Motif ID: LHX3,4.p2

Z-value: 1.308


Transcription factors associated with LHX3,4.p2:

Gene SymbolEntrez IDGene Name
LHX3 8022 LIM homeobox 3
LHX4 89884 LIM homeobox 4

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.p-valuePlot
LHX3chr9_-_1390948860.582.2e-03Click!
LHX4chr1_+_180199432-0.359.0e-02Click!


Activity profile for motif LHX3,4.p2.

activity profile for motif LHX3,4.p2


Sorted Z-values histogram for motif LHX3,4.p2

Sorted Z-values for motif LHX3,4.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of LHX3,4.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr8_+_17396285 13.687 NM_001164771
NM_003046
 SLC7A2

solute carrier family 7 (cationic amino acid transporter, y+ system), member 2

chr6_-_29527701 10.573 NM_006398
 UBD
ubiquitin D
chr7_-_92777657 10.459 NM_152703
 SAMD9L
sterile alpha motif domain containing 9-like
chr4_-_76957139 8.727 NM_005409
 CXCL11
chemokine (C-X-C motif) ligand 11
chr10_+_91152321 7.343 NM_001548
 IFIT1
interferon-induced protein with tetratricopeptide repeats 1
chr4_-_76944585 5.263 NM_001565
 CXCL10
chemokine (C-X-C motif) ligand 10
chr1_-_150738292 4.452 NM_001199739
NM_004079
 CTSS

cathepsin S

chr9_+_118916069 4.319 NM_002581
 PAPPA
pregnancy-associated plasma protein A, pappalysin 1
chr1_-_150738232 4.301 CTSS
cathepsin S
chr21_+_43619798 4.175 NM_207627
NM_207628
 ABCG1

ATP-binding cassette, sub-family G (WHITE), member 1

chr7_-_139763520 4.044 NM_022750
 PARP12
poly (ADP-ribose) polymerase family, member 12
chr3_-_79817058 3.923 NM_002941
 ROBO1
roundabout, axon guidance receptor, homolog 1 (Drosophila)
chr6_+_26440699 3.675 NM_001242803
NM_006994
NM_197974
 BTN3A3


butyrophilin, subfamily 3, member A3


chr1_-_150738255 3.630 CTSS
cathepsin S
chr12_-_16760935 3.461 NM_001001395
NM_001243609
 LMO3

LIM domain only 3 (rhombotin-like 2)

chr3_-_157221362 3.284 NM_001167915
NM_001167916
 VEPH1

ventricular zone expressed PH domain homolog 1 (zebrafish)

chr5_-_150467220 3.205 NM_001252390
 TNIP1
TNFAIP3 interacting protein 1
chr15_+_67418053 3.181 NM_001145102
 SMAD3
SMAD family member 3
chr4_-_122148620 3.126 NM_001244764
 TNIP3
TNFAIP3 interacting protein 3
chr2_+_162272892 3.110 TBR1
T-box, brain, 1

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 2 of 2 entries
enrichment   p-value GO term description
1.27 4.17e-03 GO:0032501 multicellular organismal process
1.22 1.11e-02 GO:0050896 response to stimulus

Gene overrepresentation in compartment category:

Showing 1 to 7 of 7 entries
enrichment   p-value GO term description
2.73 4.67e-02 GO:0034703 cation channel complex
2.13 2.46e-02 GO:0005578 proteinaceous extracellular matrix
1.54 1.75e-02 GO:0005887 integral to plasma membrane
1.53 1.96e-05 GO:0044459 plasma membrane part
1.51 3.30e-02 GO:0031226 intrinsic to plasma membrane
1.36 1.23e-05 GO:0005886 plasma membrane
1.35 1.81e-05 GO:0071944 cell periphery

Gene overrepresentation in function category:

Showing 1 to 8 of 8 entries
enrichment   p-value GO term description
21.71 4.69e-02 GO:0034056 estrogen response element binding
2.75 4.47e-02 GO:0022843 voltage-gated cation channel activity
2.08 1.06e-02 GO:0022838 substrate-specific channel activity
2.05 1.76e-02 GO:0005216 ion channel activity
2.01 2.06e-02 GO:0015267 channel activity
2.01 2.17e-02 GO:0022803 passive transmembrane transporter activity
1.69 4.57e-02 GO:0015075 ion transmembrane transporter activity
1.61 3.96e-02 GO:0022857 transmembrane transporter activity