Motif ID: HOX{A6,A7,B6,B7}.p2

Z-value: 1.707


Transcription factors associated with HOX{A6,A7,B6,B7}.p2:

Gene SymbolEntrez IDGene Name
HOXA6 3203 homeobox A6
HOXA7 3204 homeobox A7
HOXB6 3216 homeobox B6
HOXB7 3217 homeobox B7

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.p-valuePlot
HOXB7chr17_-_466879250.817.9e-07Click!
HOXA7chr7_-_271961630.681.8e-04Click!
HOXB6chr17_-_46682333-0.358.6e-02Click!
HOXA6chr7_-_271873670.331.0e-01Click!


Activity profile for motif HOX{A6,A7,B6,B7}.p2.

activity profile for motif HOX{A6,A7,B6,B7}.p2


Sorted Z-values histogram for motif HOX{A6,A7,B6,B7}.p2

Sorted Z-values for motif HOX{A6,A7,B6,B7}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of HOX{A6,A7,B6,B7}.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr9_-_14086901 31.534 NFIB
nuclear factor I/B
chr1_+_61869699 20.504 NFIA
nuclear factor I/A
chr1_+_84630575 16.138 NM_001242860
NM_001242861
PRKACB

protein kinase, cAMP-dependent, catalytic, beta

chr1_+_84630014 13.228 NM_001242857
NM_001242858
NM_001242859
PRKACB


protein kinase, cAMP-dependent, catalytic, beta


chr5_-_88119604 13.158 NM_001193348
NM_001193349
MEF2C

myocyte enhancer factor 2C

chr4_+_41614725 12.921 LIMCH1
LIM and calponin homology domains 1
chr4_+_41614911 12.479 NM_001112719
NM_001112720
LIMCH1

LIM and calponin homology domains 1

chr4_+_41614933 12.047 LIMCH1
LIM and calponin homology domains 1
chr5_-_88199868 11.429 NM_001131005
NM_001193347
MEF2C

myocyte enhancer factor 2C

chr4_-_186877869 9.282 NM_021069
SORBS2
sorbin and SH3 domain containing 2
chr4_+_41700736 8.931 LIMCH1
LIM and calponin homology domains 1
chr3_-_64211111 8.079 NM_198859
PRICKLE2
prickle homolog 2 (Drosophila)
chr1_+_84630374 7.782 PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr7_-_27183225 7.186 NM_019102
HOXA5
homeobox A5
chr8_-_93107442 7.175 NM_001198629
NM_001198630
NM_001198632
NM_175635
RUNX1T1



runt-related transcription factor 1; translocated to, 1 (cyclin D-related)



chr1_+_61547388 6.550 NM_001145512
NFIA
nuclear factor I/A
chr14_-_54423448 6.538 NM_001202
NM_130850
BMP4

bone morphogenetic protein 4

chr18_-_53089722 6.461 NM_001243233
TCF4
transcription factor 4
chr1_+_100111430 6.451 NM_017734
PALMD
palmdelphin
chr4_-_186733372 6.374 NM_003603
NM_001145670
SORBS2

sorbin and SH3 domain containing 2

chr18_-_22932109 6.317 NM_015461
ZNF521
zinc finger protein 521
chr5_-_88179278 6.133 NM_001193350
NM_002397
MEF2C

myocyte enhancer factor 2C

chr8_-_80993009 6.021 NM_001025252
TPD52
tumor protein D52
chr18_-_22931970 5.807 ZNF521
zinc finger protein 521
chr9_-_8733893 5.432 NM_001040712
NM_001171025
NM_130391
NM_130392
NM_130393
PTPRD




protein tyrosine phosphatase, receptor type, D




chr6_-_76203256 5.416 NM_015687
FILIP1
filamin A interacting protein 1
chr1_+_84767288 5.268 NM_001134663
SAMD13
sterile alpha motif domain containing 13
chr18_+_20735788 5.242 NM_138375
CABLES1
Cdk5 and Abl enzyme substrate 1
chr11_+_87032428 5.166 TMEM135
transmembrane protein 135
chr9_+_2015218 5.126 NM_003070
NM_139045
SMARCA2

SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2

chr6_+_136172802 4.913 NM_018945
PDE7B
phosphodiesterase 7B
chr1_+_84647342 4.869 NM_001242862
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr7_-_27205123 4.749 HOXA9
homeobox A9
chr10_-_116392099 4.689 ABLIM1
actin binding LIM protein 1
chr7_-_27166638 4.630 NM_153631
HOXA3
homeobox A3
chr4_-_16900348 4.481 NM_001130834
NM_001290
LDB2

LIM domain binding 2

chr1_+_212475147 4.441 NM_001199756
PPP2R5A
protein phosphatase 2, regulatory subunit B', alpha
chr5_-_111091947 4.349 NM_001142483
C5orf13
chromosome 5 open reading frame 13
chr13_-_72441312 4.221 NM_004392
NM_080759
NM_080760
DACH1


dachshund homolog 1 (Drosophila)


chr10_-_116418056 4.219 NM_002313
ABLIM1
actin binding LIM protein 1
chr8_-_93107643 4.205 RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr18_+_72922725 4.197 NM_005786
TSHZ1
teashirt zinc finger homeobox 1
chr1_+_78470593 4.093 NM_007034
DNAJB4
DnaJ (Hsp40) homolog, subfamily B, member 4
chr2_-_183387063 4.082 NM_005019
NM_001003683
PDE1A

phosphodiesterase 1A, calmodulin-dependent

chr1_+_84609941 4.019 NM_182948
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr17_-_46687925 3.995 HOXB7
homeobox B7
chr7_-_27205148 3.970 NM_152739
HOXA9
homeobox A9
chr3_-_15839674 3.938 NM_001195098
ANKRD28
ankyrin repeat domain 28
chrX_-_117119282 3.870 NM_001168299
KLHL13
kelch-like 13 (Drosophila)
chr1_+_61547625 3.808 NM_001134673
NM_005595
NFIA

nuclear factor I/A

chr3_+_25470067 3.709 RARB
retinoic acid receptor, beta
chr10_+_35426709 3.701 NM_183011
NM_183012
CREM

cAMP responsive element modulator

chr15_+_57511616 3.683 NM_207040
TCF12
transcription factor 12
chr20_-_45976626 3.648 ZMYND8
zinc finger, MYND-type containing 8
chr2_-_165424993 3.635 GRB14
growth factor receptor-bound protein 14
chr2_-_188312872 3.580 NM_005795
CALCRL
calcitonin receptor-like
chrX_+_135251795 3.562 NM_001167819
FHL1
four and a half LIM domains 1
chr2_+_66662692 3.553 MEIS1
Meis homeobox 1
chr7_-_14025826 3.405 NM_001163150
NM_001163151
NM_001163152
ETV1


ets variant 1


chr13_+_58205943 3.384 PCDH17
protocadherin 17
chr8_-_93107881 3.355 NM_001198625
NM_001198626
NM_001198627
NM_001198631
NM_001198634
NM_001198679
RUNX1T1





runt-related transcription factor 1; translocated to, 1 (cyclin D-related)





chr13_+_36050885 3.352 NM_001204197
NBEA
neurobeachin
chr10_+_35456443 3.247 NM_182771
NM_182772
CREM

cAMP responsive element modulator

chr11_-_27742224 3.155 NM_001143805
NM_001143806
NM_170732
BDNF


brain-derived neurotrophic factor


chr6_+_143929316 3.150 NM_001100166
NM_014721
PHACTR2

phosphatase and actin regulator 2

chr18_-_46469118 3.121 NM_001190823
SMAD7
SMAD family member 7
chr21_-_39870303 3.078 NM_001136155
NM_182918
ERG

v-ets erythroblastosis virus E26 oncogene homolog (avian)

chr11_+_7618416 3.076 PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr17_-_46688279 3.041 HOXB7
homeobox B7
chr2_+_66662516 2.944 NM_002398
MEIS1
Meis homeobox 1
chr3_-_18480203 2.916 NM_001131010
SATB1
SATB homeobox 1
chr6_+_16143281 2.903 MYLIP
myosin regulatory light chain interacting protein
chr9_-_14398981 2.888 NM_001190738
NFIB
nuclear factor I/B
chr6_+_144612872 2.874 NM_007124
UTRN
utrophin
chr10_+_94594469 2.858 NM_001013848
EXOC6
exocyst complex component 6
chrX_+_135278912 2.850 NM_001159701
NM_001159699
FHL1

four and a half LIM domains 1

chr5_+_59784004 2.814 PART1
prostate androgen-regulated transcript 1 (non-protein coding)
chr1_+_168250277 2.808 NM_005149
TBX19
T-box 19
chr5_+_61874561 2.791 NM_181506
LRRC70
leucine rich repeat containing 70
chr17_-_46688362 2.786 NM_004502
HOXB7
homeobox B7
chr12_-_71031174 2.776 NM_001109754
PTPRB
protein tyrosine phosphatase, receptor type, B
chr4_-_16900028 2.753 LDB2
LIM domain binding 2
chr2_+_132480063 2.749 NM_013310
C2orf27A
chromosome 2 open reading frame 27A
chr6_-_13408368 2.749 NM_001242630
GFOD1
glucose-fructose oxidoreductase domain containing 1
chr12_-_14132920 2.739 NM_000834
GRIN2B
glutamate receptor, ionotropic, N-methyl D-aspartate 2B
chr4_-_16900256 2.730 LDB2
LIM domain binding 2
chrX_+_28605558 2.725 NM_014271
IL1RAPL1
interleukin 1 receptor accessory protein-like 1
chr17_-_46651809 2.718 NM_002146
HOXB3
homeobox B3
chr20_-_45985411 2.705 NM_012408
NM_183047
NM_183048
ZMYND8


zinc finger, MYND-type containing 8


chr2_+_177016112 2.675 NM_014621
HOXD4
homeobox D4
chr13_+_58205788 2.652 NM_001040429
PCDH17
protocadherin 17
chr9_-_13250313 2.616 NM_003829
MPDZ
multiple PDZ domain protein
chr13_-_45010937 2.608 TSC22D1
TSC22 domain family, member 1
chr3_-_114478117 2.601 NM_001164344
NM_001164345
ZBTB20

zinc finger and BTB domain containing 20

chr15_+_96869156 2.562 NM_001145155
NR2F2
nuclear receptor subfamily 2, group F, member 2
chrX_-_117107700 2.560 NM_033495
NM_001168300
KLHL13

kelch-like 13 (Drosophila)

chrX_+_135251454 2.539 NM_001159704
FHL1
four and a half LIM domains 1
chr4_-_101439071 2.470 NM_001159694
NM_016242
EMCN

endomucin

chr18_-_53071225 2.466 NM_001243232
TCF4
transcription factor 4
chr20_-_45927496 2.442 ZMYND8
zinc finger, MYND-type containing 8
chr3_-_137851123 2.393 NM_016161
A4GNT
alpha-1,4-N-acetylglucosaminyltransferase
chr2_-_99279935 2.391 NM_001160154
MGAT4A
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
chr4_+_88529680 2.389 NM_014208
DSPP
dentin sialophosphoprotein
chr4_-_138453628 2.387 NM_019035
PCDH18
protocadherin 18
chr2_+_177016337 2.365


chr3_-_105421044 2.345 CBLB
Cas-Br-M (murine) ecotropic retroviral transforming sequence b
chr11_-_33913835 2.319 NM_005574
LMO2
LIM domain only 2 (rhombotin-like 1)
chr18_-_52988916 2.316 NM_001243234
NM_001243235
TCF4

transcription factor 4

chrX_-_32430370 2.256 NM_004011
NM_004012
DMD

dystrophin

chr5_-_168271852 2.254


chr7_-_86595203 2.227 NM_152748
KIAA1324L
KIAA1324-like
chrX_-_33357725 2.210 NM_000109
DMD
dystrophin
chr5_-_112630557 2.158 NM_002387
MCC
mutated in colorectal cancers
chr10_-_116444374 2.149 NM_001003407
NM_001003408
ABLIM1

actin binding LIM protein 1

chr8_-_93029864 2.144 NM_175636
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr16_-_67517715 2.133 NM_001138
AGRP
agouti related protein homolog (mouse)
chr3_-_18466759 2.113 NM_001195470
NM_002971
SATB1

SATB homeobox 1

chr7_+_102553343 2.108 NM_001031692
NM_005824
LRRC17

leucine rich repeat containing 17

chrX_-_10535476 2.101 NM_001193278
NM_001193279
NM_001193280
NM_001193281
MID1



midline 1 (Opitz/BBB syndrome)



chr17_-_38938785 2.082 NM_181537
KRT27
keratin 27
chr9_-_124989755 2.060 NM_001242334
LHX6
LIM homeobox 6
chr3_+_159557745 2.035 SCHIP1
schwannomin interacting protein 1
chr10_+_83637442 2.019 NM_001165973
NRG3
neuregulin 3
chr1_+_100326765 2.010 NM_000645
AGL
amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase
chr1_+_244214576 1.995 ZNF238
zinc finger protein 238
chr2_+_33359607 1.985 NM_000627
NM_001166264
NM_001166265
NM_001166266
LTBP1



latent transforming growth factor beta binding protein 1



chr4_-_186877413 1.975 SORBS2
sorbin and SH3 domain containing 2
chr11_-_27741192 1.959 NM_001143807
BDNF
brain-derived neurotrophic factor
chr9_-_14314036 1.959 NM_001190737
NM_005596
NFIB

nuclear factor I/B

chr18_+_42260774 1.956 NM_015559
SETBP1
SET binding protein 1
chr12_+_32654976 1.952 NM_139241
FGD4
FYVE, RhoGEF and PH domain containing 4
chrX_-_19817854 1.945 SH3KBP1
SH3-domain kinase binding protein 1
chr18_-_53177999 1.944 NM_001243231
TCF4
transcription factor 4
chr10_-_126716452 1.928 NM_022802
CTBP2
C-terminal binding protein 2
chr7_-_27213873 1.923 NM_018951
HOXA10
homeobox A10
chr4_-_138453564 1.916 PCDH18
protocadherin 18
chr14_+_38678280 1.907 SSTR1
somatostatin receptor 1
chr17_-_1248346 1.903 PAFAH1B1
platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
chr11_-_27723061 1.900 NM_170733
BDNF
brain-derived neurotrophic factor
chrX_-_32173585 1.891 NM_004013
NM_004020
NM_004021
NM_004022
NM_004023
DMD




dystrophin




chr10_+_35464514 1.880 NM_182769
NM_182770
CREM

cAMP responsive element modulator

chr1_-_76397975 1.873 NM_080868
ASB17
ankyrin repeat and SOCS box containing 17
chr12_+_14538232 1.869 ATF7IP
activating transcription factor 7 interacting protein
chr11_+_58390145 1.850 NM_000614
CNTF
ciliary neurotrophic factor
chr6_+_153019029 1.843 NM_025107
MYCT1
myc target 1
chr12_-_50616425 1.841 NM_001113547
LIMA1
LIM domain and actin binding 1
chr20_+_11898536 1.835 NM_014962
BTBD3
BTB (POZ) domain containing 3
chr13_-_48987652 1.822 NM_001162498
LPAR6
lysophosphatidic acid receptor 6
chr4_+_140587086 1.821 MGST2
microsomal glutathione S-transferase 2
chr5_+_42565963 1.819 NM_001242460
NM_001242461
NM_001242462
GHR


growth hormone receptor


chr14_-_92413738 1.818 FBLN5
fibulin 5
chr4_-_186577858 1.816 SORBS2
sorbin and SH3 domain containing 2
chr11_-_71752099 1.809 NUMA1
nuclear mitotic apparatus protein 1
chr9_+_79115548 1.806 NM_001097636
GCNT1
glucosaminyl (N-acetyl) transferase 1, core 2
chr4_+_170581212 1.800 NM_001243374
CLCN3
chloride channel 3
chr3_+_113616317 1.796 NM_001172105
GRAMD1C
GRAM domain containing 1C
chr16_+_53133063 1.766 CHD9
chromodomain helicase DNA binding protein 9
chr5_-_39394423 1.757 DAB2
disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)
chrX_-_18690187 1.753 NM_000330
RS1
retinoschisin 1
chr4_-_186578122 1.744 NM_001145674
NM_001145675
SORBS2

sorbin and SH3 domain containing 2

chr10_-_33623299 1.722 NRP1
neuropilin 1
chr4_-_141075232 1.721 NM_018717
MAML3
mastermind-like 3 (Drosophila)
chr3_+_132318980 1.721 NM_178445
CCRL1
chemokine (C-C motif) receptor-like 1
chr21_-_40033617 1.715 NM_001243432
NM_001136154
NM_004449
ERG


v-ets erythroblastosis virus E26 oncogene homolog (avian)


chr1_-_94586678 1.715 NM_000350
ABCA4
ATP-binding cassette, sub-family A (ABC1), member 4
chr15_+_96876568 1.695 NM_001145157
NR2F2
nuclear receptor subfamily 2, group F, member 2
chr9_+_97521930 1.695 NM_001193329
C9orf3
chromosome 9 open reading frame 3
chr9_-_113100076 1.692 NM_001003936
TXNDC8
thioredoxin domain containing 8 (spermatozoa)
chrX_+_102585113 1.682 NM_152278
TCEAL7
transcription elongation factor A (SII)-like 7
chr2_-_177502658 1.680 LOC375295
uncharacterized LOC375295
chr8_-_17752847 1.679 NM_147203
NM_201553
NM_004467
NM_201552
FGL1



fibrinogen-like 1



chr12_+_80603232 1.679 NM_173591
OTOGL
otogelin-like
chr1_+_244216506 1.678 NM_006352
ZNF238
zinc finger protein 238
chr2_-_198540583 1.678 NM_144629
RFTN2
raftlin family member 2
chr10_+_63808968 1.671 NM_001244638
ARID5B
AT rich interactive domain 5B (MRF1-like)
chr3_-_168864066 1.669 NM_001105077
NM_001163999
NM_005241
MECOM


MDS1 and EVI1 complex locus


chr4_-_159093523 1.665 FAM198B
family with sequence similarity 198, member B
chr5_+_175108463 1.648 NM_022304
HRH2
histamine receptor H2
chr20_+_42574535 1.631 NM_001098798
TOX2
TOX high mobility group box family member 2
chr12_+_79258588 1.624 SYT1
synaptotagmin I
chr5_+_139505519 1.618 NM_001007189
IGIP
IgA-inducing protein homolog (Bos taurus)
chr5_-_90679115 1.609 NM_020801
ARRDC3
arrestin domain containing 3
chr17_-_16097882 1.607 NM_001190438
NM_001190440
NCOR1

nuclear receptor corepressor 1

chr10_-_64576074 1.593 EGR2
early growth response 2
chr8_-_93111915 1.590 NM_001198628
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr4_-_146859960 1.566


chr5_+_95066628 1.558 NM_014899
RHOBTB3
Rho-related BTB domain containing 3
chr8_-_93075190 1.546 NM_004349
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr6_-_32157511 1.539 NM_002586
PBX2
pre-B-cell leukemia homeobox 2
chr10_+_112344076 1.535 SMC3
structural maintenance of chromosomes 3
chr3_-_114343052 1.534 NM_001164347
ZBTB20
zinc finger and BTB domain containing 20
chr6_+_87969619 1.503 ZNF292
zinc finger protein 292
chr4_-_2230957 1.500 NM_181808
POLN
polymerase (DNA directed) nu
chr14_+_70236266 1.496 SRSF5
serine/arginine-rich splicing factor 5
chr2_-_225266710 1.488 NM_001122779
NM_024785
FAM124B

family with sequence similarity 124B

chr18_+_33234532 1.488 NM_020474
GALNT1
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 1 (GalNAc-T1)
chr3_+_148545587 1.488 NM_001871
CPB1
carboxypeptidase B1 (tissue)
chr10_-_64576123 1.478 NM_000399
NM_001136177
NM_001136179
EGR2


early growth response 2


chr17_-_35656691 1.476 NM_198837
NM_198838
ACACA

acetyl-CoA carboxylase alpha

chr1_+_33004771 1.470 NM_001040441
ZBTB8A
zinc finger and BTB domain containing 8A

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.34 6.64e-16 GO:0007275 multicellular organismal development
1.31 1.20e-14 GO:0032502 developmental process
1.36 1.26e-13 GO:0048731 system development
1.32 4.43e-12 GO:0048856 anatomical structure development
1.21 1.23e-09 GO:0032501 multicellular organismal process
1.09 2.31e-07 GO:0009987 cellular process
1.54 5.27e-07 GO:0009891 positive regulation of biosynthetic process
1.54 6.53e-07 GO:0031328 positive regulation of cellular biosynthetic process
1.39 8.24e-07 GO:0007399 nervous system development
1.49 1.06e-06 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.57 1.12e-06 GO:0010557 positive regulation of macromolecule biosynthetic process
1.39 1.61e-06 GO:0009653 anatomical structure morphogenesis
1.33 3.31e-06 GO:0048513 organ development
1.30 9.42e-06 GO:0048523 negative regulation of cellular process
1.12 1.32e-05 GO:0065007 biological regulation
1.56 1.33e-05 GO:0010628 positive regulation of gene expression
1.40 1.47e-05 GO:0009893 positive regulation of metabolic process
1.58 1.65e-05 GO:0045893 positive regulation of transcription, DNA-dependent
1.25 1.96e-05 GO:0048518 positive regulation of biological process
1.75 3.11e-05 GO:0009792 embryo development ending in birth or egg hatching
1.75 3.42e-05 GO:0043009 chordate embryonic development
1.81 3.65e-05 GO:0001501 skeletal system development
1.94 5.29e-05 GO:0003002 regionalization
1.26 1.05e-04 GO:0048519 negative regulation of biological process
1.58 2.09e-04 GO:0045892 negative regulation of transcription, DNA-dependent
1.38 2.11e-04 GO:0031325 positive regulation of cellular metabolic process
1.58 2.17e-04 GO:0051253 negative regulation of RNA metabolic process
1.38 2.39e-04 GO:0010604 positive regulation of macromolecule metabolic process
1.44 3.52e-04 GO:0006351 transcription, DNA-dependent
1.51 3.64e-04 GO:0051254 positive regulation of RNA metabolic process
1.27 4.62e-04 GO:0030154 cell differentiation
1.41 4.85e-04 GO:0032774 RNA biosynthetic process
1.49 6.19e-04 GO:0009890 negative regulation of biosynthetic process
1.46 6.46e-04 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.65 6.50e-04 GO:0000122 negative regulation of transcription from RNA polymerase II promoter
1.60 6.54e-04 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
1.26 7.02e-04 GO:0048869 cellular developmental process
1.12 7.65e-04 GO:0050794 regulation of cellular process
1.48 7.66e-04 GO:0009790 embryo development
1.49 7.71e-04 GO:0031327 negative regulation of cellular biosynthetic process
1.43 8.74e-04 GO:0048699 generation of neurons
1.24 9.78e-04 GO:0048522 positive regulation of cellular process
1.46 9.79e-04 GO:2000026 regulation of multicellular organismal development
1.51 1.07e-03 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.45 1.14e-03 GO:0051173 positive regulation of nitrogen compound metabolic process
1.50 1.20e-03 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
1.11 1.21e-03 GO:0050789 regulation of biological process
1.49 1.33e-03 GO:0010558 negative regulation of macromolecule biosynthetic process
1.51 1.33e-03 GO:0010629 negative regulation of gene expression
1.67 2.24e-03 GO:0007389 pattern specification process
1.99 2.26e-03 GO:0009952 anterior/posterior pattern formation
1.49 2.29e-03 GO:0051172 negative regulation of nitrogen compound metabolic process
1.40 2.30e-03 GO:0022008 neurogenesis
1.23 2.40e-03 GO:0010556 regulation of macromolecule biosynthetic process
2.41 3.55e-03 GO:0048706 embryonic skeletal system development
1.22 7.04e-03 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.31 8.39e-03 GO:0051239 regulation of multicellular organismal process
1.38 8.61e-03 GO:0050793 regulation of developmental process
1.21 9.07e-03 GO:0071842 cellular component organization at cellular level
2.32 9.09e-03 GO:0045637 regulation of myeloid cell differentiation
1.20 9.23e-03 GO:0009889 regulation of biosynthetic process
1.18 1.02e-02 GO:0016043 cellular component organization
1.20 1.29e-02 GO:0031326 regulation of cellular biosynthetic process
1.43 1.31e-02 GO:0045595 regulation of cell differentiation
1.16 1.90e-02 GO:0023052 signaling
1.42 2.02e-02 GO:0030182 neuron differentiation
1.37 2.63e-02 GO:0009888 tissue development
1.53 2.66e-02 GO:0032583 regulation of gene-specific transcription
1.49 2.73e-02 GO:0000904 cell morphogenesis involved in differentiation
1.35 3.02e-02 GO:0010605 negative regulation of macromolecule metabolic process
1.57 3.28e-02 GO:0010551 regulation of gene-specific transcription from RNA polymerase II promoter
1.35 3.41e-02 GO:0031324 negative regulation of cellular metabolic process
1.34 3.59e-02 GO:0009892 negative regulation of metabolic process
1.20 3.78e-02 GO:0010468 regulation of gene expression
2.78 4.10e-02 GO:0045639 positive regulation of myeloid cell differentiation
1.44 4.47e-02 GO:0000902 cell morphogenesis

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.23 9.54e-04 GO:0044459 plasma membrane part
1.46 1.12e-03 GO:0030054 cell junction
1.66 1.36e-02 GO:0016323 basolateral plasma membrane
1.99 1.58e-02 GO:0030055 cell-substrate junction
1.05 1.87e-02 GO:0044424 intracellular part
1.11 2.00e-02 GO:0005634 nucleus
1.75 3.29e-02 GO:0070161 anchoring junction
1.48 4.08e-02 GO:0009986 cell surface
1.77 4.80e-02 GO:0005912 adherens junction

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.48 2.14e-07 GO:0001071 nucleic acid binding transcription factor activity
1.48 2.14e-07 GO:0003700 sequence-specific DNA binding transcription factor activity
1.54 5.36e-06 GO:0043565 sequence-specific DNA binding
1.12 6.00e-06 GO:0005515 protein binding
1.39 9.59e-05 GO:0030528 transcription regulator activity
1.46 6.88e-04 GO:0005509 calcium ion binding
1.52 2.08e-02 GO:0003712 transcription cofactor activity
1.31 2.18e-02 GO:0005102 receptor binding
1.51 2.32e-02 GO:0000988 protein binding transcription factor activity
1.51 2.32e-02 GO:0000989 transcription factor binding transcription factor activity
1.05 3.04e-02 GO:0005488 binding