Motif ID: GUAGUGU

Z-value: 0.805


Mature miRNA associated with seed GUAGUGU:

NamemiRBase Accession
hsa-miR-142-3p MIMAT0000434



Activity profile for motif GUAGUGU.

activity profile for motif GUAGUGU


Sorted Z-values histogram for motif GUAGUGU

Sorted Z-values for motif GUAGUGU



Network of associatons between targets according to the STRING database.



First level regulatory network of GUAGUGU

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr10_-_64578926 1.496 NM_001136178
 EGR2
early growth response 2
chr10_-_64576123 1.371 NM_000399
NM_001136177
NM_001136179
 EGR2


early growth response 2


chr21_-_44846927 1.254 NM_173354
 SIK1
salt-inducible kinase 1
chr9_-_80646150 1.239 NM_002072
 GNAQ
guanine nucleotide binding protein (G protein), q polypeptide
chr6_-_30585016 1.211 NM_002714
 PPP1R10
protein phosphatase 1, regulatory subunit 10
chr3_+_20081523 1.189 NM_003884
 KAT2B
K(lysine) acetyltransferase 2B
chr20_-_45985411 0.897 NM_012408
NM_183047
NM_183048
 ZMYND8


zinc finger, MYND-type containing 8


chr13_+_49684388 0.850 NM_014923
 FNDC3A
fibronectin type III domain containing 3A
chr19_-_17356022 0.771 NM_005234
 NR2F6
nuclear receptor subfamily 2, group F, member 6
chr18_-_33647336 0.758 NM_018170
 RPRD1A
regulation of nuclear pre-mRNA domain containing 1A
chr4_+_87928083 0.744 NM_005935
 AFF1
AF4/FMR2 family, member 1
chr5_-_55290601 0.732 NM_001190981
NM_002184
NM_175767
 IL6ST


interleukin 6 signal transducer (gp130, oncostatin M receptor)


chr6_+_144612872 0.698 NM_007124
 UTRN
utrophin
chr5_+_95066628 0.680 NM_014899
 RHOBTB3
Rho-related BTB domain containing 3
chr10_-_65028825 0.673 NM_004241
 JMJD1C
jumonji domain containing 1C
chr10_-_65225605 0.662 NM_032776
 JMJD1C
jumonji domain containing 1C
chr2_-_99347588 0.656 NM_012214
 MGAT4A
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
chr17_+_47865980 0.654 NM_001199155
NM_001199156
NM_001199157
NM_001199158
NM_007067
 KAT7




K(lysine) acetyltransferase 7




chr3_-_114866090 0.643 NM_015642
 ZBTB20
zinc finger and BTB domain containing 20
chr10_+_5726781 0.628 NM_017782
 FAM208B
family with sequence similarity 208, member B

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 15 of 15 entries
enrichment   p-value GO term description
3.16 4.25e-03 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
3.11 3.76e-04 GO:0007167 enzyme linked receptor protein signaling pathway
2.89 2.56e-02 GO:0045892 negative regulation of transcription, DNA-dependent
2.84 3.42e-02 GO:0051253 negative regulation of RNA metabolic process
2.70 4.32e-02 GO:0010629 negative regulation of gene expression
2.62 4.61e-02 GO:0010558 negative regulation of macromolecule biosynthetic process
2.56 1.29e-02 GO:0046907 intracellular transport
2.51 4.08e-02 GO:0010557 positive regulation of macromolecule biosynthetic process
2.43 8.13e-04 GO:0010604 positive regulation of macromolecule metabolic process
2.30 4.24e-03 GO:0031325 positive regulation of cellular metabolic process
2.29 2.24e-03 GO:0009893 positive regulation of metabolic process
2.24 1.83e-02 GO:0051649 establishment of localization in cell
2.15 1.71e-02 GO:0051641 cellular localization
1.39 3.72e-03 GO:0050794 regulation of cellular process
1.33 3.12e-02 GO:0050789 regulation of biological process

Gene overrepresentation in compartment category:

Showing 1 to 13 of 13 entries
enrichment   p-value GO term description
70.07 4.18e-02 GO:0005955 calcineurin complex
10.62 2.02e-02 GO:0042641 actomyosin
1.75 1.72e-02 GO:0005829 cytosol
1.45 9.23e-04 GO:0005634 nucleus
1.39 1.31e-02 GO:0044446 intracellular organelle part
1.39 1.43e-02 GO:0044422 organelle part
1.31 2.85e-04 GO:0043227 membrane-bounded organelle
1.31 4.99e-04 GO:0043231 intracellular membrane-bounded organelle
1.30 2.75e-05 GO:0043229 intracellular organelle
1.30 3.22e-05 GO:0043226 organelle
1.27 9.05e-07 GO:0044424 intracellular part
1.27 2.09e-02 GO:0005737 cytoplasm
1.25 2.98e-06 GO:0005622 intracellular

Gene overrepresentation in function category:

Showing 1 to 12 of 12 entries
enrichment   p-value GO term description
70.07 6.98e-04 GO:0004924 oncostatin-M receptor activity
70.07 4.92e-02 GO:0004923 leukemia inhibitory factor receptor activity
3.27 2.69e-02 GO:0016564 transcription repressor activity
2.58 2.56e-03 GO:0019899 enzyme binding
2.36 1.45e-03 GO:0030528 transcription regulator activity
1.90 8.94e-04 GO:0008270 zinc ion binding
1.74 7.82e-03 GO:0046914 transition metal ion binding
1.59 9.40e-04 GO:0046872 metal ion binding
1.57 1.48e-03 GO:0043169 cation binding
1.57 1.63e-03 GO:0043167 ion binding
1.40 8.34e-05 GO:0005515 protein binding
1.23 1.40e-05 GO:0005488 binding