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• Activity deltas table
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Motif ID: MZF1.p2

Z-value: 1.147

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr1_+_211432726	4.128		RCOR3	REST corepressor 3
chr1_+_211432732	2.884		RCOR3	REST corepressor 3
chr2_+_48757292	2.594	NM_001198595 NM_006873	STON1	stonin 1
chr11_-_68518910	1.926		MTL5	metallothionein-like 5, testis-specific (tesmin)
chr1_+_164528586	1.782	NM_001204961 NM_001204963 NM_002585	PBX1	pre-B-cell leukemia homeobox 1
chr18_-_22932109	1.695	NM_015461	ZNF521	zinc finger protein 521
chr1_+_61547625	1.550	NM_001134673 NM_005595	NFIA	nuclear factor I/A
chr5_+_139028483	1.536		CXXC5	CXXC finger protein 5
chr18_-_22931970	1.491		ZNF521	zinc finger protein 521
chr5_-_88179278	1.471	NM_001193350 NM_002397	MEF2C	myocyte enhancer factor 2C
chr11_-_73309090	1.462	NM_015159	FAM168A	family with sequence similarity 168, member A
chrX_-_119694871	1.377		CUL4B	cullin 4B
chrX_-_119694719	1.375	NM_001079872	CUL4B	cullin 4B
chr5_-_73936299	1.313		ENC1	ectodermal-neural cortex 1 (with BTB-like domain)
chr2_+_182756665	1.307		SSFA2	sperm specific antigen 2
chrX_-_119694492	1.275		CUL4B	cullin 4B
chr18_-_22930826	1.188
chr2_-_217236666	1.185	NM_020814	MARCH4	membrane-associated ring finger (C3HC4) 4
chr5_-_88178964	1.174		MEF2C	myocyte enhancer factor 2C
chr2_-_165477986	1.158		GRB14	growth factor receptor-bound protein 14
chr9_+_131451823	1.150		SET	SET nuclear oncogene
chr4_-_16900028	1.148		LDB2	LIM domain binding 2
chr1_+_211432855	1.146		RCOR3	REST corepressor 3
chr4_-_16900256	1.142		LDB2	LIM domain binding 2
chr13_-_72441312	1.142	NM_004392 NM_080759 NM_080760	DACH1	dachshund homolog 1 (Drosophila)
chr11_+_5617330	1.133	NM_058166	TRIM6	tripartite motif containing 6
chr12_-_118406027	1.124	NM_173598	KSR2	kinase suppressor of ras 2
chr3_-_18466759	1.105	NM_001195470 NM_002971	SATB1	SATB homeobox 1
chr14_-_54423448	1.096	NM_001202 NM_130850	BMP4	bone morphogenetic protein 4
chr18_-_29264394	1.093	NM_004775	B4GALT6	UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6
chr6_+_17393610	1.087	NM_006366	CAP2	CAP, adenylate cyclase-associated protein, 2 (yeast)
chr5_-_81046858	1.046		SSBP2	single-stranded DNA binding protein 2
chr13_+_58205943	1.033		PCDH17	protocadherin 17
chr9_-_14314036	1.023	NM_001190737 NM_005596	NFIB	nuclear factor I/B
chr7_+_104654494	1.020	NM_018682 NM_182931	MLL5	myeloid/lymphoid or mixed-lineage leukemia 5 (trithorax homolog, Drosophila)
chr9_-_14313899	1.012		NFIB	nuclear factor I/B
chr2_-_61697846	1.002	NM_014709	USP34	ubiquitin specific peptidase 34
chr4_-_174450529	0.969		HAND2	heart and neural crest derivatives expressed 2
chr18_+_77155927	0.968		NFATC1	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
chr13_+_58205788	0.967	NM_001040429	PCDH17	protocadherin 17
chr12_-_56615484	0.948	NM_001242826	RNF41	ring finger protein 41
chr5_+_56111379	0.948		MAP3K1	mitogen-activated protein kinase kinase kinase 1
chr8_+_144816287	0.939		LOC100128338	uncharacterized LOC100128338
chr9_-_124990949	0.928	NM_014368 NM_199160	LHX6	LIM homeobox 6
chr17_-_47841517	0.923	NM_030802	FAM117A	family with sequence similarity 117, member A
chr2_-_61697899	0.921		USP34	ubiquitin specific peptidase 34
chr18_+_77155966	0.915		NFATC1	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
chr9_+_130374466	0.899	NM_001032221 NM_003165	STXBP1	syntaxin binding protein 1
chrX_+_66763868	0.892	NM_000044	AR	androgen receptor
chr3_+_37903643	0.888	NM_001008392 NM_005808	CTDSPL	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like
chr4_-_16900348	0.888	NM_001130834 NM_001290	LDB2	LIM domain binding 2
chr4_-_102268333	0.884		PPP3CA	protein phosphatase 3, catalytic subunit, alpha isozyme
chr19_-_36391448	0.883	NM_139239	NFKBID	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, delta
chr4_+_30721865	0.869	NM_032456 NM_001173523 NM_002589 NM_032457	PCDH7	protocadherin 7
chr19_-_291335	0.868	NM_003712 NM_177526	PPAP2C	phosphatidic acid phosphatase type 2C
chr19_-_291168	0.866	NM_177543	PPAP2C	phosphatidic acid phosphatase type 2C
chr12_-_56615679	0.866	NM_005785 NM_194358 NM_194359	RNF41	ring finger protein 41
chr8_-_127570465	0.865		FAM84B	family with sequence similarity 84, member B
chr14_+_24867926	0.860	NM_025081	NYNRIN	NYN domain and retroviral integrase containing
chr7_-_23509631	0.856
chr12_+_51158242	0.853		ATF1	activating transcription factor 1
chr11_-_130184459	0.848	NM_014155	ZBTB44	zinc finger and BTB domain containing 44
chr14_-_91526912	0.836	NM_004755 NM_182398	RPS6KA5	ribosomal protein S6 kinase, 90kDa, polypeptide 5
chr5_-_81046943	0.834	NM_012446	SSBP2	single-stranded DNA binding protein 2
chr8_-_9008138	0.826	NM_024607	PPP1R3B	protein phosphatase 1, regulatory subunit 3B
chr3_+_20081853	0.823		KAT2B	K(lysine) acetyltransferase 2B
chr10_-_69834950	0.808		HERC4	hect domain and RLD 4
chr2_+_148778573	0.802	NM_018328	MBD5	methyl-CpG binding domain protein 5
chr9_-_14313943	0.797		NFIB	nuclear factor I/B
chr5_+_176560627	0.795	NM_022455	NSD1	nuclear receptor binding SET domain protein 1
chr7_-_149470294	0.792	NM_207336	ZNF467	zinc finger protein 467
chr5_+_139028025	0.791	NM_016463	CXXC5	CXXC finger protein 5
chr21_+_27107731	0.760		GABPA	GA binding protein transcription factor, alpha subunit 60kDa
chr4_-_85887543	0.754	NM_014991	WDFY3	WD repeat and FYVE domain containing 3
chr22_-_28197469	0.752	NM_002430	MN1	meningioma (disrupted in balanced translocation) 1
chr3_+_32280211	0.747		CMTM8	CKLF-like MARVEL transmembrane domain containing 8
chr2_+_8822112	0.735	NM_002166	ID2	inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
chr9_+_131451847	0.732		SET	SET nuclear oncogene
chr6_-_16761600	0.729	NM_000332 NM_001128164	ATXN1	ataxin 1
chr1_+_47489239	0.726	NM_178033	CYP4X1	cytochrome P450, family 4, subfamily X, polypeptide 1
chr7_-_156685621	0.722		LMBR1	limb region 1 homolog (mouse)
chr11_-_68518944	0.720	NM_001039656 NM_004923	MTL5	metallothionein-like 5, testis-specific (tesmin)
chr18_+_77155714	0.711	NM_006162 NM_172388 NM_172390	NFATC1	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
chr9_+_131451519	0.711		SET	SET nuclear oncogene
chr14_-_77494621	0.706		IRF2BPL	interferon regulatory factor 2 binding protein-like
chr2_-_43453724	0.705		ZFP36L2	zinc finger protein 36, C3H type-like 2
chr5_-_111093251	0.705	NM_001142479 NM_001142480 NM_001142478	C5orf13	chromosome 5 open reading frame 13
chr10_+_76586299	0.702	NM_012330	KAT6B	K(lysine) acetyltransferase 6B
chr17_-_47841468	0.702		FAM117A	family with sequence similarity 117, member A
chr17_-_58469577	0.697	NM_032582	USP32	ubiquitin specific peptidase 32
chr11_+_5617864	0.690	NM_001003818 NM_001198644 NM_001198645 NM_001003819	TRIM6 TRIM6-TRIM34	tripartite motif containing 6 TRIM6-TRIM34 readthrough
chr20_-_39317875	0.687	NM_005461	MAFB	v-maf musculoaponeurotic fibrosarcoma oncogene homolog B (avian)
chr12_+_83080621	0.683		TMTC2	transmembrane and tetratricopeptide repeat containing 2
chr15_-_82338459	0.678		MEX3B	mex-3 homolog B (C. elegans)
chr10_+_119301955	0.676	NM_001165924 NM_004098	EMX2	empty spiracles homeobox 2
chr7_-_27153490	0.674		HOXA3	homeobox A3
chr2_-_43453146	0.667		ZFP36L2	zinc finger protein 36, C3H type-like 2
chr11_-_71791734	0.666		NUMA1	nuclear mitotic apparatus protein 1
chr2_-_165477818	0.657		GRB14	growth factor receptor-bound protein 14
chr3_+_8543539	0.657		LMCD1	LIM and cysteine-rich domains 1
chr4_+_100871625	0.657		LOC256880	uncharacterized LOC256880
chr1_+_61547388	0.656	NM_001145512	NFIA	nuclear factor I/A
chr21_+_27107671	0.640		GABPA	GA binding protein transcription factor, alpha subunit 60kDa
chr1_+_35258598	0.632	NM_002060	GJA4	gap junction protein, alpha 4, 37kDa
chr19_-_31840118	0.630	NM_020856	TSHZ3	teashirt zinc finger homeobox 3
chr1_+_155147051	0.621		TRIM46	tripartite motif containing 46
chr16_+_69599868	0.620	NM_001113178 NM_006599 NM_138713 NM_138714 NM_173214 NM_173215	NFAT5	nuclear factor of activated T-cells 5, tonicity-responsive
chrX_+_73641084	0.620	NM_006517	SLC16A2	solute carrier family 16, member 2 (monocarboxylic acid transporter 8)
chr17_-_58469446	0.617		USP32	ubiquitin specific peptidase 32
chr10_-_126849556	0.615	NM_001083914	CTBP2	C-terminal binding protein 2
chr5_-_111093030	0.614	NM_001142482 NM_001142481	C5orf13	chromosome 5 open reading frame 13
chr7_+_114562140	0.614	NM_001166345 NM_001166346 NM_199072	MDFIC	MyoD family inhibitor domain containing
chr5_+_176560882	0.612		NSD1	nuclear receptor binding SET domain protein 1
chr20_-_45985411	0.612	NM_012408 NM_183047 NM_183048	ZMYND8	zinc finger, MYND-type containing 8
chr4_+_145567147	0.611	NM_022475	HHIP	hedgehog interacting protein
chr1_+_78470593	0.608	NM_007034	DNAJB4	DnaJ (Hsp40) homolog, subfamily B, member 4
chr15_-_69113089	0.607		ANP32A	acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
chr1_+_211432693	0.605	NM_001136223 NM_001136224 NM_001136225	RCOR3	REST corepressor 3
chr16_+_69599869	0.605		NFAT5	nuclear factor of activated T-cells 5, tonicity-responsive
chr5_-_111092918	0.600	NM_004772	C5orf13	chromosome 5 open reading frame 13
chr16_+_69600110	0.597		NFAT5	nuclear factor of activated T-cells 5, tonicity-responsive
chr21_-_27542919	0.593		APP	amyloid beta (A4) precursor protein
chr3_+_113465901	0.592		ATP6V1A	ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A
chr6_+_15245702	0.588		JARID2	jumonji, AT rich interactive domain 2
chr6_-_111136330	0.576		CDK19	cyclin-dependent kinase 19
chr8_-_22550708	0.571	NM_004430	EGR3	early growth response 3
chr1_-_92351476	0.568		TGFBR3	transforming growth factor, beta receptor III
chr9_+_2622099	0.565		VLDLR	very low density lipoprotein receptor
chr2_+_109150924	0.563		LIMS1	LIM and senescent cell antigen-like domains 1
chr12_+_53443834	0.562	NM_170754	TENC1	tensin like C1 domain containing phosphatase (tensin 2)
chr7_+_74072055	0.557		GTF2I	general transcription factor IIi
chr14_+_38678280	0.555		SSTR1	somatostatin receptor 1
chr10_+_102107256	0.554
chr9_-_84304378	0.554		TLE1	transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
chrX_-_101186976	0.554	NM_001011657	ZMAT1	zinc finger, matrin-type 1
chr3_+_110790460	0.551	NM_001243286 NM_015480	PVRL3	poliovirus receptor-related 3
chr9_+_2622052	0.548		VLDLR	very low density lipoprotein receptor
chr1_+_156863522	0.548	NM_001080471	PEAR1	platelet endothelial aggregation receptor 1
chr1_+_201617529	0.547		NAV1	neuron navigator 1
chr17_-_79008372	0.542		FLJ90757	uncharacterized LOC440465
chr10_+_8096772	0.538		GATA3	GATA binding protein 3
chrX_-_70473979	0.537	NM_201599	ZMYM3	zinc finger, MYM-type 3
chr4_+_41362750	0.536	NM_001112717 NM_001112718 NM_014988	LIMCH1	LIM and calponin homology domains 1
chr22_+_32439103	0.536		SLC5A1	solute carrier family 5 (sodium/glucose cotransporter), member 1
chr12_-_53893195	0.534	NM_001193511 NM_006301	MAP3K12	mitogen-activated protein kinase kinase kinase 12
chr5_+_139027955	0.532		CXXC5	CXXC finger protein 5
chr3_+_52444514	0.532	NM_016483 NM_173341	PHF7	PHD finger protein 7
chr17_-_49337370	0.528	NM_017643	MBTD1	mbt domain containing 1
chr20_-_31071384	0.527		C20orf112	chromosome 20 open reading frame 112
chr12_+_57943806	0.525		KIF5A	kinesin family member 5A
chr10_+_28822062	0.524
chr2_+_120517206	0.523	NM_002830	PTPN4	protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte)
chr2_+_48757063	0.522	NM_001198593	STON1-GTF2A1L	STON1-GTF2A1L readthrough
chr20_+_57226806	0.522		STX16	syntaxin 16
chr19_+_50094911	0.519	NM_020719	PRR12	proline rich 12
chr3_-_101231973	0.518	NM_001077203 NM_020654	SENP7	SUMO1/sentrin specific peptidase 7
chr1_+_87794576	0.515		LMO4	LIM domain only 4
chr17_+_63133501	0.513		RGS9	regulator of G-protein signaling 9
chr8_-_71316006	0.510	NM_006540	NCOA2	nuclear receptor coactivator 2
chr12_+_9067130	0.510	NM_004426	PHC1	polyhomeotic homolog 1 (Drosophila)
chr11_+_57365577	0.509	NM_001032295	SERPING1	serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
chr5_+_139027907	0.509		CXXC5	CXXC finger protein 5
chr12_+_75784878	0.507	NM_152436	GLIPR1L2	GLI pathogenesis-related 1 like 2
chr12_-_7281374	0.504	NM_031491	RBP5	retinol binding protein 5, cellular
chrX_-_70473941	0.504		ZMYM3	zinc finger, MYM-type 3
chr18_-_48723689	0.501		MEX3C	mex-3 homolog C (C. elegans)
chr10_+_21823573	0.501	NM_001195626	MLLT10	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
chr9_+_2622134	0.501		VLDLR	very low density lipoprotein receptor
chr17_+_65821625	0.500	NM_004459 NM_182641	BPTF	bromodomain PHD finger transcription factor
chr9_-_14313509	0.499		NFIB	nuclear factor I/B
chr10_-_35103894	0.498	NM_001184785 NM_001184786 NM_001184787 NM_001184788 NM_001184789 NM_001184790 NM_001184791 NM_001184792 NM_001184793 NM_001184794 NM_019619	PARD3	par-3 partitioning defective 3 homolog (C. elegans)
chr1_-_224622000	0.498	NM_001115113 NM_025160	WDR26	WD repeat domain 26
chr10_+_8096633	0.498	NM_001002295 NM_002051	GATA3	GATA binding protein 3
chr10_-_69835042	0.497	NM_015601 NM_022079	HERC4	hect domain and RLD 4
chr3_-_114866090	0.495	NM_015642	ZBTB20	zinc finger and BTB domain containing 20
chr2_-_75788027	0.493		FAM176A	family with sequence similarity 176, member A
chr10_+_28821699	0.492		WAC	WW domain containing adaptor with coiled-coil
chr4_-_102267952	0.492		PPP3CA	protein phosphatase 3, catalytic subunit, alpha isozyme
chr11_+_64107687	0.489	NM_032251	CCDC88B	coiled-coil domain containing 88B
chr20_-_31071187	0.488	NM_080616	C20orf112	chromosome 20 open reading frame 112
chr2_-_75788079	0.488	NM_001135032	FAM176A	family with sequence similarity 176, member A
chrX_-_62975005	0.485	NM_001173480 NM_015185	ARHGEF9	Cdc42 guanine nucleotide exchange factor (GEF) 9
chr16_+_53468373	0.482		RBL2	retinoblastoma-like 2 (p130)
chr1_+_201617449	0.482	NM_020443	NAV1	neuron navigator 1
chr4_-_102268626	0.482	NM_000944 NM_001130691 NM_001130692	PPP3CA	protein phosphatase 3, catalytic subunit, alpha isozyme
chr2_-_39664291	0.480		MAP4K3	mitogen-activated protein kinase kinase kinase kinase 3
chr1_+_16085245	0.478	NM_017556	FBLIM1	filamin binding LIM protein 1
chr4_-_114682340	0.476		CAMK2D	calcium/calmodulin-dependent protein kinase II delta
chr5_-_997408	0.476	NM_001242737	LOC100506688	uncharacterized LOC100506688
chr12_-_46384317	0.476		SCAF11	SR-related CTD-associated factor 11
chr1_+_200708604	0.474	NM_203459	CAMSAP2	calmodulin regulated spectrin-associated protein family, member 2
chr6_-_111804413	0.472	NM_002912	REV3L	REV3-like, catalytic subunit of DNA polymerase zeta (yeast)
chrX_-_62974987	0.472		ARHGEF9	Cdc42 guanine nucleotide exchange factor (GEF) 9
chr12_+_13349720	0.472		EMP1	epithelial membrane protein 1
chr12_+_57853917	0.471	NM_001160045 NM_001167609 NM_005269	GLI1	GLI family zinc finger 1
chr10_-_81205091	0.470	NM_153367	ZCCHC24	zinc finger, CCHC domain containing 24
chr6_+_7108184	0.468		RREB1	ras responsive element binding protein 1
chr7_-_150038689	0.467	NM_002889	RARRES2	retinoic acid receptor responder (tazarotene induced) 2
chr9_-_20622476	0.467	NM_004529	MLLT3	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
chr10_-_126849010	0.466		CTBP2	C-terminal binding protein 2

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.15	8.14e-29	GO:0065007	biological regulation
1.17	1.78e-28	GO:0050794	regulation of cellular process
1.16	2.77e-27	GO:0050789	regulation of biological process
1.09	7.42e-25	GO:0009987	cellular process
1.21	1.31e-17	GO:0023052	signaling
1.21	4.45e-16	GO:0080090	regulation of primary metabolic process
1.20	1.32e-15	GO:0031323	regulation of cellular metabolic process
1.24	7.75e-15	GO:0048518	positive regulation of biological process
1.25	1.50e-14	GO:0048522	positive regulation of cellular process
1.19	1.67e-14	GO:0019222	regulation of metabolic process
1.26	7.83e-14	GO:0048523	negative regulation of cellular process
1.24	2.96e-13	GO:0048519	negative regulation of biological process
1.20	4.82e-13	GO:0060255	regulation of macromolecule metabolic process
1.19	8.27e-13	GO:0007165	signal transduction
1.31	8.52e-13	GO:0009653	anatomical structure morphogenesis
1.24	4.31e-11	GO:0065008	regulation of biological quality
1.17	1.41e-10	GO:0032502	developmental process
1.29	1.46e-10	GO:0007399	nervous system development
1.27	2.29e-10	GO:0023051	regulation of signaling
1.14	2.29e-10	GO:0043170	macromolecule metabolic process
1.18	2.95e-10	GO:0048856	anatomical structure development
1.37	3.29e-10	GO:0022008	neurogenesis
1.38	4.28e-10	GO:0048699	generation of neurons
1.31	5.37e-10	GO:0009893	positive regulation of metabolic process
1.17	1.89e-09	GO:0071840	cellular component organization or biogenesis
1.14	2.41e-09	GO:0044260	cellular macromolecule metabolic process
1.22	2.55e-09	GO:0048869	cellular developmental process
1.36	2.63e-09	GO:0006351	transcription, DNA-dependent
1.19	3.51e-09	GO:0031326	regulation of cellular biosynthetic process
1.15	3.56e-09	GO:0051716	cellular response to stimulus
1.23	3.95e-09	GO:0030154	cell differentiation
1.31	4.19e-09	GO:0010604	positive regulation of macromolecule metabolic process
1.19	4.56e-09	GO:0009889	regulation of biosynthetic process
1.19	5.66e-09	GO:0051171	regulation of nitrogen compound metabolic process
1.40	7.76e-09	GO:0030182	neuron differentiation
1.30	8.36e-09	GO:0031325	positive regulation of cellular metabolic process
1.19	1.29e-08	GO:0019219	regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.20	1.54e-08	GO:2000112	regulation of cellular macromolecule biosynthetic process
1.36	2.00e-08	GO:0051128	regulation of cellular component organization
1.41	2.02e-08	GO:0007167	enzyme linked receptor protein signaling pathway
1.16	2.32e-08	GO:0007275	multicellular organismal development
1.16	2.43e-08	GO:0016043	cellular component organization
1.18	2.61e-08	GO:0048731	system development
1.27	2.87e-08	GO:0009966	regulation of signal transduction
1.19	3.09e-08	GO:0010556	regulation of macromolecule biosynthetic process
1.41	4.64e-08	GO:0032989	cellular component morphogenesis
1.10	5.47e-08	GO:0044238	primary metabolic process
1.09	8.58e-08	GO:0008152	metabolic process
1.18	1.67e-07	GO:0010468	regulation of gene expression
1.10	1.79e-07	GO:0044237	cellular metabolic process
1.43	1.94e-07	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
1.32	2.34e-07	GO:0048468	cell development
1.32	2.71e-07	GO:0010605	negative regulation of macromolecule metabolic process
1.20	2.75e-07	GO:0051252	regulation of RNA metabolic process
1.31	3.27e-07	GO:0009892	negative regulation of metabolic process
1.25	3.37e-07	GO:0065009	regulation of molecular function
1.43	4.49e-07	GO:0000904	cell morphogenesis involved in differentiation
1.39	6.19e-07	GO:0000902	cell morphogenesis
1.21	6.93e-07	GO:0048583	regulation of response to stimulus
1.28	9.40e-07	GO:0051246	regulation of protein metabolic process
1.36	1.25e-06	GO:0045595	regulation of cell differentiation
1.34	1.32e-06	GO:0010557	positive regulation of macromolecule biosynthetic process
1.31	1.45e-06	GO:0031324	negative regulation of cellular metabolic process
1.30	1.49e-06	GO:0006357	regulation of transcription from RNA polymerase II promoter
1.17	1.74e-06	GO:0071841	cellular component organization or biogenesis at cellular level
1.21	2.03e-06	GO:0006464	protein modification process
1.19	2.08e-06	GO:0006355	regulation of transcription, DNA-dependent
1.31	2.87e-06	GO:0009891	positive regulation of biosynthetic process
1.61	4.25e-06	GO:0048011	nerve growth factor receptor signaling pathway
1.31	4.59e-06	GO:0031328	positive regulation of cellular biosynthetic process
1.41	5.20e-06	GO:0031175	neuron projection development
1.38	6.16e-06	GO:0048666	neuron development
1.59	7.06e-06	GO:0051129	negative regulation of cellular component organization
1.17	7.47e-06	GO:0071842	cellular component organization at cellular level
1.28	7.99e-06	GO:0032268	regulation of cellular protein metabolic process
1.24	8.81e-06	GO:0035556	intracellular signal transduction
1.28	1.57e-05	GO:0032879	regulation of localization
1.18	1.60e-05	GO:0042221	response to chemical stimulus
1.31	1.67e-05	GO:0031399	regulation of protein modification process
1.34	2.08e-05	GO:0010628	positive regulation of gene expression
1.41	3.40e-05	GO:0048812	neuron projection morphogenesis
1.34	4.36e-05	GO:2000113	negative regulation of cellular macromolecule biosynthetic process
1.34	4.87e-05	GO:0045893	positive regulation of transcription, DNA-dependent
1.48	4.90e-05	GO:0032870	cellular response to hormone stimulus
1.18	5.81e-05	GO:0043412	macromolecule modification
1.13	6.05e-05	GO:0051179	localization
1.33	6.12e-05	GO:0030030	cell projection organization
1.28	6.17e-05	GO:0050793	regulation of developmental process
1.19	6.44e-05	GO:0007166	cell surface receptor linked signaling pathway
1.40	6.90e-05	GO:0048667	cell morphogenesis involved in neuron differentiation
1.46	7.62e-05	GO:0071495	cellular response to endogenous stimulus
1.33	7.63e-05	GO:0001932	regulation of protein phosphorylation
1.32	7.74e-05	GO:0051254	positive regulation of RNA metabolic process
1.37	8.05e-05	GO:0032990	cell part morphogenesis
1.30	8.57e-05	GO:0045935	positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.30	8.75e-05	GO:0051173	positive regulation of nitrogen compound metabolic process
1.37	1.01e-04	GO:0048858	cell projection morphogenesis
1.32	1.05e-04	GO:0031327	negative regulation of cellular biosynthetic process
1.31	1.06e-04	GO:0009890	negative regulation of biosynthetic process
1.24	1.19e-04	GO:0050790	regulation of catalytic activity
1.32	1.23e-04	GO:0010558	negative regulation of macromolecule biosynthetic process
1.32	1.45e-04	GO:0042325	regulation of phosphorylation
1.40	1.57e-04	GO:0007409	axonogenesis
1.47	1.58e-04	GO:0051130	positive regulation of cellular component organization
1.33	1.61e-04	GO:0010629	negative regulation of gene expression
1.25	1.68e-04	GO:0010646	regulation of cell communication
1.22	2.24e-04	GO:0051239	regulation of multicellular organismal process
1.31	2.25e-04	GO:0019220	regulation of phosphate metabolic process
1.31	2.25e-04	GO:0051174	regulation of phosphorus metabolic process
1.25	2.85e-04	GO:0032774	RNA biosynthetic process
1.19	2.95e-04	GO:0016070	RNA metabolic process
1.14	3.47e-04	GO:0006810	transport
1.25	3.81e-04	GO:0006793	phosphorus metabolic process
1.25	3.81e-04	GO:0006796	phosphate metabolic process
1.29	4.08e-04	GO:0006468	protein phosphorylation
1.14	4.46e-04	GO:0006139	nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.32	4.47e-04	GO:0009725	response to hormone stimulus
1.13	4.59e-04	GO:0051234	establishment of localization
1.25	4.62e-04	GO:0042127	regulation of cell proliferation
1.26	4.87e-04	GO:0008219	cell death
1.38	5.52e-04	GO:0008285	negative regulation of cell proliferation
1.26	5.98e-04	GO:0016265	death
1.31	6.24e-04	GO:0009057	macromolecule catabolic process
1.88	7.11e-04	GO:0007015	actin filament organization
1.43	7.66e-04	GO:0007411	axon guidance
1.27	8.50e-04	GO:0044093	positive regulation of molecular function
1.35	9.36e-04	GO:0072358	cardiovascular system development
1.35	9.36e-04	GO:0072359	circulatory system development
1.44	1.46e-03	GO:0006366	transcription from RNA polymerase II promoter
1.29	1.57e-03	GO:0009719	response to endogenous stimulus
1.33	1.61e-03	GO:0045892	negative regulation of transcription, DNA-dependent
1.24	1.87e-03	GO:0009605	response to external stimulus
1.32	2.45e-03	GO:0051253	negative regulation of RNA metabolic process
1.16	2.47e-03	GO:0048513	organ development
1.35	2.73e-03	GO:0032583	regulation of gene-specific transcription
1.28	2.74e-03	GO:0043085	positive regulation of catalytic activity
1.25	2.84e-03	GO:0016310	phosphorylation
1.29	3.51e-03	GO:0071310	cellular response to organic substance
1.38	4.04e-03	GO:0007420	brain development
1.30	4.65e-03	GO:0042060	wound healing
1.29	5.95e-03	GO:0051172	negative regulation of nitrogen compound metabolic process
1.48	6.27e-03	GO:0071375	cellular response to peptide hormone stimulus
1.37	6.28e-03	GO:0016568	chromatin modification
1.31	6.41e-03	GO:0044092	negative regulation of molecular function
1.36	6.45e-03	GO:0000122	negative regulation of transcription from RNA polymerase II promoter
1.29	6.86e-03	GO:0045934	negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.93	7.24e-03	GO:0050680	negative regulation of epithelial cell proliferation
1.17	7.34e-03	GO:0006996	organelle organization
1.39	8.28e-03	GO:0033043	regulation of organelle organization
1.41	9.25e-03	GO:0030029	actin filament-based process
1.44	9.40e-03	GO:0030036	actin cytoskeleton organization
1.44	9.61e-03	GO:0051248	negative regulation of protein metabolic process
1.22	9.72e-03	GO:0007154	cell communication
1.25	9.73e-03	GO:0016192	vesicle-mediated transport
1.26	1.05e-02	GO:0006915	apoptosis
1.16	1.09e-02	GO:0010467	gene expression
1.26	1.28e-02	GO:0051049	regulation of transport
1.25	1.42e-02	GO:0012501	programmed cell death
1.23	1.55e-02	GO:0042592	homeostatic process
1.29	1.55e-02	GO:0050878	regulation of body fluid levels
1.61	1.55e-02	GO:0010639	negative regulation of organelle organization
1.19	1.57e-02	GO:0010033	response to organic substance
1.44	1.74e-02	GO:0032269	negative regulation of cellular protein metabolic process
1.30	1.78e-02	GO:0051338	regulation of transferase activity
1.13	1.81e-02	GO:0044267	cellular protein metabolic process
1.31	1.83e-02	GO:0045944	positive regulation of transcription from RNA polymerase II promoter
1.30	1.91e-02	GO:0007599	hemostasis
1.41	2.36e-02	GO:0001568	blood vessel development
1.11	2.36e-02	GO:0006807	nitrogen compound metabolic process
1.14	2.37e-02	GO:0090304	nucleic acid metabolic process
1.11	2.39e-02	GO:0019538	protein metabolic process
1.24	2.52e-02	GO:2000026	regulation of multicellular organismal development
1.30	2.62e-02	GO:0043549	regulation of kinase activity
1.25	2.62e-02	GO:0009790	embryo development
1.31	2.71e-02	GO:0045859	regulation of protein kinase activity
1.60	2.84e-02	GO:0050890	cognition
1.33	2.85e-02	GO:0009968	negative regulation of signal transduction
1.93	2.98e-02	GO:0070848	response to growth factor stimulus
1.36	3.10e-02	GO:0045597	positive regulation of cell differentiation
1.39	3.36e-02	GO:0001944	vasculature development
1.29	3.67e-02	GO:0007417	central nervous system development
1.34	3.79e-02	GO:0030163	protein catabolic process
1.56	4.07e-02	GO:0016055	Wnt receptor signaling pathway
1.22	4.31e-02	GO:0040011	locomotion
1.29	4.39e-02	GO:0007596	blood coagulation
1.29	4.39e-02	GO:0050817	coagulation

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.08	1.45e-17	GO:0044424	intracellular part
1.07	6.84e-16	GO:0005622	intracellular
1.10	1.73e-13	GO:0005737	cytoplasm
1.14	2.41e-13	GO:0005634	nucleus
1.09	6.72e-12	GO:0043227	membrane-bounded organelle
1.09	8.60e-12	GO:0043231	intracellular membrane-bounded organelle
1.08	2.22e-11	GO:0043226	organelle
1.08	4.33e-11	GO:0043229	intracellular organelle
1.22	5.66e-10	GO:0005829	cytosol
1.23	3.78e-09	GO:0031981	nuclear lumen
1.20	1.86e-08	GO:0044428	nuclear part
1.49	2.17e-08	GO:0043005	neuron projection
1.18	5.80e-07	GO:0043233	organelle lumen
1.03	1.17e-06	GO:0044464	cell part
1.03	1.28e-06	GO:0005623	cell
1.17	2.41e-06	GO:0070013	intracellular organelle lumen
1.17	3.96e-06	GO:0031974	membrane-enclosed lumen
1.33	1.85e-05	GO:0030054	cell junction
1.22	2.80e-05	GO:0005654	nucleoplasm
1.26	6.52e-05	GO:0042995	cell projection
1.94	1.26e-04	GO:0030427	site of polarized growth
1.27	1.30e-04	GO:0031982	vesicle
1.37	1.38e-04	GO:0045202	synapse
1.15	1.73e-04	GO:0044459	plasma membrane part
1.55	2.42e-04	GO:0031252	cell leading edge
1.91	4.77e-04	GO:0030426	growth cone
1.08	4.77e-04	GO:0044444	cytoplasmic part
1.58	6.37e-04	GO:0005912	adherens junction
1.25	9.19e-04	GO:0031410	cytoplasmic vesicle
1.21	1.68e-03	GO:0005794	Golgi apparatus
1.44	1.72e-03	GO:0016323	basolateral plasma membrane
1.68	1.78e-03	GO:0019717	synaptosome
1.12	2.19e-03	GO:0043234	protein complex
1.74	2.27e-03	GO:0030027	lamellipodium
1.08	2.29e-03	GO:0044446	intracellular organelle part
1.74	2.50e-03	GO:0000790	nuclear chromatin
1.52	2.57e-03	GO:0070161	anchoring junction
1.08	2.60e-03	GO:0044422	organelle part
1.45	3.87e-03	GO:0000228	nuclear chromosome
1.63	4.40e-03	GO:0030055	cell-substrate junction
1.65	4.60e-03	GO:0005925	focal adhesion
1.23	5.43e-03	GO:0031988	membrane-bounded vesicle
1.63	5.50e-03	GO:0005924	cell-substrate adherens junction
1.23	8.22e-03	GO:0016023	cytoplasmic membrane-bounded vesicle
1.35	8.31e-03	GO:0044433	cytoplasmic vesicle part
1.96	9.28e-03	GO:0000792	heterochromatin
1.48	1.38e-02	GO:0030136	clathrin-coated vesicle
1.32	1.43e-02	GO:0048471	perinuclear region of cytoplasm
1.46	1.54e-02	GO:0030424	axon
1.96	1.90e-02	GO:0008287	protein serine/threonine phosphatase complex
1.42	2.17e-02	GO:0030135	coated vesicle
1.43	2.72e-02	GO:0030425	dendrite
1.11	2.82e-02	GO:0043228	non-membrane-bounded organelle
1.11	2.82e-02	GO:0043232	intracellular non-membrane-bounded organelle
1.24	2.87e-02	GO:0044431	Golgi apparatus part
1.33	4.29e-02	GO:0015629	actin cytoskeleton

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.21	9.71e-51	GO:0005515	protein binding
1.09	1.03e-30	GO:0005488	binding
1.43	3.13e-11	GO:0043565	sequence-specific DNA binding
1.47	1.50e-08	GO:0019904	protein domain specific binding
1.30	8.64e-08	GO:0030528	transcription regulator activity
1.30	9.52e-08	GO:0001071	nucleic acid binding transcription factor activity
1.30	9.52e-08	GO:0003700	sequence-specific DNA binding transcription factor activity
1.40	2.22e-07	GO:0008092	cytoskeletal protein binding
1.29	4.08e-05	GO:0019899	enzyme binding
1.47	4.08e-05	GO:0008134	transcription factor binding
1.53	1.77e-04	GO:0000975	regulatory region DNA binding
1.53	1.77e-04	GO:0001067	regulatory region nucleic acid binding
1.53	1.77e-04	GO:0044212	transcription regulatory region DNA binding
1.54	2.85e-04	GO:0010843	promoter binding
1.41	3.55e-04	GO:0003779	actin binding
1.27	6.51e-04	GO:0016773	phosphotransferase activity, alcohol group as acceptor
1.40	1.46e-03	GO:0016564	transcription repressor activity
2.01	2.18e-03	GO:0019208	phosphatase regulator activity
1.35	3.73e-03	GO:0000988	protein binding transcription factor activity
1.35	3.73e-03	GO:0000989	transcription factor binding transcription factor activity
1.34	5.09e-03	GO:0003712	transcription cofactor activity
1.22	1.38e-02	GO:0016301	kinase activity
1.20	1.46e-02	GO:0005102	receptor binding
1.34	2.47e-02	GO:0016563	transcription activator activity
2.98	2.73e-02	GO:0043425	bHLH transcription factor binding
1.25	2.77e-02	GO:0004672	protein kinase activity
1.19	4.00e-02	GO:0030234	enzyme regulator activity