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Motif ID: KLF12.p2

Z-value: 2.178

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr5_+_137801166	9.119		EGR1	early growth response 1
chr5_+_137801178	7.005	NM_001964	EGR1	early growth response 1
chr19_-_14260728	5.356		LPHN1	latrophilin 1
chr1_+_61869699	4.960		NFIA	nuclear factor I/A
chr2_-_225266710	3.803	NM_001122779 NM_024785	FAM124B	family with sequence similarity 124B
chr13_+_58207858	3.784		PCDH17	protocadherin 17
chr2_-_220436010	3.668		OBSL1	obscurin-like 1
chr3_+_193853930	3.277	NM_005524	HES1	hairy and enhancer of split 1, (Drosophila)
chr2_-_220436267	2.991	NM_001173408 NM_001173431 NM_015311	OBSL1	obscurin-like 1
chr20_+_34742656	2.870	NM_012156	EPB41L1	erythrocyte membrane protein band 4.1-like 1
chr6_-_13486986	2.849		GFOD1	glucose-fructose oxidoreductase domain containing 1
chr17_+_38119225	2.848	NM_178171	GSDMA	gasdermin A
chr17_-_47841517	2.647	NM_030802	FAM117A	family with sequence similarity 117, member A
chr17_-_47841468	2.614		FAM117A	family with sequence similarity 117, member A
chr12_+_79258517	2.474		SYT1	synaptotagmin I
chr3_+_193853937	2.450		HES1	hairy and enhancer of split 1, (Drosophila)
chr2_+_203499819	2.408	NM_173511	FAM117B	family with sequence similarity 117, member B
chr12_+_79258588	2.373		SYT1	synaptotagmin I
chr19_+_2476122	2.337	NM_015675	GADD45B	growth arrest and DNA-damage-inducible, beta
chr8_-_22550057	2.231	NM_001199881	EGR3	early growth response 3
chr4_-_16900348	2.166	NM_001130834 NM_001290	LDB2	LIM domain binding 2
chr7_-_27213873	2.137	NM_018951	HOXA10	homeobox A10
chr1_+_25944610	2.128		MAN1C1	mannosidase, alpha, class 1C, member 1
chr4_+_30721865	2.112	NM_032456 NM_001173523 NM_002589 NM_032457	PCDH7	protocadherin 7
chr19_+_39155209	2.107
chr1_+_25943958	2.089	NM_020379	MAN1C1	mannosidase, alpha, class 1C, member 1
chr18_+_20715726	2.080	NM_001100619	CABLES1	Cdk5 and Abl enzyme substrate 1
chr10_-_81205091	2.062	NM_153367	ZCCHC24	zinc finger, CCHC domain containing 24
chr4_-_16900256	2.048		LDB2	LIM domain binding 2
chr19_+_13263890	2.001		IER2	immediate early response 2
chrX_-_63005212	1.986	NM_001173479	ARHGEF9	Cdc42 guanine nucleotide exchange factor (GEF) 9
chr17_-_61920256	1.982		SMARCD2	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2
chr1_+_203274646	1.960	NM_006763	BTG2	BTG family, member 2
chr11_+_119020572	1.925		ABCG4	ATP-binding cassette, sub-family G (WHITE), member 4
chr20_+_42574535	1.921	NM_001098798	TOX2	TOX high mobility group box family member 2
chr18_+_77659446	1.915
chr6_+_160182988	1.907	NM_005891	ACAT2	acetyl-CoA acetyltransferase 2
chr6_+_160183062	1.907		ACAT2	acetyl-CoA acetyltransferase 2
chr6_+_116832807	1.876	NM_153711	FAM26E	family with sequence similarity 26, member E
chr17_+_38599651	1.858	NM_001552	IGFBP4	insulin-like growth factor binding protein 4
chr20_-_39317875	1.857	NM_005461	MAFB	v-maf musculoaponeurotic fibrosarcoma oncogene homolog B (avian)
chr9_-_134151905	1.838	NM_033387	FAM78A	family with sequence similarity 78, member A
chr5_-_172198160	1.834	NM_004417	DUSP1	dual specificity phosphatase 1
chr19_-_6442004	1.745		SLC25A23	solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
chr2_+_112656200	1.706		MERTK	c-mer proto-oncogene tyrosine kinase
chr7_+_94023872	1.702	NM_000089	COL1A2	collagen, type I, alpha 2
chrX_-_74743085	1.695		ZDHHC15	zinc finger, DHHC-type containing 15
chr19_+_50194348	1.689	NM_001136052 NM_001199752 NM_001199753 NM_152359	CPT1C	carnitine palmitoyltransferase 1C
chr12_+_79258448	1.679	NM_005639	SYT1	synaptotagmin I
chr17_-_61920328	1.670	NM_001098426	SMARCD2	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2
chr2_+_176994421	1.663	NM_001199747 NM_001199746 NM_019558	HOXD8	homeobox D8
chr11_-_2018568	1.659		H19	H19, imprinted maternally expressed transcript (non-protein coding)
chr16_-_4562979	1.655		C16orf5	chromosome 16 open reading frame 5
chr4_-_16900028	1.632		LDB2	LIM domain binding 2
chr7_+_1097140	1.629	NM_138445	GPR146	G protein-coupled receptor 146
chr3_+_8543539	1.617		LMCD1	LIM and cysteine-rich domains 1
chr11_+_7535213	1.599		PPFIBP2	PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr2_-_73520448	1.587	NM_001965	EGR4	early growth response 4
chr14_+_58765209	1.553	NM_002892 NM_023000 NM_023001	ARID4A	AT rich interactive domain 4A (RBP1-like)
chrX_-_70473979	1.550	NM_201599	ZMYM3	zinc finger, MYM-type 3
chr21_-_47604360	1.545	NM_001142854 NM_032261	C21orf56	chromosome 21 open reading frame 56
chr4_-_74904329	1.542	NM_002090	CXCL3	chemokine (C-X-C motif) ligand 3
chrX_-_70473941	1.530		ZMYM3	zinc finger, MYM-type 3
chr8_-_93029864	1.494	NM_175636	RUNX1T1	runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr3_-_49058426	1.479	NM_018114	DALRD3	DALR anticodon binding domain containing 3
chr4_+_30722191	1.475		PCDH7	protocadherin 7
chr8_+_37654395	1.466	NM_032777	GPR124	G protein-coupled receptor 124
chr8_+_37654406	1.454		GPR124	G protein-coupled receptor 124
chrX_-_74743299	1.453	NM_001146256 NM_001146257 NM_144969	ZDHHC15	zinc finger, DHHC-type containing 15
chr21_-_47604340	1.434		C21orf56	chromosome 21 open reading frame 56
chr8_+_37654833	1.431		GPR124	G protein-coupled receptor 124
chr10_+_75545296	1.418		KIAA0913	KIAA0913
chr11_-_119211034	1.400		MFRP	membrane frizzled-related protein
chr2_-_220083699	1.399	NM_005689	ABCB6	ATP-binding cassette, sub-family B (MDR/TAP), member 6
chr17_+_1665342	1.386		SERPINF1	serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr10_-_64576074	1.377		EGR2	early growth response 2
chr20_-_2821245	1.360	NM_022760	FAM113A	family with sequence similarity 113, member A
chr2_-_220083658	1.355		ABCB6	ATP-binding cassette, sub-family B (MDR/TAP), member 6
chr5_-_81046858	1.353		SSBP2	single-stranded DNA binding protein 2
chr17_+_1665281	1.349		SERPINF1	serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr1_+_2005083	1.319	NM_001033581	PRKCZ	protein kinase C, zeta
chr3_+_39851028	1.312	NM_015460	MYRIP	myosin VIIA and Rab interacting protein
chr5_-_81046943	1.311	NM_012446	SSBP2	single-stranded DNA binding protein 2
chr17_+_61699786	1.301	NM_002401 NM_203351	MAP3K3	mitogen-activated protein kinase kinase kinase 3
chr11_+_121461070	1.297		SORL1	sortilin-related receptor, L(DLR class) A repeats containing
chr4_-_149363498	1.293	NM_000901 NM_001166104	NR3C2	nuclear receptor subfamily 3, group C, member 2
chr15_+_41221530	1.287	NM_019074	DLL4	delta-like 4 (Drosophila)
chr9_+_34652125	1.272	NM_001142784	IL11RA	interleukin 11 receptor, alpha
chr19_+_44116252	1.264	NM_001145641	SRRM5	serine/arginine repetitive matrix 5
chr17_-_56358118	1.257		MPO	myeloperoxidase
chr10_-_102279590	1.240	NM_015490	SEC31B	SEC31 homolog B (S. cerevisiae)
chr9_+_130860769	1.229		SLC25A25	solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25
chr9_+_115513050	1.219	NM_001012994	SNX30	sorting nexin family member 30
chr11_-_2018446	1.219		H19	H19, imprinted maternally expressed transcript (non-protein coding)
chr1_+_92495484	1.212	NM_173567	EPHX4	epoxide hydrolase 4
chr15_-_69113213	1.206		ANP32A	acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
chr22_-_37915209	1.194	NM_014550	CARD10	caspase recruitment domain family, member 10
chr20_-_2821120	1.191		FAM113A	family with sequence similarity 113, member A
chr9_+_130860816	1.188	NM_052901 NM_001006643	SLC25A25	solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25
chr19_+_42829760	1.186	NM_001410	MEGF8	multiple EGF-like-domains 8
chr1_+_162351519	1.171	NM_001085375	C1orf226	chromosome 1 open reading frame 226
chr21_-_47604300	1.166		C21orf56	chromosome 21 open reading frame 56
chr17_+_48172508	1.145	NM_001199900 NM_002611 NM_001199899	PDK2	pyruvate dehydrogenase kinase, isozyme 2
chr1_-_234743488	1.124		IRF2BP2	interferon regulatory factor 2 binding protein 2
chr15_-_69113089	1.122		ANP32A	acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
chr1_+_164528586	1.111	NM_001204961 NM_001204963 NM_002585	PBX1	pre-B-cell leukemia homeobox 1
chr4_-_74964996	1.109	NM_002089	CXCL2	chemokine (C-X-C motif) ligand 2
chr19_-_17356022	1.092	NM_005234	NR2F6	nuclear receptor subfamily 2, group F, member 6
chr14_+_57735605	1.077	NM_018229	MUDENG	MU-2/AP1M2 domain containing, death-inducing
chr11_+_66624875	1.069	NM_024036	LRFN4	leucine rich repeat and fibronectin type III domain containing 4
chr13_-_111567415	1.067	NM_017664	ANKRD10	ankyrin repeat domain 10
chr16_+_3019341	1.065	NM_152341	PAQR4	progestin and adipoQ receptor family member IV
chr17_+_47866061	1.059		KAT7	K(lysine) acetyltransferase 7
chr12_+_122064448	1.044	NM_032790	ORAI1	ORAI calcium release-activated calcium modulator 1
chrX_-_74742871	1.037		ZDHHC15	zinc finger, DHHC-type containing 15
chr3_+_57094468	1.035	NM_181727	SPATA12	spermatogenesis associated 12
chr17_+_61562177	1.031	NM_001178057 NM_152830	ACE	angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
chr1_+_61542928	1.029	NM_001145511	NFIA	nuclear factor I/A
chr12_+_13349720	1.028		EMP1	epithelial membrane protein 1
chr17_+_61699715	1.027		MAP3K3	mitogen-activated protein kinase kinase kinase 3
chr19_+_39899749	1.026
chr13_-_72440557	1.023		DACH1	dachshund homolog 1 (Drosophila)
chr17_+_1665233	1.019	NM_002615	SERPINF1	serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr4_-_74964836	1.013		CXCL2	chemokine (C-X-C motif) ligand 2
chr3_-_148804122	1.005	NM_003071 NM_139048	HLTF	helicase-like transcription factor
chr5_+_68710938	1.004	NM_001038603 NM_001244734	MARVELD2	MARVEL domain containing 2
chr7_-_27224762	1.002	NM_005523	HOXA11	homeobox A11
chr11_-_2017822	1.001		H19	H19, imprinted maternally expressed transcript (non-protein coding)
chr14_-_23821423	0.986	NM_020372	SLC22A17	solute carrier family 22, member 17
chr11_-_119211526	0.977		C1QTNF5 MFRP	C1q and tumor necrosis factor related protein 5 membrane frizzled-related protein
chr3_-_128207366	0.977	NM_001145661	GATA2	GATA binding protein 2
chr13_-_72440143	0.961		DACH1	dachshund homolog 1 (Drosophila)
chr11_+_7535000	0.961	NM_003621	PPFIBP2	PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr8_+_143808593	0.961	NM_016647	C8orf55	chromosome 8 open reading frame 55
chr16_+_30389632	0.960	NM_001214906 NM_001214907	ZNF48	zinc finger protein 48
chr20_+_42543417	0.960	NM_001098797	TOX2	TOX high mobility group box family member 2
chr7_+_2598646	0.951		IQCE	IQ motif containing E
chr1_-_94586678	0.945	NM_000350	ABCA4	ATP-binding cassette, sub-family A (ABC1), member 4
chr2_-_193059249	0.944		TMEFF2	transmembrane protein with EGF-like and two follistatin-like domains 2
chr17_-_8534008	0.942	NM_005964	MYH10	myosin, heavy chain 10, non-muscle
chr3_-_128212027	0.941	NM_032638	GATA2	GATA binding protein 2
chr1_+_901876	0.941	NM_001160184 NM_032129	PLEKHN1	pleckstrin homology domain containing, family N member 1
chr3_+_25470067	0.940		RARB	retinoic acid receptor, beta
chr20_-_2821789	0.940		FAM113A	family with sequence similarity 113, member A
chr19_+_2222415	0.939		DOT1L	DOT1-like, histone H3 methyltransferase (S. cerevisiae)
chr4_+_6271588	0.934		WFS1	Wolfram syndrome 1 (wolframin)
chr6_-_42946887	0.931		PEX6	peroxisomal biogenesis factor 6
chrX_-_54522318	0.931	NM_004463	FGD1	FYVE, RhoGEF and PH domain containing 1
chr14_-_91526912	0.926	NM_004755 NM_182398	RPS6KA5	ribosomal protein S6 kinase, 90kDa, polypeptide 5
chr11_-_33891361	0.924	NM_001142316	LMO2	LIM domain only 2 (rhombotin-like 1)
chr4_+_6271558	0.921	NM_001145853 NM_006005	WFS1	Wolfram syndrome 1 (wolframin)
chr6_-_111136330	0.917		CDK19	cyclin-dependent kinase 19
chr10_+_102123420	0.917
chr1_+_154474694	0.916	NM_001098475 NM_182499	TDRD10	tudor domain containing 10
chr11_-_2018334	0.911		H19	H19, imprinted maternally expressed transcript (non-protein coding)
chr10_-_72083678	0.909		LRRC20	leucine rich repeat containing 20
chr12_-_10826890	0.909	NM_018423	STYK1	serine/threonine/tyrosine kinase 1
chr15_-_52587851	0.908	NM_018728	MYO5C	myosin VC
chr12_-_46766019	0.904		SLC38A2	solute carrier family 38, member 2
chr17_-_73840495	0.902		UNC13D	unc-13 homolog D (C. elegans)
chr16_+_83932729	0.902	NM_012213	MLYCD	malonyl-CoA decarboxylase
chrX_+_138612894	0.902	NM_000133	F9	coagulation factor IX
chr17_-_39471944	0.901	NM_031964	KRTAP17-1	keratin associated protein 17-1
chr8_-_17580024	0.901	NM_001166393	MTUS1	microtubule associated tumor suppressor 1
chr12_+_12938540	0.898	NM_030817	APOLD1	apolipoprotein L domain containing 1
chr2_-_220408264	0.898	NM_024536	CHPF	chondroitin polymerizing factor
chr16_+_31225341	0.898	NM_001008274	TRIM72	tripartite motif containing 72
chr1_+_76540374	0.897	NM_001160011 NM_152996	ST6GALNAC3	ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3
chr6_-_111136407	0.897	NM_015076	CDK19	cyclin-dependent kinase 19
chr4_+_6271605	0.895		WFS1	Wolfram syndrome 1 (wolframin)
chr3_+_194407412	0.893		FAM43A	family with sequence similarity 43, member A
chr15_-_89456592	0.891	NM_001114614 NM_005928	MFGE8	milk fat globule-EGF factor 8 protein
chr19_-_11308457	0.888		KANK2	KN motif and ankyrin repeat domains 2
chr2_-_222436996	0.884	NM_004438	EPHA4	EPH receptor A4
chr17_-_39150384	0.883	NM_033185	KRTAP3-3	keratin associated protein 3-3
chr12_-_76425207	0.882		PHLDA1	pleckstrin homology-like domain, family A, member 1
chr11_+_47290893	0.882	NM_130470	MADD	MAP-kinase activating death domain
chr2_-_220083394	0.881		ABCB6	ATP-binding cassette, sub-family B (MDR/TAP), member 6
chr1_-_33841142	0.880	NM_198040	PHC2	polyhomeotic homolog 2 (Drosophila)
chr9_+_133971902	0.876		AIF1L	allograft inflammatory factor 1-like
chr16_+_29817426	0.873		MAZ	MYC-associated zinc finger protein (purine-binding transcription factor)
chr17_+_4843883	0.870		RNF167	ring finger protein 167
chr9_+_139972195	0.868		UAP1L1	UDP-N-acteylglucosamine pyrophosphorylase 1-like 1
chr1_+_155279514	0.867		FDPS	farnesyl diphosphate synthase
chr9_-_100459623	0.860	NM_000380	XPA	xeroderma pigmentosum, complementation group A
chrX_+_151999510	0.857	NM_001129765 NM_015922	NSDHL	NAD(P) dependent steroid dehydrogenase-like
chr20_-_35885276	0.855	NM_001184731 NM_021081	GHRH	growth hormone releasing hormone
chr22_+_31489343	0.853		SMTN	smoothelin
chr1_-_22263676	0.852	NM_005529	HSPG2	heparan sulfate proteoglycan 2
chr7_-_27702504	0.850	NM_152740	HIBADH	3-hydroxyisobutyrate dehydrogenase
chr17_+_27071008	0.840	NM_004295	TRAF4	TNF receptor-associated factor 4
chr1_+_212458867	0.834	NM_006243	PPP2R5A	protein phosphatase 2, regulatory subunit B', alpha
chr10_+_82173574	0.834	NM_001243778 NM_001243782	C10orf58	chromosome 10 open reading frame 58
chr7_+_106685007	0.830	NM_002736	PRKAR2B	protein kinase, cAMP-dependent, regulatory, type II, beta
chr2_+_220042986	0.829		FAM134A	family with sequence similarity 134, member A
chr10_-_105452878	0.829		SH3PXD2A	SH3 and PX domains 2A
chr7_+_107110501	0.828	NM_005295	GPR22	G protein-coupled receptor 22
chr8_-_22549901	0.827	NM_001199880	EGR3	early growth response 3
chr6_-_33266297	0.826		RGL2	ral guanine nucleotide dissociation stimulator-like 2
chr19_+_50353942	0.822		PTOV1	prostate tumor overexpressed 1

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.07	4.83e-07	GO:0009987	cellular process
1.15	9.38e-04	GO:0023052	signaling
1.09	3.76e-03	GO:0050794	regulation of cellular process
1.08	3.91e-03	GO:0065007	biological regulation
1.15	4.92e-03	GO:0007165	signal transduction
1.19	7.20e-03	GO:0048523	negative regulation of cellular process
1.37	1.18e-02	GO:0051172	negative regulation of nitrogen compound metabolic process
1.08	1.61e-02	GO:0050789	regulation of biological process
1.36	1.98e-02	GO:0045934	negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.27	2.54e-02	GO:0010646	regulation of cell communication
1.38	2.67e-02	GO:0051253	negative regulation of RNA metabolic process
1.22	3.47e-02	GO:0009966	regulation of signal transduction
1.21	3.50e-02	GO:0023051	regulation of signaling
1.17	3.54e-02	GO:0048519	negative regulation of biological process
1.13	4.27e-02	GO:0007275	multicellular organismal development
1.17	4.44e-02	GO:0065008	regulation of biological quality

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.05	6.03e-03	GO:0044424	intracellular part
1.06	6.12e-03	GO:0043229	intracellular organelle
1.06	7.97e-03	GO:0043226	organelle
1.04	1.53e-02	GO:0005622	intracellular

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.09	2.76e-04	GO:0005515	protein binding
1.05	1.31e-03	GO:0005488	binding