Motif ID: HSF1,2.p2

Z-value: 1.041


Transcription factors associated with HSF1,2.p2:

Gene SymbolEntrez IDGene Name
HSF1 3297 heat shock transcription factor 1
HSF2 3298 heat shock transcription factor 2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.p-valuePlot
HSF1chr8_+_1455154370.301.4e-01Click!
HSF2chr6_+_122720685-0.232.7e-01Click!


Activity profile for motif HSF1,2.p2.

activity profile for motif HSF1,2.p2


Sorted Z-values histogram for motif HSF1,2.p2

Sorted Z-values for motif HSF1,2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of HSF1,2.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr2_+_102979096 3.049 NM_003855
 IL18R1
interleukin 18 receptor 1
chr9_+_33025302 1.347 DNAJA1
DnaJ (Hsp40) homolog, subfamily A, member 1
chr10_-_116444112 1.333 ABLIM1
actin binding LIM protein 1
chr19_-_14629227 1.301 DNAJB1
DnaJ (Hsp40) homolog, subfamily B, member 1
chr1_+_101185195 1.262 NM_001078
NM_001199834
NM_080682
 VCAM1


vascular cell adhesion molecule 1


chr9_+_33025207 1.240 NM_001539
 DNAJA1
DnaJ (Hsp40) homolog, subfamily A, member 1
chr9_+_33025270 1.222 DNAJA1
DnaJ (Hsp40) homolog, subfamily A, member 1
chr10_-_116444374 1.192 NM_001003407
NM_001003408
 ABLIM1

actin binding LIM protein 1

chr1_-_182354649 1.138 GLUL
glutamate-ammonia ligase
chr6_+_14117486 1.107 NM_001251901
 CD83
CD83 molecule
chr2_+_228678556 1.056 NM_001130046
NM_004591
 CCL20

chemokine (C-C motif) ligand 20

chr17_+_9745847 1.024 GLP2R
glucagon-like peptide 2 receptor
chr17_+_56315786 0.988 NM_001160102
NM_006151
 LPO

lactoperoxidase

chr14_-_75330535 0.935 NM_001080408
NM_001243007
 PROX2

prospero homeobox 2

chr3_+_45067750 0.920 NM_003278
 CLEC3B
C-type lectin domain family 3, member B
chr5_+_118691549 0.910 NM_014350
 TNFAIP8
tumor necrosis factor, alpha-induced protein 8
chr8_+_86099909 0.841 NM_001083589
 E2F5
E2F transcription factor 5, p130-binding
chr19_+_36727325 0.818 ZNF146
zinc finger protein 146
chr5_-_94417185 0.794 MCTP1
multiple C2 domains, transmembrane 1
chr13_+_97874704 0.788 MBNL2
muscleblind-like 2 (Drosophila)

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 32 entries
enrichment   p-value GO term description
8.39 3.06e-03 GO:0060678 dichotomous subdivision of terminal units involved in ureteric bud branching
7.46 1.25e-02 GO:0048880 sensory system development
7.46 1.25e-02 GO:0048892 lateral line nerve development
7.46 1.25e-02 GO:0048895 lateral line nerve glial cell differentiation
7.46 1.25e-02 GO:0048925 lateral line system development
7.46 1.25e-02 GO:0048937 lateral line nerve glial cell development
7.46 1.25e-02 GO:0050935 iridophore differentiation
2.06 1.65e-02 GO:0006457 protein folding
1.85 4.48e-03 GO:0051240 positive regulation of multicellular organismal process
1.83 3.61e-03 GO:0044419 interspecies interaction between organisms
1.61 4.40e-04 GO:2000026 regulation of multicellular organismal development
1.52 3.71e-02 GO:0002682 regulation of immune system process
1.50 1.72e-02 GO:0048584 positive regulation of response to stimulus
1.49 6.75e-03 GO:0051704 multi-organism process
1.47 1.44e-02 GO:0050793 regulation of developmental process
1.47 1.52e-02 GO:0009611 response to wounding
1.45 4.67e-04 GO:0051239 regulation of multicellular organismal process
1.33 3.63e-04 GO:0042221 response to chemical stimulus
1.33 1.50e-03 GO:0048869 cellular developmental process
1.33 2.18e-03 GO:0030154 cell differentiation

Gene overrepresentation in compartment category:

Showing 1 to 8 of 8 entries
enrichment   p-value GO term description
2.15 1.24e-02 GO:0009897 external side of plasma membrane
1.89 2.95e-05 GO:0009986 cell surface
1.53 1.65e-05 GO:0044421 extracellular region part
1.46 1.06e-02 GO:0005615 extracellular space
1.32 3.14e-04 GO:0005576 extracellular region
1.30 5.14e-04 GO:0044459 plasma membrane part
1.18 6.89e-03 GO:0005886 plasma membrane
1.17 7.19e-03 GO:0071944 cell periphery

Gene overrepresentation in function category:

Showing 1 to 3 of 3 entries
enrichment   p-value GO term description
2.63 2.38e-04 GO:0051082 unfolded protein binding
2.49 4.65e-02 GO:0031072 heat shock protein binding
1.15 2.86e-05 GO:0005515 protein binding