Motif ID: HBP1_HMGB_SSRP1_UBTF.p2

Z-value: 1.725


Transcription factors associated with HBP1_HMGB_SSRP1_UBTF.p2:

Gene SymbolEntrez IDGene Name
HBP1 26959 HMG-box transcription factor 1
HMGB2 3148 high-mobility group box 2
HMGB3 3149 high-mobility group box 3
SSRP1 6749 structure specific recognition protein 1
UBTF 7343 upstream binding transcription factor, RNA polymerase I

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.p-valuePlot
HBP1chr7_+_1068094050.909.6e-10Click!
UBTFchr17_-_42297037,
chr17_-_42298228
0.462.1e-02Click!
SSRP1chr11_-_57103324-0.386.3e-02Click!
HMGB2chr4_-_174255454-0.086.9e-01Click!
HMGB3chrX_+_150151757-0.058.1e-01Click!


Activity profile for motif HBP1_HMGB_SSRP1_UBTF.p2.

activity profile for motif HBP1_HMGB_SSRP1_UBTF.p2


Sorted Z-values histogram for motif HBP1_HMGB_SSRP1_UBTF.p2

Sorted Z-values for motif HBP1_HMGB_SSRP1_UBTF.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of HBP1_HMGB_SSRP1_UBTF.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_+_84647342 18.148 NM_001242862
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr4_-_101439071 15.097 NM_001159694
NM_016242
EMCN

endomucin

chr2_-_225266710 9.773 NM_001122779
NM_024785
FAM124B

family with sequence similarity 124B

chr2_-_188312872 9.746 NM_005795
CALCRL
calcitonin receptor-like
chr4_-_186732047 8.818 NM_001145672
SORBS2
sorbin and SH3 domain containing 2
chr5_-_111091947 8.376 NM_001142483
C5orf13
chromosome 5 open reading frame 13
chr18_+_72922725 8.098 NM_005786
TSHZ1
teashirt zinc finger homeobox 1
chr4_-_186577858 8.071 SORBS2
sorbin and SH3 domain containing 2
chr9_-_14313509 7.892 NFIB
nuclear factor I/B
chr9_-_14313899 7.760 NFIB
nuclear factor I/B
chr5_-_88119604 7.711 NM_001193348
NM_001193349
MEF2C

myocyte enhancer factor 2C

chr6_-_130031278 7.698 NM_033515
ARHGAP18
Rho GTPase activating protein 18
chr7_-_11871735 7.528 NM_015204
THSD7A
thrombospondin, type I, domain containing 7A
chr1_+_61547388 7.483 NM_001145512
NFIA
nuclear factor I/A
chr1_+_84768333 7.470 NM_001134664
SAMD13
sterile alpha motif domain containing 13
chr1_+_84630575 7.399 NM_001242860
NM_001242861
PRKACB

protein kinase, cAMP-dependent, catalytic, beta

chr4_+_41540320 7.214 LIMCH1
LIM and calponin homology domains 1
chr8_-_93075190 7.052 NM_004349
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr1_+_100111430 6.793 NM_017734
PALMD
palmdelphin
chr3_-_149051258 6.135 NM_001184723
NM_138786
TM4SF18

transmembrane 4 L six family member 18

chr4_-_186732208 6.063 NM_001145671
SORBS2
sorbin and SH3 domain containing 2
chr14_-_92413738 6.018 FBLN5
fibulin 5
chr4_+_41614911 5.927 NM_001112719
NM_001112720
LIMCH1

LIM and calponin homology domains 1

chr4_+_41614933 5.741 LIMCH1
LIM and calponin homology domains 1
chr2_+_12857885 5.730 TRIB2
tribbles homolog 2 (Drosophila)
chr9_-_14314036 5.676 NM_001190737
NM_005596
NFIB

nuclear factor I/B

chr8_-_80993009 5.675 NM_001025252
TPD52
tumor protein D52
chr4_+_41700736 5.651 LIMCH1
LIM and calponin homology domains 1
chr4_+_41614725 5.641 LIMCH1
LIM and calponin homology domains 1
chr2_-_157189040 5.555 NM_006186
NR4A2
nuclear receptor subfamily 4, group A, member 2
chr8_-_93029864 5.534 NM_175636
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr1_+_61547625 5.505 NM_001134673
NM_005595
NFIA

nuclear factor I/A

chr19_+_45971249 5.469 NM_001114171
NM_006732
FOSB

FBJ murine osteosarcoma viral oncogene homolog B

chr18_-_53071225 5.295 NM_001243232
TCF4
transcription factor 4
chr17_-_67138013 5.251 NM_080284
ABCA6
ATP-binding cassette, sub-family A (ABC1), member 6
chrX_-_62974341 5.160 ARHGEF9
Cdc42 guanine nucleotide exchange factor (GEF) 9
chr7_-_27183225 5.119 NM_019102
HOXA5
homeobox A5
chr7_+_30960914 5.115 NM_001185060
NM_001185061
NM_001185062
AQP1


aquaporin 1 (Colton blood group)


chr12_+_27397077 5.057 NM_015000
STK38L
serine/threonine kinase 38 like
chr14_-_92414004 4.934 NM_006329
FBLN5
fibulin 5
chrX_-_117107700 4.923 NM_033495
NM_001168300
KLHL13

kelch-like 13 (Drosophila)

chr10_+_112631675 4.879 PDCD4
programmed cell death 4 (neoplastic transformation inhibitor)
chr6_-_76203256 4.641 NM_015687
FILIP1
filamin A interacting protein 1
chr7_+_102553343 4.403 NM_001031692
NM_005824
LRRC17

leucine rich repeat containing 17

chr3_-_66024508 4.349 NM_001033057
NM_004742
NM_015520
MAGI1


membrane associated guanylate kinase, WW and PDZ domain containing 1


chr14_+_77228132 4.293 NM_014909
VASH1
vasohibin 1
chrX_+_86772714 4.285 NM_019117
NM_057162
KLHL4

kelch-like 4 (Drosophila)

chr1_+_221052735 4.269 NM_021958
HLX
H2.0-like homeobox
chrX_+_100333835 4.260 NM_021637
TMEM35
transmembrane protein 35
chr18_-_52988916 4.167 NM_001243234
NM_001243235
TCF4

transcription factor 4

chr3_-_18480203 4.147 NM_001131010
SATB1
SATB homeobox 1
chr15_+_66994669 4.064 NM_005585
SMAD6
SMAD family member 6
chr2_-_165424993 4.050 GRB14
growth factor receptor-bound protein 14
chr4_-_138453628 4.034 NM_019035
PCDH18
protocadherin 18
chr6_-_13408368 4.021 NM_001242630
GFOD1
glucose-fructose oxidoreductase domain containing 1
chr18_-_22930826 4.019


chr4_-_186578122 3.937 NM_001145674
NM_001145675
SORBS2

sorbin and SH3 domain containing 2

chr20_-_45985411 3.915 NM_012408
NM_183047
NM_183048
ZMYND8


zinc finger, MYND-type containing 8


chr12_+_53443834 3.891 NM_170754
TENC1
tensin like C1 domain containing phosphatase (tensin 2)
chr4_+_41540187 3.876 LIMCH1
LIM and calponin homology domains 1
chr17_+_65822206 3.758 BPTF
bromodomain PHD finger transcription factor
chr12_+_13349720 3.710 EMP1
epithelial membrane protein 1
chr18_-_53177999 3.702 NM_001243231
TCF4
transcription factor 4
chr2_+_33359607 3.669 NM_000627
NM_001166264
NM_001166265
NM_001166266
LTBP1



latent transforming growth factor beta binding protein 1



chr13_-_48987247 3.661 LPAR6
lysophosphatidic acid receptor 6
chr1_+_84630014 3.633 NM_001242857
NM_001242858
NM_001242859
PRKACB


protein kinase, cAMP-dependent, catalytic, beta


chrX_+_135251795 3.609 NM_001167819
FHL1
four and a half LIM domains 1
chr10_-_97200895 3.599 NM_001034954
NM_001034955
NM_001034956
NM_001034957
NM_006434
SORBS1




sorbin and SH3 domain containing 1




chr2_+_12856813 3.588 NM_021643
TRIB2
tribbles homolog 2 (Drosophila)
chr1_+_84630374 3.548 PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr17_+_65822242 3.527 BPTF
bromodomain PHD finger transcription factor
chr9_-_14086901 3.464 NFIB
nuclear factor I/B
chr8_-_124553253 3.452 FBXO32
F-box protein 32
chr8_-_17579729 3.371 NM_001001931
MTUS1
microtubule associated tumor suppressor 1
chr3_-_15839674 3.366 NM_001195098
ANKRD28
ankyrin repeat domain 28
chr12_+_14538232 3.364 ATF7IP
activating transcription factor 7 interacting protein
chr8_-_124553448 3.359 NM_001242463
NM_058229
FBXO32

F-box protein 32

chr18_+_20715726 3.349 NM_001100619
CABLES1
Cdk5 and Abl enzyme substrate 1
chrX_-_99891690 3.326 NM_003270
TSPAN6
tetraspanin 6
chr13_-_48987017 3.247 LPAR6
lysophosphatidic acid receptor 6
chr10_+_112631552 3.243 NM_001199492
NM_014456
NM_145341
PDCD4


programmed cell death 4 (neoplastic transformation inhibitor)


chrX_+_135251454 3.242 NM_001159704
FHL1
four and a half LIM domains 1
chr6_+_148663728 3.219 NM_015278
SASH1
SAM and SH3 domain containing 1
chr6_-_32163890 3.193 NOTCH4
notch 4
chr14_-_89883306 3.163 NM_005197
FOXN3
forkhead box N3
chr6_+_143999058 3.145 NM_001100164
NM_001100165
PHACTR2

phosphatase and actin regulator 2

chr2_+_109204904 3.000 NM_001193488
LIMS1
LIM and senescent cell antigen-like domains 1
chr1_+_61869699 2.998 NFIA
nuclear factor I/A
chr13_-_48987652 2.983 NM_001162498
LPAR6
lysophosphatidic acid receptor 6
chr1_+_221052845 2.980 HLX
H2.0-like homeobox
chr4_-_141075232 2.965 NM_018717
MAML3
mastermind-like 3 (Drosophila)
chr2_-_160472960 2.950 NM_013450
BAZ2B
bromodomain adjacent to zinc finger domain, 2B
chr5_+_61874561 2.942 NM_181506
LRRC70
leucine rich repeat containing 70
chr10_+_35426709 2.894 NM_183011
NM_183012
CREM

cAMP responsive element modulator

chr18_+_42260774 2.894 NM_015559
SETBP1
SET binding protein 1
chr20_+_42543417 2.882 NM_001098797
TOX2
TOX high mobility group box family member 2
chr17_+_39382878 2.852 NM_031961
KRTAP9-2
keratin associated protein 9-2
chr9_-_16727887 2.851 BNC2
basonuclin 2
chr1_+_82266081 2.830 NM_012302
LPHN2
latrophilin 2
chr12_-_9268513 2.805 A2M
alpha-2-macroglobulin
chr12_-_9268440 2.785 A2M
alpha-2-macroglobulin
chr6_+_148664124 2.781 SASH1
SAM and SH3 domain containing 1
chr18_-_53257033 2.719 NM_001243227
NM_001243228
TCF4

transcription factor 4

chr1_+_185703470 2.711 NM_031935
HMCN1
hemicentin 1
chr2_-_70475563 2.690 NM_022037
NM_022173
TIA1

TIA1 cytotoxic granule-associated RNA binding protein

chr8_-_93115453 2.678 NM_001198633
NM_175634
RUNX1T1

runt-related transcription factor 1; translocated to, 1 (cyclin D-related)

chr10_-_116444374 2.665 NM_001003407
NM_001003408
ABLIM1

actin binding LIM protein 1

chr9_-_14398981 2.656 NM_001190738
NFIB
nuclear factor I/B
chr1_+_87797371 2.656 LMO4
LIM domain only 4
chr6_+_15246299 2.632 NM_004973
JARID2
jumonji, AT rich interactive domain 2
chr4_+_55523906 2.613 NM_000222
NM_001093772
KIT

v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog

chr18_+_7946885 2.594 PTPRM
protein tyrosine phosphatase, receptor type, M
chr17_-_1248346 2.581 PAFAH1B1
platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
chr6_+_148663953 2.572 SASH1
SAM and SH3 domain containing 1
chr9_+_82187469 2.571 TLE4
transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chr8_-_38205652 2.548 WHSC1L1
Wolf-Hirschhorn syndrome candidate 1-like 1
chr12_+_9142136 2.545 NM_005810
KLRG1
killer cell lectin-like receptor subfamily G, member 1
chr2_+_110656008 2.530 NM_001205288
NM_033514
LIMS3-LOC440895
LIMS3L
LIMS3
LIMS3-LOC440895 readthrough
LIM and senescent cell antigen-like domains 3-like
LIM and senescent cell antigen-like domains 3
chr13_-_74707913 2.526 NM_007249
KLF12
Kruppel-like factor 12
chr2_-_136873740 2.513 NM_001008540
CXCR4
chemokine (C-X-C motif) receptor 4
chr5_-_39424930 2.493 DAB2
disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)
chr1_+_90098693 2.484 LRRC8C
leucine rich repeat containing 8 family, member C
chr2_-_111230651 2.483 NM_001205288
NM_033514
LIMS3-LOC440895
LIMS3L
LIMS3
LIMS3-LOC440895 readthrough
LIM and senescent cell antigen-like domains 3-like
LIM and senescent cell antigen-like domains 3
chr10_+_63661012 2.480 NM_032199
ARID5B
AT rich interactive domain 5B (MRF1-like)
chr5_-_111092918 2.476 NM_004772
C5orf13
chromosome 5 open reading frame 13
chr10_+_35416089 2.456 CREM
cAMP responsive element modulator
chr9_-_98268866 2.422 PTCH1
patched 1
chr9_+_2015218 2.410 NM_003070
NM_139045
SMARCA2

SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2

chr11_+_123986103 2.409 NM_001130142
NM_014622
NM_198315
VWA5A


von Willebrand factor A domain containing 5A


chr12_+_20724797 2.394 NM_001244683
PDE3A
phosphodiesterase 3A, cGMP-inhibited
chr5_-_39425297 2.387 NM_001244871
NM_001343
DAB2

disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)

chr3_+_134514044 2.385 NM_004441
EPHB1
EPH receptor B1
chr5_+_139028483 2.370 CXXC5
CXXC finger protein 5
chr1_+_163038564 2.368 NM_005613
RGS4
regulator of G-protein signaling 4
chr5_-_88199868 2.350 NM_001131005
NM_001193347
MEF2C

myocyte enhancer factor 2C

chr6_+_136172802 2.349 NM_018945
PDE7B
phosphodiesterase 7B
chr8_-_93107442 2.337 NM_001198629
NM_001198630
NM_001198632
NM_175635
RUNX1T1



runt-related transcription factor 1; translocated to, 1 (cyclin D-related)



chr12_-_42877743 2.271 PRICKLE1
prickle homolog 1 (Drosophila)
chr5_-_39425030 2.268 DAB2
disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)
chr5_+_138677546 2.257 PAIP2
poly(A) binding protein interacting protein 2
chr4_+_170581212 2.254 NM_001243374
CLCN3
chloride channel 3
chr2_+_33701320 2.241 NM_001139488
RASGRP3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr12_+_79439432 2.238 NM_001135806
SYT1
synaptotagmin I
chr14_-_23288912 2.218 NM_001126106
SLC7A7
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr9_-_140196702 2.210 NM_001004354
NRARP
NOTCH-regulated ankyrin repeat protein
chr18_-_45663667 2.202 NM_001039360
ZBTB7C
zinc finger and BTB domain containing 7C
chr1_+_66458389 2.174 NM_001037340
PDE4B
phosphodiesterase 4B, cAMP-specific
chr2_+_69240137 2.160 NM_018153
NM_032208
NM_053034
ANTXR1


anthrax toxin receptor 1


chr6_-_111888520 2.146 NM_001164283
TRAF3IP2
TRAF3 interacting protein 2
chr5_+_140571903 2.143 NM_018930
PCDHB10
protocadherin beta 10
chr13_-_74708361 2.141 KLF12
Kruppel-like factor 12
chr12_-_9268475 2.140 A2M
alpha-2-macroglobulin
chr12_+_32654976 2.134 NM_139241
FGD4
FYVE, RhoGEF and PH domain containing 4
chrX_-_135863033 2.117 ARHGEF6
Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
chr12_-_42877785 2.112 NM_001144882
NM_001144883
PRICKLE1

prickle homolog 1 (Drosophila)

chr2_+_33701678 2.112 RASGRP3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr6_+_119215240 2.106 NM_014034
ASF1A
ASF1 anti-silencing function 1 homolog A (S. cerevisiae)
chr1_+_221053000 2.059 HLX
H2.0-like homeobox
chr13_+_111855406 2.054 ARHGEF7
Rho guanine nucleotide exchange factor (GEF) 7
chr5_-_111312522 2.046 NM_001142474
NM_001142475
C5orf13

chromosome 5 open reading frame 13

chr9_-_8733893 2.039 NM_001040712
NM_001171025
NM_130391
NM_130392
NM_130393
PTPRD




protein tyrosine phosphatase, receptor type, D




chr1_+_150337145 2.036 RPRD2
regulation of nuclear pre-mRNA domain containing 2
chr4_+_78078394 2.026 CCNG2
cyclin G2
chr5_+_138677570 2.025 PAIP2
poly(A) binding protein interacting protein 2
chr2_-_74667553 2.022 NM_001015056
NM_033046
RTKN

rhotekin

chr2_+_109204745 2.018 NM_004987
LIMS1
LIM and senescent cell antigen-like domains 1
chr2_+_203499819 2.017 NM_173511
FAM117B
family with sequence similarity 117, member B
chr2_+_109204777 1.989 LIMS1
LIM and senescent cell antigen-like domains 1
chrX_-_135863502 1.977 NM_004840
ARHGEF6
Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
chr20_+_30598244 1.976 NM_080625
C20orf160
chromosome 20 open reading frame 160
chr1_+_90098643 1.972 NM_032270
LRRC8C
leucine rich repeat containing 8 family, member C
chr14_+_21156922 1.971 NM_001097577
NM_194431
ANG
RNASE4
angiogenin, ribonuclease, RNase A family, 5
ribonuclease, RNase A family, 4
chrX_-_10645726 1.964 NM_001098624
MID1
midline 1 (Opitz/BBB syndrome)
chr9_-_107690526 1.951 NM_005502
ABCA1
ATP-binding cassette, sub-family A (ABC1), member 1
chr9_+_82187599 1.947 TLE4
transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chr12_+_13349601 1.922 NM_001423
EMP1
epithelial membrane protein 1
chrX_-_135863104 1.922 ARHGEF6
Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
chr3_-_187454247 1.918 NM_001130845
BCL6
B-cell CLL/lymphoma 6
chr18_-_53089722 1.908 NM_001243233
TCF4
transcription factor 4
chr3_+_25469833 1.906 NM_000965
RARB
retinoic acid receptor, beta
chr1_+_84609941 1.904 NM_182948
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr1_-_234743488 1.902 IRF2BP2
interferon regulatory factor 2 binding protein 2
chr15_-_70994608 1.901 NM_001008224
UACA
uveal autoantigen with coiled-coil domains and ankyrin repeats
chrX_-_135749436 1.898 ARHGEF6
Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
chr1_+_150039341 1.898 NM_007259
VPS45
vacuolar protein sorting 45 homolog (S. cerevisiae)
chr1_+_150336584 1.889 RPRD2
regulation of nuclear pre-mRNA domain containing 2
chr6_+_144612872 1.884 NM_007124
UTRN
utrophin
chr10_-_116286661 1.883 NM_006720
ABLIM1
actin binding LIM protein 1
chr6_+_153019029 1.879 NM_025107
MYCT1
myc target 1
chr3_-_112359443 1.872 CCDC80
coiled-coil domain containing 80
chr17_-_66951381 1.871 NM_007168
ABCA8
ATP-binding cassette, sub-family A (ABC1), member 8
chr10_-_11574273 1.866 NM_001080491
USP6NL
USP6 N-terminal like
chr3_-_114866090 1.864 NM_015642
ZBTB20
zinc finger and BTB domain containing 20
chr8_+_70405080 1.862 SULF1
sulfatase 1
chr7_+_80267782 1.862 NM_000072
NM_001001548
CD36

CD36 molecule (thrombospondin receptor)

chr13_-_72441312 1.858 NM_004392
NM_080759
NM_080760
DACH1


dachshund homolog 1 (Drosophila)


chr2_+_181845803 1.847 UBE2E3
ubiquitin-conjugating enzyme E2E 3
chr4_-_186877413 1.841 SORBS2
sorbin and SH3 domain containing 2
chr11_+_33563772 1.821 NM_012194
C11orf41
chromosome 11 open reading frame 41
chr5_+_68800003 1.819 NM_001205255
OCLN
occludin

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.32 4.59e-10 GO:0032502 developmental process
1.33 5.02e-09 GO:0007275 multicellular organismal development
1.32 1.32e-07 GO:0048856 anatomical structure development
1.33 5.61e-07 GO:0048731 system development
1.44 1.83e-05 GO:0007399 nervous system development
1.34 5.12e-05 GO:0048523 negative regulation of cellular process
1.34 9.96e-05 GO:0048869 cellular developmental process
1.14 1.28e-04 GO:0065007 biological regulation
1.34 1.65e-04 GO:0030154 cell differentiation
1.15 3.71e-04 GO:0050794 regulation of cellular process
1.30 3.95e-04 GO:0048519 negative regulation of biological process
2.44 5.08e-04 GO:0007156 homophilic cell adhesion
1.18 7.02e-04 GO:0032501 multicellular organismal process
1.13 1.00e-03 GO:0050789 regulation of biological process
1.37 2.21e-03 GO:0009653 anatomical structure morphogenesis
1.86 4.40e-03 GO:0016337 cell-cell adhesion
1.59 5.60e-03 GO:0010629 negative regulation of gene expression
1.26 6.86e-03 GO:0048522 positive regulation of cellular process
1.44 7.20e-03 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.56 8.66e-03 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
1.60 1.14e-02 GO:0045892 negative regulation of transcription, DNA-dependent
1.20 1.63e-02 GO:0023052 signaling
1.07 1.69e-02 GO:0009987 cellular process
1.72 1.77e-02 GO:0016568 chromatin modification
1.63 1.78e-02 GO:0006325 chromatin organization
2.63 1.87e-02 GO:0048706 embryonic skeletal system development
1.54 2.23e-02 GO:0045893 positive regulation of transcription, DNA-dependent
1.57 2.67e-02 GO:0051253 negative regulation of RNA metabolic process
1.25 2.91e-02 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.79 3.08e-02 GO:0030029 actin filament-based process
2.08 3.47e-02 GO:0009952 anterior/posterior pattern formation
1.20 3.70e-02 GO:0007165 signal transduction
1.51 3.80e-02 GO:0010558 negative regulation of macromolecule biosynthetic process
1.66 4.01e-02 GO:0000122 negative regulation of transcription from RNA polymerase II promoter
1.87 4.16e-02 GO:0003002 regionalization
1.47 4.29e-02 GO:0007155 cell adhesion
1.47 4.29e-02 GO:0022610 biological adhesion
1.25 4.48e-02 GO:0051252 regulation of RNA metabolic process
1.72 4.62e-02 GO:0032535 regulation of cellular component size

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.19 2.23e-06 GO:0005634 nucleus
1.08 7.46e-04 GO:0044424 intracellular part
1.07 9.51e-04 GO:0005622 intracellular
1.85 6.62e-03 GO:0016323 basolateral plasma membrane
2.24 1.33e-02 GO:0030055 cell-substrate junction
2.27 1.99e-02 GO:0005925 focal adhesion
1.08 2.47e-02 GO:0043229 intracellular organelle
1.94 2.53e-02 GO:0070161 anchoring junction
1.09 2.79e-02 GO:0043231 intracellular membrane-bounded organelle
1.08 2.92e-02 GO:0043226 organelle
1.08 3.42e-02 GO:0043227 membrane-bounded organelle
1.97 3.45e-02 GO:0005912 adherens junction
2.16 4.88e-02 GO:0005924 cell-substrate adherens junction

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.08 4.36e-06 GO:0005488 binding
1.14 4.33e-05 GO:0005515 protein binding
1.43 1.50e-03 GO:0001071 nucleic acid binding transcription factor activity
1.43 1.50e-03 GO:0003700 sequence-specific DNA binding transcription factor activity
1.24 1.29e-02 GO:0003677 DNA binding
1.38 1.42e-02 GO:0030528 transcription regulator activity
1.47 1.75e-02 GO:0005509 calcium ion binding
1.51 2.97e-02 GO:0008092 cytoskeletal protein binding
1.43 2.98e-02 GO:0019899 enzyme binding
1.65 4.57e-02 GO:0003779 actin binding