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Motif ID: HSF1,2.p2

Z-value: 1.041

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr2_+_102979096	3.049	NM_003855	IL18R1	interleukin 18 receptor 1
chr9_+_33025302	1.347		DNAJA1	DnaJ (Hsp40) homolog, subfamily A, member 1
chr10_-_116444112	1.333		ABLIM1	actin binding LIM protein 1
chr19_-_14629227	1.301		DNAJB1	DnaJ (Hsp40) homolog, subfamily B, member 1
chr1_+_101185195	1.262	NM_001078 NM_001199834 NM_080682	VCAM1	vascular cell adhesion molecule 1
chr9_+_33025207	1.240	NM_001539	DNAJA1	DnaJ (Hsp40) homolog, subfamily A, member 1
chr9_+_33025270	1.222		DNAJA1	DnaJ (Hsp40) homolog, subfamily A, member 1
chr10_-_116444374	1.192	NM_001003407 NM_001003408	ABLIM1	actin binding LIM protein 1
chr1_-_182354649	1.138		GLUL	glutamate-ammonia ligase
chr6_+_14117486	1.107	NM_001251901	CD83	CD83 molecule
chr2_+_228678556	1.056	NM_001130046 NM_004591	CCL20	chemokine (C-C motif) ligand 20
chr17_+_9745847	1.024		GLP2R	glucagon-like peptide 2 receptor
chr17_+_56315786	0.988	NM_001160102 NM_006151	LPO	lactoperoxidase
chr14_-_75330535	0.935	NM_001080408 NM_001243007	PROX2	prospero homeobox 2
chr3_+_45067750	0.920	NM_003278	CLEC3B	C-type lectin domain family 3, member B
chr5_+_118691549	0.910	NM_014350	TNFAIP8	tumor necrosis factor, alpha-induced protein 8
chr8_+_86099909	0.841	NM_001083589	E2F5	E2F transcription factor 5, p130-binding
chr19_+_36727325	0.818		ZNF146	zinc finger protein 146
chr5_-_94417185	0.794		MCTP1	multiple C2 domains, transmembrane 1
chr13_+_97874704	0.788		MBNL2	muscleblind-like 2 (Drosophila)
chr9_-_69202203	0.755	NM_001085476	FOXD4L6	forkhead box D4-like 6
chr1_+_66798095	0.753		PDE4B	phosphodiesterase 4B, cAMP-specific
chr22_-_36556781	0.753	NM_145640	APOL3	apolipoprotein L, 3
chr6_-_143266283	0.746	NM_006734	HIVEP2	human immunodeficiency virus type I enhancer binding protein 2
chr2_-_192711651	0.746		SDPR	serum deprivation response
chr14_+_63671101	0.734	NM_020663	RHOJ	ras homolog gene family, member J
chr19_-_42947050	0.729	NM_198477	CXCL17	chemokine (C-X-C motif) ligand 17
chr2_+_106682111	0.714	NM_032411	C2orf40	chromosome 2 open reading frame 40
chr21_-_35899046	0.687	NM_203418	RCAN1	regulator of calcineurin 1
chr14_-_55369163	0.674	NM_000161 NM_001024024 NM_001024070 NM_001024071	GCH1	GTP cyclohydrolase 1
chr4_-_101439071	0.670	NM_001159694 NM_016242	EMCN	endomucin
chr20_+_31755882	0.662	NM_080574	BPIFA2	BPI fold containing family A, member 2
chr2_-_136875629	0.657	NM_003467	CXCR4	chemokine (C-X-C motif) receptor 4
chr17_-_56494889	0.656		RNF43	ring finger protein 43
chr2_+_169926084	0.651		DHRS9	dehydrogenase/reductase (SDR family) member 9
chr2_+_68872953	0.627	NM_138964	PROKR1	prokineticin receptor 1
chr19_-_14629235	0.624
chr7_+_21468293	0.619
chr17_-_56494930	0.609	NM_017763	RNF43	ring finger protein 43
chr3_-_112359660	0.601		CCDC80	coiled-coil domain containing 80
chr6_+_159309618	0.597	NM_001195032	C6orf99	chromosome 6 open reading frame 99
chr11_+_6897855	0.593	NM_207186	OR10A4	olfactory receptor, family 10, subfamily A, member 4
chr7_+_94024201	0.590		COL1A2	collagen, type I, alpha 2
chr9_+_42717233	0.568	NM_001099279 NM_199244	FOXD4L2 FOXD4L4	forkhead box D4-like 2 forkhead box D4-like 4
chr20_+_44746948	0.542		CD40	CD40 molecule, TNF receptor superfamily member 5
chr7_-_92777657	0.540	NM_152703	SAMD9L	sterile alpha motif domain containing 9-like
chr10_-_75410778	0.536	NM_024875	SYNPO2L	synaptopodin 2-like
chr14_+_24540742	0.535	NM_006032	CPNE6	copine VI (neuronal)
chr2_-_188419049	0.528		TFPI	tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
chr16_+_3115638	0.523	NM_001012634	IL32	interleukin 32
chr1_-_112046742	0.522	NM_000677 NM_020683	ADORA3	adenosine A3 receptor
chr6_+_106534188	0.520	NM_001198	PRDM1	PR domain containing 1, with ZNF domain
chr5_-_94417544	0.513	NM_001002796	MCTP1	multiple C2 domains, transmembrane 1
chr4_+_71263598	0.512	NM_021225	PROL1	proline rich, lacrimal 1
chr3_-_112358510	0.505		CCDC80	coiled-coil domain containing 80
chr3_-_112358758	0.502		CCDC80	coiled-coil domain containing 80
chr19_+_41509825	0.501		CYP2B6	cytochrome P450, family 2, subfamily B, polypeptide 6
chr16_+_3115641	0.497	NM_001012632 NM_001012636	IL32	interleukin 32
chr7_+_30960914	0.494	NM_001185060 NM_001185061 NM_001185062	AQP1	aquaporin 1 (Colton blood group)
chr1_-_32827843	0.493	NM_001167676	LOC100128071	uncharacterized LOC100128071
chr3_-_151102536	0.491	NM_022788	P2RY12	purinergic receptor P2Y, G-protein coupled, 12
chr1_+_168195257	0.483		SFT2D2	SFT2 domain containing 2
chrX_+_135278912	0.480	NM_001159701 NM_001159699	FHL1	four and a half LIM domains 1
chr1_+_168195248	0.478	NM_199344	SFT2D2	SFT2 domain containing 2
chr16_+_3115312	0.478	NM_001012631 NM_001012633 NM_001012718 NM_004221	IL32	interleukin 32
chr12_+_10460416	0.475	NM_002262 NM_007334	KLRD1	killer cell lectin-like receptor subfamily D, member 1
chr1_+_32827797	0.471	NM_052841	TSSK3	testis-specific serine kinase 3
chr16_+_3115611	0.470	NM_001012635	IL32	interleukin 32
chr1_-_42776760	0.470
chr12_+_54891539	0.464		NCKAP1L	NCK-associated protein 1-like
chr3_-_112359863	0.463		CCDC80	coiled-coil domain containing 80
chr13_+_97874540	0.462	NM_144778 NM_207304	MBNL2	muscleblind-like 2 (Drosophila)
chr3_+_30648372	0.454		TGFBR2	transforming growth factor, beta receptor II (70/80kDa)
chr2_+_28615771	0.450	NM_005253	FOSL2	FOS-like antigen 2
chr18_-_500583	0.450	NM_130386	COLEC12	collectin sub-family member 12
chr3_-_112359962	0.448	NM_199511 NM_199512	CCDC80	coiled-coil domain containing 80
chr10_+_35464514	0.447	NM_182769 NM_182770	CREM	cAMP responsive element modulator
chr6_+_138188352	0.444	NM_006290	TNFAIP3	tumor necrosis factor, alpha-induced protein 3
chr7_+_134832765	0.444	NM_018295	TMEM140	transmembrane protein 140
chr1_-_55089068	0.442	NM_176782	FAM151A	family with sequence similarity 151, member A
chr8_-_142238672	0.441	NM_001080431	SLC45A4	solute carrier family 45, member 4
chr16_+_3115639	0.432		IL32	interleukin 32
chr22_+_45705965	0.430		FAM118A	family with sequence similarity 118, member A
chrX_+_135230736	0.427	NM_001159700	FHL1	four and a half LIM domains 1
chr8_-_82395401	0.423	NM_001442	FABP4	fatty acid binding protein 4, adipocyte
chr5_+_54320083	0.423	NM_002104	GZMK	granzyme K (granzyme 3; tryptase II)
chr1_-_231175971	0.423	NM_198552	FAM89A	family with sequence similarity 89, member A
chr3_-_9290592	0.421		SRGAP3	SLIT-ROBO Rho GTPase activating protein 3
chr11_-_121986800	0.421	NM_001001786	BLID	BH3-like motif containing, cell death inducer
chr11_+_64323089	0.418	NM_018484	SLC22A11	solute carrier family 22 (organic anion/urate transporter), member 11
chr9_-_91793375	0.417		SHC3	SHC (Src homology 2 domain containing) transforming protein 3
chr6_+_126240369	0.416	NM_001199622	NCOA7	nuclear receptor coactivator 7
chr11_-_71791734	0.413		NUMA1	nuclear mitotic apparatus protein 1
chr5_+_139060058	0.408		CXXC5	CXXC finger protein 5
chr3_+_122334461	0.406	NM_152615	PARP15	poly (ADP-ribose) polymerase family, member 15
chr20_+_31870940	0.404	NM_033197	BPIFB1	BPI fold containing family B, member 1
chr7_-_14880954	0.402	NM_004080 NM_145695	DGKB	diacylglycerol kinase, beta 90kDa
chr3_+_182971213	0.399		B3GNT5	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5
chr1_-_175712669	0.396	NM_003285	TNR	tenascin R (restrictin, janusin)
chr12_+_51318743	0.394		METTL7A	methyltransferase like 7A
chr22_+_31608284	0.394		LIMK2	LIM domain kinase 2
chr18_+_57567191	0.386	NM_021127	PMAIP1	phorbol-12-myristate-13-acetate-induced protein 1
chr7_-_75443026	0.385	NM_002991	CCL24	chemokine (C-C motif) ligand 24
chr2_+_169937616	0.382	NM_001142271	DHRS9	dehydrogenase/reductase (SDR family) member 9
chr2_+_85766286	0.381		MAT2A	methionine adenosyltransferase II, alpha
chr3_-_122233764	0.381		KPNA1	karyopherin alpha 1 (importin alpha 5)
chr22_-_27014037	0.379		CRYBB1	crystallin, beta B1
chr1_+_12834983	0.373	NM_001080830	PRAMEF12	PRAME family member 12
chr2_+_210444154	0.372		MAP2	microtubule-associated protein 2
chr5_+_139060186	0.369		CXXC5	CXXC finger protein 5
chr16_-_89831445	0.365		FANCA	Fanconi anemia, complementation group A
chr19_-_54692132	0.364		MBOAT7	membrane bound O-acyltransferase domain containing 7
chr22_-_27013959	0.364	NM_001887	CRYBB1	crystallin, beta B1
chrX_-_8700132	0.361		KAL1	Kallmann syndrome 1 sequence
chr22_+_31608145	0.360		LIMK2	LIM domain kinase 2
chr4_-_74904329	0.357	NM_002090	CXCL3	chemokine (C-X-C motif) ligand 3
chr7_+_75931829	0.357	NM_001540	HSPB1	heat shock 27kDa protein 1
chr6_-_76203256	0.356	NM_015687	FILIP1	filamin A interacting protein 1
chr16_-_75498497	0.356		TMEM170A	transmembrane protein 170A
chr1_+_47603083	0.355	NM_001010969	CYP4A22	cytochrome P450, family 4, subfamily A, polypeptide 22
chr14_+_64680858	0.353	NM_182913	SYNE2	spectrin repeat containing, nuclear envelope 2
chr16_+_31494438	0.351	NM_003041	SLC5A2	solute carrier family 5 (sodium/glucose cotransporter), member 2
chr1_+_114522029	0.348	NM_020190	OLFML3	olfactomedin-like 3
chr13_+_111855406	0.348		ARHGEF7	Rho guanine nucleotide exchange factor (GEF) 7
chr4_+_41614933	0.343		LIMCH1	LIM and calponin homology domains 1
chr6_-_56112315	0.343	NM_030820	COL21A1	collagen, type XXI, alpha 1
chr5_+_79330990	0.342	NM_003248	THBS4	thrombospondin 4
chr12_+_51318515	0.342	NM_014033	METTL7A	methyltransferase like 7A
chr7_+_75931991	0.341		HSPB1	heat shock 27kDa protein 1
chr20_+_43343523	0.338		WISP2	WNT1 inducible signaling pathway protein 2
chr2_+_28615668	0.338		FOSL2	FOS-like antigen 2
chr10_-_45474210	0.335	NM_007021	C10orf10	chromosome 10 open reading frame 10
chr20_+_44746889	0.333	NM_001250 NM_152854	CD40	CD40 molecule, TNF receptor superfamily member 5
chr10_+_75673346	0.330		PLAU	plasminogen activator, urokinase
chr2_+_28616346	0.330		FOSL2	FOS-like antigen 2
chr1_-_1149495	0.329	NM_003327	TNFRSF4	tumor necrosis factor receptor superfamily, member 4
chr9_-_70178814	0.327	NM_001126334	FOXD4L5	forkhead box D4-like 5
chrX_+_80457559	0.327		SH3BGRL	SH3 domain binding glutamic acid-rich protein like
chr20_-_34243118	0.327		RBM12	RNA binding motif protein 12
chr2_+_152214105	0.324	NM_007115	TNFAIP6	tumor necrosis factor, alpha-induced protein 6
chr17_+_18855477	0.324	NM_001042450 NM_152351	SLC5A10	solute carrier family 5 (sodium/glucose cotransporter), member 10
chr18_-_29340698	0.324	NM_001034172	MCART2	mitochondrial carrier triple repeat 2
chr10_-_98119058	0.324	NM_001040102 NM_001040103 NM_033207	OPALIN	oligodendrocytic myelin paranodal and inner loop protein
chr1_-_12677347	0.323	NM_004753	DHRS3	dehydrogenase/reductase (SDR family) member 3
chr10_+_95848811	0.321	NM_001165979	PLCE1	phospholipase C, epsilon 1
chr17_-_76573475	0.320	NM_173628	DNAH17	dynein, axonemal, heavy chain 17
chr19_-_14629160	0.319	NM_006145	DNAJB1	DnaJ (Hsp40) homolog, subfamily B, member 1
chr9_+_70917782	0.319	NM_199135	FOXD4L3 FOXD4L6	forkhead box D4-like 3 forkhead box D4-like 6
chr11_-_33913835	0.318	NM_005574	LMO2	LIM domain only 2 (rhombotin-like 1)
chr1_+_168195241	0.317		SFT2D2	SFT2 domain containing 2
chr11_-_34535302	0.316	NM_001243080 NM_001422	ELF5	E74-like factor 5 (ets domain transcription factor)
chr12_-_123011457	0.315	NM_023012	RSRC2	arginine/serine-rich coiled-coil 2
chr11_-_128391888	0.313		ETS1	v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)
chr7_+_150264457	0.311	NM_018326	GIMAP4	GTPase, IMAP family member 4
chr1_-_173638970	0.310	NM_198493	ANKRD45	ankyrin repeat domain 45
chr6_+_126102278	0.310	NM_001199619 NM_001199620	NCOA7	nuclear receptor coactivator 7
chr3_+_114012832	0.308	NM_173799	TIGIT	T cell immunoreceptor with Ig and ITIM domains
chr11_-_128457452	0.308	NM_001143820	ETS1	v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)
chr5_+_140797243	0.307	NM_018927	PCDHGB7	protocadherin gamma subfamily B, 7
chrX_-_107225588	0.302	NM_031273	TEX13B	testis expressed 13B
chr2_-_24583291	0.301	NM_006277 NM_019595 NM_147152	ITSN2	intersectin 2
chr3_-_133648517	0.297	NM_025041	C3orf36	chromosome 3 open reading frame 36
chr12_-_9268440	0.295		A2M	alpha-2-macroglobulin
chrX_-_15683153	0.294	NM_020665	TMEM27	transmembrane protein 27
chr5_-_42175355	0.294
chr17_-_39093671	0.293	NM_015515	KRT23	keratin 23 (histone deacetylase inducible)
chr12_+_11802905	0.293		ETV6	ets variant 6
chr5_-_32313069	0.293	NM_001040446	MTMR12	myotubularin related protein 12
chr14_+_103800678	0.292		EIF5	eukaryotic translation initiation factor 5
chr14_-_25103365	0.291	NM_004131	GZMB	granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
chr9_-_73736513	0.290	NM_001007471	TRPM3	transient receptor potential cation channel, subfamily M, member 3
chr3_+_46539484	0.290	NM_031440	RTP3	receptor (chemosensory) transporter protein 3
chr19_+_7049349	0.290	NM_144614	MBD3L2	methyl-CpG binding domain protein 3-like 2
chr4_+_1953831	0.286		WHSC1	Wolf-Hirschhorn syndrome candidate 1
chr9_-_118416	0.285	NM_207305	FOXD4	forkhead box D4
chr11_-_118084073	0.285	NM_153206	AMICA1	adhesion molecule, interacts with CXADR antigen 1
chr4_-_74964836	0.284		CXCL2	chemokine (C-X-C motif) ligand 2
chr9_-_75567915	0.284		ALDH1A1	aldehyde dehydrogenase 1 family, member A1
chr7_+_114055171	0.283		FOXP2	forkhead box P2
chr6_+_31783280	0.283	NM_005345	HSPA1A	heat shock 70kDa protein 1A
chr6_-_43595079	0.283		GTPBP2	GTP binding protein 2
chr1_+_45274153	0.282	NM_001136537	BTBD19	BTB (POZ) domain containing 19
chr19_+_36726883	0.281		ZNF146	zinc finger protein 146
chr6_-_155635562	0.281		TFB1M	transcription factor B1, mitochondrial
chr8_+_70378858	0.280	NM_001128204 NM_015170	SULF1	sulfatase 1
chr1_-_94375028	0.277		GCLM	glutamate-cysteine ligase, modifier subunit
chr13_+_97928414	0.274		MBNL2	muscleblind-like 2 (Drosophila)
chr1_-_182369750	0.272	NM_172000	TEDDM1	transmembrane epididymal protein 1
chr6_+_31783314	0.272		HSPA1A HSPA1B	heat shock 70kDa protein 1A heat shock 70kDa protein 1B
chr6_-_32339648	0.271	NM_006781	C6orf10	chromosome 6 open reading frame 10
chr11_+_120107348	0.270	NM_001244682	POU2F3	POU class 2 homeobox 3
chr14_+_103800548	0.270		EIF5	eukaryotic translation initiation factor 5
chr13_-_41556188	0.269		ELF1	E74-like factor 1 (ets domain transcription factor)
chr11_-_59436366	0.268		PATL1	protein associated with topoisomerase II homolog 1 (yeast)
chr6_-_53013581	0.263	NM_003643	GCM1	glial cells missing homolog 1 (Drosophila)
chr7_+_130020289	0.263	NM_001868	CPA1	carboxypeptidase A1 (pancreatic)
chr19_-_4559713	0.261	NM_032108	SEMA6B	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B
chr17_+_73663398	0.260	NM_013260	SAP30BP	SAP30 binding protein
chr20_+_32848170	0.259	NM_001672	ASIP	agouti signaling protein
chr13_+_46276445	0.258	NM_152719	SPERT	spermatid associated

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.33	3.63e-04	GO:0042221	response to chemical stimulus
1.28	4.22e-04	GO:0048731	system development
1.61	4.40e-04	GO:2000026	regulation of multicellular organismal development
1.45	4.67e-04	GO:0051239	regulation of multicellular organismal process
1.26	1.20e-03	GO:0048856	anatomical structure development
1.33	1.50e-03	GO:0048869	cellular developmental process
1.08	1.76e-03	GO:0009987	cellular process
1.33	2.18e-03	GO:0030154	cell differentiation
1.24	2.19e-03	GO:0007275	multicellular organismal development
1.22	2.45e-03	GO:0032502	developmental process
8.39	3.06e-03	GO:0060678	dichotomous subdivision of terminal units involved in ureteric bud branching
1.83	3.61e-03	GO:0044419	interspecies interaction between organisms
1.27	3.65e-03	GO:0048518	positive regulation of biological process
1.85	4.48e-03	GO:0051240	positive regulation of multicellular organismal process
1.12	4.49e-03	GO:0065007	biological regulation
1.30	4.77e-03	GO:0065008	regulation of biological quality
1.49	6.75e-03	GO:0051704	multi-organism process
1.17	8.96e-03	GO:0032501	multicellular organismal process
7.46	1.25e-02	GO:0048880	sensory system development
7.46	1.25e-02	GO:0048892	lateral line nerve development
7.46	1.25e-02	GO:0048895	lateral line nerve glial cell differentiation
7.46	1.25e-02	GO:0048925	lateral line system development
7.46	1.25e-02	GO:0048937	lateral line nerve glial cell development
7.46	1.25e-02	GO:0050935	iridophore differentiation
1.12	1.28e-02	GO:0050789	regulation of biological process
1.47	1.44e-02	GO:0050793	regulation of developmental process
1.47	1.52e-02	GO:0009611	response to wounding
2.06	1.65e-02	GO:0006457	protein folding
1.50	1.72e-02	GO:0048584	positive regulation of response to stimulus
1.27	1.95e-02	GO:0006950	response to stress
1.52	3.71e-02	GO:0002682	regulation of immune system process
1.19	4.20e-02	GO:0023052	signaling

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.53	1.65e-05	GO:0044421	extracellular region part
1.89	2.95e-05	GO:0009986	cell surface
1.32	3.14e-04	GO:0005576	extracellular region
1.30	5.14e-04	GO:0044459	plasma membrane part
1.18	6.89e-03	GO:0005886	plasma membrane
1.17	7.19e-03	GO:0071944	cell periphery
1.46	1.06e-02	GO:0005615	extracellular space
2.15	1.24e-02	GO:0009897	external side of plasma membrane

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.15	2.86e-05	GO:0005515	protein binding
2.63	2.38e-04	GO:0051082	unfolded protein binding
2.49	4.65e-02	GO:0031072	heat shock protein binding