Motif ID: NFY{A,B,C}.p2

Z-value: 2.598


Transcription factors associated with NFY{A,B,C}.p2:

Gene SymbolEntrez IDGene Name
NFYA 4800 nuclear transcription factor Y, alpha
NFYB 4801 nuclear transcription factor Y, beta
NFYC 4802 nuclear transcription factor Y, gamma

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.p-valuePlot
NFYCchr1_+_412045090.717.1e-05Click!
NFYBchr12_-_1045318750.442.6e-02Click!
NFYAchr6_+_41040891-0.377.2e-02Click!


Activity profile for motif NFY{A,B,C}.p2.

activity profile for motif NFY{A,B,C}.p2


Sorted Z-values histogram for motif NFY{A,B,C}.p2

Sorted Z-values for motif NFY{A,B,C}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NFY{A,B,C}.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr3_+_8543508 10.761 NM_014583
LMCD1
LIM and cysteine-rich domains 1
chr3_+_8543539 8.149 LMCD1
LIM and cysteine-rich domains 1
chr1_+_221052735 7.239 NM_021958
HLX
H2.0-like homeobox
chr1_+_221052845 7.227 HLX
H2.0-like homeobox
chr14_-_91526912 7.185 NM_004755
NM_182398
RPS6KA5

ribosomal protein S6 kinase, 90kDa, polypeptide 5

chr1_+_221053000 6.685 HLX
H2.0-like homeobox
chr17_-_47841468 6.250 FAM117A
family with sequence similarity 117, member A
chr3_+_193853937 6.123 HES1
hairy and enhancer of split 1, (Drosophila)
chr3_+_193853930 5.684 NM_005524
HES1
hairy and enhancer of split 1, (Drosophila)
chr2_-_240322620 5.217 NM_006037
HDAC4
histone deacetylase 4
chr6_+_160183510 4.922 ACAT2
acetyl-CoA acetyltransferase 2
chr10_+_112631675 4.465 PDCD4
programmed cell death 4 (neoplastic transformation inhibitor)
chr15_-_23378217 4.448 HERC2P2
hect domain and RLD 2 pseudogene 2
chr6_+_160183062 4.342 ACAT2
acetyl-CoA acetyltransferase 2
chr8_+_11660272 4.300 FDFT1
farnesyl-diphosphate farnesyltransferase 1
chr6_+_160182988 4.292 NM_005891
ACAT2
acetyl-CoA acetyltransferase 2
chr8_+_11660179 4.204 NM_004462
FDFT1
farnesyl-diphosphate farnesyltransferase 1
chr8_+_11660207 4.156 FDFT1
farnesyl-diphosphate farnesyltransferase 1
chr10_+_112631552 4.134 NM_001199492
NM_014456
NM_145341
PDCD4


programmed cell death 4 (neoplastic transformation inhibitor)


chr12_+_79258588 4.074 SYT1
synaptotagmin I
chr12_+_79258517 4.063 SYT1
synaptotagmin I
chr17_-_47841517 4.029 NM_030802
FAM117A
family with sequence similarity 117, member A
chr19_+_58790306 3.989 NM_021089
ZNF8
zinc finger protein 8
chr2_+_191745791 3.981 GLS
glutaminase
chr20_-_45985411 3.920 NM_012408
NM_183047
NM_183048
ZMYND8


zinc finger, MYND-type containing 8


chr2_+_203499819 3.871 NM_173511
FAM117B
family with sequence similarity 117, member B
chr8_+_11660520 3.765 FDFT1
farnesyl-diphosphate farnesyltransferase 1
chr8_+_6565870 3.761 NM_018361
AGPAT5
1-acylglycerol-3-phosphate O-acyltransferase 5 (lysophosphatidic acid acyltransferase, epsilon)
chr14_-_78083109 3.737 NM_004863
SPTLC2
serine palmitoyltransferase, long chain base subunit 2
chr11_-_19262424 3.737 NM_024680
E2F8
E2F transcription factor 8
chr14_-_100772774 3.716 NM_001039355
SLC25A29
solute carrier family 25, member 29
chr5_+_74632992 3.689 NM_000859
NM_001130996
HMGCR

3-hydroxy-3-methylglutaryl-CoA reductase

chr14_-_53019036 3.684 NM_001160047
NM_020784
TXNDC16

thioredoxin domain containing 16

chr7_+_100136845 3.683 AGFG2
ArfGAP with FG repeats 2
chr20_-_62680880 3.623 NM_018419
SOX18
SRY (sex determining region Y)-box 18
chr17_+_68165660 3.495 NM_000891
KCNJ2
potassium inwardly-rectifying channel, subfamily J, member 2
chr5_+_74633043 3.419 HMGCR
3-hydroxy-3-methylglutaryl-CoA reductase
chr1_+_212458867 3.396 NM_006243
PPP2R5A
protein phosphatase 2, regulatory subunit B', alpha
chr17_+_72744775 3.384 SLC9A3R1
solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1
chr19_-_14640048 3.372 DNAJB1
DnaJ (Hsp40) homolog, subfamily B, member 1
chr2_-_73460326 3.331 NM_032319
PRADC1
protease-associated domain containing 1
chr1_+_1981902 3.321 NM_002744
PRKCZ
protein kinase C, zeta
chr14_-_74551159 3.292 NM_005589
ALDH6A1
aldehyde dehydrogenase 6 family, member A1
chr14_-_74551073 3.277 ALDH6A1
aldehyde dehydrogenase 6 family, member A1
chr17_+_39382878 3.172 NM_031961
KRTAP9-2
keratin associated protein 9-2
chr2_-_191878882 3.159 STAT1
signal transducer and activator of transcription 1, 91kDa
chrX_-_62975005 3.143 NM_001173480
NM_015185
ARHGEF9

Cdc42 guanine nucleotide exchange factor (GEF) 9

chr7_+_94024201 3.139 COL1A2
collagen, type I, alpha 2
chrX_-_62974987 3.110 ARHGEF9
Cdc42 guanine nucleotide exchange factor (GEF) 9
chr14_-_76127526 3.096 NM_007176
C14orf1
chromosome 14 open reading frame 1
chr8_+_11660297 3.063 FDFT1
farnesyl-diphosphate farnesyltransferase 1
chr7_+_152161119 3.016 LOC100128822
uncharacterized LOC100128822
chrX_-_62974942 2.960 ARHGEF9
Cdc42 guanine nucleotide exchange factor (GEF) 9
chr17_+_48172508 2.958 NM_001199900
NM_002611
NM_001199899
PDK2


pyruvate dehydrogenase kinase, isozyme 2


chr9_+_79093256 2.949 NM_001097635
GCNT1
glucosaminyl (N-acetyl) transferase 1, core 2
chr14_+_53019865 2.880 NM_001099652
GPR137C
G protein-coupled receptor 137C
chr2_-_191878908 2.874 STAT1
signal transducer and activator of transcription 1, 91kDa
chr12_-_124068864 2.835


chr19_+_4910339 2.794 NM_013282
UHRF1
ubiquitin-like with PHD and ring finger domains 1
chr19_-_2042022 2.778 MKNK2
MAP kinase interacting serine/threonine kinase 2
chr2_-_191878883 2.768 STAT1
signal transducer and activator of transcription 1, 91kDa
chr11_-_67888857 2.766 NM_001277
NM_212469
CHKA

choline kinase alpha

chr12_-_56727720 2.764 NM_001166279
NM_014871
PAN2

PAN2 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)

chr4_-_186877869 2.739 NM_021069
SORBS2
sorbin and SH3 domain containing 2
chr11_-_67888670 2.734 CHKA
choline kinase alpha
chr4_+_108852671 2.689 NM_183075
CYP2U1
cytochrome P450, family 2, subfamily U, polypeptide 1
chr12_+_79258448 2.649 NM_005639
SYT1
synaptotagmin I
chr4_+_100871625 2.630 LOC256880
uncharacterized LOC256880
chr8_-_77912296 2.612 NM_000318
NM_001079867
PEX2

peroxisomal biogenesis factor 2

chr14_+_65878579 2.599 FUT8
fucosyltransferase 8 (alpha (1,6) fucosyltransferase)
chr2_+_61292999 2.587 NM_001129993
KIAA1841
KIAA1841
chr7_+_94023872 2.578 NM_000089
COL1A2
collagen, type I, alpha 2
chr5_+_148737569 2.557 NM_024028
PCYOX1L
prenylcysteine oxidase 1 like
chr2_-_191878924 2.543 NM_007315
NM_139266
STAT1

signal transducer and activator of transcription 1, 91kDa

chr2_+_61293038 2.530 KIAA1841
KIAA1841
chr17_-_57232799 2.520 NM_001100595
NM_182620
SKA2

spindle and kinetochore associated complex subunit 2

chr5_+_148737613 2.503 PCYOX1L
prenylcysteine oxidase 1 like
chr12_-_107380837 2.503 NM_001033050
NM_025198
MTERFD3

MTERF domain containing 3

chr1_+_227127937 2.498 NM_020247
ADCK3
aarF domain containing kinase 3
chr1_+_61542928 2.490 NM_001145511
NFIA
nuclear factor I/A
chr1_+_164528586 2.485 NM_001204961
NM_001204963
NM_002585
PBX1


pre-B-cell leukemia homeobox 1


chr21_+_47744032 2.470 NM_006031
PCNT
pericentrin
chr2_+_191745568 2.461 GLS
glutaminase
chr14_+_54863672 2.452 NM_001130851
NM_005192
CDKN3

cyclin-dependent kinase inhibitor 3

chr1_+_155278538 2.445 NM_001135822
NM_001242824
NM_001242825
NM_002004
FDPS



farnesyl diphosphate synthase



chr4_+_166248816 2.436 NM_001017369
NM_006745
MSMO1

methylsterol monooxygenase 1

chr1_+_227127959 2.406 ADCK3
aarF domain containing kinase 3
chr1_+_227127999 2.400 ADCK3
aarF domain containing kinase 3
chr12_-_56727446 2.379 NM_001127460
PAN2
PAN2 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)
chr3_-_148804122 2.376 NM_003071
NM_139048
HLTF

helicase-like transcription factor

chr1_+_155278727 2.376 FDPS
farnesyl diphosphate synthase
chr17_+_72744794 2.344 SLC9A3R1
solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1
chr13_-_101327027 2.329 TMTC4
transmembrane and tetratricopeptide repeat containing 4
chr1_-_225615787 2.329 NM_002296
LBR
lamin B receptor
chr19_-_14629227 2.323 DNAJB1
DnaJ (Hsp40) homolog, subfamily B, member 1
chr2_-_240322692 2.316 HDAC4
histone deacetylase 4
chr17_+_72744746 2.310 NM_004252
SLC9A3R1
solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1
chrX_+_151999565 2.307 NSDHL
NAD(P) dependent steroid dehydrogenase-like
chr1_+_155278677 2.304 NM_001135821
FDPS
farnesyl diphosphate synthase
chr13_-_45010974 2.301 TSC22D1
TSC22 domain family, member 1
chr13_-_45010994 2.292 TSC22D1
TSC22 domain family, member 1
chr19_-_2041862 2.284 MKNK2
MAP kinase interacting serine/threonine kinase 2
chr13_-_45010937 2.277 TSC22D1
TSC22 domain family, member 1
chr13_-_101327102 2.269 NM_001079669
NM_032813
TMTC4

transmembrane and tetratricopeptide repeat containing 4

chr20_+_30193083 2.262 NM_002165
NM_181353
ID1

inhibitor of DNA binding 1, dominant negative helix-loop-helix protein

chr4_-_149363498 2.240 NM_000901
NM_001166104
NR3C2

nuclear receptor subfamily 3, group C, member 2

chr1_-_55352920 2.222 NM_014762
DHCR24
24-dehydrocholesterol reductase
chr1_-_55352893 2.217 DHCR24
24-dehydrocholesterol reductase
chr17_+_61562177 2.214 NM_001178057
NM_152830
ACE

angiotensin I converting enzyme (peptidyl-dipeptidase A) 1

chrX_+_151999510 2.212 NM_001129765
NM_015922
NSDHL

NAD(P) dependent steroid dehydrogenase-like

chr17_+_58755158 2.198 NM_001099432
NM_017679
BCAS3

breast carcinoma amplified sequence 3

chr14_-_76127158 2.190 C14orf1
chromosome 14 open reading frame 1
chr17_+_72744802 2.183 SLC9A3R1
solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1
chr17_-_57232524 2.182 SKA2
spindle and kinetochore associated complex subunit 2
chr19_-_14629235 2.179


chr3_+_39851028 2.164 NM_015460
MYRIP
myosin VIIA and Rab interacting protein
chr10_-_1094854 2.160 IDI1
isopentenyl-diphosphate delta isomerase 1
chr17_-_80656461 2.158 NM_006822
RAB40B
RAB40B, member RAS oncogene family
chr4_-_2263706 2.148 NM_006454
MXD4
MAX dimerization protein 4
chr2_+_47630246 2.133 NM_000251
MSH2
mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli)
chr1_-_225615701 2.130 LBR
lamin B receptor
chr16_-_1832571 2.123 SPSB3
splA/ryanodine receptor domain and SOCS box containing 3
chr17_+_46018888 2.120 NM_018129
PNPO
pyridoxamine 5'-phosphate oxidase
chr1_+_227127993 2.101 ADCK3
aarF domain containing kinase 3
chr7_-_148725500 2.086 PDIA4
protein disulfide isomerase family A, member 4
chr15_-_69113213 2.080 ANP32A
acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
chr2_+_47630291 2.054 MSH2
mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli)
chr12_+_79258794 2.049 SYT1
synaptotagmin I
chr11_-_71159371 2.024 DHCR7
7-dehydrocholesterol reductase
chr7_+_155089614 2.015 INSIG1
insulin induced gene 1
chr15_-_71055745 2.012 NM_018003
UACA
uveal autoantigen with coiled-coil domains and ankyrin repeats
chr4_+_6271605 2.008 WFS1
Wolfram syndrome 1 (wolframin)
chr19_-_14629160 2.006 NM_006145
DNAJB1
DnaJ (Hsp40) homolog, subfamily B, member 1
chr1_-_55352818 2.002 DHCR24
24-dehydrocholesterol reductase
chr4_+_6271588 1.992 WFS1
Wolfram syndrome 1 (wolframin)
chr1_-_36022938 1.991 KIAA0319L
KIAA0319-like
chr16_+_8768403 1.990 NM_020686
ABAT
4-aminobutyrate aminotransferase
chr4_+_6271558 1.974 NM_001145853
NM_006005
WFS1

Wolfram syndrome 1 (wolframin)

chr17_+_26646120 1.963 NM_014573
TMEM97
transmembrane protein 97
chr5_+_172483285 1.954 NM_001168393
NM_001168394
NM_153607
C5orf41


chromosome 5 open reading frame 41


chr2_-_86116016 1.917 NM_003896
ST3GAL5
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
chr12_-_110011286 1.907 NM_052845
MMAB
methylmalonic aciduria (cobalamin deficiency) cblB type
chr11_-_71159442 1.903 NM_001163817
NM_001360
DHCR7

7-dehydrocholesterol reductase

chr10_-_93392857 1.902 NM_005398
PPP1R3C
protein phosphatase 1, regulatory subunit 3C
chr22_-_29137776 1.897 NM_001005735
NM_007194
NM_145862
CHEK2


checkpoint kinase 2


chr6_+_15246299 1.892 NM_004973
JARID2
jumonji, AT rich interactive domain 2
chr15_-_52587851 1.891 NM_018728
MYO5C
myosin VC
chr10_-_1095059 1.866 NM_004508
IDI1
isopentenyl-diphosphate delta isomerase 1
chr11_+_64879294 1.864 NM_003273
TM7SF2
transmembrane 7 superfamily member 2
chr19_-_6279927 1.862 NM_005934
MLLT1
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1
chr7_+_100136784 1.858 NM_006076
AGFG2
ArfGAP with FG repeats 2
chr1_+_52195508 1.856 OSBPL9
oxysterol binding protein-like 9
chr3_+_183165402 1.854 LOC100505687
uncharacterized LOC100505687
chr1_-_27339448 1.854 FAM46B
family with sequence similarity 46, member B
chr2_+_8822112 1.834 NM_002166
ID2
inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
chr1_-_46598250 1.831 NM_003629
NM_001114172
PIK3R3

phosphoinositide-3-kinase, regulatory subunit 3 (gamma)

chr1_+_52195458 1.818 NM_148904
NM_148905
NM_148907
OSBPL9


oxysterol binding protein-like 9


chr7_+_155089483 1.814 NM_005542
NM_198336
NM_198337
INSIG1


insulin induced gene 1


chrX_+_13671224 1.805 NM_152634
TCEANC
transcription elongation factor A (SII) N-terminal and central domain containing
chr11_-_124981458 1.805 TMEM218
transmembrane protein 218
chr8_-_103667882 1.801 NM_005655
KLF10
Kruppel-like factor 10
chr22_-_22089975 1.797 NM_013313
YPEL1
yippee-like 1 (Drosophila)
chr15_-_69113089 1.786 ANP32A
acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
chr1_+_44115828 1.784 KDM4A
lysine (K)-specific demethylase 4A
chr2_+_47630190 1.783 MSH2
mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli)
chr6_+_15245702 1.778 JARID2
jumonji, AT rich interactive domain 2
chr19_+_1249882 1.771 MIDN
midnolin
chr7_-_74306672 1.767 STAG3L2
stromal antigen 3-like 2
chr16_-_1661969 1.763 NM_014714
IFT140
intraflagellar transport 140 homolog (Chlamydomonas)
chr7_+_12727204 1.759 ARL4A
ADP-ribosylation factor-like 4A
chr2_-_128784864 1.754 NM_001145928
NM_024545
SAP130

Sin3A-associated protein, 130kDa

chr6_-_31830593 1.754 NM_000434
NEU1
sialidase 1 (lysosomal sialidase)
chr14_+_24584467 1.736 NM_181357
DCAF11
DDB1 and CUL4 associated factor 11
chr1_-_55352881 1.732 DHCR24
24-dehydrocholesterol reductase
chr4_+_156680125 1.706 NM_000857
GUCY1B3
guanylate cyclase 1, soluble, beta 3
chr6_-_31830551 1.702 NEU1
sialidase 1 (lysosomal sialidase)
chrX_+_46433191 1.701 NM_019886
CHST7
carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7
chr11_+_17298278 1.700 NM_005013
NUCB2
nucleobindin 2
chr11_-_2906960 1.696 NM_000076
NM_001122630
NM_001122631
CDKN1C


cyclin-dependent kinase inhibitor 1C (p57, Kip2)


chr6_+_42897184 1.682 CNPY3
canopy 3 homolog (zebrafish)
chr17_+_61554420 1.678 NM_000789
ACE
angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
chr15_-_70994608 1.671 NM_001008224
UACA
uveal autoantigen with coiled-coil domains and ankyrin repeats
chr7_+_115850546 1.661 NM_015641
TES
testis derived transcript (3 LIM domains)
chr1_-_36023005 1.660 NM_024874
KIAA0319L
KIAA0319-like
chr5_-_100238870 1.652 NM_175052
NM_005668
ST8SIA4

ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4

chr1_+_228645807 1.649 NM_175055
HIST3H2BB
histone cluster 3, H2bb
chr4_-_102268626 1.644 NM_000944
NM_001130691
NM_001130692
PPP3CA


protein phosphatase 3, catalytic subunit, alpha isozyme


chr12_+_110011616 1.640 MVK
mevalonate kinase
chr13_-_45992474 1.638 NM_001010875
SLC25A30
solute carrier family 25, member 30
chr12_-_6665220 1.636 NM_001039670
NM_001193457
NM_080730
IFFO1


intermediate filament family orphan 1


chrX_+_48380163 1.636 NM_006579
EBP
emopamil binding protein (sterol isomerase)
chr12_+_110011499 1.614 NM_000431
NM_001114185
MVK

mevalonate kinase

chr3_-_15900928 1.609 NM_015199
ANKRD28
ankyrin repeat domain 28
chr1_+_185703470 1.599 NM_031935
HMCN1
hemicentin 1
chr2_+_177053306 1.599 NM_024501
HOXD1
homeobox D1
chr3_-_105587710 1.590 NM_170662
CBLB
Cas-Br-M (murine) ecotropic retroviral transforming sequence b
chr12_-_123717645 1.589 MPHOSPH9
M-phase phosphoprotein 9
chr14_+_24583905 1.580 NM_001163484
DCAF11
DDB1 and CUL4 associated factor 11
chr7_-_121784236 1.579 NM_005763
AASS
aminoadipate-semialdehyde synthase
chr8_+_97506020 1.571 SDC2
syndecan 2

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.91 2.19e-12 GO:0007049 cell cycle
2.09 3.65e-11 GO:0022403 cell cycle phase
1.97 8.71e-11 GO:0022402 cell cycle process
6.52 9.55e-11 GO:0016126 sterol biosynthetic process
2.31 1.39e-10 GO:0006325 chromatin organization
7.04 1.79e-10 GO:0006695 cholesterol biosynthetic process
2.12 1.88e-10 GO:0051276 chromosome organization
2.34 3.32e-10 GO:0000279 M phase
3.82 1.39e-09 GO:0065004 protein-DNA complex assembly
3.95 2.18e-09 GO:0031497 chromatin assembly
4.04 2.24e-09 GO:0006334 nucleosome assembly
3.46 5.71e-09 GO:0006323 DNA packaging
1.60 6.35e-09 GO:0006996 organelle organization
3.62 8.93e-09 GO:0071824 protein-DNA complex subunit organization
3.75 1.12e-08 GO:0034728 nucleosome organization
1.24 2.65e-08 GO:0044237 cellular metabolic process
2.03 3.53e-08 GO:0000278 mitotic cell cycle
1.44 4.66e-08 GO:0009058 biosynthetic process
3.25 4.71e-08 GO:0006333 chromatin assembly or disassembly
3.12 6.26e-08 GO:0071103 DNA conformation change
1.12 1.96e-07 GO:0009987 cellular process
1.98 2.42e-07 GO:0006259 DNA metabolic process
3.45 2.15e-06 GO:0006694 steroid biosynthetic process
2.32 2.33e-06 GO:0000087 M phase of mitotic cell cycle
1.19 2.43e-06 GO:0008152 metabolic process
1.21 2.89e-06 GO:0044238 primary metabolic process
1.40 3.46e-06 GO:0044249 cellular biosynthetic process
1.42 4.17e-06 GO:0090304 nucleic acid metabolic process
2.20 6.60e-06 GO:0006281 DNA repair
1.33 7.12e-06 GO:0034641 cellular nitrogen compound metabolic process
1.32 1.37e-05 GO:0006807 nitrogen compound metabolic process
1.26 2.08e-05 GO:0044260 cellular macromolecule metabolic process
2.84 4.52e-05 GO:0006310 DNA recombination
1.35 8.50e-05 GO:0071842 cellular component organization at cellular level
10.01 8.56e-05 GO:0002566 somatic diversification of immune receptors via somatic mutation
10.01 8.56e-05 GO:0016446 somatic hypermutation of immunoglobulin genes
2.19 1.10e-04 GO:0000280 nuclear division
2.19 1.10e-04 GO:0007067 mitosis
1.33 1.24e-04 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.04 1.58e-04 GO:0034622 cellular macromolecular complex assembly
3.04 2.83e-04 GO:0016125 sterol metabolic process
2.03 2.92e-04 GO:0051301 cell division
1.41 3.01e-04 GO:0044281 small molecule metabolic process
2.12 3.33e-04 GO:0048285 organelle fission
1.86 3.55e-04 GO:0034621 cellular macromolecular complex subunit organization
1.63 4.80e-04 GO:0033554 cellular response to stress
1.97 5.15e-04 GO:0008610 lipid biosynthetic process
1.98 7.66e-04 GO:0016568 chromatin modification
3.03 9.13e-04 GO:0008203 cholesterol metabolic process
1.31 1.10e-03 GO:0071841 cellular component organization or biogenesis at cellular level
1.79 1.19e-03 GO:0006974 response to DNA damage stimulus
1.61 1.21e-03 GO:0043933 macromolecular complex subunit organization
1.67 1.25e-03 GO:0065003 macromolecular complex assembly
1.26 1.40e-03 GO:0031323 regulation of cellular metabolic process
2.26 1.43e-03 GO:0000075 cell cycle checkpoint
3.12 1.48e-03 GO:0000236 mitotic prometaphase
2.23 1.56e-03 GO:0071156 regulation of cell cycle arrest
1.26 1.79e-03 GO:0080090 regulation of primary metabolic process
1.95 2.33e-03 GO:0010564 regulation of cell cycle process
1.26 2.54e-03 GO:0016043 cellular component organization
1.69 2.81e-03 GO:0051726 regulation of cell cycle
2.01 3.02e-03 GO:0051325 interphase
1.23 3.25e-03 GO:0019222 regulation of metabolic process
1.19 6.39e-03 GO:0043170 macromolecule metabolic process
5.63 6.47e-03 GO:0008299 isoprenoid biosynthetic process
1.96 9.39e-03 GO:0051329 interphase of mitotic cell cycle
1.24 1.86e-02 GO:0060255 regulation of macromolecule metabolic process
2.58 2.12e-02 GO:0007126 meiosis
2.58 2.12e-02 GO:0051327 M phase of meiotic cell cycle
1.29 2.36e-02 GO:2000112 regulation of cellular macromolecule biosynthetic process
2.56 2.51e-02 GO:0051321 meiotic cell cycle
1.23 2.76e-02 GO:0071840 cellular component organization or biogenesis
1.50 2.87e-02 GO:0055114 oxidation-reduction process
2.35 4.10e-02 GO:0016054 organic acid catabolic process
2.35 4.10e-02 GO:0046395 carboxylic acid catabolic process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.30 1.83e-39 GO:0043229 intracellular organelle
1.24 2.37e-39 GO:0044424 intracellular part
1.30 5.13e-39 GO:0043226 organelle
1.22 7.74e-38 GO:0005622 intracellular
1.32 6.35e-36 GO:0043227 membrane-bounded organelle
1.32 7.45e-36 GO:0043231 intracellular membrane-bounded organelle
1.43 8.63e-27 GO:0005634 nucleus
1.41 7.97e-25 GO:0044446 intracellular organelle part
1.40 5.71e-24 GO:0044422 organelle part
2.39 7.98e-16 GO:0005694 chromosome
1.61 1.22e-15 GO:0070013 intracellular organelle lumen
1.59 6.23e-15 GO:0043233 organelle lumen
1.57 1.89e-14 GO:0031974 membrane-enclosed lumen
2.44 6.08e-14 GO:0044427 chromosomal part
1.57 4.20e-13 GO:0044428 nuclear part
1.20 1.94e-11 GO:0005737 cytoplasm
2.84 6.69e-11 GO:0000785 chromatin
1.55 4.94e-10 GO:0031981 nuclear lumen
1.65 1.92e-09 GO:0005654 nucleoplasm
1.35 3.56e-09 GO:0032991 macromolecular complex
1.24 5.55e-09 GO:0044444 cytoplasmic part
3.67 3.02e-08 GO:0032993 protein-DNA complex
4.50 3.38e-08 GO:0000786 nucleosome
1.38 1.42e-07 GO:0043228 non-membrane-bounded organelle
1.38 1.42e-07 GO:0043232 intracellular non-membrane-bounded organelle
1.05 7.68e-05 GO:0044464 cell part
1.05 7.96e-05 GO:0005623 cell
1.30 8.35e-05 GO:0043234 protein complex
1.47 1.11e-04 GO:0005739 mitochondrion
2.54 3.00e-04 GO:0000775 chromosome, centromeric region
1.65 4.38e-04 GO:0015630 microtubule cytoskeleton
1.63 8.02e-04 GO:0044429 mitochondrial part
2.25 2.39e-03 GO:0044454 nuclear chromosome part
2.04 7.96e-03 GO:0000228 nuclear chromosome
1.94 8.49e-03 GO:0005759 mitochondrial matrix
6.57 1.02e-02 GO:0032300 mismatch repair complex
1.53 1.05e-02 GO:0031967 organelle envelope
9.38 1.36e-02 GO:0032389 MutLalpha complex
2.27 1.37e-02 GO:0000793 condensed chromosome
3.57 1.49e-02 GO:0008287 protein serine/threonine phosphatase complex
1.51 2.06e-02 GO:0031975 envelope
1.27 2.84e-02 GO:0005829 cytosol
2.82 3.06e-02 GO:0034399 nuclear periphery
1.47 4.45e-02 GO:0044432 endoplasmic reticulum part
2.63 4.86e-02 GO:0000779 condensed chromosome, centromeric region

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.13 8.72e-13 GO:0005488 binding
1.46 4.39e-09 GO:0003677 DNA binding
1.33 2.12e-07 GO:0003676 nucleic acid binding
1.18 5.86e-07 GO:0005515 protein binding
9.65 2.09e-03 GO:0032404 mismatch repair complex binding
6.43 4.66e-03 GO:0030983 mismatched DNA binding
9.38 2.03e-02 GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water
1.41 4.84e-02 GO:0030528 transcription regulator activity
5.00 4.91e-02 GO:0008601 protein phosphatase type 2A regulator activity