Motif ID: MZF1.p2

Z-value: 1.147


Transcription factors associated with MZF1.p2:

Gene SymbolEntrez IDGene Name
MZF1 7593 myeloid zinc finger 1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.p-valuePlot
MZF1chr19_-_59084735,
chr19_-_59084630		0.331.0e-01Click!


Activity profile for motif MZF1.p2.

activity profile for motif MZF1.p2


Sorted Z-values histogram for motif MZF1.p2

Sorted Z-values for motif MZF1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of MZF1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr1_+_211432726 4.128 RCOR3
REST corepressor 3
chr1_+_211432732 2.884 RCOR3
REST corepressor 3
chr2_+_48757292 2.594 NM_001198595
NM_006873
 STON1

stonin 1

chr11_-_68518910 1.926 MTL5
metallothionein-like 5, testis-specific (tesmin)
chr1_+_164528586 1.782 NM_001204961
NM_001204963
NM_002585
 PBX1


pre-B-cell leukemia homeobox 1


chr18_-_22932109 1.695 NM_015461
 ZNF521
zinc finger protein 521
chr1_+_61547625 1.550 NM_001134673
NM_005595
 NFIA

nuclear factor I/A

chr5_+_139028483 1.536 CXXC5
CXXC finger protein 5
chr18_-_22931970 1.491 ZNF521
zinc finger protein 521
chr5_-_88179278 1.471 NM_001193350
NM_002397
 MEF2C

myocyte enhancer factor 2C

chr11_-_73309090 1.462 NM_015159
 FAM168A
family with sequence similarity 168, member A
chrX_-_119694871 1.377 CUL4B
cullin 4B
chrX_-_119694719 1.375 NM_001079872
 CUL4B
cullin 4B
chr5_-_73936299 1.313 ENC1
ectodermal-neural cortex 1 (with BTB-like domain)
chr2_+_182756665 1.307 SSFA2
sperm specific antigen 2
chrX_-_119694492 1.275 CUL4B
cullin 4B
chr18_-_22930826 1.188


chr2_-_217236666 1.185 NM_020814
 MARCH4
membrane-associated ring finger (C3HC4) 4
chr5_-_88178964 1.174 MEF2C
myocyte enhancer factor 2C
chr2_-_165477986 1.158 GRB14
growth factor receptor-bound protein 14

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 186 entries
enrichment   p-value GO term description
1.93 7.24e-03 GO:0050680 negative regulation of epithelial cell proliferation
1.93 2.98e-02 GO:0070848 response to growth factor stimulus
1.88 7.11e-04 GO:0007015 actin filament organization
1.61 4.25e-06 GO:0048011 nerve growth factor receptor signaling pathway
1.61 1.55e-02 GO:0010639 negative regulation of organelle organization
1.60 2.84e-02 GO:0050890 cognition
1.59 7.06e-06 GO:0051129 negative regulation of cellular component organization
1.56 4.07e-02 GO:0016055 Wnt receptor signaling pathway
1.48 4.90e-05 GO:0032870 cellular response to hormone stimulus
1.48 6.27e-03 GO:0071375 cellular response to peptide hormone stimulus
1.47 1.58e-04 GO:0051130 positive regulation of cellular component organization
1.46 7.62e-05 GO:0071495 cellular response to endogenous stimulus
1.44 1.46e-03 GO:0006366 transcription from RNA polymerase II promoter
1.44 9.40e-03 GO:0030036 actin cytoskeleton organization
1.44 9.61e-03 GO:0051248 negative regulation of protein metabolic process
1.44 1.74e-02 GO:0032269 negative regulation of cellular protein metabolic process
1.43 1.94e-07 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
1.43 4.49e-07 GO:0000904 cell morphogenesis involved in differentiation
1.43 7.66e-04 GO:0007411 axon guidance
1.41 2.02e-08 GO:0007167 enzyme linked receptor protein signaling pathway

Gene overrepresentation in compartment category:

Showing 1 to 20 of 56 entries
enrichment   p-value GO term description
1.96 9.28e-03 GO:0000792 heterochromatin
1.96 1.90e-02 GO:0008287 protein serine/threonine phosphatase complex
1.94 1.26e-04 GO:0030427 site of polarized growth
1.91 4.77e-04 GO:0030426 growth cone
1.74 2.27e-03 GO:0030027 lamellipodium
1.74 2.50e-03 GO:0000790 nuclear chromatin
1.68 1.78e-03 GO:0019717 synaptosome
1.65 4.60e-03 GO:0005925 focal adhesion
1.63 4.40e-03 GO:0030055 cell-substrate junction
1.63 5.50e-03 GO:0005924 cell-substrate adherens junction
1.58 6.37e-04 GO:0005912 adherens junction
1.55 2.42e-04 GO:0031252 cell leading edge
1.52 2.57e-03 GO:0070161 anchoring junction
1.49 2.17e-08 GO:0043005 neuron projection
1.48 1.38e-02 GO:0030136 clathrin-coated vesicle
1.46 1.54e-02 GO:0030424 axon
1.45 3.87e-03 GO:0000228 nuclear chromosome
1.44 1.72e-03 GO:0016323 basolateral plasma membrane
1.43 2.72e-02 GO:0030425 dendrite
1.42 2.17e-02 GO:0030135 coated vesicle

Gene overrepresentation in function category:

Showing 1 to 20 of 27 entries
enrichment   p-value GO term description
2.98 2.73e-02 GO:0043425 bHLH transcription factor binding
2.01 2.18e-03 GO:0019208 phosphatase regulator activity
1.54 2.85e-04 GO:0010843 promoter binding
1.53 1.77e-04 GO:0000975 regulatory region DNA binding
1.53 1.77e-04 GO:0001067 regulatory region nucleic acid binding
1.53 1.77e-04 GO:0044212 transcription regulatory region DNA binding
1.47 1.50e-08 GO:0019904 protein domain specific binding
1.47 4.08e-05 GO:0008134 transcription factor binding
1.43 3.13e-11 GO:0043565 sequence-specific DNA binding
1.41 3.55e-04 GO:0003779 actin binding
1.40 2.22e-07 GO:0008092 cytoskeletal protein binding
1.40 1.46e-03 GO:0016564 transcription repressor activity
1.35 3.73e-03 GO:0000988 protein binding transcription factor activity
1.35 3.73e-03 GO:0000989 transcription factor binding transcription factor activity
1.34 5.09e-03 GO:0003712 transcription cofactor activity
1.34 2.47e-02 GO:0016563 transcription activator activity
1.30 8.64e-08 GO:0030528 transcription regulator activity
1.30 9.52e-08 GO:0001071 nucleic acid binding transcription factor activity
1.30 9.52e-08 GO:0003700 sequence-specific DNA binding transcription factor activity
1.29 4.08e-05 GO:0019899 enzyme binding