Motif ID: HBP1_HMGB_SSRP1_UBTF.p2

Z-value: 1.725


Transcription factors associated with HBP1_HMGB_SSRP1_UBTF.p2:

Gene SymbolEntrez IDGene Name
HBP1 26959 HMG-box transcription factor 1
HMGB2 3148 high-mobility group box 2
HMGB3 3149 high-mobility group box 3
SSRP1 6749 structure specific recognition protein 1
UBTF 7343 upstream binding transcription factor, RNA polymerase I

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.p-valuePlot
HBP1chr7_+_1068094050.909.6e-10Click!
UBTFchr17_-_42297037,
chr17_-_42298228		0.462.1e-02Click!
SSRP1chr11_-_57103324-0.386.3e-02Click!
HMGB2chr4_-_174255454-0.086.9e-01Click!
HMGB3chrX_+_150151757-0.058.1e-01Click!


Activity profile for motif HBP1_HMGB_SSRP1_UBTF.p2.

activity profile for motif HBP1_HMGB_SSRP1_UBTF.p2


Sorted Z-values histogram for motif HBP1_HMGB_SSRP1_UBTF.p2

Sorted Z-values for motif HBP1_HMGB_SSRP1_UBTF.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of HBP1_HMGB_SSRP1_UBTF.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr1_+_84647342 18.148 NM_001242862
 PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr4_-_101439071 15.097 NM_001159694
NM_016242
 EMCN

endomucin

chr2_-_225266710 9.773 NM_001122779
NM_024785
 FAM124B

family with sequence similarity 124B

chr2_-_188312872 9.746 NM_005795
 CALCRL
calcitonin receptor-like
chr4_-_186732047 8.818 NM_001145672
 SORBS2
sorbin and SH3 domain containing 2
chr5_-_111091947 8.376 NM_001142483
 C5orf13
chromosome 5 open reading frame 13
chr18_+_72922725 8.098 NM_005786
 TSHZ1
teashirt zinc finger homeobox 1
chr4_-_186577858 8.071 SORBS2
sorbin and SH3 domain containing 2
chr9_-_14313509 7.892 NFIB
nuclear factor I/B
chr9_-_14313899 7.760 NFIB
nuclear factor I/B
chr5_-_88119604 7.711 NM_001193348
NM_001193349
 MEF2C

myocyte enhancer factor 2C

chr6_-_130031278 7.698 NM_033515
 ARHGAP18
Rho GTPase activating protein 18
chr7_-_11871735 7.528 NM_015204
 THSD7A
thrombospondin, type I, domain containing 7A
chr1_+_61547388 7.483 NM_001145512
 NFIA
nuclear factor I/A
chr1_+_84768333 7.470 NM_001134664
 SAMD13
sterile alpha motif domain containing 13
chr1_+_84630575 7.399 NM_001242860
NM_001242861
 PRKACB

protein kinase, cAMP-dependent, catalytic, beta

chr4_+_41540320 7.214 LIMCH1
LIM and calponin homology domains 1
chr8_-_93075190 7.052 NM_004349
 RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr1_+_100111430 6.793 NM_017734
 PALMD
palmdelphin
chr3_-_149051258 6.135 NM_001184723
NM_138786
 TM4SF18

transmembrane 4 L six family member 18


Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 39 entries
enrichment   p-value GO term description
2.63 1.87e-02 GO:0048706 embryonic skeletal system development
2.44 5.08e-04 GO:0007156 homophilic cell adhesion
2.08 3.47e-02 GO:0009952 anterior/posterior pattern formation
1.87 4.16e-02 GO:0003002 regionalization
1.86 4.40e-03 GO:0016337 cell-cell adhesion
1.79 3.08e-02 GO:0030029 actin filament-based process
1.72 1.77e-02 GO:0016568 chromatin modification
1.72 4.62e-02 GO:0032535 regulation of cellular component size
1.66 4.01e-02 GO:0000122 negative regulation of transcription from RNA polymerase II promoter
1.63 1.78e-02 GO:0006325 chromatin organization
1.60 1.14e-02 GO:0045892 negative regulation of transcription, DNA-dependent
1.59 5.60e-03 GO:0010629 negative regulation of gene expression
1.57 2.67e-02 GO:0051253 negative regulation of RNA metabolic process
1.56 8.66e-03 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
1.54 2.23e-02 GO:0045893 positive regulation of transcription, DNA-dependent
1.51 3.80e-02 GO:0010558 negative regulation of macromolecule biosynthetic process
1.47 4.29e-02 GO:0007155 cell adhesion
1.47 4.29e-02 GO:0022610 biological adhesion
1.44 1.83e-05 GO:0007399 nervous system development
1.44 7.20e-03 GO:0006357 regulation of transcription from RNA polymerase II promoter

Gene overrepresentation in compartment category:

Showing 1 to 13 of 13 entries
enrichment   p-value GO term description
2.27 1.99e-02 GO:0005925 focal adhesion
2.24 1.33e-02 GO:0030055 cell-substrate junction
2.16 4.88e-02 GO:0005924 cell-substrate adherens junction
1.97 3.45e-02 GO:0005912 adherens junction
1.94 2.53e-02 GO:0070161 anchoring junction
1.85 6.62e-03 GO:0016323 basolateral plasma membrane
1.19 2.23e-06 GO:0005634 nucleus
1.09 2.79e-02 GO:0043231 intracellular membrane-bounded organelle
1.08 7.46e-04 GO:0044424 intracellular part
1.08 2.47e-02 GO:0043229 intracellular organelle
1.08 2.92e-02 GO:0043226 organelle
1.08 3.42e-02 GO:0043227 membrane-bounded organelle
1.07 9.51e-04 GO:0005622 intracellular

Gene overrepresentation in function category:

Showing 1 to 10 of 10 entries
enrichment   p-value GO term description
1.65 4.57e-02 GO:0003779 actin binding
1.51 2.97e-02 GO:0008092 cytoskeletal protein binding
1.47 1.75e-02 GO:0005509 calcium ion binding
1.43 1.50e-03 GO:0001071 nucleic acid binding transcription factor activity
1.43 1.50e-03 GO:0003700 sequence-specific DNA binding transcription factor activity
1.43 2.98e-02 GO:0019899 enzyme binding
1.38 1.42e-02 GO:0030528 transcription regulator activity
1.24 1.29e-02 GO:0003677 DNA binding
1.14 4.33e-05 GO:0005515 protein binding
1.08 4.36e-06 GO:0005488 binding