Motif ID: NRF1.p2

Z-value: 1.764


Transcription factors associated with NRF1.p2:

Gene SymbolEntrez IDGene Name
NRF1 4899 nuclear respiratory factor 1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.p-valuePlot
NRF1chr7_+_129251579-0.271.9e-01Click!


Activity profile for motif NRF1.p2.

activity profile for motif NRF1.p2


Sorted Z-values histogram for motif NRF1.p2

Sorted Z-values for motif NRF1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NRF1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr19_-_50432672 1.820 IL4I1
interleukin 4 induced 1
chr19_-_50432647 1.735 IL4I1
interleukin 4 induced 1
chr5_+_52095929 1.605 PELO
pelota homolog (Drosophila)
chr9_+_110045551 1.457 RAD23B
RAD23 homolog B (S. cerevisiae)
chr6_-_41040160 1.388 NM_145063
 C6orf130
chromosome 6 open reading frame 130
chr19_-_7968426 1.378


chr7_-_44621837 1.250 TMED4
transmembrane emp24 protein transport domain containing 4
chr19_+_11071713 1.189 SMARCA4
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
chr15_+_41952641 1.183 MGA
MAX gene associated
chr19_+_11071719 1.157 SMARCA4
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
chr9_+_110045565 1.134 RAD23B
RAD23 homolog B (S. cerevisiae)
chr10_+_60028885 1.128 NM_018464
 CISD1
CDGSH iron sulfur domain 1
chr19_+_3762671 1.057 MRPL54
mitochondrial ribosomal protein L54
chr19_+_42724498 1.020 ZNF526
zinc finger protein 526
chr9_+_37079984 0.981 LOC100506710
endogenous Bornavirus-like nucleoprotein 2 pseudogene
chr7_-_44621784 0.977 TMED4
transmembrane emp24 protein transport domain containing 4
chr18_-_12884140 0.968 NM_001207013
NM_002828
NM_080422
NM_080423
 PTPN2



protein tyrosine phosphatase, non-receptor type 2



chr19_+_42724431 0.966 NM_133444
 ZNF526
zinc finger protein 526
chr7_-_44621819 0.965 NM_182547
 TMED4
transmembrane emp24 protein transport domain containing 4
chr19_+_3762650 0.957 NM_172251
 MRPL54
mitochondrial ribosomal protein L54

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 76 entries
enrichment   p-value GO term description
2.68 6.46e-04 GO:0006334 nucleosome assembly
2.62 6.80e-04 GO:0031497 chromatin assembly
2.59 2.04e-05 GO:0006323 DNA packaging
2.58 5.00e-02 GO:0006302 double-strand break repair
2.56 5.63e-04 GO:0065004 protein-DNA complex assembly
2.50 2.35e-03 GO:0034728 nucleosome organization
2.44 2.68e-05 GO:0071103 DNA conformation change
2.43 1.38e-04 GO:0006333 chromatin assembly or disassembly
2.42 2.31e-03 GO:0071824 protein-DNA complex subunit organization
2.41 2.45e-02 GO:0022904 respiratory electron transport chain
2.39 9.38e-03 GO:0007059 chromosome segregation
2.25 1.89e-05 GO:0000375 RNA splicing, via transesterification reactions
2.23 5.65e-05 GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
2.23 5.65e-05 GO:0000398 nuclear mRNA splicing, via spliceosome
2.22 1.84e-02 GO:0045333 cellular respiration
2.06 3.89e-14 GO:0051276 chromosome organization
2.05 5.05e-06 GO:0008380 RNA splicing
2.02 1.90e-05 GO:0000087 M phase of mitotic cell cycle
2.01 2.22e-05 GO:0048285 organelle fission
2.00 1.62e-04 GO:0034660 ncRNA metabolic process

Gene overrepresentation in compartment category:

Showing 1 to 20 of 41 entries
enrichment   p-value GO term description
2.79 1.65e-02 GO:0034708 methyltransferase complex
2.79 1.65e-02 GO:0035097 histone methyltransferase complex
2.67 2.15e-06 GO:0044455 mitochondrial membrane part
2.60 2.20e-03 GO:0031461 cullin-RING ubiquitin ligase complex
2.25 2.52e-02 GO:0032993 protein-DNA complex
2.13 3.87e-03 GO:0000151 ubiquitin ligase complex
2.13 3.87e-03 GO:0000793 condensed chromosome
2.11 7.97e-06 GO:0000785 chromatin
1.98 5.38e-11 GO:0030529 ribonucleoprotein complex
1.96 2.28e-09 GO:0044427 chromosomal part
1.91 2.99e-10 GO:0005694 chromosome
1.75 3.91e-18 GO:0005654 nucleoplasm
1.71 3.50e-08 GO:0044451 nucleoplasm part
1.68 2.27e-22 GO:0031981 nuclear lumen
1.64 1.32e-24 GO:0070013 intracellular organelle lumen
1.64 5.32e-24 GO:0044428 nuclear part
1.61 1.55e-23 GO:0031974 membrane-enclosed lumen
1.61 5.00e-23 GO:0043233 organelle lumen
1.60 1.43e-03 GO:0005730 nucleolus
1.58 9.00e-05 GO:0044429 mitochondrial part

Gene overrepresentation in function category:

Showing 1 to 13 of 13 entries
enrichment   p-value GO term description
3.20 8.93e-03 GO:0043021 ribonucleoprotein binding
2.25 6.84e-03 GO:0051082 unfolded protein binding
1.76 5.18e-11 GO:0003723 RNA binding
1.59 7.38e-03 GO:0016874 ligase activity
1.47 8.44e-22 GO:0003676 nucleic acid binding
1.40 3.83e-02 GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
1.39 2.41e-09 GO:0003677 DNA binding
1.39 4.61e-02 GO:0016817 hydrolase activity, acting on acid anhydrides
1.39 4.89e-02 GO:0016462 pyrophosphatase activity
1.31 1.79e-05 GO:0000166 nucleotide binding
1.17 4.66e-09 GO:0005515 protein binding
1.14 5.60e-03 GO:0003824 catalytic activity
1.09 9.34e-08 GO:0005488 binding