Motif ID: PAX2.p2

Z-value: 1.772


Transcription factors associated with PAX2.p2:

Gene SymbolEntrez IDGene Name
PAX2 5076 paired box 2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.p-valuePlot
PAX2chr10_+_1025053370.545.7e-03Click!


Activity profile for motif PAX2.p2.

activity profile for motif PAX2.p2


Sorted Z-values histogram for motif PAX2.p2

Sorted Z-values for motif PAX2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of PAX2.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr2_-_136875629 4.410 NM_003467
 CXCR4
chemokine (C-X-C motif) receptor 4
chr13_+_48877950 3.962 RB1
retinoblastoma 1
chr1_+_77747602 3.430 NM_174858
 AK5
adenylate kinase 5
chr11_-_119252267 3.331 USP2
ubiquitin specific peptidase 2
chr17_+_47866061 3.265 KAT7
K(lysine) acetyltransferase 7
chr17_+_47865980 3.171 NM_001199155
NM_001199156
NM_001199157
NM_001199158
NM_007067
 KAT7




K(lysine) acetyltransferase 7




chr8_-_9009050 3.095 NM_001201329
 PPP1R3B
protein phosphatase 1, regulatory subunit 3B
chr11_-_116968986 3.088 NM_025164
 SIK3
SIK family kinase 3
chr13_+_48877886 3.013 RB1
retinoblastoma 1
chr3_-_122512526 2.954 NM_024610
 HSPBAP1
HSPB (heat shock 27kDa) associated protein 1
chr15_-_70994608 2.930 NM_001008224
 UACA
uveal autoantigen with coiled-coil domains and ankyrin repeats
chr4_+_41614725 2.921 LIMCH1
LIM and calponin homology domains 1
chr17_-_46688279 2.905 HOXB7
homeobox B7
chr17_+_47866119 2.786 KAT7
K(lysine) acetyltransferase 7
chr12_-_9102193 2.776 M6PR
mannose-6-phosphate receptor (cation dependent)
chr13_+_48878025 2.763 RB1
retinoblastoma 1
chr18_+_77155943 2.745 NFATC1
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
chr6_-_144329342 2.704 NM_001080952
NM_001080953
NM_001080954
NM_001080956
NM_002656
NM_006718
 PLAGL1





HYMAI
pleiomorphic adenoma gene-like 1





hydatidiform mole associated and imprinted (non-protein coding)
chr17_-_46688362 2.695 NM_004502
 HOXB7
homeobox B7
chr4_+_41540320 2.667 LIMCH1
LIM and calponin homology domains 1

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 11 of 11 entries
enrichment   p-value GO term description
1.26 2.63e-04 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.26 7.34e-03 GO:0090304 nucleic acid metabolic process
1.23 3.46e-04 GO:0006807 nitrogen compound metabolic process
1.22 1.04e-03 GO:0034641 cellular nitrogen compound metabolic process
1.17 8.69e-03 GO:0051716 cellular response to stimulus
1.16 1.31e-02 GO:0044260 cellular macromolecule metabolic process
1.15 6.64e-05 GO:0044237 cellular metabolic process
1.15 1.25e-02 GO:0043170 macromolecule metabolic process
1.13 4.83e-04 GO:0008152 metabolic process
1.13 5.53e-03 GO:0044238 primary metabolic process
1.09 2.64e-06 GO:0009987 cellular process

Gene overrepresentation in compartment category:

Showing 1 to 20 of 20 entries
enrichment   p-value GO term description
2.06 2.05e-02 GO:0005765 lysosomal membrane
1.98 4.34e-03 GO:0044437 vacuolar part
1.97 7.60e-03 GO:0005774 vacuolar membrane
1.83 3.69e-04 GO:0000323 lytic vacuole
1.83 3.69e-04 GO:0005764 lysosome
1.81 6.52e-05 GO:0005773 vacuole
1.52 1.58e-02 GO:0005768 endosome
1.17 1.17e-06 GO:0044444 cytoplasmic part
1.14 1.14e-08 GO:0005737 cytoplasm
1.13 1.48e-07 GO:0043231 intracellular membrane-bounded organelle
1.12 1.57e-07 GO:0043227 membrane-bounded organelle
1.12 9.54e-03 GO:0005634 nucleus
1.12 1.08e-02 GO:0044422 organelle part
1.12 2.67e-02 GO:0044446 intracellular organelle part
1.11 4.23e-12 GO:0005622 intracellular
1.11 6.83e-12 GO:0044424 intracellular part
1.11 1.99e-07 GO:0043229 intracellular organelle
1.11 3.68e-07 GO:0043226 organelle
1.03 1.12e-02 GO:0005623 cell
1.03 1.45e-02 GO:0044464 cell part

Gene overrepresentation in function category:

Showing 1 to 2 of 2 entries
enrichment   p-value GO term description
1.19 3.40e-12 GO:0005515 protein binding
1.08 8.09e-07 GO:0005488 binding