Motif ID: NR5A1,2.p2

Z-value: 0.921


Transcription factors associated with NR5A1,2.p2:

Gene SymbolEntrez IDGene Name
NR5A1 2516 nuclear receptor subfamily 5, group A, member 1
NR5A2 2494 nuclear receptor subfamily 5, group A, member 2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.p-valuePlot
NR5A1chr9_-_1272696890.125.8e-01Click!
NR5A2chr1_+_199996729-0.009.9e-01Click!


Activity profile for motif NR5A1,2.p2.

activity profile for motif NR5A1,2.p2


Sorted Z-values histogram for motif NR5A1,2.p2

Sorted Z-values for motif NR5A1,2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NR5A1,2.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr13_-_33859835 1.559 NM_178006
 STARD13
StAR-related lipid transfer (START) domain containing 13
chr3_-_123339178 1.301 MYLK
myosin light chain kinase
chr12_-_10151689 1.261 NM_001099431
NM_016509
 CLEC1B

C-type lectin domain family 1, member B

chr9_+_72658735 1.231 MAMDC2
MAM domain containing 2
chr3_-_123339423 1.125 NM_053031
NM_053032
 MYLK

myosin light chain kinase

chr11_+_71710662 0.910 NM_001145057
 IL18BP
interleukin 18 binding protein
chr22_+_31518923 0.908 NM_001002837
 INPP5J
inositol polyphosphate-5-phosphatase J
chr21_+_42792441 0.773 NM_001144925
 MX1
myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse)
chr18_-_46469118 0.739 NM_001190823
 SMAD7
SMAD family member 7
chr5_-_172755418 0.734 STC2
stanniocalcin 2
chr12_-_106532447 0.698 NUAK1
NUAK family, SNF1-like kinase, 1
chr11_-_27741192 0.694 NM_001143807
 BDNF
brain-derived neurotrophic factor
chr6_+_132891460 0.693 NM_175067
 TAAR6
trace amine associated receptor 6
chr12_+_52626953 0.631 NM_005556
 KRT7
keratin 7
chr20_+_18794369 0.627 NM_178483
 C20orf79
chromosome 20 open reading frame 79
chr7_-_138458781 0.621 NM_130841
 ATP6V0A4
ATPase, H+ transporting, lysosomal V0 subunit a4
chr16_+_57050985 0.618 NM_032206
 NLRC5
NLR family, CARD domain containing 5
chr20_-_35488275 0.607 NM_199181
 KIAA0889
KIAA0889
chr8_+_54764367 0.606 NM_170587
 RGS20
regulator of G-protein signaling 20
chr5_+_35856990 0.593 NM_002185
 IL7R
interleukin 7 receptor

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 17 of 17 entries
enrichment   p-value GO term description
3.04 1.58e-07 GO:0022904 respiratory electron transport chain
2.53 1.27e-05 GO:0045333 cellular respiration
2.41 6.38e-05 GO:0022900 electron transport chain
2.06 2.56e-02 GO:0006006 glucose metabolic process
1.90 4.01e-04 GO:0015980 energy derivation by oxidation of organic compounds
1.80 4.28e-05 GO:0006091 generation of precursor metabolites and energy
1.34 1.72e-03 GO:0009653 anatomical structure morphogenesis
1.33 3.71e-03 GO:0007399 nervous system development
1.29 2.48e-06 GO:0048731 system development
1.26 1.07e-05 GO:0048856 anatomical structure development
1.24 1.48e-05 GO:0007275 multicellular organismal development
1.22 4.35e-03 GO:0006810 transport
1.21 9.09e-05 GO:0032502 developmental process
1.21 9.83e-03 GO:0051234 establishment of localization
1.17 4.22e-02 GO:0051179 localization
1.11 2.54e-02 GO:0008152 metabolic process
1.09 1.24e-07 GO:0009987 cellular process

Gene overrepresentation in compartment category:

Showing 1 to 15 of 15 entries
enrichment   p-value GO term description
3.02 1.09e-02 GO:0005747 mitochondrial respiratory chain complex I
3.02 1.09e-02 GO:0030964 NADH dehydrogenase complex
3.02 1.09e-02 GO:0045271 respiratory chain complex I
2.82 7.50e-04 GO:0000786 nucleosome
2.76 2.04e-08 GO:0044455 mitochondrial membrane part
2.68 1.35e-03 GO:0070469 respiratory chain
2.65 4.06e-03 GO:0005746 mitochondrial respiratory chain
2.03 6.01e-08 GO:0005743 mitochondrial inner membrane
1.92 4.37e-07 GO:0019866 organelle inner membrane
1.77 1.96e-06 GO:0031966 mitochondrial membrane
1.74 2.70e-06 GO:0005740 mitochondrial envelope
1.60 1.44e-06 GO:0031967 organelle envelope
1.59 1.49e-06 GO:0031975 envelope
1.59 6.59e-06 GO:0044429 mitochondrial part
1.37 4.85e-05 GO:0005739 mitochondrion

Gene overrepresentation in function category:

Showing 1 to 9 of 9 entries
enrichment   p-value GO term description
5.72 2.04e-02 GO:0003706 ligand-regulated transcription factor activity
2.98 3.94e-02 GO:0003954 NADH dehydrogenase activity
2.98 3.94e-02 GO:0008137 NADH dehydrogenase (ubiquinone) activity
2.98 3.94e-02 GO:0050136 NADH dehydrogenase (quinone) activity
2.74 1.66e-02 GO:0003707 steroid hormone receptor activity
2.73 1.12e-02 GO:0004879 ligand-dependent nuclear receptor activity
1.67 6.18e-03 GO:0016563 transcription activator activity
1.33 3.49e-02 GO:0001071 nucleic acid binding transcription factor activity
1.33 3.49e-02 GO:0003700 sequence-specific DNA binding transcription factor activity