Motif ID: KLF12.p2

Z-value: 2.178


Transcription factors associated with KLF12.p2:

Gene SymbolEntrez IDGene Name
KLF12 11278 Kruppel-like factor 12

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.p-valuePlot
KLF12chr13_-_747079130.271.9e-01Click!


Activity profile for motif KLF12.p2.

activity profile for motif KLF12.p2


Sorted Z-values histogram for motif KLF12.p2

Sorted Z-values for motif KLF12.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of KLF12.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr5_+_137801166 9.119 EGR1
early growth response 1
chr5_+_137801178 7.005 NM_001964
 EGR1
early growth response 1
chr19_-_14260728 5.356 LPHN1
latrophilin 1
chr1_+_61869699 4.960 NFIA
nuclear factor I/A
chr2_-_225266710 3.803 NM_001122779
NM_024785
 FAM124B

family with sequence similarity 124B

chr13_+_58207858 3.784 PCDH17
protocadherin 17
chr2_-_220436010 3.668 OBSL1
obscurin-like 1
chr3_+_193853930 3.277 NM_005524
 HES1
hairy and enhancer of split 1, (Drosophila)
chr2_-_220436267 2.991 NM_001173408
NM_001173431
NM_015311
 OBSL1


obscurin-like 1


chr20_+_34742656 2.870 NM_012156
 EPB41L1
erythrocyte membrane protein band 4.1-like 1
chr6_-_13486986 2.849 GFOD1
glucose-fructose oxidoreductase domain containing 1
chr17_+_38119225 2.848 NM_178171
 GSDMA
gasdermin A
chr17_-_47841517 2.647 NM_030802
 FAM117A
family with sequence similarity 117, member A
chr17_-_47841468 2.614 FAM117A
family with sequence similarity 117, member A
chr12_+_79258517 2.474 SYT1
synaptotagmin I
chr3_+_193853937 2.450 HES1
hairy and enhancer of split 1, (Drosophila)
chr2_+_203499819 2.408 NM_173511
 FAM117B
family with sequence similarity 117, member B
chr12_+_79258588 2.373 SYT1
synaptotagmin I
chr19_+_2476122 2.337 NM_015675
 GADD45B
growth arrest and DNA-damage-inducible, beta
chr8_-_22550057 2.231 NM_001199881
 EGR3
early growth response 3

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 16 of 16 entries
enrichment   p-value GO term description
1.38 2.67e-02 GO:0051253 negative regulation of RNA metabolic process
1.37 1.18e-02 GO:0051172 negative regulation of nitrogen compound metabolic process
1.36 1.98e-02 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.27 2.54e-02 GO:0010646 regulation of cell communication
1.22 3.47e-02 GO:0009966 regulation of signal transduction
1.21 3.50e-02 GO:0023051 regulation of signaling
1.19 7.20e-03 GO:0048523 negative regulation of cellular process
1.17 3.54e-02 GO:0048519 negative regulation of biological process
1.17 4.44e-02 GO:0065008 regulation of biological quality
1.15 9.38e-04 GO:0023052 signaling
1.15 4.92e-03 GO:0007165 signal transduction
1.13 4.27e-02 GO:0007275 multicellular organismal development
1.09 3.76e-03 GO:0050794 regulation of cellular process
1.08 3.91e-03 GO:0065007 biological regulation
1.08 1.61e-02 GO:0050789 regulation of biological process
1.07 4.83e-07 GO:0009987 cellular process

Gene overrepresentation in compartment category:

Showing 1 to 4 of 4 entries
enrichment   p-value GO term description
1.06 6.12e-03 GO:0043229 intracellular organelle
1.06 7.97e-03 GO:0043226 organelle
1.05 6.03e-03 GO:0044424 intracellular part
1.04 1.53e-02 GO:0005622 intracellular

Gene overrepresentation in function category:

Showing 1 to 2 of 2 entries
enrichment   p-value GO term description
1.09 2.76e-04 GO:0005515 protein binding
1.05 1.31e-03 GO:0005488 binding