucine rich repeat (in FLII) interacting protein 1



chr12_-_25102281 0.215 NM_001178091
NM_001178092
NM_005504
BCAT1


branched chain amino-acid transaminase 1, cytosolic


chr2_-_158731622 0.212 NM_001105
ACVR1
activin A receptor, type I
chr14_-_54955714 0.210 NM_004124
GMFB
glia maturation factor, beta
chr17_+_61699786 0.209 NM_002401
NM_203351
MAP3K3

mitogen-activated protein kinase kinase kinase 3

chr4_+_88928797 0.197 NM_000297
PKD2
polycystic kidney disease 2 (autosomal dominant)
chr16_+_69599868 0.191 NM_001113178
NM_006599
NM_138713
NM_138714
NM_173214
NM_173215
NFAT5





nuclear factor of activated T-cells 5, tonicity-responsive





chr5_+_176875325 0.187 NM_001174102
PRR7
proline rich 7 (synaptic)
chr15_+_96873845 0.185 NM_021005
NR2F2
nuclear receptor subfamily 2, group F, member 2
chr2_-_158732341 0.181 NM_001111067
ACVR1
activin A receptor, type I
chr17_+_48796919 0.178 NM_006107
NM_016424
LUC7L3

LUC7-like 3 (S. cerevisiae)

chr16_+_53088791 0.177 NM_025134
CHD9
chromodomain helicase DNA binding protein 9
chr12_+_46123495 0.173 NM_152641
ARID2
AT rich interactive domain 2 (ARID, RFX-like)
chr11_-_86666211 0.169 NM_012193
FZD4
frizzled family receptor 4
chr9_-_138987096 0.165 NM_144653
NACC2
NACC family member 2, BEN and BTB (POZ) domain containing
chr14_+_58765209 0.164 NM_002892
NM_023000
NM_023001
ARID4A


AT rich interactive domain 4A (RBP1-like)


chr6_+_107811272 0.163 NM_018013
SOBP
sine oculis binding protein homolog (Drosophila)
chrX_-_135338640 0.161 NM_001173516
MAP7D3
MAP7 domain containing 3
chr9_+_131451470 0.158 NM_003011
SET
SET nuclear oncogene
chr9_+_131445933 0.155 NM_001122821
SET
SET nuclear oncogene
chr15_-_59225800 0.153 NM_001013843
NM_024755
SLTM

SAFB-like, transcription modulator

chr4_+_1795004 0.152 NM_000142
NM_001163213
NM_022965
FGFR3


fibroblast growth factor receptor 3


chr12_-_118406027 0.148 NM_173598
KSR2
kinase suppressor of ras 2
chr7_-_42276617 0.147 NM_000168
GLI3
GLI family zinc finger 3
chr20_-_40246991 0.144 NM_032221
CHD6
chromodomain helicase DNA binding protein 6
chr8_+_38034066 0.142 NM_001204878
NM_004874
BAG4

BCL2-associated athanogene 4

chr10_-_33623771 0.141 NM_001024628
NM_001024629
NM_001244972
NM_001244973
NM_003873
NRP1




neuropilin 1




chr3_-_149688638 0.139 NM_002628
NM_053024
PFN2

profilin 2

chr17_+_38474472 0.139 NM_001145301
NM_001145302
RARA

retinoic acid receptor, alpha

chr3_-_126076057 0.137 NM_014079
KLF15
Kruppel-like factor 15
chr12_-_120806893 0.137 NM_002442
MSI1
musashi homolog 1 (Drosophila)
chr14_+_74551655 0.136 NM_001024674
LIN52
lin-52 homolog (C. elegans)
chr7_+_77325729 0.136 NM_198467
RSBN1L
round spermatid basic protein 1-like
chr16_+_47495166 0.135 NM_000293
NM_001031835
PHKB

phosphorylase kinase, beta

chr17_+_66508525 0.134 NM_002734
NM_212472
PRKAR1A

protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1)

chr11_+_61522860 0.134 NM_013279
C11orf9
chromosome 11 open reading frame 9
chr17_+_66508098 0.133 NM_212471
PRKAR1A
protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1)
chr10_-_64578926 0.133 NM_001136178
EGR2
early growth response 2
chr6_+_158957467 0.133 NM_020823
TMEM181
transmembrane protein 181
chr1_-_225840660 0.133 NM_001008493
NM_018212
ENAH

enabled homolog (Drosophila)

chr8_-_103424897 0.131 NM_015902
UBR5
ubiquitin protein ligase E3 component n-recognin 5
chr3_+_32726659 0.131 NM_015442
CNOT10
CCR4-NOT transcription complex, subunit 10
chr7_-_152133071 0.129 NM_170606
MLL3
myeloid/lymphoid or mixed-lineage leukemia 3
chr18_+_56530060 0.129 NM_018181
ZNF532
zinc finger protein 532
chr10_-_64576123 0.128 NM_000399
NM_001136177
NM_001136179
EGR2


early growth response 2


chr9_-_123555654 0.124 NM_012164
FBXW2
F-box and WD repeat domain containing 2
chr1_-_212965104 0.122 NM_001042549
NM_015471
NSL1

NSL1, MIND kinetochore complex component, homolog (S. cerevisiae)

chr10_-_32217762 0.122 NM_018287
ARHGAP12
Rho GTPase activating protein 12
chr18_+_6834431 0.121 NM_001010000
ARHGAP28
Rho GTPase activating protein 28
chr12_+_56915587 0.120 NM_002898
RBMS2
RNA binding motif, single stranded interacting protein 2
chrX_+_119737743 0.120 NM_014060
MCTS1
malignant T cell amplified sequence 1
chr20_-_56285576 0.120 NM_199169
NM_199170
PMEPA1

prostate transmembrane protein, androgen induced 1

chr10_+_97889467 0.119 NM_014803
ZNF518A
zinc finger protein 518A
chr17_+_38465422 0.117 NM_000964
RARA
retinoic acid receptor, alpha
chr4_-_5711274 0.116 NM_001166136
EVC2
Ellis van Creveld syndrome 2
chrX_-_33229428 0.115 NM_004006
DMD
dystrophin
chr17_-_36956145 0.115 NM_003559
PIP4K2B
phosphatidylinositol-5-phosphate 4-kinase, type II, beta
chrX_+_119738542 0.115 NM_001137554
MCTS1
malignant T cell amplified sequence 1
chr9_-_14693459 0.113 NM_178566
ZDHHC21
zinc finger, DHHC-type containing 21
chr2_-_122406994 0.112 NM_001142273
NM_001142274
NM_001207051
NM_015282
CLASP1



cytoplasmic linker associated protein 1



chr14_+_39736277 0.111 NM_001247989
NM_001247990
NM_005930
NM_203355
CTAGE5



CTAGE family, member 5



chr17_-_58603492 0.109 NM_006380
APPBP2
amyloid beta precursor protein (cytoplasmic tail) binding protein 2
chr2_+_85198176 0.108 NM_020122
KCMF1
potassium channel modulatory factor 1
chr15_-_34629044 0.106 NM_001042497
NM_133647
SLC12A6

solute carrier family 12 (potassium/chloride transporters), member 6

chr15_+_77713229 0.101 NM_018200
HMG20A
high mobility group 20A
chr17_-_65241305 0.099 NM_014877
HELZ
helicase with zinc finger
chr13_+_28712379 0.096 NM_175854
PAN3
PAN3 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)
chrX_-_32173585 0.095 NM_004013
NM_004020
NM_004021
NM_004022
NM_004023
DMD




dystrophin




chr18_+_19321544 0.095 NM_020774
MIB1
mindbomb homolog 1 (Drosophila)
chr18_-_25757351 0.094 NM_001792
CDH2
cadherin 2, type 1, N-cadherin (neuronal)
chr14_+_39734475 0.093 NM_203354
CTAGE5
CTAGE family, member 5
chr20_+_36661849 0.093 NM_021215
RPRD1B
regulation of nuclear pre-mRNA domain containing 1B
chr18_-_29523087 0.092 NM_014939
TRAPPC8
trafficking protein particle complex 8
chr20_-_56284945 0.091 NM_020182
PMEPA1
prostate transmembrane protein, androgen induced 1
chr9_-_4152182 0.088 NM_152629
GLIS3
GLIS family zinc finger 3
chrX_-_33146543 0.088 NM_004010
NM_004009
DMD

dystrophin

chrX_-_31526414 0.087 NM_004014
DMD
dystrophin
chr11_+_12695851 0.087 NM_021961
TEAD1
TEA domain family member 1 (SV40 transcriptional enhancer factor)
chr20_-_56286540 0.087 NM_199171
PMEPA1
prostate transmembrane protein, androgen induced 1
chr7_+_74072007 0.087 NM_001163636
NM_001518
NM_032999
NM_033000
NM_033001
GTF2I




general transcription factor IIi




chr15_+_64388082 0.086 NM_001242933
NM_003099
NM_148955
SNX1


sorting nexin 1


chrX_-_32430370 0.085 NM_004011
NM_004012
DMD

dystrophin

chr3_+_148709140 0.083 NM_001184720
NM_001184721
NM_004130
GYG1


glycogenin 1


chrX_-_33357725 0.082 NM_000109
DMD
dystrophin
chr1_-_52456292 0.082 NM_002867
RAB3B
RAB3B, member RAS oncogene family
chr8_-_54755546 0.082 NM_213620
ATP6V1H
ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H
chr7_-_94285477 0.081 NM_001099400
NM_001099401
NM_003919
SGCE


sarcoglycan, epsilon


chr12_+_65218351 0.081 NM_015279
TBC1D30
TBC1 domain family, member 30
chr7_+_77166750 0.081 NM_002835
PTPN12
protein tyrosine phosphatase, non-receptor type 12
chr9_+_108006892 0.080 NM_080546
SLC44A1
solute carrier family 44, member 1
chr17_-_8534008 0.079 NM_005964
MYH10
myosin, heavy chain 10, non-muscle
chr17_-_30669133 0.079 NM_022344
C17orf75
chromosome 17 open reading frame 75
chr19_+_41903693 0.078 NM_000709
NM_001164783
BCKDHA

branched chain keto acid dehydrogenase E1, alpha polypeptide

chr2_+_242641310 0.078 NM_032329
ING5
inhibitor of growth family, member 5
chr20_-_60640842 0.077 NM_003185
TAF4
TAF4 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 135kDa
chr20_+_57226287 0.076 NM_001001433
NM_001134772
NM_001134773
NM_001204868
NM_003763
STX16-NPEPL1
STX16




STX16-NPEPL1 readthrough (non-protein coding)
syntaxin 16




chr12_-_54653369 0.076 NM_001127321
CBX5
chromobox homolog 5
chr11_+_111848008 0.076 NM_033425
DIXDC1
DIX domain containing 1
chr5_-_74807805 0.074 NM_001130105
COL4A3BP
collagen, type IV, alpha 3 (Goodpasture antigen) binding protein
chr17_-_47439326 0.074 NM_001145365
NM_014897
ZNF652

zinc finger protein 652

chr1_-_94703252 0.072 NM_004815
ARHGAP29
Rho GTPase activating protein 29
chrX_-_31284946 0.071 NM_004015
NM_004016
NM_004017
NM_004018
NM_004019
DMD




dystrophin




chr15_+_38544966 0.070 NM_152594
SPRED1
sprouty-related, EVH1 domain containing 1
chr8_-_54755836 0.070 NM_015941
NM_213619
ATP6V1H

ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H

chr1_-_202777545 0.070 NM_006618
KDM5B
lysine (K)-specific demethylase 5B
chr6_-_136610932 0.070 NM_001077440
NM_001077441
NM_014739
BCLAF1


BCL2-associated transcription factor 1


chrX_-_41782230 0.070 NM_001126054
NM_001126055
NM_003688
CASK


calcium/calmodulin-dependent serine protein kinase (MAGUK family)


chr5_-_74807448 0.069 NM_005713
NM_031361
COL4A3BP

collagen, type IV, alpha 3 (Goodpasture antigen) binding protein

chr11_+_22696318 0.069 NM_005256
GAS2
growth arrest-specific 2
chr7_+_141251077 0.068 NM_018238
AGK
acylglycerol kinase
chr12_+_12869818 0.067 NM_004064
CDKN1B
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
chr11_+_22689653 0.066 NM_177553
GAS2
growth arrest-specific 2
chr14_+_39735500 0.066 NM_001247988
NM_203356
CTAGE5

CTAGE family, member 5

chr10_-_38265452 0.064 NM_145011
ZNF25
zinc finger protein 25
chr15_-_59981517 0.064 NM_004330
BNIP2
BCL2/adenovirus E1B 19kDa interacting protein 2
chr1_-_214724974 0.063 NM_005401
PTPN14
protein tyrosine phosphatase, non-receptor type 14
chr16_+_50186809 0.062 NM_001040284
NM_001040285
PAPD5

PAP associated domain containing 5

chr10_-_25012543 0.062 NM_020824
ARHGAP21
Rho GTPase activating protein 21
chr4_+_123653856 0.061 NM_001178007
NM_152618
BBS12

Bardet-Biedl syndrome 12

chr8_+_42752019 0.061 NM_032410
HOOK3
hook homolog 3 (Drosophila)
chr12_-_54653317 0.061 NM_001127322
CBX5
chromobox homolog 5
chr8_-_11324184 0.060 NM_053279
FAM167A
family with sequence similarity 167, member A
chr12_+_123868608 0.060 NM_020382
SETD8
SET domain containing (lysine methyltransferase) 8
chr13_-_107187312 0.060 NM_004093
EFNB2
ephrin-B2
chr22_+_41347328 0.056 NM_014248
RBX1
ring-box 1, E3 ubiquitin protein ligase
chr1_-_221915458 0.055 NM_007207
NM_144729
DUSP10

dual specificity phosphatase 10

chr19_+_34919213 0.055 NM_005499
UBA2
ubiquitin-like modifier activating enzyme 2
chr1_+_236687026 0.054 NM_201544
LGALS8
lectin, galactoside-binding, soluble, 8
chr7_-_112579726 0.053 NM_152556
C7orf60
chromosome 7 open reading frame 60
chr11_+_22688156 0.053 NM_001143830
GAS2
growth arrest-specific 2
chr5_+_138677517 0.052 NM_016480
PAIP2
poly(A) binding protein interacting protein 2
chr17_+_35294771 0.050 NM_005568
LHX1
LIM homeobox 1
chr3_+_69788562 0.050 NM_198159
MITF
microphthalmia-associated transcription factor
chr1_-_221910801 0.050 NM_144728
DUSP10
dual specificity phosphatase 10
chr15_+_39873276 0.050 NM_003246
THBS1
thrombospondin 1
chr5_-_59995938 0.048 NM_001145208
NM_018369
DEPDC1B

DEP domain containing 1B

chr5_+_138678130 0.048 NM_001033112
PAIP2
poly(A) binding protein interacting protein 2
chr3_-_195808958 0.047 NM_003234
TFRC
transferrin receptor (p90, CD71)
chr2_+_210444364 0.047 NM_002374
NM_031845
NM_031847
MAP2


microtubule-associated protein 2


chr1_+_236681513 0.046 NM_201545
LGALS8
lectin, galactoside-binding, soluble, 8
chr12_-_42538432 0.043 NM_001099650
NM_173601
GXYLT1

glucoside xylosyltransferase 1

chr2_-_230786618 0.043 NM_004238
TRIP12
thyroid hormone receptor interactor 12
chr17_+_17584772 0.043 NM_030665
RAI1
retinoic acid induced 1

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
3.93 1.56e-02 GO:0001944 vasculature development
1.37 1.94e-02 GO:0050794 regulation of cellular process
3.14 2.07e-02 GO:0072358 cardiovascular system development
3.14 2.07e-02 GO:0072359 circulatory system development
3.92 3.18e-02 GO:0001568 blood vessel development

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.27 2.36e-06 GO:0044424 intracellular part
1.26 2.56e-06 GO:0005622 intracellular
1.26 2.64e-03 GO:0043229 intracellular organelle
1.26 2.99e-03 GO:0043226 organelle
1.27 8.44e-03 GO:0043231 intracellular membrane-bounded organelle
1.10 8.79e-03 GO:0044464 cell part
1.41 8.82e-03 GO:0005634 nucleus
1.10 8.87e-03 GO:0005623 cell
1.27 9.02e-03 GO:0043227 membrane-bounded organelle

Nothing significant found in function category.