Motif ID: NANOG{mouse}.p2

Z-value: 1.156


Transcription factors associated with NANOG{mouse}.p2:

Gene SymbolEntrez IDGene Name
NANOG 79923 Nanog homeobox

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.p-valuePlot
NANOGchr12_+_7941994-0.414.0e-02Click!


Activity profile for motif NANOG{mouse}.p2.

activity profile for motif NANOG{mouse}.p2


Sorted Z-values histogram for motif NANOG{mouse}.p2

Sorted Z-values for motif NANOG{mouse}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NANOG{mouse}.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr13_+_58205943 4.373 PCDH17
protocadherin 17
chr8_-_9008138 4.159 NM_024607
PPP1R3B
protein phosphatase 1, regulatory subunit 3B
chr19_-_13213973 2.991 NM_005583
LYL1
lymphoblastic leukemia derived sequence 1
chr19_-_13213513 2.753 LYL1
lymphoblastic leukemia derived sequence 1
chr19_-_13213669 2.719 LYL1
lymphoblastic leukemia derived sequence 1
chr2_+_45878912 2.577 NM_005400
PRKCE
protein kinase C, epsilon
chr4_-_16900256 2.569 LDB2
LIM domain binding 2
chr3_+_32148136 2.256 GPD1L
glycerol-3-phosphate dehydrogenase 1-like
chr6_+_148663728 2.221 NM_015278
SASH1
SAM and SH3 domain containing 1
chr12_+_53442732 2.159 NM_015319
TENC1
tensin like C1 domain containing phosphatase (tensin 2)
chr12_-_53901371 2.059 NM_003717
NPFF
neuropeptide FF-amide peptide precursor
chr3_-_93692592 2.033 PROS1
protein S (alpha)
chr14_-_91526912 2.004 NM_004755
NM_182398
RPS6KA5

ribosomal protein S6 kinase, 90kDa, polypeptide 5

chr7_+_150382783 1.982 NM_015660
GIMAP2
GTPase, IMAP family member 2
chr3_-_93692898 1.919 NM_000313
PROS1
protein S (alpha)
chr12_+_57828457 1.908 NM_005538
INHBC
inhibin, beta C
chr1_+_210406194 1.901 NM_019605
SERTAD4
SERTA domain containing 4
chr2_+_176994421 1.839 NM_001199747
NM_001199746
NM_019558
HOXD8


homeobox D8


chr4_-_16900028 1.748 LDB2
LIM domain binding 2
chr11_+_7618416 1.695 PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr10_+_97889467 1.683 NM_014803
ZNF518A
zinc finger protein 518A
chr3_-_122512526 1.656 NM_024610
HSPBAP1
HSPB (heat shock 27kDa) associated protein 1
chr9_+_137979513 1.628 OLFM1
olfactomedin 1
chr2_-_188312872 1.514 NM_005795
CALCRL
calcitonin receptor-like
chr13_-_101327102 1.510 NM_001079669
NM_032813
TMTC4

transmembrane and tetratricopeptide repeat containing 4

chr4_-_16900348 1.506 NM_001130834
NM_001290
LDB2

LIM domain binding 2

chr9_-_126030792 1.464 NM_018387
STRBP
spermatid perinuclear RNA binding protein
chr1_-_231114596 1.404 TTC13
tetratricopeptide repeat domain 13
chr1_-_231114580 1.388 TTC13
tetratricopeptide repeat domain 13
chr11_-_27743604 1.377 NM_170731
BDNF
brain-derived neurotrophic factor
chr9_-_126030854 1.372 NM_001171137
STRBP
spermatid perinuclear RNA binding protein
chr3_-_56809594 1.372 NM_001128616
ARHGEF3
Rho guanine nucleotide exchange factor (GEF) 3
chr18_-_46469118 1.352 NM_001190823
SMAD7
SMAD family member 7
chr11_-_102714240 1.307 NM_002422
MMP3
matrix metallopeptidase 3 (stromelysin 1, progelatinase)
chr16_+_640056 1.302 NM_001172665
NM_001172666
RAB40C

RAB40C, member RAS oncogene family

chr12_-_123187842 1.295 NM_177551
HCAR2
hydroxycarboxylic acid receptor 2
chr3_-_49851217 1.283 UBA7
ubiquitin-like modifier activating enzyme 7
chr20_+_58508818 1.281 NM_001190826
C20orf177
chromosome 20 open reading frame 177
chr13_-_45010974 1.248 TSC22D1
TSC22 domain family, member 1
chrX_-_133931146 1.173 NM_001166599
NM_001166600
NM_001170757
FAM122B


family with sequence similarity 122B


chr13_-_45010994 1.156 TSC22D1
TSC22 domain family, member 1
chr11_+_121461070 1.155 SORL1
sortilin-related receptor, L(DLR class) A repeats containing
chr2_+_203499819 1.154 NM_173511
FAM117B
family with sequence similarity 117, member B
chr6_-_107077167 1.104 NM_032730
RTN4IP1
reticulon 4 interacting protein 1
chr16_+_640172 1.097 NM_021168
RAB40C
RAB40C, member RAS oncogene family
chrX_+_138612894 1.090 NM_000133
F9
coagulation factor IX
chr4_-_140201339 1.072 NM_032623
C4orf49
chromosome 4 open reading frame 49
chr22_-_39548448 1.072 NM_175709
CBX7
chromobox homolog 7
chr1_-_173837122 1.067 GAS5
growth arrest-specific 5 (non-protein coding)
chrX_+_149613719 1.055 NM_001177466
NM_005491
MAMLD1

mastermind-like domain containing 1

chr19_+_39897457 1.035 NM_003407
ZFP36
zinc finger protein 36, C3H type, homolog (mouse)
chr13_-_45010937 1.035 TSC22D1
TSC22 domain family, member 1
chr6_+_148663953 1.030 SASH1
SAM and SH3 domain containing 1
chr13_+_53035227 1.029 CKAP2
cytoskeleton associated protein 2
chr1_-_231114617 1.029 NM_001122835
NM_024525
TTC13

tetratricopeptide repeat domain 13

chr20_+_37555055 1.023 FAM83D
family with sequence similarity 83, member D
chr12_-_56727446 1.011 NM_001127460
PAN2
PAN2 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)
chr6_-_20212628 0.995 NM_001080480
MBOAT1
membrane bound O-acyltransferase domain containing 1
chr9_+_79115548 0.994 NM_001097636
GCNT1
glucosaminyl (N-acetyl) transferase 1, core 2
chr16_+_640091 0.966 RAB40C
RAB40C, member RAS oncogene family
chr2_-_97405775 0.965 LMAN2L
lectin, mannose-binding 2-like
chr10_-_105238996 0.960 NM_001129742
CALHM3
calcium homeostasis modulator 3
chr12_-_123201319 0.957 NM_006018
HCAR3
hydroxycarboxylic acid receptor 3
chr21_-_47704166 0.952 MCM3AP
minichromosome maintenance complex component 3 associated protein
chr4_+_186131283 0.949 NM_031953
SNX25
sorting nexin 25
chr10_+_129845806 0.947 NM_130435
PTPRE
protein tyrosine phosphatase, receptor type, E
chr7_+_86974928 0.944 NM_001143935
NM_001243745
NM_021151
CROT


carnitine O-octanoyltransferase


chr12_-_31743822 0.939 NM_144973
DENND5B
DENN/MADD domain containing 5B
chrX_-_62570968 0.930 NM_001012968
SPIN4
spindlin family, member 4
chr17_-_34417386 0.926 NM_002983
CCL3
chemokine (C-C motif) ligand 3
chr11_-_2906960 0.921 NM_000076
NM_001122630
NM_001122631
CDKN1C


cyclin-dependent kinase inhibitor 1C (p57, Kip2)


chr6_-_2840683 0.916 SERPINB1
serpin peptidase inhibitor, clade B (ovalbumin), member 1
chr2_-_97405799 0.914 NM_001142292
NM_030805
LMAN2L

lectin, mannose-binding 2-like

chr19_-_54327428 0.901 NM_144687
NLRP12
NLR family, pyrin domain containing 12
chr18_+_77623667 0.884 NM_012283
KCNG2
potassium voltage-gated channel, subfamily G, member 2
chr1_-_147245483 0.883 NM_005266
GJA5
gap junction protein, alpha 5, 40kDa
chr5_+_42548314 0.879 NM_001242403
GHR
growth hormone receptor
chr14_-_23285011 0.862 NM_001126105
SLC7A7
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr4_-_16077740 0.859 NM_001145849
NM_001145850
NM_001145851
NM_001145852
NM_006017
PROM1




prominin 1




chrX_-_118827116 0.833 SEPT6
septin 6
chr6_+_87865261 0.826 NM_015021
ZNF292
zinc finger protein 292
chr8_-_19540093 0.824 NM_018371
CSGALNACT1
chondroitin sulfate N-acetylgalactosaminyltransferase 1
chr3_-_49851356 0.823 NM_003335
UBA7
ubiquitin-like modifier activating enzyme 7
chr5_-_89770110 0.818 MBLAC2
metallo-beta-lactamase domain containing 2
chr9_-_35748875 0.803 GBA2
glucosidase, beta (bile acid) 2
chr16_+_639668 0.783 NM_001172664
RAB40C
RAB40C, member RAS oncogene family
chr17_-_71088820 0.778 SLC39A11
solute carrier family 39 (metal ion transporter), member 11
chr10_+_97889655 0.778 ZNF518A
zinc finger protein 518A
chr17_+_72744775 0.770 SLC9A3R1
solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1
chr7_+_102715616 0.765 ARMC10
armadillo repeat containing 10
chr6_+_136172802 0.758 NM_018945
PDE7B
phosphodiesterase 7B
chr16_-_75301950 0.758 NM_001170715
BCAR1
breast cancer anti-estrogen resistance 1
chr12_-_25055228 0.752 NM_001178094
BCAT1
branched chain amino-acid transaminase 1, cytosolic
chr13_-_48987017 0.750 LPAR6
lysophosphatidic acid receptor 6
chr9_+_139560193 0.739 NM_201446
EGFL7
EGF-like-domain, multiple 7
chr22_+_27017927 0.737 NM_001886
CRYBA4
crystallin, beta A4
chr16_-_70719854 0.736 NM_138383
MTSS1L
metastasis suppressor 1-like
chr2_-_198540583 0.734 NM_144629
RFTN2
raftlin family member 2
chr16_-_71323090 0.725 NM_001099642
NM_018348
FTSJD1

FtsJ methyltransferase domain containing 1

chr3_+_132379130 0.701 NM_024818
UBA5
ubiquitin-like modifier activating enzyme 5
chrX_-_133792497 0.696 NM_021796
PLAC1
placenta-specific 1
chr3_-_15900928 0.694 NM_015199
ANKRD28
ankyrin repeat domain 28
chr7_-_86974693 0.690 TP53TG1
TP53 target 1 (non-protein coding)
chr17_+_48172508 0.689 NM_001199900
NM_002611
NM_001199899
PDK2


pyruvate dehydrogenase kinase, isozyme 2


chr16_+_31494438 0.684 NM_003041
SLC5A2
solute carrier family 5 (sodium/glucose cotransporter), member 2
chr2_-_68547018 0.682 NM_001111101
NM_015463
CNRIP1

cannabinoid receptor interacting protein 1

chr20_+_37554954 0.664 NM_030919
FAM83D
family with sequence similarity 83, member D
chr5_+_139493689 0.662 NM_005859
PURA
purine-rich element binding protein A
chr6_+_90272036 0.640 NM_001242811
ANKRD6
ankyrin repeat domain 6
chr19_-_38916801 0.632 NM_001146202
NM_001146203
NM_001146204
NM_001146205
NM_001146206
NM_001146207
NM_170604
RASGRP4






RAS guanyl releasing protein 4






chr1_+_155146270 0.631 TRIM46
tripartite motif containing 46
chr6_-_99395807 0.622 NM_012160
FBXL4
F-box and leucine-rich repeat protein 4
chrX_-_118827060 0.620 SEPT6
septin 6
chr16_+_8806825 0.618 NM_000663
ABAT
4-aminobutyrate aminotransferase
chr3_-_52567809 0.618 NT5DC2
5'-nucleotidase domain containing 2
chr16_-_3085541 0.609 NM_001103175
CCDC64B
coiled-coil domain containing 64B
chr22_+_45148437 0.608 NM_001017526
NM_001198726
NM_181335
ARHGAP8


Rho GTPase activating protein 8


chr2_-_183902747 0.605 NCKAP1
NCK-associated protein 1
chr5_+_61874561 0.600 NM_181506
LRRC70
leucine rich repeat containing 70
chr17_+_72744794 0.590 SLC9A3R1
solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1
chr10_-_17171789 0.590 NM_001081
CUBN
cubilin (intrinsic factor-cobalamin receptor)
chr17_-_7387513 0.584 NM_020899
ZBTB4
zinc finger and BTB domain containing 4
chr13_-_48987247 0.577 LPAR6
lysophosphatidic acid receptor 6
chr14_+_21156922 0.577 NM_001097577
NM_194431
ANG
RNASE4
angiogenin, ribonuclease, RNase A family, 5
ribonuclease, RNase A family, 4
chr2_-_240322692 0.566 HDAC4
histone deacetylase 4
chr14_-_100772774 0.560 NM_001039355
SLC25A29
solute carrier family 25, member 29
chr13_-_101327027 0.558 TMTC4
transmembrane and tetratricopeptide repeat containing 4
chr17_+_45772629 0.557 NM_014726
TBKBP1
TBK1 binding protein 1
chr10_+_83637442 0.544 NM_001165973
NRG3
neuregulin 3
chr1_+_161632904 0.543 NM_001002273
NM_001002274
NM_001002275
NM_001190828
NM_004001
FCGR2B




FCGR2C
Fc fragment of IgG, low affinity IIb, receptor (CD32)




Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene)
chr9_-_35111534 0.541 FAM214B
family with sequence similarity 214, member B
chr19_-_3047632 0.535 NM_001144761
TLE2
transducin-like enhancer of split 2 (E(sp1) homolog, Drosophila)
chr1_+_152635871 0.534 NM_178430
LCE2D
late cornified envelope 2D
chr13_+_60970590 0.532 NM_001146071
NM_030794
TDRD3

tudor domain containing 3

chr15_+_44580954 0.531 CASC4
cancer susceptibility candidate 4
chr5_+_140220811 0.529 NM_018911
NM_031856
PCDHA8

protocadherin alpha 8

chr11_+_117947726 0.524 NM_001083947
NM_001173551
NM_001173552
NM_019894
TMPRSS4



transmembrane protease, serine 4



chr19_-_42806928 0.519 NM_001145939
NM_001145940
PAFAH1B3

platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa)

chr22_+_41487787 0.516 EP300
E1A binding protein p300
chr17_+_75372164 0.516 NM_001113494
SEPT9
septin 9
chr5_+_42565562 0.512 NM_001242406
GHR
growth hormone receptor
chr1_+_152647770 0.510 NM_178429
LCE2C
late cornified envelope 2C
chrX_-_64139016 0.508 ZC4H2
zinc finger, C4H2 domain containing
chr17_-_71088814 0.497 SLC39A11
solute carrier family 39 (metal ion transporter), member 11
chr5_+_41925355 0.492 NM_012176
NM_033484
FBXO4

F-box protein 4

chr16_+_29674282 0.490 NM_001030288
SPN
sialophorin
chr15_+_44581045 0.490 CASC4
cancer susceptibility candidate 4
chr3_-_52567708 0.489 NM_001134231
NT5DC2
5'-nucleotidase domain containing 2
chr10_-_72083678 0.489 LRRC20
leucine rich repeat containing 20
chrX_+_13671224 0.488 NM_152634
TCEANC
transcription elongation factor A (SII) N-terminal and central domain containing
chr14_+_24837225 0.487 NM_001198965
NM_004554
NFATC4

nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4

chr10_+_69644708 0.486 SIRT1
sirtuin 1
chr15_+_77713229 0.486 NM_018200
HMG20A
high mobility group 20A
chr1_+_26856252 0.486 RPS6KA1
ribosomal protein S6 kinase, 90kDa, polypeptide 1
chrX_-_118827322 0.483 NM_015129
NM_145799
NM_145800
NM_145802
SEPT6



septin 6



chr7_+_150413597 0.482 NM_001199577
NM_130759
GIMAP1-GIMAP5
GIMAP1
GIMAP1-GIMAP5 readthrough
GTPase, IMAP family member 1
chr15_-_40630272 0.482 C15orf52
chromosome 15 open reading frame 52
chr15_-_71184611 0.481 NM_020147
THAP10
THAP domain containing 10
chr1_-_47655603 0.481 PDZK1IP1
PDZK1 interacting protein 1
chr17_-_45918561 0.478 SCRN2
secernin 2
chr19_-_6442004 0.477 SLC25A23
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
chr3_+_132379204 0.476 UBA5
ubiquitin-like modifier activating enzyme 5
chr5_+_42548144 0.475 NM_001242402
GHR
growth hormone receptor
chr6_-_119031230 0.468 NM_001178035
CEP85L
centrosomal protein 85kDa-like
chr2_+_220436953 0.467 NM_002191
INHA
inhibin, alpha
chr17_+_43224683 0.466 NM_006460
HEXIM1
hexamethylene bis-acetamide inducible 1
chr13_-_21099914 0.463 NM_015974
CRYL1
crystallin, lambda 1
chr1_-_47655723 0.462 NM_005764
PDZK1IP1
PDZK1 interacting protein 1
chr1_+_109102970 0.460 NM_001010883
FAM102B
family with sequence similarity 102, member B
chr6_+_151561094 0.454 NM_005100
AKAP12
A kinase (PRKA) anchor protein 12
chr2_-_136873740 0.453 NM_001008540
CXCR4
chemokine (C-X-C motif) receptor 4
chr3_+_32148000 0.451 NM_015141
GPD1L
glycerol-3-phosphate dehydrogenase 1-like
chr19_+_925984 0.450 NM_005224
ARID3A
AT rich interactive domain 3A (BRIGHT-like)
chr11_+_33563772 0.447 NM_012194
C11orf41
chromosome 11 open reading frame 41
chr19_+_50084586 0.445 NM_000951
PRRG2
proline rich Gla (G-carboxyglutamic acid) 2
chr8_+_9413439 0.445 NM_003747
TNKS
tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
chr17_+_72744802 0.443 SLC9A3R1
solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1
chr5_-_42993423 0.443 FLJ32255
uncharacterized LOC643977
chr11_+_827584 0.441 NM_173584
EFCAB4A
EF-hand calcium binding domain 4A
chr3_-_194991778 0.437 NM_152531
XXYLT1
xyloside xylosyltransferase 1
chr10_+_99258615 0.434 NM_024954
UBTD1
ubiquitin domain containing 1
chr8_-_103424897 0.431 NM_015902
UBR5
ubiquitin protein ligase E3 component n-recognin 5
chr8_-_42751622 0.425 NM_001160223
NM_001160224
NM_001160225
NM_030954
RNF170



ring finger protein 170



chr6_-_76203256 0.422 NM_015687
FILIP1
filamin A interacting protein 1
chr19_-_2042022 0.421 MKNK2
MAP kinase interacting serine/threonine kinase 2
chr17_+_72744746 0.416 NM_004252
SLC9A3R1
solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1
chr1_+_26856240 0.415 NM_002953
RPS6KA1
ribosomal protein S6 kinase, 90kDa, polypeptide 1
chr5_-_43040147 0.411 NM_001014279
C5orf39
chromosome 5 open reading frame 39
chr9_+_124048396 0.410 GSN
gelsolin
chr18_-_47013534 0.406 C18orf32
chromosome 18 open reading frame 32
chr22_+_38201232 0.403 H1F0
H1 histone family, member 0
chr9_+_130854127 0.401 NM_001006642
SLC25A25
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25
chr1_+_59775749 0.400 NM_001244714
FGGY
FGGY carbohydrate kinase domain containing
chr11_+_117947785 0.400 TMPRSS4
transmembrane protease, serine 4
chr4_+_90033967 0.399 NM_145715
TIGD2
tigger transposable element derived 2
chr17_-_76356153 0.398 NM_003955
SOCS3
suppressor of cytokine signaling 3
chr18_-_47013599 0.397 C18orf32
chromosome 18 open reading frame 32
chr10_+_64133915 0.396 NM_014951
NM_199450
NM_199451
ZNF365


zinc finger protein 365


chr15_+_44580870 0.394 NM_138423
NM_177974
CASC4

cancer susceptibility candidate 4

chrX_+_134124967 0.385 NM_001163438
CXorf69
chromosome X open reading frame 69

Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Nothing significant found in function category.