Motif ID: NR4A2.p2

Z-value: 0.731


Transcription factors associated with NR4A2.p2:

monomer

Gene SymbolEntrez IDGene Name
NR4A2 4929 nuclear receptor subfamily 4, group A, member 2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.p-valuePlot
NR4A2chr2_-_1571890400.029.3e-01Click!


Activity profile for motif NR4A2.p2.

activity profile for motif NR4A2.p2


Sorted Z-values histogram for motif NR4A2.p2

Sorted Z-values for motif NR4A2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NR4A2.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr12_-_16759531 1.528 NM_018640
LMO3
LIM domain only 3 (rhombotin-like 2)
chr12_-_16759430 1.409 LMO3
LIM domain only 3 (rhombotin-like 2)
chr12_-_16759939 1.089 NM_001243613
LMO3
LIM domain only 3 (rhombotin-like 2)
chr3_-_123339178 0.944 MYLK
myosin light chain kinase
chr3_-_123339423 0.911 NM_053031
NM_053032
MYLK

myosin light chain kinase

chr12_-_16759733 0.818 NM_001243610
LMO3
LIM domain only 3 (rhombotin-like 2)
chr12_-_16758839 0.772 NM_001243612
LMO3
LIM domain only 3 (rhombotin-like 2)
chr12_+_78225068 0.764 NM_014903
NAV3
neuron navigator 3
chr12_-_16760935 0.736 NM_001001395
NM_001243609
LMO3

LIM domain only 3 (rhombotin-like 2)

chr4_+_81118639 0.721 NM_001099403
PRDM8
PR domain containing 8
chr12_+_56075329 0.709 NM_152637
METTL7B
methyltransferase like 7B
chr12_+_56075418 0.696 METTL7B
methyltransferase like 7B
chr20_+_44486219 0.643 NM_080752
ZSWIM3
zinc finger, SWIM-type containing 3
chr17_+_7533452 0.610 NM_001040
NM_001146279
NM_001146280
NM_001146281
SHBG



sex hormone-binding globulin



chr11_+_69455837 0.590 NM_053056
CCND1
cyclin D1
chr19_+_3880660 0.569 ATCAY
ataxia, cerebellar, Cayman type
chr19_+_3880617 0.533 NM_033064
ATCAY
ataxia, cerebellar, Cayman type
chr22_-_30960875 0.526 NM_004861
GAL3ST1
galactose-3-O-sulfotransferase 1
chr6_-_119470336 0.525 NM_001100411
FAM184A
family with sequence similarity 184, member A
chr2_+_219745243 0.511 NM_025216
WNT10A
wingless-type MMTV integration site family, member 10A

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 22 entries
enrichment   p-value GO term description
1.55 4.26e-02 GO:0046903 secretion
1.51 3.90e-04 GO:0007267 cell-cell signaling
1.47 3.36e-05 GO:0007154 cell communication
1.44 1.35e-03 GO:0006811 ion transport
1.41 1.53e-02 GO:0044093 positive regulation of molecular function
1.36 3.22e-02 GO:0009605 response to external stimulus
1.28 7.15e-03 GO:0007166 cell surface receptor linked signaling pathway
1.25 6.72e-03 GO:0065008 regulation of biological quality
1.24 1.37e-06 GO:0023052 signaling
1.24 3.79e-02 GO:0030154 cell differentiation
1.23 6.26e-05 GO:0007165 signal transduction
1.22 1.66e-03 GO:0006810 transport
1.22 2.40e-03 GO:0051234 establishment of localization
1.21 2.67e-02 GO:0048518 positive regulation of biological process
1.20 8.07e-04 GO:0051179 localization
1.18 1.17e-03 GO:0051716 cellular response to stimulus
1.17 1.86e-02 GO:0032502 developmental process
1.14 8.08e-03 GO:0032501 multicellular organismal process
1.12 9.09e-05 GO:0065007 biological regulation
1.12 6.13e-04 GO:0050789 regulation of biological process

Gene overrepresentation in compartment category:

Showing 1 to 5 of 5 entries
enrichment   p-value GO term description
1.77 1.32e-02 GO:0030141 stored secretory granule
1.39 4.16e-03 GO:0005626 insoluble fraction
1.37 1.35e-02 GO:0005624 membrane fraction
1.33 4.71e-03 GO:0000267 cell fraction
1.24 1.16e-03 GO:0044459 plasma membrane part

Gene overrepresentation in function category:

Showing 1 to 9 of 9 entries
enrichment   p-value GO term description
2.08 9.86e-04 GO:0008509 anion transmembrane transporter activity
1.48 2.18e-04 GO:0015075 ion transmembrane transporter activity
1.41 1.15e-03 GO:0022891 substrate-specific transmembrane transporter activity
1.40 7.60e-04 GO:0022857 transmembrane transporter activity
1.37 1.69e-03 GO:0022892 substrate-specific transporter activity
1.37 4.37e-02 GO:0019899 enzyme binding
1.29 3.93e-02 GO:0005215 transporter activity
1.13 1.74e-05 GO:0005515 protein binding
1.06 1.06e-02 GO:0005488 binding