Motif ID: NFE2L1.p2

Z-value: 1.196


Transcription factors associated with NFE2L1.p2:

Gene SymbolEntrez IDGene Name
NFE2L1 4779 nuclear factor (erythroid-derived 2)-like 1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.p-valuePlot
NFE2L1chr17_+_461257250.262.1e-01Click!


Activity profile for motif NFE2L1.p2.

activity profile for motif NFE2L1.p2


Sorted Z-values histogram for motif NFE2L1.p2

Sorted Z-values for motif NFE2L1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NFE2L1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr4_+_74606222 4.041 NM_000584
 IL8
interleukin 8
chr1_+_212738675 2.315 NM_001030287
 ATF3
activating transcription factor 3
chr5_-_94417544 1.688 NM_001002796
 MCTP1
multiple C2 domains, transmembrane 1
chr13_+_97874704 1.672 MBNL2
muscleblind-like 2 (Drosophila)
chr7_+_65419441 1.662 VKORC1L1
vitamin K epoxide reductase complex, subunit 1-like 1
chr15_+_67418053 1.558 NM_001145102
 SMAD3
SMAD family member 3
chr21_+_47545896 1.552 COL6A2
collagen, type VI, alpha 2
chr1_-_173020011 1.510 NM_005092
 TNFSF18
tumor necrosis factor (ligand) superfamily, member 18
chr4_-_139163222 1.501 NM_014331
 SLC7A11
solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
chr9_-_123688352 1.423 TRAF1
TNF receptor-associated factor 1
chr10_+_35464514 1.362 NM_182769
NM_182770
 CREM

cAMP responsive element modulator

chr1_-_169703178 1.353 NM_000450
 SELE
selectin E
chr2_+_108994366 1.334 NM_006588
 SULT1C4
sulfotransferase family, cytosolic, 1C, member 4
chr2_-_28113954 1.305 LOC100302650
uncharacterized LOC100302650
chr2_-_136873740 1.287 NM_001008540
 CXCR4
chemokine (C-X-C motif) receptor 4
chr6_-_10419786 1.248 NM_001042425
 TFAP2A
transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chrX_+_78426468 1.246 NM_032553
 GPR174
G protein-coupled receptor 174
chr11_+_6897855 1.214 NM_207186
 OR10A4
olfactory receptor, family 10, subfamily A, member 4
chr2_+_46524901 1.211 EPAS1
endothelial PAS domain protein 1
chr2_-_165551178 1.161 COBLL1
COBL-like 1

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 26 entries
enrichment   p-value GO term description
1.65 1.22e-02 GO:0016337 cell-cell adhesion
1.61 5.13e-06 GO:0042060 wound healing
1.59 2.30e-04 GO:0007596 blood coagulation
1.59 2.30e-04 GO:0050817 coagulation
1.58 3.40e-04 GO:0007599 hemostasis
1.51 9.13e-03 GO:0001775 cell activation
1.49 3.10e-06 GO:0009611 response to wounding
1.48 6.26e-03 GO:0050878 regulation of body fluid levels
1.29 1.05e-05 GO:0065008 regulation of biological quality
1.22 1.21e-03 GO:0048518 positive regulation of biological process
1.22 2.19e-03 GO:0006950 response to stress
1.22 2.30e-03 GO:0048522 positive regulation of cellular process
1.22 3.16e-03 GO:0048519 negative regulation of biological process
1.20 2.80e-05 GO:0023052 signaling
1.20 1.04e-04 GO:0007165 signal transduction
1.20 5.24e-03 GO:0048731 system development
1.19 1.34e-03 GO:0048856 anatomical structure development
1.18 4.21e-03 GO:0007275 multicellular organismal development
1.17 3.61e-06 GO:0032501 multicellular organismal process
1.17 4.61e-04 GO:0051716 cellular response to stimulus

Gene overrepresentation in compartment category:

Showing 1 to 12 of 12 entries
enrichment   p-value GO term description
1.57 1.67e-02 GO:0015629 actin cytoskeleton
1.46 4.30e-02 GO:0043005 neuron projection
1.42 3.04e-04 GO:0031410 cytoplasmic vesicle
1.41 4.20e-04 GO:0031982 vesicle
1.41 1.03e-03 GO:0016023 cytoplasmic membrane-bounded vesicle
1.40 1.32e-03 GO:0031988 membrane-bounded vesicle
1.38 6.53e-04 GO:0042995 cell projection
1.23 2.62e-04 GO:0044459 plasma membrane part
1.16 8.36e-05 GO:0071944 cell periphery
1.16 1.16e-04 GO:0005886 plasma membrane
1.08 1.47e-03 GO:0005737 cytoplasm
1.08 1.25e-02 GO:0016020 membrane

Gene overrepresentation in function category:

Showing 1 to 5 of 5 entries
enrichment   p-value GO term description
1.55 4.98e-02 GO:0016879 ligase activity, forming carbon-nitrogen bonds
1.53 4.77e-02 GO:0003779 actin binding
1.41 3.03e-02 GO:0008092 cytoskeletal protein binding
1.34 4.31e-02 GO:0015075 ion transmembrane transporter activity
1.13 4.97e-07 GO:0005515 protein binding