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• Mean activities

• Activities table
• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)
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Motif ID: NFE2.p2

Z-value: 0.996

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr4_-_76944585	14.236	NM_001565	CXCL10	chemokine (C-X-C motif) ligand 10
chr9_-_123688352	8.398		TRAF1	TNF receptor-associated factor 1
chr15_+_89182038	7.389	NM_002201	ISG20	interferon stimulated exonuclease gene 20kDa
chr11_-_102668892	5.829	NM_001145938 NM_002421	MMP1	matrix metallopeptidase 1 (interstitial collagenase)
chr4_+_74606222	5.769	NM_000584	IL8	interleukin 8
chr11_-_102668822	5.768		MMP1	matrix metallopeptidase 1 (interstitial collagenase)
chr10_-_6019880	5.617	NM_001243539	IL15RA	interleukin 15 receptor, alpha
chr2_+_152214105	5.281	NM_007115	TNFAIP6	tumor necrosis factor, alpha-induced protein 6
chr10_-_6019454	5.237	NM_002189 NM_172200	IL15RA	interleukin 15 receptor, alpha
chr1_+_183155393	5.229		LAMC2	laminin, gamma 2
chr19_+_4229494	4.742	NM_005755	EBI3	Epstein-Barr virus induced 3
chr12_+_78225068	4.683	NM_014903	NAV3	neuron navigator 3
chr1_+_183155173	4.200	NM_005562 NM_018891	LAMC2	laminin, gamma 2
chr6_-_31550065	4.037	NM_002341 NM_009588	LTB	lymphotoxin beta (TNF superfamily, member 3)
chr1_+_183155361	3.657		LAMC2	laminin, gamma 2
chr1_-_89488412	3.233	NM_018284	GBP3	guanylate binding protein 3
chr5_+_35856990	3.169	NM_002185	IL7R	interleukin 7 receptor
chrX_+_9431314	3.067	NM_001139466 NM_001139467 NM_001139468	TBL1X	transducin (beta)-like 1X-linked
chr12_+_56075329	3.028	NM_152637	METTL7B	methyltransferase like 7B
chr12_+_56075418	3.002		METTL7B	methyltransferase like 7B
chr16_+_57662301	2.552	NM_001145771 NM_001145772 NM_001145773 NM_201524 NM_201525	GPR56	G protein-coupled receptor 56
chr18_+_55888838	2.407		NEDD4L	neural precursor cell expressed, developmentally down-regulated 4-like
chr18_+_55888799	2.342		NEDD4L	neural precursor cell expressed, developmentally down-regulated 4-like
chr17_-_34207308	2.319	NM_002985	CCL5	chemokine (C-C motif) ligand 5
chr1_-_153521717	2.265	NM_002960	S100A3	S100 calcium binding protein A3
chr11_+_19372270	2.249	NM_001111018	NAV2	neuron navigator 2
chr21_-_36421586	2.219	NM_001754	RUNX1	runt-related transcription factor 1
chr9_+_103191795	2.212	NM_001198806	C9orf30	chromosome 9 open reading frame 30
chr16_+_56642477	2.173	NM_005953	MT2A	metallothionein 2A
chr20_+_6748744	2.032	NM_001200	BMP2	bone morphogenetic protein 2
chr18_+_55888750	2.019	NM_001144966	NEDD4L	neural precursor cell expressed, developmentally down-regulated 4-like
chr21_-_36421630	1.975		RUNX1	runt-related transcription factor 1
chr17_+_21191347	1.877	NM_002756	MAP2K3	mitogen-activated protein kinase kinase 3
chr6_-_138428477	1.822	NM_022121	PERP	PERP, TP53 apoptosis effector
chr18_+_61554938	1.807	NM_001143818 NM_002575	SERPINB2	serpin peptidase inhibitor, clade B (ovalbumin), member 2
chr7_+_28448970	1.755		LOC401317	uncharacterized LOC401317
chrX_-_154563735	1.753	NM_001289	CLIC2	chloride intracellular channel 2
chr1_+_36554452	1.721	NM_017825	ADPRHL2	ADP-ribosylhydrolase like 2
chr5_+_179247841	1.703	NM_003900	SQSTM1	sequestosome 1
chr11_-_65667809	1.680		FOSL1	FOS-like antigen 1
chr21_-_37852387	1.657	NM_001146079 NM_144492	CLDN14	claudin 14
chr17_+_79651035	1.623		HGS	hepatocyte growth factor-regulated tyrosine kinase substrate
chr1_-_6662681	1.620		KLHL21	kelch-like 21 (Drosophila)
chr11_+_35160385	1.617	NM_000610 NM_001001389 NM_001001390 NM_001001391 NM_001001392 NM_001202555 NM_001202556 NM_001202557	CD44	CD44 molecule (Indian blood group)
chr19_-_49658645	1.607	NM_002152	HRC	histidine rich calcium binding protein
chr4_+_77953942	1.576		SEPT11	septin 11
chr6_-_134496833	1.572		SGK1	serum/glucocorticoid regulated kinase 1
chr2_+_103035148	1.560	NM_003853	IL18RAP	interleukin 18 receptor accessory protein
chr19_+_13135368	1.544		NFIX	nuclear factor I/X (CCAAT-binding transcription factor)
chr11_-_65667860	1.543	NM_005438	FOSL1	FOS-like antigen 1
chr18_+_61637262	1.478	NM_001031848 NM_002640 NM_198833	SERPINB8	serpin peptidase inhibitor, clade B (ovalbumin), member 8
chr11_-_3862137	1.468		RHOG	ras homolog gene family, member G (rho G)
chr10_+_91092238	1.415	NM_001031683	IFIT3	interferon-induced protein with tetratricopeptide repeats 3
chr10_+_104155431	1.409	NM_002502	NFKB2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
chr11_-_65667858	1.409		FOSL1	FOS-like antigen 1
chr8_+_32504250	1.402	NM_013959	NRG1	neuregulin 1
chr17_+_79651042	1.394		HGS	hepatocyte growth factor-regulated tyrosine kinase substrate
chr3_+_11178778	1.393	NM_001098213	HRH1	histamine receptor H1
chr12_-_49259549	1.372	NM_014470	RND1	Rho family GTPase 1
chr15_+_67458492	1.366	NM_001145104	SMAD3	SMAD family member 3
chr7_-_1199822	1.315	NM_182491	ZFAND2A	zinc finger, AN1-type domain 2A
chr7_-_1199813	1.315		ZFAND2A	zinc finger, AN1-type domain 2A
chr17_+_32582295	1.300	NM_002982	CCL2	chemokine (C-C motif) ligand 2
chr17_+_79650961	1.287	NM_004712	HGS	hepatocyte growth factor-regulated tyrosine kinase substrate
chr6_-_84140854	1.269	NM_002395	ME1	malic enzyme 1, NADP(+)-dependent, cytosolic
chr16_+_57392694	1.253	NM_002990	CCL22	chemokine (C-C motif) ligand 22
chr21_-_35986744	1.248	NM_203417	RCAN1	regulator of calcineurin 1
chr12_-_51403028	1.235	NM_001174130	SLC11A2	solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2
chr3_-_39195101	1.227	NM_033027	CSRNP1	cysteine-serine-rich nuclear protein 1
chr7_-_1199785	1.214		ZFAND2A	zinc finger, AN1-type domain 2A
chr22_-_27014037	1.213		CRYBB1	crystallin, beta B1
chr1_+_150122415	1.198		PLEKHO1	pleckstrin homology domain containing, family O member 1
chr21_+_26934440	1.159		MIR155HG	MIR155 host gene (non-protein coding)
chr5_+_179247903	1.159		SQSTM1	sequestosome 1
chr6_-_84140758	1.158		ME1	malic enzyme 1, NADP(+)-dependent, cytosolic
chr1_+_150122246	1.153		PLEKHO1	pleckstrin homology domain containing, family O member 1
chr22_-_27013959	1.143	NM_001887	CRYBB1	crystallin, beta B1
chr6_-_46293628	1.139	NM_005822	RCAN2	regulator of calcineurin 2
chr6_-_84140744	1.136		ME1	malic enzyme 1, NADP(+)-dependent, cytosolic
chr9_+_35673852	1.126	NM_001216	CA9	carbonic anhydrase IX
chr1_+_150122095	1.125	NM_016274	PLEKHO1	pleckstrin homology domain containing, family O member 1
chr11_-_3862183	1.120	NM_001665	RHOG	ras homolog gene family, member G (rho G)
chr6_-_46293404	1.120		RCAN2	regulator of calcineurin 2
chr22_-_45608232	1.118		KIAA0930	KIAA0930
chr3_-_39195034	1.104		CSRNP1	cysteine-serine-rich nuclear protein 1
chr4_-_139163222	1.096	NM_014331	SLC7A11	solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
chr6_-_84140651	1.094		ME1	malic enzyme 1, NADP(+)-dependent, cytosolic
chr6_-_35888889	1.069		SRPK1	SRSF protein kinase 1
chr4_-_122085475	1.062	NM_024873	TNIP3	TNFAIP3 interacting protein 3
chr1_+_152881022	1.053	NM_005547	IVL	involucrin
chr6_-_35888937	1.042	NM_003137	SRPK1	SRSF protein kinase 1
chr12_-_56236614	1.019	NM_002429	MMP19	matrix metallopeptidase 19
chr6_-_35888816	1.017		SRPK1	SRSF protein kinase 1
chr11_+_62649160	1.013		SLC3A2	solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2
chr16_-_1429612	1.012	NM_001193389 NM_023076	UNKL	unkempt homolog (Drosophila)-like
chr3_+_50284325	1.007	NM_001166425	GNAI2	guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
chr7_-_98467483	1.007		TMEM130	transmembrane protein 130
chr7_+_143058794	1.006		ZYX	zyxin
chr7_-_98467663	1.005	NM_001134450 NM_001134451 NM_152913	TMEM130	transmembrane protein 130
chr11_+_35160666	1.001		CD44	CD44 molecule (Indian blood group)
chr9_+_33026482	0.997		DNAJA1	DnaJ (Hsp40) homolog, subfamily A, member 1
chr5_-_158636489	0.996	NM_001199383	RNF145	ring finger protein 145
chr15_+_67418053	0.995	NM_001145102	SMAD3	SMAD family member 3
chr1_-_183559463	0.990		NCF2	neutrophil cytosolic factor 2
chr6_-_134497069	0.990	NM_001143678	SGK1	serum/glucocorticoid regulated kinase 1
chr5_+_179247911	0.979		SQSTM1	sequestosome 1
chr17_+_79651072	0.978		HGS	hepatocyte growth factor-regulated tyrosine kinase substrate
chr1_-_6662898	0.975	NM_014851	KLHL21	kelch-like 21 (Drosophila)
chr14_+_58711599	0.950		PSMA3	proteasome (prosome, macropain) subunit, alpha type, 3
chr3_+_105085553	0.946	NM_001243280 NM_001243281 NM_001243283 NM_001627	ALCAM	activated leukocyte cell adhesion molecule
chr7_-_98467615	0.928		TMEM130	transmembrane protein 130
chr17_-_39280377	0.926	NM_031854	KRTAP4-12	keratin associated protein 4-12
chr17_-_79881304	0.915	NM_032711	MAFG	v-maf musculoaponeurotic fibrosarcoma oncogene homolog G (avian)
chr16_-_28607694	0.903	NM_177528	SULT1A2	sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
chr6_+_106546736	0.897	NM_182907	PRDM1	PR domain containing 1, with ZNF domain
chr15_+_71184781	0.891	NM_001199017 NM_017691 NM_001199018	LRRC49	leucine rich repeat containing 49
chr16_-_28620648	0.886	NM_177530 NM_177534	SULT1A1	sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
chr17_+_30771520	0.884		PSMD11	proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
chr2_+_69201704	0.871	NM_019617	GKN1	gastrokine 1
chr11_-_9025531	0.846	NM_020645	NRIP3	nuclear receptor interacting protein 3
chr19_+_12949258	0.846	NM_014975	MAST1	microtubule associated serine/threonine kinase 1
chr14_-_91710851	0.841	NM_001177676	GPR68	G protein-coupled receptor 68
chr2_-_204399906	0.827	NM_203365 NM_213589	RAPH1	Ras association (RalGDS/AF-6) and pleckstrin homology domains 1
chr19_-_35981345	0.827	NM_001244847 NM_207392	KRTDAP	keratinocyte differentiation-associated protein
chrX_-_110513750	0.826	NM_014289	CAPN6	calpain 6
chr11_-_65430214	0.816		RELA	v-rel reticuloendotheliosis viral oncogene homolog A (avian)
chr3_-_14220071	0.806	NM_001145769 NM_004628	XPC	xeroderma pigmentosum, complementation group C
chr7_-_92462637	0.794		CDK6	cyclin-dependent kinase 6
chr6_+_34206567	0.793	NM_145905	HMGA1	high mobility group AT-hook 1
chr19_-_46285645	0.791		DMPK	dystrophia myotonica-protein kinase
chr16_+_89988416	0.779	NM_001197181	TUBB3	tubulin, beta 3 class III
chr6_-_33548017	0.777	NM_001188	BAK1	BCL2-antagonist/killer 1
chr3_+_105085740	0.770		ALCAM	activated leukocyte cell adhesion molecule
chr6_-_159239269	0.770	NM_003379	EZR	ezrin
chr11_+_67007488	0.769		KDM2A	lysine (K)-specific demethylase 2A
chr16_+_83986826	0.767	NM_182981	OSGIN1	oxidative stress induced growth inhibitor 1
chr7_+_143078444	0.757		ZYX	zyxin
chr5_-_169724614	0.756		LCP2	lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr9_-_134585107	0.755	NM_198679	RAPGEF1	Rap guanine nucleotide exchange factor (GEF) 1
chr1_+_40627031	0.755	NM_012421	RLF	rearranged L-myc fusion
chr11_+_35160815	0.752		CD44	CD44 molecule (Indian blood group)
chr7_+_143078447	0.746		ZYX	zyxin
chr12_+_69202796	0.744		MDM2	Mdm2 p53 binding protein homolog (mouse)
chr11_-_65430427	0.741	NM_001145138 NM_001243984 NM_001243985 NM_021975	RELA	v-rel reticuloendotheliosis viral oncogene homolog A (avian)
chr12_-_58165877	0.741	NM_005371 NM_023033	METTL1	methyltransferase like 1
chr5_-_175843360	0.732		CLTB	clathrin, light chain B
chr3_+_48507209	0.731	NM_016381 NM_033629	TREX1	three prime repair exonuclease 1
chr1_+_40627055	0.729		RLF	rearranged L-myc fusion
chr5_-_175843531	0.727	NM_001834 NM_007097	CLTB	clathrin, light chain B
chr21_-_36260086	0.725		RUNX1	runt-related transcription factor 1
chr10_-_95170	0.719	NM_177987	TUBB8	tubulin, beta 8 class VIII
chr20_-_1309809	0.706	NM_080489	SDCBP2	syndecan binding protein (syntenin) 2
chr15_+_98503907	0.704	NM_183376	ARRDC4	arrestin domain containing 4
chr14_-_24777064	0.690
chr9_-_140083034	0.689	NM_013366	ANAPC2	anaphase promoting complex subunit 2
chr6_-_159239198	0.688		EZR	ezrin
chr7_+_143078457	0.686		ZYX	zyxin
chr3_+_48507621	0.686		TREX1	three prime repair exonuclease 1
chr16_+_87425874	0.686		MAP1LC3B	microtubule-associated protein 1 light chain 3 beta
chr1_+_36621751	0.674	NM_018067	MAP7D1	MAP7 domain containing 1
chr1_+_205198058	0.673	NM_001242925	TMCC2	transmembrane and coiled-coil domain family 2
chr7_+_28725597	0.663	NM_001011666	CREB5	cAMP responsive element binding protein 5
chr12_+_64845839	0.656	NM_013254	TBK1	TANK-binding kinase 1
chr3_-_150920946	0.655	NM_013308	GPR171	G protein-coupled receptor 171
chr18_+_21572736	0.654	NM_153211	TTC39C	tetratricopeptide repeat domain 39C
chr6_-_159239254	0.650		EZR	ezrin
chr1_+_156084565	0.648		LMNA	lamin A/C
chr6_-_33547833	0.647		BAK1	BCL2-antagonist/killer 1
chr2_-_7005764	0.646	NM_207315	CMPK2	cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial
chr16_+_87425946	0.646		MAP1LC3B	microtubule-associated protein 1 light chain 3 beta
chr1_+_156084458	0.644	NM_005572 NM_170707 NM_170708	LMNA	lamin A/C
chr19_-_47735858	0.641	NM_001127240 NM_001127241 NM_001127242	BBC3	BCL2 binding component 3
chr17_+_74381186	0.619	NM_001142602	SPHK1	sphingosine kinase 1
chr22_-_19512001	0.618		CLDN5	claudin 5
chr3_+_183903970	0.617		ABCF3	ATP-binding cassette, sub-family F (GCN20), member 3
chr21_-_36421578	0.616		RUNX1	runt-related transcription factor 1
chr22_+_21369441	0.616	NM_001159554 NM_005446	P2RX6	purinergic receptor P2X, ligand-gated ion channel, 6
chr5_-_35048239	0.612	NM_031900	AGXT2	alanine--glyoxylate aminotransferase 2
chr3_+_30647901	0.610	NM_001024847 NM_003242	TGFBR2	transforming growth factor, beta receptor II (70/80kDa)
chr6_+_64231626	0.610		PTP4A1	protein tyrosine phosphatase type IVA, member 1
chr19_-_46285746	0.609		DMPK	dystrophia myotonica-protein kinase
chr8_-_145025043	0.607	NM_201380	PLEC	plectin
chr5_+_72143929	0.602	NM_153188	TNPO1	transportin 1
chr19_+_50031232	0.599		RCN3	reticulocalbin 3, EF-hand calcium binding domain
chr20_+_44746889	0.597	NM_001250 NM_152854	CD40	CD40 molecule, TNF receptor superfamily member 5
chr20_+_48807365	0.588		CEBPB	CCAAT/enhancer binding protein (C/EBP), beta
chr7_+_143078399	0.586		ZYX	zyxin
chr19_+_38794800	0.585	NM_033520	C19orf33	chromosome 19 open reading frame 33
chr2_-_180610768	0.585	NM_001113397	ZNF385B	zinc finger protein 385B
chr18_+_21594349	0.584	NM_001135993 NM_001243425	TTC39C	tetratricopeptide repeat domain 39C
chr3_+_183903862	0.584	NM_018358	ABCF3	ATP-binding cassette, sub-family F (GCN20), member 3
chr11_+_128563955	0.583		FLI1	Friend leukemia virus integration 1
chr17_-_56595192	0.582	NM_004687	MTMR4	myotubularin related protein 4
chr1_-_95007139	0.581	NM_001178096 NM_001993	F3	coagulation factor III (thromboplastin, tissue factor)
chr9_-_19786886	0.580	NM_001193288 NM_020344	SLC24A2	solute carrier family 24 (sodium/potassium/calcium exchanger), member 2
chr11_+_64323089	0.576	NM_018484	SLC22A11	solute carrier family 22 (organic anion/urate transporter), member 11
chr7_+_100728719	0.576	NM_030961	TRIM56	tripartite motif containing 56
chr11_+_35160832	0.575		CD44	CD44 molecule (Indian blood group)
chr16_+_87425998	0.572		MAP1LC3B	microtubule-associated protein 1 light chain 3 beta
chr17_+_74380943	0.571		SPHK1	sphingosine kinase 1

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.81	7.36e-06	GO:0009893	positive regulation of metabolic process
1.83	1.24e-05	GO:0010604	positive regulation of macromolecule metabolic process
1.28	2.08e-05	GO:0050896	response to stimulus
1.77	8.14e-05	GO:0050790	regulation of catalytic activity
1.76	1.02e-04	GO:0031325	positive regulation of cellular metabolic process
1.23	1.05e-04	GO:0050789	regulation of biological process
1.21	1.18e-04	GO:0065007	biological regulation
1.35	1.53e-04	GO:0051716	cellular response to stimulus
1.66	1.75e-04	GO:0065009	regulation of molecular function
1.40	1.85e-04	GO:0007165	signal transduction
1.23	2.50e-04	GO:0050794	regulation of cellular process
1.37	2.79e-04	GO:0023052	signaling
1.50	2.88e-04	GO:0042221	response to chemical stimulus
1.45	3.23e-04	GO:0048518	positive regulation of biological process
1.91	3.23e-04	GO:0044093	positive regulation of molecular function
1.71	3.56e-04	GO:0002376	immune system process
1.47	4.89e-04	GO:0048522	positive regulation of cellular process
1.97	4.94e-04	GO:0043085	positive regulation of catalytic activity
5.24	5.64e-04	GO:0006521	regulation of cellular amino acid metabolic process
4.88	5.87e-04	GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
4.88	5.87e-04	GO:0072395	signal transduction involved in cell cycle checkpoint
4.88	5.87e-04	GO:0072401	signal transduction involved in DNA integrity checkpoint
4.88	5.87e-04	GO:0072404	signal transduction involved in G1/S transition checkpoint
4.88	5.87e-04	GO:0072413	signal transduction involved in mitotic cell cycle checkpoint
4.88	5.87e-04	GO:0072422	signal transduction involved in DNA damage checkpoint
4.88	5.87e-04	GO:0072431	signal transduction involved in mitotic cell cycle G1/S transition DNA damage checkpoint
4.88	5.87e-04	GO:0072474	signal transduction involved in mitotic cell cycle G1/S checkpoint
1.46	9.20e-04	GO:0006950	response to stress
1.67	1.03e-03	GO:0010033	response to organic substance
1.46	1.14e-03	GO:0048519	negative regulation of biological process
4.65	1.15e-03	GO:0033238	regulation of cellular amine metabolic process
4.65	1.15e-03	GO:0071158	positive regulation of cell cycle arrest
1.90	1.34e-03	GO:0006955	immune response
1.48	1.76e-03	GO:0048523	negative regulation of cellular process
2.21	2.31e-03	GO:0043086	negative regulation of catalytic activity
4.38	2.65e-03	GO:0031571	mitotic cell cycle G1/S transition DNA damage checkpoint
3.92	2.69e-03	GO:0030330	DNA damage response, signal transduction by p53 class mediator
1.69	4.69e-03	GO:0051246	regulation of protein metabolic process
4.19	4.74e-03	GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
2.87	4.76e-03	GO:0052548	regulation of endopeptidase activity
1.89	5.92e-03	GO:0010628	positive regulation of gene expression
1.12	6.19e-03	GO:0009987	cellular process
3.87	6.63e-03	GO:0051351	positive regulation of ligase activity
1.83	7.56e-03	GO:0010557	positive regulation of macromolecule biosynthetic process
2.02	8.86e-03	GO:0009607	response to biotic stimulus
2.76	9.87e-03	GO:0052547	regulation of peptidase activity
2.00	1.00e-02	GO:0044092	negative regulation of molecular function
1.76	1.09e-02	GO:0009891	positive regulation of biosynthetic process
3.40	1.13e-02	GO:0090068	positive regulation of cell cycle process
4.15	1.19e-02	GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
1.45	1.27e-02	GO:0030154	cell differentiation
3.87	1.38e-02	GO:0051439	regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
10.83	1.41e-02	GO:0060600	dichotomous subdivision of an epithelial terminal unit
3.82	1.63e-02	GO:0031575	mitotic cell cycle G1/S transition checkpoint
3.82	1.63e-02	GO:0051443	positive regulation of ubiquitin-protein ligase activity
3.82	1.63e-02	GO:0071779	G1/S transition checkpoint
2.03	1.74e-02	GO:0045944	positive regulation of transcription from RNA polymerase II promoter
1.30	2.00e-02	GO:0032502	developmental process
1.79	2.00e-02	GO:2000026	regulation of multicellular organismal development
3.97	2.03e-02	GO:0051352	negative regulation of ligase activity
3.97	2.03e-02	GO:0051444	negative regulation of ubiquitin-protein ligase activity
1.44	2.04e-02	GO:0048869	cellular developmental process
1.87	2.13e-02	GO:0045893	positive regulation of transcription, DNA-dependent
3.72	2.25e-02	GO:0031145	anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process
1.73	2.30e-02	GO:0031328	positive regulation of cellular biosynthetic process
2.84	2.32e-02	GO:0010498	proteasomal protein catabolic process
2.84	2.32e-02	GO:0043161	proteasomal ubiquitin-dependent protein catabolic process
1.67	2.61e-02	GO:0042127	regulation of cell proliferation
3.63	3.07e-02	GO:2000045	regulation of G1/S transition of mitotic cell cycle
1.74	3.28e-02	GO:0031399	regulation of protein modification process
1.75	3.43e-02	GO:0051173	positive regulation of nitrogen compound metabolic process
12.40	3.72e-02	GO:0060678	dichotomous subdivision of terminal units involved in ureteric bud branching
1.68	3.82e-02	GO:0009611	response to wounding
3.38	4.13e-02	GO:0051340	regulation of ligase activity
2.39	4.46e-02	GO:0030036	actin cytoskeleton organization

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
5.67	3.87e-07	GO:0000502	proteasome complex
1.46	3.22e-04	GO:0044459	plasma membrane part
1.78	5.33e-04	GO:0005626	insoluble fraction
1.61	3.64e-03	GO:0000267	cell fraction
9.92	3.84e-03	GO:0022624	proteasome accessory complex
1.71	4.79e-03	GO:0005624	membrane fraction
11.03	1.14e-02	GO:0005838	proteasome regulatory particle
1.79	1.57e-02	GO:0030054	cell junction

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.24	3.72e-06	GO:0005515	protein binding
2.76	2.24e-03	GO:0005126	cytokine receptor binding
1.64	4.89e-03	GO:0005102	receptor binding
1.71	1.68e-02	GO:0019899	enzyme binding
2.61	4.34e-02	GO:0061135	endopeptidase regulator activity
13.23	4.70e-02	GO:0061133	endopeptidase activator activity