Motif ID: HNF1A.p2

Z-value: 0.864


Transcription factors associated with HNF1A.p2:

Gene SymbolEntrez IDGene Name
HNF1A 6927 HNF1 homeobox A

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.p-valuePlot
HNF1Achr12_+_1214165480.368.1e-02Click!


Activity profile for motif HNF1A.p2.

activity profile for motif HNF1A.p2


Sorted Z-values histogram for motif HNF1A.p2

Sorted Z-values for motif HNF1A.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of HNF1A.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr20_+_43029973 1.659 HNF4A
hepatocyte nuclear factor 4, alpha
chr22_+_32439103 1.348 SLC5A1
solute carrier family 5 (sodium/glucose cotransporter), member 1
chr22_+_32439211 1.343 SLC5A1
solute carrier family 5 (sodium/glucose cotransporter), member 1
chr13_+_97874704 1.060 MBNL2
muscleblind-like 2 (Drosophila)
chr16_-_66952729 1.050 NM_001204744
NM_001204745
NM_001204746
NM_004062
 CDH16



cadherin 16, KSP-cadherin



chr2_+_152214105 1.044 NM_007115
 TNFAIP6
tumor necrosis factor, alpha-induced protein 6
chr6_+_29274402 0.885 NM_030946
 OR14J1
olfactory receptor, family 14, subfamily J, member 1
chr15_+_67418053 0.877 NM_001145102
 SMAD3
SMAD family member 3
chr22_+_32439250 0.800 SLC5A1
solute carrier family 5 (sodium/glucose cotransporter), member 1
chr9_+_82186846 0.673 NM_007005
 TLE4
transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chr1_+_48688356 0.662 NM_001011547
NM_001135181
 SLC5A9

solute carrier family 5 (sodium/glucose cotransporter), member 9

chr22_-_38506532 0.660 BAIAP2L2
BAI1-associated protein 2-like 2
chr14_+_55168831 0.649 SAMD4A
sterile alpha motif domain containing 4A
chr16_-_69385656 0.640 NM_144676
 TMED6
transmembrane emp24 protein transport domain containing 6
chr4_+_74347461 0.629 NM_001133
 AFM
afamin
chr19_+_799281 0.625 PTBP1
polypyrimidine tract binding protein 1
chr14_+_95027760 0.619 NM_006215
 SERPINA4
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4
chr3_-_161089747 0.619 NM_001040100
 SPTSSB
serine palmitoyltransferase, small subunit B
chr14_+_68168602 0.612 NM_152443
 RDH12
retinol dehydrogenase 12 (all-trans/9-cis/11-cis)
chr1_+_119911395 0.599 NM_001005783
NM_016527
 HAO2

hydroxyacid oxidase 2 (long chain)


Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 12 of 12 entries
enrichment   p-value GO term description
53.44 7.63e-03 GO:0034392 negative regulation of smooth muscle cell apoptosis
11.45 1.29e-02 GO:0030195 negative regulation of blood coagulation
11.06 1.61e-02 GO:0050819 negative regulation of coagulation
9.59 8.23e-03 GO:0030193 regulation of blood coagulation
8.91 1.38e-02 GO:0050818 regulation of coagulation
7.80 3.41e-02 GO:0061041 regulation of wound healing
4.82 9.17e-03 GO:0006805 xenobiotic metabolic process
4.82 9.17e-03 GO:0071466 cellular response to xenobiotic stimulus
4.79 9.91e-03 GO:0009410 response to xenobiotic stimulus
2.99 6.66e-03 GO:0071702 organic substance transport
2.50 3.31e-02 GO:0042060 wound healing
2.17 3.22e-02 GO:0009611 response to wounding

Gene overrepresentation in compartment category:

Showing 1 to 12 of 12 entries
enrichment   p-value GO term description
7.96 5.07e-03 GO:0031093 platelet alpha granule lumen
7.80 5.84e-03 GO:0034774 secretory granule lumen
7.48 7.67e-03 GO:0060205 cytoplasmic membrane-bounded vesicle lumen
7.20 9.95e-03 GO:0031983 vesicle lumen
7.13 3.66e-02 GO:0005903 brush border
6.57 1.82e-02 GO:0031091 platelet alpha granule
4.14 3.52e-03 GO:0016324 apical plasma membrane
3.80 2.24e-03 GO:0045177 apical part of cell
2.51 1.17e-04 GO:0005615 extracellular space
2.21 4.56e-04 GO:0044421 extracellular region part
1.74 2.09e-03 GO:0005576 extracellular region
1.65 8.31e-03 GO:0044459 plasma membrane part

Gene overrepresentation in function category:

Showing 1 to 4 of 4 entries
enrichment   p-value GO term description
15.27 3.10e-02 GO:0005355 glucose transmembrane transporter activity
14.25 4.16e-02 GO:0008514 organic anion transmembrane transporter activity
7.29 4.76e-02 GO:0043498 cell surface binding
2.83 2.39e-02 GO:0022804 active transmembrane transporter activity