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Motif ID: NKX3-2.p2

Z-value: 1.013

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr16_+_57406398	6.824	NM_002996	CX3CL1	chemokine (C-X3-C motif) ligand 1
chr5_+_118604504	6.124		TNFAIP8	tumor necrosis factor, alpha-induced protein 8
chr5_+_118604417	5.992	NM_001077654	TNFAIP8	tumor necrosis factor, alpha-induced protein 8
chr2_+_102979096	4.116	NM_003855	IL18R1	interleukin 18 receptor 1
chr6_-_31550065	3.434	NM_002341 NM_009588	LTB	lymphotoxin beta (TNF superfamily, member 3)
chr2_+_228678556	3.377	NM_001130046 NM_004591	CCL20	chemokine (C-C motif) ligand 20
chr1_-_169703178	2.608	NM_000450	SELE	selectin E
chr1_+_101185195	2.607	NM_001078 NM_001199834 NM_080682	VCAM1	vascular cell adhesion molecule 1
chr5_+_131409484	2.143	NM_000758	CSF2	colony stimulating factor 2 (granulocyte-macrophage)
chr15_+_67358161	1.968		SMAD3	SMAD family member 3
chr5_-_150467220	1.950	NM_001252390	TNIP1	TNFAIP3 interacting protein 1
chr1_-_95007139	1.844	NM_001178096 NM_001993	F3	coagulation factor III (thromboplastin, tissue factor)
chr3_+_53195214	1.773	NM_006254 NM_212539	PRKCD	protein kinase C, delta
chr5_-_150466696	1.765	NM_001252391 NM_001252392	TNIP1	TNFAIP3 interacting protein 1
chr8_+_123793894	1.661	NM_014943	ZHX2	zinc fingers and homeoboxes 2
chr8_+_123793988	1.602		ZHX2	zinc fingers and homeoboxes 2
chr19_+_676346	1.507	NM_005860	FSTL3	follistatin-like 3 (secreted glycoprotein)
chr8_+_123794043	1.505		ZHX2	zinc fingers and homeoboxes 2
chr11_-_8892909	1.462		ST5	suppression of tumorigenicity 5
chr11_-_128457452	1.417	NM_001143820	ETS1	v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)
chr15_+_67358194	1.379	NM_005902	SMAD3	SMAD family member 3
chr2_+_150187028	1.298	NM_194317	LYPD6	LY6/PLAUR domain containing 6
chr21_+_43639202	1.262	NM_004915 NM_016818	ABCG1	ATP-binding cassette, sub-family G (WHITE), member 1
chr1_+_212738675	1.188	NM_001030287	ATF3	activating transcription factor 3
chr16_-_11680756	1.180	NM_001136472 NM_001136473	LITAF	lipopolysaccharide-induced TNF factor
chr10_+_104154228	1.148	NM_001077493 NM_001077494	NFKB2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
chr20_+_55966440	1.129	NM_017495 NM_183425	RBM38	RNA binding motif protein 38
chr6_-_32821743	1.100	NM_000593	TAP1	transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
chr7_+_18126543	1.089	NM_001204144	HDAC9	histone deacetylase 9
chr5_-_121412805	1.067	NM_001178102	LOX	lysyl oxidase
chr3_-_182880463	1.062	NM_014398	LAMP3	lysosomal-associated membrane protein 3
chr12_-_57504935	1.018		STAT6	signal transducer and activator of transcription 6, interleukin-4 induced
chr1_-_173176314	1.009	NM_003326	TNFSF4	tumor necrosis factor (ligand) superfamily, member 4
chr11_-_72380107	1.003	NM_001146209	PDE2A	phosphodiesterase 2A, cGMP-stimulated
chr10_+_6244839	1.003	NM_004566	PFKFB3	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
chr14_+_55168831	1.001		SAMD4A	sterile alpha motif domain containing 4A
chr6_+_80340971	0.982	NM_031469	SH3BGRL2	SH3 domain binding glutamic acid-rich protein like 2
chr20_+_53092131	0.978	NM_018431	DOK5	docking protein 5
chr1_+_218519576	0.973		TGFB2	transforming growth factor, beta 2
chr1_+_218518675	0.968	NM_001135599 NM_003238	TGFB2	transforming growth factor, beta 2
chr3_-_107809754	0.930	NM_001777 NM_198793	CD47	CD47 molecule
chr11_-_8739398	0.927		ST5	suppression of tumorigenicity 5
chr17_+_25958245	0.901		LGALS9	lectin, galactoside-binding, soluble, 9
chr4_-_122148620	0.898	NM_001244764	TNIP3	TNFAIP3 interacting protein 3
chr6_+_160148608	0.896	NM_152857	WTAP	Wilms tumor 1 associated protein
chr19_+_45251933	0.875	NM_005178	BCL3	B-cell CLL/lymphoma 3
chr14_+_104605441	0.863		KIF26A	kinesin family member 26A
chr13_-_26625164	0.862	NM_001007538	SHISA2	shisa homolog 2 (Xenopus laevis)
chr2_-_145277879	0.853	NM_001171653 NM_014795	ZEB2	zinc finger E-box binding homeobox 2
chr7_+_28475233	0.842	NM_004904	CREB5	cAMP responsive element binding protein 5
chr11_+_19372270	0.840	NM_001111018	NAV2	neuron navigator 2
chr10_+_91087601	0.834	NM_001549	IFIT3	interferon-induced protein with tetratricopeptide repeats 3
chr3_+_105085740	0.831		ALCAM	activated leukocyte cell adhesion molecule
chr14_-_35344450	0.826		BAZ1A	bromodomain adjacent to zinc finger domain, 1A
chr14_-_35344526	0.808		BAZ1A	bromodomain adjacent to zinc finger domain, 1A
chr11_-_4414887	0.798	NM_003141	TRIM21	tripartite motif containing 21
chr9_-_38069082	0.788		SHB	Src homology 2 domain containing adaptor protein B
chr14_-_35344490	0.786		BAZ1A	bromodomain adjacent to zinc finger domain, 1A
chr5_+_52776479	0.784		FST	follistatin
chr7_+_28530747	0.783		CREB5	cAMP responsive element binding protein 5
chr11_-_125933186	0.756	NM_001243597 NM_016952	CDON	Cdon homolog (mouse)
chr15_-_74726258	0.754	NM_001146029 NM_003612	SEMA7A	semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group)
chr1_-_57045129	0.753		PPAP2B	phosphatidic acid phosphatase type 2B
chr3_+_105085553	0.751	NM_001243280 NM_001243281 NM_001243283 NM_001627	ALCAM	activated leukocyte cell adhesion molecule
chr2_+_102770401	0.747	NM_000877	IL1R1	interleukin 1 receptor, type I
chr14_+_103589711	0.743		TNFAIP2	tumor necrosis factor, alpha-induced protein 2
chr3_-_71114006	0.739	NM_001244813	FOXP1	forkhead box P1
chr13_+_26828755	0.728	NM_001260	CDK8	cyclin-dependent kinase 8
chr7_-_22396511	0.725	NM_012294	RAPGEF5	Rap guanine nucleotide exchange factor (GEF) 5
chr1_+_212782103	0.721		ATF3	activating transcription factor 3
chr5_+_52776408	0.720		FST	follistatin
chr17_-_15244898	0.717	NM_031898	TEKT3	tektin 3
chr1_+_36554452	0.709	NM_017825	ADPRHL2	ADP-ribosylhydrolase like 2
chr2_-_145277568	0.708		ZEB2	zinc finger E-box binding homeobox 2
chr4_-_7436614	0.704	NM_001085382	PSAPL1	prosaposin-like 1 (gene/pseudogene)
chr3_-_45267068	0.703		TMEM158	transmembrane protein 158 (gene/pseudogene)
chr1_-_173020011	0.700	NM_005092	TNFSF18	tumor necrosis factor (ligand) superfamily, member 18
chr10_+_96305521	0.700	NM_018063	HELLS	helicase, lymphoid-specific
chr17_+_7348362	0.690	NM_000747	CHRNB1	cholinergic receptor, nicotinic, beta 1 (muscle)
chr2_-_37899227	0.670	NM_006449	CDC42EP3	CDC42 effector protein (Rho GTPase binding) 3
chr14_+_104605059	0.669	NM_015656	KIF26A	kinesin family member 26A
chr12_-_57505176	0.667	NM_001178078 NM_001178080 NM_001178081 NM_003153	STAT6	signal transducer and activator of transcription 6, interleukin-4 induced
chr5_+_56110899	0.656	NM_005921	MAP3K1	mitogen-activated protein kinase kinase kinase 1
chr12_-_57505121	0.654		STAT6	signal transducer and activator of transcription 6, interleukin-4 induced
chr2_+_219433517	0.652	NM_005444	RQCD1	RCD1 required for cell differentiation1 homolog (S. pombe)
chrX_-_68385249	0.650	NM_001032396 NM_022368 NM_145119	PJA1	praja ring finger 1
chr6_+_158438079	0.639	NM_001178088	SYNJ2	synaptojanin 2
chr20_-_61557818	0.631		DIDO1	death inducer-obliterator 1
chr22_+_41697452	0.630	NM_017590	ZC3H7B	zinc finger CCCH-type containing 7B
chr17_+_7255427	0.628		KCTD11	potassium channel tetramerisation domain containing 11
chr8_+_86099909	0.627	NM_001083589	E2F5	E2F transcription factor 5, p130-binding
chr6_+_29855506	0.625
chr5_-_149669400	0.617	NM_015981 NM_171825	CAMK2A	calcium/calmodulin-dependent protein kinase II alpha
chr10_+_73571639	0.599	NM_001171935 NM_001171936	CDH23	cadherin-related 23
chr5_+_68530621	0.595	NM_001799	CDK7	cyclin-dependent kinase 7
chr14_-_76448091	0.595	NM_003239	TGFB3	transforming growth factor, beta 3
chr14_-_24616429	0.592		PSME2	proteasome (prosome, macropain) activator subunit 2 (PA28 beta)
chr18_+_32073343	0.591		DTNA	dystrobrevin, alpha
chr6_+_160148145	0.590	NM_004906 NM_152858	WTAP	Wilms tumor 1 associated protein
chr2_-_69098502	0.589	NM_014482	BMP10	bone morphogenetic protein 10
chrX_-_83757398	0.586	NM_001177478 NM_001177479 NM_144657	HDX	highly divergent homeobox
chr16_+_75600276	0.576		GABARAPL2	GABA(A) receptor-associated protein-like 2
chr1_-_117113593	0.575		CD58	CD58 molecule
chr14_-_35344080	0.574		BAZ1A	bromodomain adjacent to zinc finger domain, 1A
chr8_+_104310660	0.571	NM_001164615	FZD6	frizzled family receptor 6
chr2_-_175869910	0.570	NM_001822 NM_001025201	CHN1	chimerin (chimaerin) 1
chr21_+_43710190	0.570		ABCG1	ATP-binding cassette, sub-family G (WHITE), member 1
chr3_-_52008012	0.569		ABHD14B	abhydrolase domain containing 14B
chr6_+_29974352	0.568		HLA-J	major histocompatibility complex, class I, J (pseudogene)
chr11_+_20070609	0.560		NAV2	neuron navigator 2
chr6_-_31324955	0.559		HLA-B	major histocompatibility complex, class I, B
chr5_+_56471272	0.559	NM_001127235	GPBP1	GC-rich promoter binding protein 1
chr13_+_97928196	0.555		MBNL2	muscleblind-like 2 (Drosophila)
chr6_-_31324898	0.553		HLA-B	major histocompatibility complex, class I, B
chr1_-_45308603	0.546	NM_001166292 NM_003738	PTCH2	patched 2
chr10_-_121632265	0.544	NM_024834	MCMBP	minichromosome maintenance complex binding protein
chr5_-_131826426	0.540	NM_002198	IRF1	interferon regulatory factor 1
chr12_-_51422012	0.531	NM_001174125	SLC11A2	solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2
chr19_-_36705982	0.526	NM_001042474	ZNF565	zinc finger protein 565
chr17_+_25958151	0.525	NM_002308 NM_009587	LGALS9	lectin, galactoside-binding, soluble, 9
chr20_-_10654139	0.523		JAG1	jagged 1
chr1_-_117113640	0.520	NM_001144822 NM_001779	CD58	CD58 molecule
chr16_+_75600248	0.517	NM_007285	GABARAPL2	GABA(A) receptor-associated protein-like 2
chr6_-_31324975	0.516	NM_005514	HLA-B	major histocompatibility complex, class I, B
chr1_-_150738255	0.513		CTSS	cathepsin S
chr5_-_54830369	0.512	NM_003711 NM_176895	RNF138P1 PPAP2A	ring finger protein 138 pseudogene 1 phosphatidic acid phosphatase type 2A
chr6_+_111303240	0.511	NM_032194	RPF2	ribosome production factor 2 homolog (S. cerevisiae)
chr7_+_28725597	0.508	NM_001011666	CREB5	cAMP responsive element binding protein 5
chr17_+_25958217	0.503		LGALS9	lectin, galactoside-binding, soluble, 9
chr17_+_25958192	0.503		LGALS9	lectin, galactoside-binding, soluble, 9
chr1_-_159895279	0.498	NM_003564	TAGLN2	transgelin 2
chr5_-_179780314	0.496	NM_005110	GFPT2	glutamine-fructose-6-phosphate transaminase 2
chr1_+_222886728	0.492		BROX	BRO1 domain and CAAX motif containing
chr3_-_187454247	0.490	NM_001130845	BCL6	B-cell CLL/lymphoma 6
chr1_-_57045214	0.485		PPAP2B	phosphatidic acid phosphatase type 2B
chr1_-_57045235	0.484	NM_003713	PPAP2B	phosphatidic acid phosphatase type 2B
chr1_+_100818007	0.483	NM_003672 NM_033312 NM_033313	CDC14A	CDC14 cell division cycle 14 homolog A (S. cerevisiae)
chr11_-_57089670	0.483		TNKS1BP1	tankyrase 1 binding protein 1, 182kDa
chr17_+_45810609	0.474	NM_013351	TBX21	T-box 21
chr14_-_91720166	0.473	NM_003485	GPR68	G protein-coupled receptor 68
chr12_+_54891539	0.467		NCKAP1L	NCK-associated protein 1-like
chr17_+_41158741	0.466	NM_005533	IFI35	interferon-induced protein 35
chr1_-_27930360	0.465		AHDC1	AT hook, DNA binding motif, containing 1
chr10_+_98592658	0.464	NM_032440	LCOR	ligand dependent nuclear receptor corepressor
chr8_-_122653493	0.463	NM_005328	HAS2	hyaluronan synthase 2
chr7_+_18548899	0.461	NM_001204147 NM_001204148	HDAC9	histone deacetylase 9
chr10_+_72575724	0.460		SGPL1	sphingosine-1-phosphate lyase 1
chr11_-_8832881	0.459	NM_139157	ST5	suppression of tumorigenicity 5
chr21_-_16437125	0.459	NM_003489	NRIP1	nuclear receptor interacting protein 1
chr2_+_150186498	0.458	NM_001195685	LYPD6	LY6/PLAUR domain containing 6
chr9_-_85882093	0.457	NM_001244962	FRMD3	FERM domain containing 3
chr7_-_25019625	0.452	NM_015550 NM_145320 NM_145321 NM_145322	OSBPL3	oxysterol binding protein-like 3
chr3_+_121774208	0.452	NM_001206924 NM_001206925 NM_175862	CD86	CD86 molecule
chr10_+_73555527	0.451	NM_001171933 NM_001171934	CDH23	cadherin-related 23
chr5_-_149669187	0.448		CAMK2A	calcium/calmodulin-dependent protein kinase II alpha
chr1_+_46972667	0.445	NM_147192 NM_172225	DMBX1	diencephalon/mesencephalon homeobox 1
chr11_-_128392061	0.443	NM_001162422 NM_005238	ETS1	v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)
chr3_-_192635933	0.442	NM_178496	MB21D2	Mab-21 domain containing 2
chr1_+_16174358	0.440	NM_015001	SPEN	spen homolog, transcriptional regulator (Drosophila)
chr2_+_187454724	0.438	NM_001145000 NM_002210	ITGAV	integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)
chr14_-_24047428	0.426		JPH4	junctophilin 4
chr19_+_16999807	0.422	NM_003950	F2RL3	coagulation factor II (thrombin) receptor-like 3
chr3_+_9773769	0.419		BRPF1	bromodomain and PHD finger containing, 1
chr17_-_32690180	0.417	NM_002981	CCL1	chemokine (C-C motif) ligand 1
chr3_-_71592707	0.415	NM_001244816	FOXP1	forkhead box P1
chr1_-_111743261	0.412	NM_024901	DENND2D	DENN/MADD domain containing 2D
chr6_+_26440699	0.412	NM_001242803 NM_006994 NM_197974	BTN3A3	butyrophilin, subfamily 3, member A3
chr3_-_79817058	0.411	NM_002941	ROBO1	roundabout, axon guidance receptor, homolog 1 (Drosophila)
chr20_-_3996035	0.406	NM_007219 NM_001134337 NM_001134338	RNF24	ring finger protein 24
chr5_-_126366068	0.405		MARCH3	membrane-associated ring finger (C3HC4) 3
chr11_+_65479685	0.402		KAT5	K(lysine) acetyltransferase 5
chr14_-_35344852	0.401	NM_013448 NM_182648	BAZ1A	bromodomain adjacent to zinc finger domain, 1A
chr9_+_116930778	0.401		COL27A1	collagen, type XXVII, alpha 1
chr10_-_7451198	0.400	NM_001018039	SFMBT2	Scm-like with four mbt domains 2
chr16_+_83986826	0.399	NM_182981	OSGIN1	oxidative stress induced growth inhibitor 1
chr3_-_190040192	0.399	NM_021101	CLDN1	claudin 1
chr17_+_39261640	0.395	NM_001146041	KRTAP4-9	keratin associated protein 4-9
chr3_+_9691198	0.390		MTMR14	myotubularin related protein 14
chr1_-_159895258	0.389		TAGLN2	transgelin 2
chr5_-_158636489	0.388	NM_001199383	RNF145	ring finger protein 145
chr6_+_70576447	0.388	NM_001858	COL19A1	collagen, type XIX, alpha 1
chr9_+_118916069	0.388	NM_002581	PAPPA	pregnancy-associated plasma protein A, pappalysin 1
chr16_+_4674819	0.388	NM_001142289 NM_001142290 NM_001142291 NM_015246	MGRN1	mahogunin, ring finger 1
chr1_+_46646199	0.386		TSPAN1	tetraspanin 1
chr17_-_41739261	0.385	NM_001040002	MEOX1	mesenchyme homeobox 1
chr1_-_209825673	0.383	NM_001127641	LAMB3	laminin, beta 3
chr1_-_111743297	0.383		DENND2D	DENN/MADD domain containing 2D
chr5_+_125695787	0.381	NM_001146319	GRAMD3	GRAM domain containing 3
chr3_+_9691184	0.381		MTMR14	myotubularin related protein 14
chr5_+_38445577	0.378	NM_182801	EGFLAM	EGF-like, fibronectin type III and laminin G domains
chr6_-_86352564	0.378	NM_001159674 NM_001253771	SYNCRIP	synaptotagmin binding, cytoplasmic RNA interacting protein
chr5_-_35048239	0.374	NM_031900	AGXT2	alanine--glyoxylate aminotransferase 2
chr12_-_133338389	0.374	NM_015114	ANKLE2	ankyrin repeat and LEM domain containing 2
chr9_+_34989637	0.374	NM_001135004 NM_012266	DNAJB5	DnaJ (Hsp40) homolog, subfamily B, member 5
chr6_-_40555111	0.372	NM_020737	LRFN2	leucine rich repeat and fibronectin type III domain containing 2
chr2_-_153573858	0.371	NM_017892	PRPF40A	PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae)
chr13_+_97928414	0.371		MBNL2	muscleblind-like 2 (Drosophila)
chr5_+_68530713	0.370		CDK7	cyclin-dependent kinase 7
chr12_+_21168629	0.369	NM_001009562	SLCO1B7	solute carrier organic anion transporter family, member 1B7 (non-functional)
chr3_+_77089248	0.367	NM_002942	ROBO2	roundabout, axon guidance receptor, homolog 2 (Drosophila)

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.10	7.17e-10	GO:0009987	cellular process
1.27	6.20e-06	GO:0048518	positive regulation of biological process
1.27	2.60e-05	GO:0048522	positive regulation of cellular process
1.18	2.08e-03	GO:0023052	signaling
1.16	4.14e-03	GO:0044260	cellular macromolecule metabolic process
1.51	4.76e-03	GO:0006928	cellular component movement
1.10	6.05e-03	GO:0065007	biological regulation
1.10	6.88e-03	GO:0050789	regulation of biological process
1.22	9.40e-03	GO:0048519	negative regulation of biological process
1.29	1.09e-02	GO:0007399	nervous system development
1.17	1.61e-02	GO:0007165	signal transduction
1.14	1.79e-02	GO:0043170	macromolecule metabolic process
1.35	2.47e-02	GO:0042127	regulation of cell proliferation
1.17	2.63e-02	GO:0051179	localization
1.24	2.75e-02	GO:0010467	gene expression
1.41	3.27e-02	GO:0006915	apoptosis
1.56	3.88e-02	GO:0010627	regulation of intracellular protein kinase cascade
1.48	4.68e-02	GO:0009967	positive regulation of signal transduction
1.39	4.83e-02	GO:0012501	programmed cell death

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.06	7.11e-03	GO:0044424	intracellular part
1.08	7.93e-03	GO:0005737	cytoplasm
1.21	1.40e-02	GO:0005829	cytosol
1.05	4.59e-02	GO:0005622	intracellular

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.21	3.39e-18	GO:0005515	protein binding
1.07	7.84e-06	GO:0005488	binding