Motif ID: HLF.p2

Z-value: 0.735


Transcription factors associated with HLF.p2:

Gene SymbolEntrez IDGene Name
HLF 3131 hepatic leukemia factor

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.p-valuePlot
HLFchr17_+_533423560.154.9e-01Click!


Activity profile for motif HLF.p2.

activity profile for motif HLF.p2


Sorted Z-values histogram for motif HLF.p2

Sorted Z-values for motif HLF.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of HLF.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr16_+_57406398 4.602 NM_002996
 CX3CL1
chemokine (C-X3-C motif) ligand 1
chr12_-_105322056 3.476 NM_032148
 SLC41A2
solute carrier family 41, member 2
chr2_+_152214105 2.226 NM_007115
 TNFAIP6
tumor necrosis factor, alpha-induced protein 6
chr19_+_45504686 2.007 NM_006509
 RELB
v-rel reticuloendotheliosis viral oncogene homolog B
chr1_-_173174611 1.903 TNFSF4
tumor necrosis factor (ligand) superfamily, member 4
chr9_+_111624545 1.741 NM_006687
 ACTL7A
actin-like 7A
chr4_+_74702272 1.609 NM_002993
 CXCL6
chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2)
chr12_+_124773709 1.545 NM_181709
 FAM101A
family with sequence similarity 101, member A
chr11_-_64647136 1.491 EHD1
EH-domain containing 1
chr12_-_117319231 1.235 NM_003806
 HRK
harakiri, BCL2 interacting protein (contains only BH3 domain)
chr15_-_80263460 1.176 NM_001114735
NM_004049
 BCL2A1

BCL2-related protein A1

chr6_-_169654047 1.158 NM_003247
 THBS2
thrombospondin 2
chr5_-_58882274 1.148 NM_006203
 PDE4D
phosphodiesterase 4D, cAMP-specific
chr18_+_61554938 1.129 NM_001143818
NM_002575
 SERPINB2

serpin peptidase inhibitor, clade B (ovalbumin), member 2

chr6_-_169653922 1.092 THBS2
thrombospondin 2
chr1_-_8003224 1.088 NM_001561
 TNFRSF9
tumor necrosis factor receptor superfamily, member 9
chr10_-_14372807 1.006 NM_018027
 FRMD4A
FERM domain containing 4A
chr7_-_83824216 0.977 NM_006080
 SEMA3A
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr17_+_34431219 0.971 NM_002984
 CCL4
chemokine (C-C motif) ligand 4
chr13_+_97928414 0.963 MBNL2
muscleblind-like 2 (Drosophila)

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 18 of 18 entries
enrichment   p-value GO term description
19.88 1.30e-04 GO:0060678 dichotomous subdivision of terminal units involved in ureteric bud branching
17.68 3.79e-04 GO:0048880 sensory system development
17.68 3.79e-04 GO:0048892 lateral line nerve development
17.68 3.79e-04 GO:0048895 lateral line nerve glial cell differentiation
17.68 3.79e-04 GO:0048925 lateral line system development
17.68 3.79e-04 GO:0048937 lateral line nerve glial cell development
17.68 3.79e-04 GO:0050935 iridophore differentiation
16.87 5.35e-05 GO:0060600 dichotomous subdivision of an epithelial terminal unit
13.26 3.78e-03 GO:0048846 axon extension involved in axon guidance
13.26 3.78e-03 GO:0090184 positive regulation of kidney development
12.37 9.15e-04 GO:0048485 sympathetic nervous system development
10.61 1.86e-02 GO:0030513 positive regulation of BMP signaling pathway
10.61 1.86e-02 GO:0048484 enteric nervous system development
8.84 1.36e-02 GO:0030318 melanocyte differentiation
8.84 1.36e-02 GO:0050931 pigment cell differentiation
7.07 1.93e-02 GO:0048066 developmental pigmentation
1.79 3.35e-02 GO:0009611 response to wounding
1.76 3.11e-02 GO:0009605 response to external stimulus

Gene overrepresentation in compartment category:

Showing 1 to 3 of 3 entries
enrichment   p-value GO term description
1.96 3.87e-04 GO:0005615 extracellular space
1.73 4.11e-03 GO:0044421 extracellular region part
1.46 1.00e-02 GO:0005576 extracellular region

Gene overrepresentation in function category:

Showing 1 to 2 of 2 entries
enrichment   p-value GO term description
5.76 2.80e-03 GO:0008009 chemokine activity
5.20 7.41e-03 GO:0042379 chemokine receptor binding