Motif ID: HES1.p2

Z-value: 1.139


Transcription factors associated with HES1.p2:

Gene SymbolEntrez IDGene Name
HES1 3280 hairy and enhancer of split 1, (Drosophila)

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.p-valuePlot
HES1chr3_+_1938539370.096.7e-01Click!


Activity profile for motif HES1.p2.

activity profile for motif HES1.p2


Sorted Z-values histogram for motif HES1.p2

Sorted Z-values for motif HES1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of HES1.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr7_+_155089614 2.002 INSIG1
insulin induced gene 1
chr18_+_20715726 1.862 NM_001100619
 CABLES1
Cdk5 and Abl enzyme substrate 1
chr2_-_86116016 1.291 NM_003896
 ST3GAL5
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
chr7_+_155089483 1.206 NM_005542
NM_198336
NM_198337
 INSIG1


insulin induced gene 1


chr6_-_35109003 1.159 NM_001093728
NM_018679
 TCP11

t-complex 11 homolog (mouse)

chr1_-_231175971 1.097 NM_198552
 FAM89A
family with sequence similarity 89, member A
chr13_-_77460432 0.980 NM_138444
 KCTD12
potassium channel tetramerisation domain containing 12
chr13_+_21277481 0.953 NM_138284
 IL17D
interleukin 17D
chr8_+_38614756 0.831 TACC1
transforming, acidic coiled-coil containing protein 1
chr12_+_57482886 0.827 NAB2
NGFI-A binding protein 2 (EGR1 binding protein 2)
chr19_+_39833096 0.802 SAMD4B
sterile alpha motif domain containing 4B
chr15_+_67813466 0.757 NM_001143936
 C15orf61
chromosome 15 open reading frame 61
chr13_+_42031679 0.755 C13orf15
chromosome 13 open reading frame 15
chr17_-_57184116 0.750 TRIM37
tripartite motif containing 37
chrX_+_150863729 0.743 NM_024082
 PRRG3
proline rich Gla (G-carboxyglutamic acid) 3 (transmembrane)
chr17_+_35849950 0.736 NM_007026
 DUSP14
dual specificity phosphatase 14
chr1_-_36184392 0.710 C1orf216
chromosome 1 open reading frame 216
chr18_-_500583 0.708 NM_130386
 COLEC12
collectin sub-family member 12
chr12_+_8850479 0.705 NM_020734
 RIMKLB
ribosomal modification protein rimK-like family member B
chr7_-_91763775 0.703 CYP51A1
cytochrome P450, family 51, subfamily A, polypeptide 1

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 17 of 17 entries
enrichment   p-value GO term description
1.69 2.74e-02 GO:0032446 protein modification by small protein conjugation
1.40 1.33e-08 GO:0006464 protein modification process
1.38 4.65e-08 GO:0043412 macromolecule modification
1.33 2.45e-08 GO:0044267 cellular protein metabolic process
1.31 8.87e-07 GO:0044249 cellular biosynthetic process
1.30 1.04e-06 GO:0009058 biosynthetic process
1.28 1.82e-13 GO:0044260 cellular macromolecule metabolic process
1.26 4.20e-02 GO:0034645 cellular macromolecule biosynthetic process
1.24 9.17e-17 GO:0044237 cellular metabolic process
1.23 1.24e-03 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.21 3.52e-04 GO:0006807 nitrogen compound metabolic process
1.21 1.12e-03 GO:0034641 cellular nitrogen compound metabolic process
1.21 1.63e-03 GO:0019538 protein metabolic process
1.20 2.48e-11 GO:0044238 primary metabolic process
1.20 3.30e-07 GO:0043170 macromolecule metabolic process
1.18 8.47e-12 GO:0008152 metabolic process
1.09 8.19e-06 GO:0009987 cellular process

Gene overrepresentation in compartment category:

Showing 1 to 20 of 21 entries
enrichment   p-value GO term description
1.58 1.11e-02 GO:0019866 organelle inner membrane
1.32 5.53e-04 GO:0005739 mitochondrion
1.29 1.46e-05 GO:0031090 organelle membrane
1.22 2.04e-03 GO:0031974 membrane-enclosed lumen
1.22 2.87e-03 GO:0070013 intracellular organelle lumen
1.22 6.46e-03 GO:0044428 nuclear part
1.21 2.14e-12 GO:0044444 cytoplasmic part
1.21 6.60e-03 GO:0043233 organelle lumen
1.21 1.80e-02 GO:0005829 cytosol
1.19 6.32e-21 GO:0043231 intracellular membrane-bounded organelle
1.19 7.41e-21 GO:0043227 membrane-bounded organelle
1.19 1.47e-08 GO:0005634 nucleus
1.19 1.73e-08 GO:0044446 intracellular organelle part
1.17 1.81e-07 GO:0044422 organelle part
1.15 2.21e-17 GO:0043226 organelle
1.15 2.83e-17 GO:0043229 intracellular organelle
1.15 6.12e-12 GO:0005737 cytoplasm
1.13 1.68e-20 GO:0044424 intracellular part
1.13 2.07e-20 GO:0005622 intracellular
1.03 4.31e-02 GO:0044464 cell part

Gene overrepresentation in function category:

Showing 1 to 18 of 18 entries
enrichment   p-value GO term description
1.55 2.98e-03 GO:0019904 protein domain specific binding
1.45 6.57e-03 GO:0004672 protein kinase activity
1.42 4.16e-03 GO:0016773 phosphotransferase activity, alcohol group as acceptor
1.41 2.91e-03 GO:0016301 kinase activity
1.39 1.21e-03 GO:0016772 transferase activity, transferring phosphorus-containing groups
1.36 3.84e-07 GO:0016740 transferase activity
1.34 4.67e-02 GO:0003723 RNA binding
1.27 8.45e-03 GO:0030554 adenyl nucleotide binding
1.26 1.96e-02 GO:0032559 adenyl ribonucleotide binding
1.25 2.17e-04 GO:0000166 nucleotide binding
1.25 3.96e-02 GO:0005524 ATP binding
1.23 1.95e-02 GO:0017076 purine nucleotide binding
1.22 3.76e-02 GO:0032553 ribonucleotide binding
1.22 3.76e-02 GO:0032555 purine ribonucleotide binding
1.17 5.20e-06 GO:0003824 catalytic activity
1.17 1.79e-02 GO:0003676 nucleic acid binding
1.14 1.48e-06 GO:0005515 protein binding
1.08 6.45e-08 GO:0005488 binding