Motif ID: JUN.p2

Z-value: 1.088


Transcription factors associated with JUN.p2:

Gene SymbolEntrez IDGene Name
JUN 3725 jun oncogene
JUNB 3726 jun B proto-oncogene
JUND 3727 jun D proto-oncogene

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.p-valuePlot
JUNBchr19_+_129022950.592.0e-03Click!
JUNDchr19_-_183920480.519.1e-03Click!
JUNchr1_-_59248287-0.048.6e-01Click!


Activity profile for motif JUN.p2.

activity profile for motif JUN.p2


Sorted Z-values histogram for motif JUN.p2

Sorted Z-values for motif JUN.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of JUN.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr21_-_44846927 5.622 NM_173354
SIK1
salt-inducible kinase 1
chr2_+_228678556 5.183 NM_001130046
NM_004591
CCL20

chemokine (C-C motif) ligand 20

chr19_+_45971249 4.335 NM_001114171
NM_006732
FOSB

FBJ murine osteosarcoma viral oncogene homolog B

chr1_-_169703178 4.040 NM_000450
SELE
selectin E
chr19_+_45504686 3.720 NM_006509
RELB
v-rel reticuloendotheliosis viral oncogene homolog B
chr8_-_95274540 3.601 NM_005261
NM_181702
GEM

GTP binding protein overexpressed in skeletal muscle

chr19_+_49375677 3.529 PPP1R15A
protein phosphatase 1, regulatory subunit 15A
chr19_+_49375638 3.511 NM_014330
PPP1R15A
protein phosphatase 1, regulatory subunit 15A
chr19_+_49375679 3.457 PPP1R15A
protein phosphatase 1, regulatory subunit 15A
chr9_-_123688352 3.377 TRAF1
TNF receptor-associated factor 1
chr7_+_28448970 3.160 LOC401317
uncharacterized LOC401317
chr1_+_212782103 3.121 ATF3
activating transcription factor 3
chr8_+_23386386 3.067 SLC25A37
solute carrier family 25, member 37
chr18_+_61554938 3.021 NM_001143818
NM_002575
SERPINB2

serpin peptidase inhibitor, clade B (ovalbumin), member 2

chr2_+_28615771 2.687 NM_005253
FOSL2
FOS-like antigen 2
chr3_-_187463474 2.637 NM_001706
BCL6
B-cell CLL/lymphoma 6
chr2_-_157189040 2.630 NM_006186
NR4A2
nuclear receptor subfamily 4, group A, member 2
chr11_+_6226797 2.548 NM_173525
C11orf42
chromosome 11 open reading frame 42
chr2_+_28615695 2.495 FOSL2
FOS-like antigen 2
chr7_+_44646197 2.464 OGDH
oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
chr7_+_44646189 2.449 OGDH
oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
chr7_+_44646168 2.424 OGDH
oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
chr21_-_35899046 2.386 NM_203418
RCAN1
regulator of calcineurin 1
chr1_+_212738675 2.328 NM_001030287
ATF3
activating transcription factor 3
chr11_-_1593149 2.323 NM_004420
DUSP8
dual specificity phosphatase 8
chr2_-_28113954 2.203 LOC100302650
uncharacterized LOC100302650
chr8_-_95274520 2.193 GEM
GTP binding protein overexpressed in skeletal muscle
chr18_+_57567191 2.078 NM_021127
PMAIP1
phorbol-12-myristate-13-acetate-induced protein 1
chr16_+_86544104 2.047 NM_001451
FOXF1
forkhead box F1
chr22_+_38597938 1.971 NM_001161572
NM_001161574
NM_012323
MAFF


v-maf musculoaponeurotic fibrosarcoma oncogene homolog F (avian)


chr2_+_28615668 1.915 FOSL2
FOS-like antigen 2
chr19_+_36024313 1.888 NM_014364
GAPDHS
glyceraldehyde-3-phosphate dehydrogenase, spermatogenic
chr21_-_43430448 1.860 NM_001098402
NM_001098403
NM_020727
ZNF295


zinc finger protein 295


chr4_-_111544206 1.813 NM_000325
PITX2
paired-like homeodomain 2
chr11_+_73087396 1.795 NM_152222
RELT
RELT tumor necrosis factor receptor
chr19_+_50979788 1.754 C19orf63
chromosome 19 open reading frame 63
chr4_+_103422479 1.684 NM_001165412
NM_003998
NFKB1

nuclear factor of kappa light polypeptide gene enhancer in B-cells 1

chr8_+_23386468 1.635 SLC25A37
solute carrier family 25, member 37
chr1_-_16482426 1.633 NM_004431
EPHA2
EPH receptor A2
chr3_-_187463227 1.627 BCL6
B-cell CLL/lymphoma 6
chr19_+_50979656 1.620 NM_175063
NM_206538
C19orf63

chromosome 19 open reading frame 63

chr8_+_23386362 1.613 NM_016612
SLC25A37
solute carrier family 25, member 37
chr8_+_90770201 1.593 RIPK2
receptor-interacting serine-threonine kinase 2
chr22_+_38598065 1.588 MAFF
v-maf musculoaponeurotic fibrosarcoma oncogene homolog F (avian)
chr7_+_44646220 1.582 OGDH
oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
chr6_-_37225360 1.536 NM_145316
TMEM217
transmembrane protein 217
chr3_+_11267666 1.503 NM_001098211
HRH1
histamine receptor H1
chr2_+_152214105 1.462 NM_007115
TNFAIP6
tumor necrosis factor, alpha-induced protein 6
chr11_-_64647136 1.382 EHD1
EH-domain containing 1
chr19_+_16187266 1.376 TPM4
tropomyosin 4
chr11_+_43963809 1.314 NM_001145033
C11orf96
chromosome 11 open reading frame 96
chr19_+_16187306 1.252 TPM4
tropomyosin 4
chr19_+_49109999 1.226 NM_133498
SPACA4
sperm acrosome associated 4
chr9_+_34989637 1.224 NM_001135004
NM_012266
DNAJB5

DnaJ (Hsp40) homolog, subfamily B, member 5

chr7_+_5632435 1.223 NM_003088
FSCN1
fascin homolog 1, actin-bundling protein (Strongylocentrotus purpuratus)
chr15_+_76629101 1.197 NM_145805
ISL2
ISL LIM homeobox 2
chr10_+_104154228 1.181 NM_001077493
NM_001077494
NFKB2

nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)

chr9_+_34990266 1.172 NM_001135005
DNAJB5
DnaJ (Hsp40) homolog, subfamily B, member 5
chr6_-_29595746 1.169 GABBR1
gamma-aminobutyric acid (GABA) B receptor, 1
chr7_+_128312345 1.157 NM_001012454
NM_001128926
FAM71F2

family with sequence similarity 71, member F2

chr5_-_95297597 1.150 NM_012081
ELL2
elongation factor, RNA polymerase II, 2
chr1_+_212781969 1.142 NM_001040619
NM_001206484
NM_001206488
NM_001674
ATF3



activating transcription factor 3



chr7_+_5632453 1.134 FSCN1
fascin homolog 1, actin-bundling protein (Strongylocentrotus purpuratus)
chr3_+_150125983 1.131 TSC22D2
TSC22 domain family, member 2
chr15_+_81293286 1.125 NM_022566
MESDC1
mesoderm development candidate 1
chr10_-_106093662 1.087 NM_033397
ITPRIP
inositol 1,4,5-trisphosphate receptor interacting protein
chr4_+_103422553 1.087 NFKB1
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
chr1_-_151689246 1.074 NM_007185
CELF3
CUGBP, Elav-like family member 3
chr1_+_203274646 1.074 NM_006763
BTG2
BTG family, member 2
chr5_+_113698015 1.065 NM_021614
KCNN2
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2
chr19_+_17666381 1.061 GLT25D1
glycosyltransferase 25 domain containing 1
chr9_+_130860769 1.045 SLC25A25
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25
chr18_+_23806385 1.033 NM_005640
TAF4B
TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa
chr18_+_77155927 1.028 NFATC1
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
chr9_+_102584136 1.018 NM_006981
NM_173199
NM_173200
NR4A3


nuclear receptor subfamily 4, group A, member 3


chr1_-_221915458 1.011 NM_007207
NM_144729
DUSP10

dual specificity phosphatase 10

chr19_+_16187315 0.992 TPM4
tropomyosin 4
chr2_+_97001506 0.986 NCAPH
non-SMC condensin I complex, subunit H
chr1_+_16010816 0.979 NM_015164
PLEKHM2
pleckstrin homology domain containing, family M (with RUN domain) member 2
chr11_+_73087670 0.979 NM_032871
RELT
RELT tumor necrosis factor receptor
chr1_+_16010838 0.971 PLEKHM2
pleckstrin homology domain containing, family M (with RUN domain) member 2
chr9_-_73029539 0.969 NM_001206
KLF9
Kruppel-like factor 9
chr19_+_8455243 0.967 RAB11B
RAB11B, member RAS oncogene family
chr7_+_112090463 0.956 NM_001550
IFRD1
interferon-related developmental regulator 1
chr1_-_221915393 0.950 DUSP10
dual specificity phosphatase 10
chr18_+_77439798 0.931 NM_004715
NM_048368
CTDP1

CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1

chr8_-_27115935 0.928 STMN4
stathmin-like 4
chr19_+_8455265 0.926 RAB11B
RAB11B, member RAS oncogene family
chr19_-_47734215 0.918 NM_014417
BBC3
BCL2 binding component 3
chr8_+_90769974 0.915 NM_003821
RIPK2
receptor-interacting serine-threonine kinase 2
chr18_+_77439843 0.914 CTDP1
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
chr1_-_221915426 0.900 DUSP10
dual specificity phosphatase 10
chr8_-_22550708 0.895 NM_004430
EGR3
early growth response 3
chr2_+_219745243 0.884 NM_025216
WNT10A
wingless-type MMTV integration site family, member 10A
chr11_-_8832189 0.868 NM_213618
ST5
suppression of tumorigenicity 5
chr19_-_48018163 0.866 NAPA
N-ethylmaleimide-sensitive factor attachment protein, alpha
chr10_-_106098161 0.860 ITPRIP
inositol 1,4,5-trisphosphate receptor interacting protein
chr1_-_204380903 0.839 NM_032833
PPP1R15B
protein phosphatase 1, regulatory subunit 15B
chr8_-_27115897 0.833 NM_030795
STMN4
stathmin-like 4
chr20_+_33292117 0.824 NM_021202
TP53INP2
tumor protein p53 inducible nuclear protein 2
chr15_-_74988325 0.820 EDC3
enhancer of mRNA decapping 3 homolog (S. cerevisiae)
chr19_+_36119934 0.811 RBM42
RNA binding motif protein 42
chr12_+_100660846 0.809 SCYL2
SCY1-like 2 (S. cerevisiae)
chr1_+_45266035 0.809 NM_004073
PLK3
polo-like kinase 3
chr2_-_73520448 0.808 NM_001965
EGR4
early growth response 4
chr8_+_126442557 0.808 NM_025195
TRIB1
tribbles homolog 1 (Drosophila)
chr17_-_8055684 0.800 NM_002616
PER1
period homolog 1 (Drosophila)
chr12_+_100661158 0.789 SCYL2
SCY1-like 2 (S. cerevisiae)
chr4_+_103422730 0.788 NFKB1
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
chr13_+_111855406 0.786 ARHGEF7
Rho guanine nucleotide exchange factor (GEF) 7
chr16_+_31119730 0.780 BCKDK
branched chain ketoacid dehydrogenase kinase
chr18_+_77155966 0.780 NFATC1
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
chr6_-_3157696 0.776 NM_001069
TUBB2A
tubulin, beta 2A class IIa
chr19_+_18723666 0.771 NM_012109
TMEM59L
transmembrane protein 59-like
chr9_+_130860816 0.765 NM_052901
NM_001006643
SLC25A25

solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25

chr16_+_31119748 0.760 BCKDK
branched chain ketoacid dehydrogenase kinase
chr19_+_17666457 0.760 GLT25D1
glycosyltransferase 25 domain containing 1
chr3_-_156877882 0.755 CCNL1
cyclin L1
chr17_-_8151353 0.744 CTC1
CTS telomere maintenance complex component 1
chr12_+_132629014 0.740 NOC4L
nucleolar complex associated 4 homolog (S. cerevisiae)
chr10_-_3827205 0.736 KLF6
Kruppel-like factor 6
chr3_-_50374875 0.726 NM_170713
RASSF1
Ras association (RalGDS/AF-6) domain family member 1
chr19_-_7553867 0.717 NM_080662
PEX11G
peroxisomal biogenesis factor 11 gamma
chr10_+_35484054 0.716 NM_182717
NM_182718
NM_182719
NM_182720
CREM



cAMP responsive element modulator



chr6_-_34664587 0.709 NM_022758
NM_024294
C6orf106

chromosome 6 open reading frame 106

chr9_-_140353785 0.704 NM_001130969
NM_001130970
NM_001130971
NM_001178064
NM_015537
NELF




nasal embryonic LHRH factor




chr19_+_45349584 0.700 PVRL2
poliovirus receptor-related 2 (herpesvirus entry mediator B)
chrX_+_48398162 0.699 TBC1D25
TBC1 domain family, member 25
chr11_+_102217915 0.698 BIRC2
baculoviral IAP repeat containing 2
chr19_-_10341947 0.697 NM_004230
S1PR2
sphingosine-1-phosphate receptor 2
chr1_+_45265896 0.693 PLK3
polo-like kinase 3
chr6_-_3227776 0.690 NM_178012
TUBB2B
tubulin, beta 2B class IIb
chr8_+_40010986 0.689 NM_020130
C8orf4
chromosome 8 open reading frame 4
chr19_-_48018277 0.685 NAPA
N-ethylmaleimide-sensitive factor attachment protein, alpha
chr9_+_111624545 0.682 NM_006687
ACTL7A
actin-like 7A
chr8_-_103876390 0.679 NM_015878
NM_148174
AZIN1

antizyme inhibitor 1

chr14_-_69259654 0.673 ZFP36L1
zinc finger protein 36, C3H type-like 1
chr3_+_186739643 0.666 NM_003032
ST6GAL1
ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
chr20_+_58179601 0.665 NM_080672
PHACTR3
phosphatase and actin regulator 3
chr7_+_44646120 0.664 NM_001003941
NM_001165036
NM_002541
OGDH


oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)


chr17_+_26662547 0.655 NM_021137
TNFAIP1
tumor necrosis factor, alpha-induced protein 1 (endothelial)
chr19_+_13056656 0.651 RAD23A
RAD23 homolog A (S. cerevisiae)
chr4_+_103422822 0.649 NFKB1
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
chr7_+_143078457 0.646 ZYX
zyxin
chr19_-_10514242 0.644 NM_007065
CDC37
cell division cycle 37 homolog (S. cerevisiae)
chr5_-_112770537 0.643 NM_032028
TSSK1B
testis-specific serine kinase 1B
chr19_+_16187047 0.642 NM_003290
TPM4
tropomyosin 4
chr4_-_111558150 0.639 PITX2
paired-like homeodomain 2
chr11_-_69519105 0.638 NM_005117
FGF19
fibroblast growth factor 19
chr9_+_130830595 0.637 SLC25A25
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25
chr19_+_39899749 0.637


chr7_+_143078608 0.636 ZYX
zyxin
chr8_-_103876345 0.633 AZIN1
antizyme inhibitor 1
chr2_-_64881040 0.631 NM_014755
SERTAD2
SERTA domain containing 2
chr5_-_95297424 0.630 ELL2
elongation factor, RNA polymerase II, 2
chr7_-_45026204 0.626 SNHG15
small nucleolar RNA host gene 15 (non-protein coding)
chr2_-_74601653 0.624 NM_001135041
NM_023019
DCTN1

dynactin 1

chr3_-_50374795 0.623 RASSF1
Ras association (RalGDS/AF-6) domain family member 1
chr7_+_143078399 0.616 ZYX
zyxin
chr6_+_43211221 0.615 NM_032538
TTBK1
tau tubulin kinase 1
chr9_+_130830447 0.613 NM_001006641
SLC25A25
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25
chr9_-_117444368 0.613 NM_001199233
LOC100505478
uncharacterized LOC100505478
chr19_+_17666502 0.612 NM_024656
GLT25D1
glycosyltransferase 25 domain containing 1
chr16_+_67694795 0.610 NM_001037281
NM_016948
PARD6A

par-6 partitioning defective 6 homolog alpha (C. elegans)

chr12_-_49504612 0.610 LMBR1L
limb region 1 homolog (mouse)-like
chr7_+_143078444 0.605 ZYX
zyxin
chr18_+_56887389 0.604 NM_001012512
NM_001012513
NM_002091
GRP


gastrin-releasing peptide


chr15_-_70390229 0.604 NM_001105192
NM_005078
NM_020908
TLE3


transducin-like enhancer of split 3 (E(sp1) homolog, Drosophila)


chr19_-_18392436 0.601 JUND
jun D proto-oncogene
chr7_+_143078447 0.599 ZYX
zyxin
chr10_+_27444296 0.597 MASTL
microtubule associated serine/threonine kinase-like
chr7_+_143078395 0.597 ZYX
zyxin
chr20_+_30697512 0.596 TM9SF4
transmembrane 9 superfamily protein member 4
chr5_-_172198160 0.596 NM_004417
DUSP1
dual specificity phosphatase 1
chr6_-_134496833 0.595 SGK1
serum/glucocorticoid regulated kinase 1
chr6_+_41889191 0.593 BYSL
bystin-like
chr10_-_3827418 0.585 NM_001160124
NM_001160125
NM_001300
KLF6


Kruppel-like factor 6


chr9_-_140353748 0.584 NELF
nasal embryonic LHRH factor
chr20_+_44420606 0.582 DNTTIP1
deoxynucleotidyltransferase, terminal, interacting protein 1
chr19_-_44100127 0.581 NM_001007561
IRGQ
immunity-related GTPase family, Q
chr20_-_48530275 0.580 NM_001135773
SPATA2
spermatogenesis associated 2
chr7_-_44924946 0.579 NM_033224
PURB
purine-rich element binding protein B
chr2_-_43453724 0.571 ZFP36L2
zinc finger protein 36, C3H type-like 2
chr7_+_143078358 0.569 NM_001010972
NM_003461
ZYX

zyxin

chr6_-_88411872 0.568 AKIRIN2
akirin 2
chr19_-_10514185 0.564 CDC37
cell division cycle 37 homolog (S. cerevisiae)
chrX_+_72667089 0.558 NM_005193
CDX4
caudal type homeobox 4
chr6_-_88411948 0.556 AKIRIN2
akirin 2
chr17_-_71308118 0.556 NM_012121
CDC42EP4
CDC42 effector protein (Rho GTPase binding) 4
chr4_-_76598558 0.550 G3BP2
GTPase activating protein (SH3 domain) binding protein 2
chr7_-_45151272 0.545 TBRG4
transforming growth factor beta regulator 4
chr12_-_123380628 0.539 VPS37B
vacuolar protein sorting 37 homolog B (S. cerevisiae)
chr22_-_44258210 0.537 NM_014351
SULT4A1
sulfotransferase family 4A, member 1
chr2_+_220309373 0.536 SPEG
SPEG complex locus
chr2_+_61108702 0.530 REL
v-rel reticuloendotheliosis viral oncogene homolog (avian)
chr12_+_132628978 0.527 NM_024078
NOC4L
nucleolar complex associated 4 homolog (S. cerevisiae)
chr11_+_128563955 0.526 FLI1
Friend leukemia virus integration 1
chr6_+_135818938 0.526 LINC00271
long intergenic non-protein coding RNA 271
chr6_+_47445440 0.526 NM_012120
CD2AP
CD2-associated protein
chr17_-_8151373 0.526 NM_025099
CTC1
CTS telomere maintenance complex component 1

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.15 1.28e-09 GO:0009987 cellular process
1.31 2.01e-06 GO:0044260 cellular macromolecule metabolic process
1.26 6.95e-05 GO:0043170 macromolecule metabolic process
1.20 4.23e-04 GO:0044237 cellular metabolic process
1.30 8.71e-04 GO:0007165 signal transduction
1.44 9.61e-04 GO:0010467 gene expression
1.28 1.06e-03 GO:0023052 signaling
1.18 3.93e-03 GO:0044238 primary metabolic process
13.59 5.66e-03 GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis
1.25 1.02e-02 GO:0032502 developmental process
1.40 1.51e-02 GO:0016070 RNA metabolic process
1.58 1.94e-02 GO:0006351 transcription, DNA-dependent
1.23 3.15e-02 GO:0051716 cellular response to stimulus
1.36 3.24e-02 GO:0043412 macromolecule modification
1.37 3.89e-02 GO:0006464 protein modification process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.14 8.42e-04 GO:0005737 cytoplasm
1.09 1.54e-03 GO:0044424 intracellular part
1.09 3.27e-03 GO:0005622 intracellular
1.17 8.81e-03 GO:0005634 nucleus
1.10 2.17e-02 GO:0043226 organelle
1.10 2.66e-02 GO:0043229 intracellular organelle

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.24 8.52e-10 GO:0005515 protein binding
1.68 1.18e-05 GO:0001071 nucleic acid binding transcription factor activity
1.68 1.18e-05 GO:0003700 sequence-specific DNA binding transcription factor activity
1.10 1.74e-05 GO:0005488 binding
1.67 2.84e-03 GO:0043565 sequence-specific DNA binding
1.99 4.82e-03 GO:0016563 transcription activator activity
1.90 4.10e-02 GO:0008134 transcription factor binding